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Scott W. Canna
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Journal Articles

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function

Jahnavi Aluri, Alicia Bach, Saara Kaviany, Luana Chiquetto Paracatu, Maleewan Kitcharoensakkul, Magdalena A. Walkiewicz, Christopher D. Putnam, Marwan Shinawi, Nermina Saucier, Elise M. Rizzi, Michael T. Harmon, Molly P. Keppel, Michelle Ritter, Morgan Similuk, Elaine Kulm, Michael Joyce, Adriana A. de Jesus, Raphaela Goldbach-Mansky, Yi-Shan Lee, Marina Cella, Peggy L. Kendall, Mary C. Dinauer, Jeffrey J. Bednarski, Christina Bemrich-Stolz, Scott W. Canna, Shirley M. Abraham, Matthew M. Demczko, Jonathan Powell, Stacie M. Jones, Amy M. Scurlock, Suk See De Ravin, Jack J. Bleesing, James A. Connelly, V. Koneti Rao, Laura G. Schuettpelz, Megan A. Cooper
Journal: Blood
Blood (2021) 137 (18): 2450–2462.
https://doi.org/10.1182/blood.2020009620
Published: 2021
Includes: Supplemental data
Journal Articles

Interleukin-18 and cytotoxic impairment are independent and synergistic causes of murine virus-induced hyperinflammation

Paul Tsoukas, Emily Rapp, Lauren Van Der Kraak, Eric S. Weiss, Vinh Dang, Corinne Schneider, Edwin Klein, Jennifer Picarsic, Rosalba Salcedo, C. Andrew Stewart, Scott W. Canna
Journal: Blood
Blood (2020) 136 (19): 2162–2174.
https://doi.org/10.1182/blood.2019003846
Published: 2020
Includes: Supplemental data
Journal Articles

Pediatric hemophagocytic lymphohistiocytosis

Scott W. Canna, Rebecca A. Marsh
Journal: Blood
Blood (2020) 135 (16): 1332–1343.
https://doi.org/10.1182/blood.2019000936
Published: 2020
Journal Articles

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome

Clinical Trials & Observations
Eric S. Weiss, Charlotte Girard-Guyonvarc’h, Dirk Holzinger, Adriana A. de Jesus, Zeshan Tariq, Jennifer Picarsic, Eduardo J. Schiffrin, Dirk Foell, Alexei A. Grom, Sandra Ammann, Stephan Ehl, Tomoaki Hoshino, Raphaela Goldbach-Mansky, Cem Gabay, Scott W. Canna
Journal: Blood
Blood (2018) 131 (13): 1442–1455.
https://doi.org/10.1182/blood-2017-12-820852
Published: 2018
Includes: Supplemental data
Journal Articles

Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

Rupali Das, Peng Guan, Leslee Sprague, Katherine Verbist, Paige Tedrick, Qi Angel An, Cheng Cheng, Makoto Kurachi, Ross Levine, E. John Wherry, Scott W. Canna, Edward M. Behrens, Kim E. Nichols
Journal: Blood
Blood (2016) 127 (13): 1666–1675.
https://doi.org/10.1182/blood-2015-12-684399
Published: 2016
Includes: Supplemental data