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Bernd Gruhn
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Journal Articles

Addition of Anti-T-Lymphocyte-Globuline As Graft Versus Host Disease Prophylaxis for Matched Unrelated Donors Equalizes Outcomes with Matched Sibling Donors: Results from the AML SCT-BFM 2007 Trial

Martin G. Sauer, Peter Lang, Michael H Albert, Peter Bader, Ursula Creutzig, Matthias Eyrich, Johann Greil, Bernd Gruhn, Wolfgang Holter, Thomas Klingebiel, Bernhard Kremens, Christine Mauz-Körholz, Roland Meisel, Kirsten Mischke, Ingo Muller, Charlotte Marie Niemeyer, Christina Peters, Dirk Reinhardt, Birgit Burkhardt, Paul-Gerhardt Schlegel, Ansgar Schulz, Johanna Schrum, Petr Sedlacek, Brigitte Strahm, Wilhelm Woessmann, Rupert Handgretinger, Martin Zimmermann, Arndt Borkhardt
Journal: Blood
Blood (2024) 144 (Supplement 1): 3563.
https://doi.org/10.1182/blood-2024-200574
Published: 2024
Journal Articles

Efficacy and Safety of Donor Lymphocyte Infusion after Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients

Bernd Gruhn, Dinah Walther, Jana Ernst, Till Milde
Journal: Blood
Blood (2024) 144 (Supplement 1): 2112.
https://doi.org/10.1182/blood-2024-207902
Published: 2024
Journal Articles

A Reduced Daunorubicin Dose during Induction Is Equally Effective As Standard Dose in Children with Acute Lymphoblastic Leukemia (ALL) and Favorable Prognostic Features: Long-Term Results of the Phase 3 Trial AIEOP-BFM ALL 2009

Martin Schrappe, Hanna Marie Gottschalk, Valentino Conter, Gunnar Cario, Jan Stary, Anja Möricke, Michael Dworzak, Andishe Attarbaschi, Draga Barbaric, Franco Locatelli, Nicole Bodmer, Sarah Elitzur, Daniela Silvestri, Luciano Dalla-Pozza, Bernd Gruhn, Shai Izraeli, Carmelo Rizzari, Jean-Pierre Bourquin, Andrea Biondi, Maria Grazia Valsecchi, Martin Zimmermann
Journal: Blood
Blood (2024) 144 (Supplement 1): 309.
https://doi.org/10.1182/blood-2024-204943
Published: 2024
Journal Articles

Analysis of Laboratory Parameters before the Occurrence of Hepatic Sinusoidal Obstruction Syndrome in Pediatric Patients after Hematopoietic Stem Cell Transplantation

Bernd Gruhn, Lorena Johann
Journal: Blood
Blood (2023) 142 (Supplement 1): 2164.
https://doi.org/10.1182/blood-2023-173099
Published: 2023
Journal Articles

Impact of Additional Intensive L-Asparaginase Therapy during Consolidation Phase for High-Risk Acute Lymphoblastic Leukemia: Results of a Randomized Controlled Trial in the AIEOP-BFM ALL 2009 Protocol

Valentino Conter, Maria Grazia Valsecchi, Gunnar Cario, Martin Zimmermann, Andishe Attarbaschi, Jan Stary, Felix Niggli, Luciano Dalla Pozza, Sarah Elitzur, Daniela Silvestri, Franco Locatelli, Anja Moericke, Gernot Engstler, Petr Smisek, Nicole Bodmer, Draga Barbaric, Shai Izraeli, Carmelo Rizzari, Joachim Boos, Barbara Buldini, Claudia Lanvers-Kaminsky, Giovanni Cazzaniga, Bernd Gruhn, Andrea Biondi, Martin Schrappe
Journal: Blood
Blood (2022) 140 (Supplement 1): 109–111.
https://doi.org/10.1182/blood-2022-166583
Published: 2022
Journal Articles

Superior Overall Survival with Blinatumomab Versus Chemotherapy As Pre-Transplant Consolidation Treatment in Children with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL): Longer Follow-up (FU) of a Phase 3 Randomized Controlled Trial (RCT)

Franco Locatelli, Gerhard Zugmaier, Carmelo Rizzari, Joan D Morris, Bernd Gruhn, Thomas Klingebiel, Rosanna Parasole, Christin Linderkamp, Christian Flotho, Arnaud Petit, Concetta Micalizzi, Yi Zeng, Deepali Dilip Pilankar, William N Kormany, Cornelia Eckert, Anja Moericke, Mary Sartor, Ondrej Hrusak, Christina Peters, Vaskar Saha, Luciana Vinti, Arend von Stackelberg
Journal: Blood
Blood (2021) 138 (Supplement 1): 1231.
https://doi.org/10.1182/blood-2021-145476
Published: 2021
Journal Articles

Association of Donor and Recipient Interleukin-1 Gene Single Nucleotide Polymorphisms with Outcome after Allogeneic Hematopoietic Stem Cell Transplantation in Childhood

