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Alexei A. Grom
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Journal Articles

Trials in Progress: A Two-Cohort, Open-Label, Single-Arm Study of Emapalumab, an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody, in Patients with Macrophage Activation Syndrome (MAS) in Rheumatic Diseases

Alexei A Grom, Jeanette Bachir, Veronica Asnaghi, Fabrizio De Benedetti
Journal: Blood
Blood (2021) 138 (Supplement 1): 4195.
https://doi.org/10.1182/blood-2021-146770
Published: 2021
Journal Articles

Macrophage Activation Syndrome (MAS) in Systemic Juvenile Idiopathic Arthritis (sJIA): Treatment with Emapalumab, an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody

Fabrizio De Benedetti, Alexei A Grom, Paul Brogan, Claudia Bracaglia, Manuela Pardeo, Giulia Marucci, Despina Eleftheriou, Charalampia Papadopoulou, Pierre Quartier, Jordi Antón, Rikke Frederiksen, Veronica Asnaghi, Maria Ballabio, Cristina de Min
Journal: Blood
Blood (2021) 138 (Supplement 1): 2058.
https://doi.org/10.1182/blood-2021-147596
Published: 2021
Journal Articles

Safety and Efficacy of Emapalumab in Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis

Franco Locatelli, Michael B. Jordan, MD, Carl E. Allen, MDPhD, Simone Cesaro, MD, Carmelo Rizzari, MD, Anupama Rao, MD, Barbara Degar, MD, Timothy Garrington, Julian Sevilla, MD PhD, Maria Caterina Putti, MD, Franca Fagioli, MD, Martina Ahlmann, MD, Jose-Luis Dapena, MD, Alexei A. Grom, MD, Fabrizio De Benedetti, MD, Walter Giovanni Ferlin, PhD, Maria Ballabio, MD, Cristina De Min, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): LBA-6.
https://doi.org/10.1182/blood-2018-120810
Published: 2018
Journal Articles

Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome

Clinical Trials & Observations
Eric S. Weiss, Charlotte Girard-Guyonvarc’h, Dirk Holzinger, Adriana A. de Jesus, Zeshan Tariq, Jennifer Picarsic, Eduardo J. Schiffrin, Dirk Foell, Alexei A. Grom, Sandra Ammann, Stephan Ehl, Tomoaki Hoshino, Raphaela Goldbach-Mansky, Cem Gabay, Scott W. Canna
Journal: Blood
Blood (2018) 131 (13): 1442–1455.
https://doi.org/10.1182/blood-2017-12-820852
Published: 2018
Includes: Supplemental data
Journal Articles

A Novel Targeted Approach to the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) with an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody (mAb), NI-0501: First Results from a Pilot Phase 2 Study in Children with Primary HLH

Michael Jordan, MD, Franco Locatelli Prof, MD, PhD, Carl Allen, MD, PhD, Fabrizio De Benedetti, MD, PhD, Alexei A. Grom, Maria Ballabio, MD, Walter Giovanni Ferlin, PhD, NI-0501-04 Study Group, Cristina De Min, MD
Journal: Blood
Blood (2015) 126 (23): LBA-3.
https://doi.org/10.1182/blood.V126.23.LBA-3.LBA-3
Published: 2015
Journal Articles

Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis

e-blood
Janos Sumegi, Shawnagay V. Nestheide, Michael G. Barnes, Joyce Villanueva, Kejian Zhang, Alexei A. Grom, Alexandra H. Filipovich
Journal: Blood
Blood (2013) 121 (7): e14–e24.
https://doi.org/10.1182/blood-2012-05-425769
Published: 2013
Includes: Supplemental data
Journal Articles

Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis

e-blood
Janos Sumegi, Michael G. Barnes, Shawnagay V. Nestheide, Susan Molleran-Lee, Joyce Villanueva, Kejian Zhang, Kimberly A. Risma, Alexei A. Grom, Alexandra H. Filipovich
Journal: Blood
Blood (2011) 117 (15): e151–e160.
https://doi.org/10.1182/blood-2010-08-300046
Published: 2011
Includes: Supplemental data