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Journal Articles

Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

Elisabet Bergsten, AnnaCarin Horne, Maurizio Aricó, Itziar Astigarraga, R. Maarten Egeler, Alexandra H. Filipovich, Eiichi Ishii, Gritta Janka, Stephan Ladisch, Kai Lehmberg, Kenneth L. McClain, Milen Minkov, Scott Montgomery, Vasanta Nanduri, Diego Rosso, Jan-Inge Henter

Blood (2017) 130 (25): 2728–2738.

https://doi.org/10.1182/blood-2017-06-788349

Published: 2017

Journal Articles

Alemtuzumab levels impact acute GVHD, mixed chimerism, and lymphocyte recovery following alemtuzumab, fludarabine, and melphalan RIC HCT

Rebecca A. Marsh, Adam Lane, Parinda A. Mehta, Lisa Neumeier, Sonata Jodele, Stella M. Davies, Alexandra H. Filipovich

Blood (2016) 127 (4): 503–512.

https://doi.org/10.1182/blood-2015-07-659672

Published: 2016

Journal Articles

Accuracy of flow cytometric perforin screening for detecting patients with FHL due to PRF1 mutations

Manar Abdalgani, Alexandra H. Filipovich, Sharon Choo, Kejian Zhang, Carrie Gifford, Joyce Villanueva, Jack J. Bleesing, Rebecca A. Marsh

Blood (2015) 126 (15): 1858–1860.

https://doi.org/10.1182/blood-2015-06-648659

Published: 2015

Includes: Supplemental data

Journal Articles

Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Kejian Zhang, Shanmuganathan Chandrakasan, Heather Chapman, C. Alexander Valencia, Ammar Husami, Diane Kissell, Judith A. Johnson, Alexandra H. Filipovich

Blood (2014) 124 (8): 1331–1334.

https://doi.org/10.1182/blood-2014-05-573105

Published: 2014

Journal Articles

Adolescents and Young Adults With Hemophagocytic Lymphohistiocytosis Who Undergo Allogeneic Hematopoietic Cell Transplantation Are At Increased Risk Of Mortality Compared To Younger Patients

Shanmuganathan Chandrakasan, MD, Rebecca Marsh, MD, Michael Grimley, MD, Jack Bleesing, MD, PhD, Michael Jordan, MD, Alexandra H. Filipovich, MD

Blood (2013) 122 (21): 2087.

https://doi.org/10.1182/blood.V122.21.2087.2087

Published: 2013

Journal Articles

Immune Reconstitution and Preliminary Safety Analysis Of 9 Patients Treated With Somatic Gene Therapy For X-Linked Severe Combined Immunodeficiency (SCID-X1) With a Self-Inactivating Gammaretroviral Vector

Blood (2013) 122 (21): 715.

https://doi.org/10.1182/blood.V122.21.715.715

Published: 2013

Journal Articles

Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis

Janos Sumegi, Shawnagay V. Nestheide, Michael G. Barnes, Joyce Villanueva, Kejian Zhang, Alexei A. Grom, Alexandra H. Filipovich

Blood (2013) 121 (7): e14–e24.

https://doi.org/10.1182/blood-2012-05-425769

Published: 2013

Includes: Supplemental data

Journal Articles

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

Blood (2013) 121 (6): 877–883.

https://doi.org/10.1182/blood-2012-06-432500

Published: 2013

Journal Articles

Prenatal Origin of Monosomy 7 in Very Young Children.

Parinda A. Mehta, M.D., Mark Wunderlich, MS, Teresa Smolarek, PhD, Stella M. Davies, MBBS, PhD, Sarah Zimmerman, PhD, Alexandra H. Filipovich, MD, Emmett H. Broxson, Jr., MD, Jose A. Cancelas, M.D. PhD., James C. Mulloy, PhD

Blood (2012) 120 (21): 2557.

https://doi.org/10.1182/blood.V120.21.2557.2557

Published: 2012

Journal Articles

Hemophagocytic Lymphohistiocytosis: Update of Biology and Treatment Options

Alexandra H. Filipovich, MD

Blood (2012) 120 (21): SCI-9.

https://doi.org/10.1182/blood.V120.21.SCI-9.SCI-9

Published: 2012

Journal Articles

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

Shaojing Ye, Zubair A. Karim, Rania Al Hawas, Jeffery E. Pessin, Alexandra H. Filipovich, Sidney W. Whiteheart

Blood (2012) 120 (12): 2484–2492.

https://doi.org/10.1182/blood-2012-05-430603

Published: 2012

Includes: Supplemental data

Journal Articles

Munc18b/STXBP2 is required for platelet secretion

Rania Al Hawas, Qiansheng Ren, Shaojing Ye, Zubair A. Karim, Alexandra H. Filipovich, Sidney W. Whiteheart

Blood (2012) 120 (12): 2493–2500.

https://doi.org/10.1182/blood-2012-05-430629

Published: 2012

Journal Articles

Hypomorphic mutations in PRF1 , MUNC13-4 , and STXBP2 are associated with adult-onset familial HLH

Kejian Zhang, Michael B. Jordan, Rebecca A. Marsh, Judith A. Johnson, Diane Kissell, Jarek Meller, Joyce Villanueva, Kimberly A. Risma, Qian Wei, Peter S. Klein, Alexandra H. Filipovich

