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Journal Articles

TCRαβ/CD19 cell–depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis

Blood (2024) 143 (3): 279–289.

https://doi.org/10.1182/blood.2023021336

Published: 2024

Includes: Supplemental data

Journal Articles

N-803: a double-edged sword in haplo-NK therapy

Daniela Pende, Raffaella Meazza

Blood (2022) 139 (8): 1122–1124.

https://doi.org/10.1182/blood.2021014789

Published: 2022

Journal Articles

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

Pietro Merli, MD, Mattia Algeri, MD, Giuseppina Li Pira, PhD, Michela Falco, PhD, Daniela Pende, PhD, Valentina Bertaina, Daria Pagliara, MD PhD, Federica Galaverna, MD, Annalisa Ruggeri, MD PhD, Concetta Quintarelli, PhD, Lorenzo Moretta, MD PhD, Alice Bertaina, MD PhD, Franco Locatelli

Blood (2018) 132 (Supplement 1): 2169.

https://doi.org/10.1182/blood-2018-99-117136

Published: 2018

Journal Articles

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion

Blood (2017) 130 (5): 677–685.

https://doi.org/10.1182/blood-2017-04-779769

Published: 2017

Includes: Supplemental data

Journal Articles

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

Barbarella Lucarelli, MD, Alice Bertaina, MD PhD, Pietro Merli, MD, Concetta Quintarelli, PhD, Daniela Pende, MD, Michela Falco, PhD, Maria Giuseppina Cefalo, MD, Giuseppina Li Pira, PhD, Ignazio Caruana, PhD, Letizia Pomponia Brescia, MD, Luisa Strocchio, MD, Giuseppe Maria Milano, MD, Valentina Bertaina, PhD, Matilde Sinibaldi, PhD, Mattia Algeri, MD, Lorenzo Moretta, MD, Joanna Stanson, Annemarie Moseley, MD PhD, Franco Locatelli, MD

Blood (2016) 128 (22): 4683.

https://doi.org/10.1182/blood.V128.22.4683.4683

Published: 2016

Journal Articles

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

Hauke Stamm, MSc, Felix Klingler, cand. MD, Daniela Pende, MD, Eik Vettorazzi, MSc, Michael Heuser, MD, Ulrike Mock, PhD, Carsten Bokemeyer, MD, Roman Kischel, MD, Sabine Stienen, PhD, Matthias Friedrich, PhD, Michael Lutteropp, PhD, Dirk Nagorsen, MD, Jasmin Wellbrock, PhD, Walter Fiedler, MD

Blood (2015) 126 (23): 789.

https://doi.org/10.1182/blood.V126.23.789.789

Published: 2015

Journal Articles

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

Alice Bertaina, MDPhD, Barbarella Lucarelli, MD, Riccardo Masetti, MD, Pietro Merli, MD, Roberto Rondelli, MD, Giuseppina Li Pira, PhD, Marco Andreani, PhD, Lavinia Grapulin, MD, Daniela Pende, MD, Michela Falco, PhD, Maria Rita Pinto, MD, Valentina Bertaina, PhD, Maria Teresa Romano, MD, Stefano Ceccarelli, MD, Letizia Pomponia Brescia, MD, Daria Pagliara, MD, Alessandro Moretta, MD, Lorenzo Moretta, MD, Franco Locatelli, Prof, MD PhD

Blood (2015) 126 (23): 195.

https://doi.org/10.1182/blood.V126.23.195.195

Published: 2015

Journal Articles

Natural Killer (NK) Alloreactivity Seems Not to Play a Role in Preventing Leukemia Relapse in Unmanipulated Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide

Federica Galaverna, MD, Fabio Guolo, MD, Daniela Pende, MD, Alida Dominietto, MD, Raffaella Meazza, PhD, Michela Falco, PhD, Carmen Di Grazia, MD, Anna Maria Raiola, MD, Anna Ghiso, MD, Riccardo Varaldo, MD, Francesca Gualandi, MD, Carlo Marani, MD, Maria Teresa van Lint, MD, Roberto Massimo Lemoli, MD, Marco Gobbi, MD, Paola Minetto, MD, Andrea Bacigalupo, MD

