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Journal Articles

Emapalumab, a Fully Human Anti-Interferon Gamma Monoclonal Antibody, in Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis: Long-Term Follow-up of a Phase 2/3 Study

Michael B. Jordan, Carl Allen, Anupama Rao, Carmelo Rizzari, Simone Cesaro, Maria Caterina Putti, Julian Sevilla, Cristina de Min, Maria Ballabio, Veronica Asnaghi, Anna Stoltenberg, Radmila Kanceva, Franco Locatelli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1174.
https://doi.org/10.1182/blood-2023-179362
Published: 2023
Journal Articles

Macrophage Activation Syndrome (MAS) in Systemic Juvenile Idiopathic Arthritis (sJIA): Treatment with Emapalumab, an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody

Fabrizio De Benedetti, Alexei A Grom, Paul Brogan, Claudia Bracaglia, Manuela Pardeo, Giulia Marucci, Despina Eleftheriou, Charalampia Papadopoulou, Pierre Quartier, Jordi Antón, Rikke Frederiksen, Veronica Asnaghi, Maria Ballabio, Cristina de Min
Journal: Blood
Blood (2021) 138 (Supplement 1): 2058.
https://doi.org/10.1182/blood-2021-147596
Published: 2021
Journal Articles

Safety of Emapalumab in Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis (HLH): Relationship to Treatment Exposure

Michael B Jordan, Franco Locatelli, Philippe Jacqmin, Christian Laveille, Eric Snoeck, Cristina de Min
Journal: Blood
Blood (2021) 138 (Supplement 1): 2061.
https://doi.org/10.1182/blood-2021-150256
Published: 2021
Journal Articles

Sensitivity Analysis of Overall Response Rate (ORR) with Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis (HLH)

Franco Locatelli, MD PhD, Michael B. Jordan, MD, Carl Allen, Simone Cesaro, MD, Carmelo Rizzari, Anupama Rao, Barbara Degar, MD, Tim Garrington, MD, Julian Sevilla, MD PhD, Maria Caterina Putti, MD, Franca Fagioli, MD, Martina Ahlmann, MD, Jose-Luis Dapena Diaz, Michael Henry, MD, Fabrizio De Benedetti, MD, Alexei Grom, Anna Stoltenberg, Mårten Vågerö, Cristina de Min
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
https://doi.org/10.1182/blood-2020-140692
Published: 2020
Journal Articles

Population Pharmacokinetic Analysis of Emapalumab, a Fully Human, Anti-Interferon Gamma Monoclonal Antibody, in Children with Primary Hemophagocytic Lymphohistiocytosis

Christian Laveille, Philippe Jacqmin, Kathy de Graaf, Cristina de Min
Journal: Blood
Blood (2020) 136 (Supplement 1): 20.
https://doi.org/10.1182/blood-2020-140755
Published: 2020
Journal Articles

Safety of Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis: Results of the Primary Analysis of the Pivotal Phase 2/3 Study

Franco Locatelli, MD PhD, Michael B. Jordan, MD, Carl Allen, Simone Cesaro, MD, Carmelo Rizzari, Anupama Rao, Barbara Degar, MD, Tim Garrington, MD, Julian Sevilla, MD PhD, Maria Caterina Putti, MD, Franca Fagioli, MD, Martina Ahlmann, MD, Jose-Luis Dapena Diaz, Michael Henry, MD, Fabrizio De Benedetti, MD, Alexei Grom, Cristina de Min
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-140766
Published: 2020
Journal Articles

An Adaptive Design Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients with Non-Primary Hemophagocytic Lymphohistiocytosis

Veronica Asnaghi, MD, Maria Ballabio, MD, Philippe Jacqmin, Kathy de Graaf, Cristina De Min, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2333.
https://doi.org/10.1182/blood-2019-123995
Published: 2019
Journal Articles

Safety and Efficacy of Emapalumab in Pediatric Patients with Primary Hemophagocytic Lymphohistiocytosis

Franco Locatelli, Michael B. Jordan, MD, Carl E. Allen, MDPhD, Simone Cesaro, MD, Carmelo Rizzari, MD, Anupama Rao, MD, Barbara Degar, MD, Timothy Garrington, Julian Sevilla, MD PhD, Maria Caterina Putti, MD, Franca Fagioli, MD, Martina Ahlmann, MD, Jose-Luis Dapena, MD, Alexei A. Grom, MD, Fabrizio De Benedetti, MD, Walter Giovanni Ferlin, PhD, Maria Ballabio, MD, Cristina De Min, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): LBA-6.
https://doi.org/10.1182/blood-2018-120810
Published: 2018
Journal Articles

A Novel Targeted Approach to the Treatment of Hemophagocytic Lymphohistiocytosis (HLH) with an Anti-Interferon Gamma (IFNγ) Monoclonal Antibody (mAb), NI-0501: First Results from a Pilot Phase 2 Study in Children with Primary HLH

Michael Jordan, MD, Franco Locatelli Prof, MD, PhD, Carl Allen, MD, PhD, Fabrizio De Benedetti, MD, PhD, Alexei A. Grom, Maria Ballabio, MD, Walter Giovanni Ferlin, PhD, NI-0501-04 Study Group, Cristina De Min, MD
Journal: Blood
Blood (2015) 126 (23): LBA-3.
https://doi.org/10.1182/blood.V126.23.LBA-3.LBA-3
Published: 2015