Blood (2011) 118 (22): 5794–5798.

https://doi.org/10.1182/blood-2011-07-370148

Published: 2011

Journal Articles

Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

Helena Trottestam, AnnaCarin Horne, Maurizio Aricò, R. Maarten Egeler, Alexandra H. Filipovich, Helmut Gadner, Shinsaku Imashuku, Stephan Ladisch, David Webb, Gritta Janka, Jan-Inge Henter, for the Histiocyte Society

Blood (2011) 118 (17): 4577–4584.

https://doi.org/10.1182/blood-2011-06-356261

Published: 2011

Includes: Supplemental data

Journal Articles

How I treat hemophagocytic lymphohistiocytosis

Michael B. Jordan, Carl E. Allen, Sheila Weitzman, Alexandra H. Filipovich, Kenneth L. McClain

Blood (2011) 118 (15): 4041–4052.

https://doi.org/10.1182/blood-2011-03-278127

Published: 2011

Journal Articles

Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis

Janos Sumegi, Michael G. Barnes, Shawnagay V. Nestheide, Susan Molleran-Lee, Joyce Villanueva, Kejian Zhang, Kimberly A. Risma, Alexei A. Grom, Alexandra H. Filipovich

Blood (2011) 117 (15): e151–e160.

https://doi.org/10.1182/blood-2010-08-300046

Published: 2011

Includes: Supplemental data

Journal Articles

Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation

Rebecca A. Marsh, Gretchen Vaughn, Mi-Ok Kim, Dandan Li, Sonata Jodele, Sarita Joshi, Parinda A. Mehta, Stella M. Davies, Michael B. Jordan, Jack J. Bleesing, Alexandra H. Filipovich

Blood (2010) 116 (26): 5824–5831.

https://doi.org/10.1182/blood-2010-04-282392

Published: 2010

Includes: Supplemental data

Journal Articles

X-linked lymphoproliferative syndromes: brothers or distant cousins?

Alexandra H. Filipovich, Kejian Zhang, Andrew L. Snow, Rebecca A. Marsh

Blood (2010) 116 (18): 3398–3408.

https://doi.org/10.1182/blood-2010-03-275909

Published: 2010

Journal Articles

XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

Rebecca A. Marsh, Lisa Madden, Brenda J. Kitchen, Rajen Mody, Brad McClimon, Michael B. Jordan, Jack J. Bleesing, Kejian Zhang, Alexandra H. Filipovich

Blood (2010) 116 (7): 1079–1082.

https://doi.org/10.1182/blood-2010-01-256099

Published: 2010

Includes: Supplemental data

Journal Articles

Perforin Polymorphism A91V and Susceptibility to Childhood Acute Lymphoblastic Leukemia (ALL).

Parinda A. Mehta, MD, Stella M. Davies, MBBS, Ashish Kumar, MD, Meenakshi Devidas, PhD, Susan Lee, BS, Tiffany Wilke, BS, James Elliott, BS, MBA, Joyce Villanueva, BS, Jeanette Pullen, MD, Yetnayet Zewge, Alexandra H. Filipovich, MD

Blood (2005) 106 (11): 1453.

https://doi.org/10.1182/blood.V106.11.1453.1453

Published: 2005

NARROW

Confirmed efficacy of etoposide and dexamethasone in HLH treatment: long-term results of the cooperative HLH-2004 study

Alemtuzumab levels impact acute GVHD, mixed chimerism, and lymphocyte recovery following alemtuzumab, fludarabine, and melphalan RIC HCT

Accuracy of flow cytometric perforin screening for detecting patients with FHL due to PRF1 mutations

Synergistic defects of different molecules in the cytotoxic pathway lead to clinical familial hemophagocytic lymphohistiocytosis

Adolescents and Young Adults With Hemophagocytic Lymphohistiocytosis Who Undergo Allogeneic Hematopoietic Cell Transplantation Are At Increased Risk Of Mortality Compared To Younger Patients

Immune Reconstitution and Preliminary Safety Analysis Of 9 Patients Treated With Somatic Gene Therapy For X-Linked Severe Combined Immunodeficiency (SCID-X1) With a Self-Inactivating Gammaretroviral Vector

Gene-expression signatures differ between different clinical forms of familial hemophagocytic lymphohistiocytosis

Allogeneic hematopoietic cell transplantation for XIAP deficiency: an international survey reveals poor outcomes

Prenatal Origin of Monosomy 7 in Very Young Children.

Hemophagocytic Lymphohistiocytosis: Update of Biology and Treatment Options

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

Munc18b/STXBP2 is required for platelet secretion

Hypomorphic mutations in PRF1 , MUNC13-4 , and STXBP2 are associated with adult-onset familial HLH

Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

How I treat hemophagocytic lymphohistiocytosis

Gene expression profiling of peripheral blood mononuclear cells from children with active hemophagocytic lymphohistiocytosis

Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation

X-linked lymphoproliferative syndromes: brothers or distant cousins?

XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease

Perforin Polymorphism A91V and Susceptibility to Childhood Acute Lymphoblastic Leukemia (ALL).

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American Society of Hematology

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American Society of Hematology

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