Blood (2015) 126 (23): 2033.

https://doi.org/10.1182/blood.V126.23.2033.2033

Published: 2015

Journal Articles

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

Franco Locatelli, Prof, MD PhD, Pietro Merli, MD, Giuseppina Li Pira, PhD, Valentina Bertaina, PhD, Barbarella Lucarelli, MD, Letizia Pomponia Brescia, MD, Mauro Montanari, MD, Daniela Pende, MD, Michela Falco, PhD, Daria Pagliara, MD, Maria Giuseppina Cefalo, MD, Alessandro Moretta, MD, Concetta Quintarelli, PhD, Brigitte Strahm, MD, Waseem Qasim, MBBS PhD, Mary Slatter, Lorenzo Moretta, MD, Annemarie Moseley, MDPhD, Alice Bertaina, MDPhD

Blood (2015) 126 (23): 1931.

https://doi.org/10.1182/blood.V126.23.1931.1931

Published: 2015

Journal Articles

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ + /CD19 + lymphocytes

Irma Airoldi, Alice Bertaina, Ignazia Prigione, Alessia Zorzoli, Daria Pagliara, Claudia Cocco, Raffaella Meazza, Fabrizio Loiacono, Barbarella Lucarelli, Maria Ester Bernardo, Giulia Barbarito, Daniela Pende, Alessandro Moretta, Vito Pistoia, Lorenzo Moretta, Franco Locatelli

Blood (2015) 125 (15): 2349–2358.

https://doi.org/10.1182/blood-2014-09-599423

Published: 2015

Includes: Supplemental data

Journal Articles

HLA-haploidentical stem cell transplantation after removal of αβ + T and B cells in children with nonmalignant disorders

Blood (2014) 124 (5): 822–826.

https://doi.org/10.1182/blood-2014-03-563817

Published: 2014

Journal Articles

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

Blood (2013) 122 (21): 157.

https://doi.org/10.1182/blood.V122.21.157.157

Published: 2013

Journal Articles

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

Alice Bertaina, MD, Mariateresa Romano, MD, Sergio Rutella, MD PhD, Giuseppe Palumbo, MD, Daria Pagliara, MD, Stefano Ceccarelli, MD, Letizia P Brescia, MD, Giuseppina Li Pira, BSc, Francesca Cocca, MD, Maria Ester Bernardo, MD, Giuseppe M Milano, MD, Daniela Pende, PhD, Michela Falco, BSc, Lorenzo Moretta, MD, Franco Locatelli, MD, PhD

Blood (2012) 120 (21): 2018.

https://doi.org/10.1182/blood.V120.21.2018.2018

Published: 2012

Journal Articles

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

Blood (2012) 119 (12): 2754–2763.

https://doi.org/10.1182/blood-2011-08-374199

Published: 2012

Includes: Supplemental data

Journal Articles

Dual-functional capability of CD3 + CD56 + CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity

Alice Pievani, Gianmaria Borleri, Daniela Pende, Lorenzo Moretta, Alessandro Rambaldi, Josée Golay, Martino Introna

Blood (2011) 118 (12): 3301–3310.

https://doi.org/10.1182/blood-2011-02-336321

Published: 2011

Includes: Supplemental data

Journal Articles

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

Giuliana Magri, Aura Muntasell, Neus Romo, Andrea Sáez-Borderías, Daniela Pende, Daniel E. Geraghty, Hartmut Hengel, Ana Angulo, Alessandro Moretta, Miguel López-Botet

Blood (2011) 117 (3): 848–856.

https://doi.org/10.1182/blood-2010-08-301374

Published: 2011

Includes: Supplemental data

Journal Articles

Killer Ig–like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation

Lorenzo Moretta, Franco Locatelli, Daniela Pende, Emanuela Marcenaro, Maria Cristina Mingari, Alessandro Moretta

Blood (2011) 117 (3): 764–771.

https://doi.org/10.1182/blood-2010-08-264085

Published: 2011

Journal Articles

Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection

Aura Muntasell, Giuliana Magri, Daniela Pende, Ana Angulo, Miguel López-Botet

Blood (2010) 115 (25): 5170–5179.

https://doi.org/10.1182/blood-2009-11-256479

Published: 2010

Includes: Supplemental data

Journal Articles

Uptake of CCR7 and acquisition of migratory properties by human KIR + NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction

Emanuela Marcenaro, Claudia Cantoni, Silvia Pesce, Carola Prato, Daniela Pende, Sophie Agaugué, Lorenzo Moretta, Alessandro Moretta

Blood (2009) 114 (19): 4108–4116.

https://doi.org/10.1182/blood-2009-05-222265

Published: 2009

Journal Articles

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

Daniela Pende, Stefania Marcenaro, Michela Falco, Stefania Martini, Maria Ester Bernardo, Daniela Montagna, Elisa Romeo, Céline Cognet, Miryam Martinetti, Rita Maccario, Maria Cristina Mingari, Eric Vivier, Lorenzo Moretta, Franco Locatelli, Alessandro Moretta

Blood (2009) 113 (13): 3119–3129.

https://doi.org/10.1182/blood-2008-06-164103

Published: 2009

Includes: Supplemental data

NARROW

TCRαβ/CD19 cell–depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis

N-803: a double-edged sword in haplo-NK therapy

Alpha/Beta T-Cell and B-Cell Depletion HLA-Haploidentical Hematopoietic Stem Cell Transplantation Is an Effective Treatment for Children/Young Adults with Acute Leukemia

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion

T-Cell Depleted HLA-Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (haplo-HSCT) Followed By Donor Lymphocyte Infusion with T Cells Transduced with the Inducible Caspase 9 (iC9) Suicide Gene in Children with Hematological Malignancies

Expression of Novel Immune Checkpoint Molecules PVR and PVRL2 Confers a Negative Prognosis to Patients with Acute Myeloid Leukemia and Their Blockade Augments T-Cell Mediated Lysis of AML Cells Alone or in Combination with the BiTE ® Antibody Construct AMG 330

Children with Acute Leukemia Given Hematopoietic Stem Cell Transplantation (HSCT) from an HLA-Compatible Sibling, or an Unrelated Donor (UD) or an HLA-Haploidentical Relative after Alpha/Beta T-Cell Depletion Have a Comparable Outcome

Natural Killer (NK) Alloreactivity Seems Not to Play a Role in Preventing Leukemia Relapse in Unmanipulated Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide

Clinical Outcome after Adoptive Infusion of BPX-501 Cells (donor T cells transduced with iC9 suicide gene) in Children Given Alpha/Beta T-Cell Depleted HLA-Haploidentical Hematopoietic Stem Cell Transplantation (haplo-HSCT): Preliminary Results of a Phase I-II Trial

γδ T-cell reconstitution after HLA-haploidentical hematopoietic transplantation depleted of TCR-αβ + /CD19 + lymphocytes

HLA-haploidentical stem cell transplantation after removal of αβ + T and B cells in children with nonmalignant disorders

Removal Of Alpha/Beta+ T Cells and Of CD19+ B Cells From The Graft Translates Into Rapid Engraftment, Absence Of Visceral Graft-Versus-Host Disease and Low Transplant-Related Mortality In Children With Acute Leukemia Given HLA-Haploidentical Hematopoietic Stem Cell Transplantation

HLA Haploidentical Stem Cell Transplantation After Removal of αβ + T Lymphocytes and B Lymphocytes Is an Effective Treatment for Children with Life-Threatening, Non-Malignant Disorders

A prospective evaluation of degranulation assays in the rapid diagnosis of familial hemophagocytic syndromes

Dual-functional capability of CD3 + CD56 + CIK cells, a T-cell subset that acquires NK function and retains TCR-mediated specific cytotoxicity

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

Killer Ig–like receptor-mediated control of natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation

Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection

Uptake of CCR7 and acquisition of migratory properties by human KIR + NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction

Anti-leukemia activity of alloreactive NK cells in KIR ligand-mismatched haploidentical HSCT for pediatric patients: evaluation of the functional role of activating KIR and redefinition of inhibitory KIR specificity

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American Society of Hematology

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American Society of Hematology

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