Bernd Gruhn, Susan Wittig, Katharina Kämpfner
Journal: Blood
Blood (2021) 138 (Supplement 1): 3902.
https://doi.org/10.1182/blood-2021-150895
Published: 2021
Journal Articles

Analysis of Risk Factors for Hepatic Sinusoidal Obstruction Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients

Bernd Gruhn, Grit Brodt, MD, Jana Ernst, MD, Jaspar Kloehn
Journal: Blood
Blood (2020) 136 (Supplement 1): 28.
https://doi.org/10.1182/blood-2020-133973
Published: 2020
Journal Articles

Prospective Clinical Phase II Results on Treosulfan-Based Conditioning Treatment of 70 Paediatric Patients with Haematological Malignancies

Krzysztof Kalwak, MD, Peter Bader, MD PhD, Jan Styczynski, PhD, Bernd Gruhn, MD, Katharine Patrick, MD, Petr Sedlacek, MD, Daniel Stachel, MD, Karl-Walter Sykora, MD, Selim Corbacioglu, MD, Katarzyna Drabko, MD, Franca Fagioli, MD, Johann Greil, MD, Franco Locatelli, Ingo Müller, MD, Bernhard Kremens, MD PhD, Paul G. Schlegel, MD, Jolanta Gozdzik, MD PhD, Birgit Burkhardt, MD PhD, Monika Mielcarek-Siedziuk, MD, Ajay Vora, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3354.
https://doi.org/10.1182/blood-2018-99-110980
Published: 2018
Journal Articles

Effects of Various ATG Doses on Rejection Rate and Immune Recovery in Haploidentical T and B Cell Depleted Stem Cell Transplantation

Peter J. Lang, MD, Friedhelm Schuster, Bernd Gruhn, Roland Meisel, MD, Patrick Schlegel, MD, Anne-Marie Lang, Chihab Klose, Wolfgang Schwinger, MD, Tobias F. Feuchtinger, Prof. Dr. MD, Heiko-Manuel Teltschik, Holger Martinius, Michael Schumm, DVM, Rupert Handgretinger, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3250.
https://doi.org/10.1182/blood.V130.Suppl_1.3250.3250
Published: 2017
Journal Articles

AML SCT-BFM 2007: Results of the Prospective Hematopoietic Stem Cell Transplantation (HCT) Trial of the Berlin-Frankfurt-Münster (BFM) Study Group for Children with Very High Risk Acute Myeloid Leukemia

Martin G. Sauer, Peter J. Lang, MD, Michael H. Albert, Peter Bader, MD PhD, Daniel Breuer, Ursula Creutzig, Matthias K. Eyrich, MD, Johann Greil, MD, Bernd Gruhn, Wolfgang Holter, Thomas Klingebiel, MD, Bernhard Kremens, MD PhD, Heiko vd Leyen, Christine Mauz-Körholz, Roland Meisel, MD, Kirsten Mischke, Ingo Müller, Charlotte M. Niemeyer, MD, Christina Peters, MD, Dirk Reinhardt, MD, Claudia Rossig, MD, Paul G. Schlegel, MD, Ansgar S. Schulz, MD, Johanna Schrum, MD, Petr Sedlacek, MD, Brigitte Strahm, PD Dr., Wilhelm Woessmann, Martin Zimmermann, PhD, Rupert Handgretinger, MD PhD, Arndt Borkhardt, Prof MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 599.
https://doi.org/10.1182/blood.V130.Suppl_1.599.599
Published: 2017
Journal Articles

Prevalence and Dynamics of Clonal Hematopoiesis Caused By Leukemia Associated Mutations in Elderly Individuals without Hematologic Disorders

Thomas Ernst, MD, Jenny Rinke, Danica Midic, Violetta Müller, Anja Waldau, Alexander Kaiser, MD, Bernd Gruhn, Jürgen Landschulze, MD, Frank Pester, MD, Andreas Hochhaus, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1141.
https://doi.org/10.1182/blood.V130.Suppl_1.1141.1141
Published: 2017
Journal Articles

Protocol II vs protocol III given twice during reinduction therapy in children with medium-risk ALL

Clinical Trials & Observations
Franco Locatelli, Maria Grazia Valsecchi, Anja Möricke, Martin Zimmermann, Bernd Gruhn, Andrea Biondi, Andreas E. Kulozik, Daniela Silvestri, Nicole Bodmer, Maria Caterina Putti, Stefan Burdach, Concetta Micalizzi, Andrea Teigler-Schlegel, Jörg Ritter, Andrea Pession, Gunnar Cario, Stefan Bielack, Giuseppe Basso, Thomas Klingebiel, Luciana Vinti, Carmelo Rizzari, Andishe Attarbaschi, Nicola Santoro, Rosanna Parasole, Georg Mann, Leonid Karawajew, Oskar A. Haas, Valentino Conter, Martin Schrappe
Journal: Blood
Blood (2017) 130 (19): 2146–2149.
https://doi.org/10.1182/blood-2017-05-782086
Published: 2017
Includes: Supplemental data
Journal Articles

CTLA-4 Polymorphisms: Influence on Transplant-Related Mortality and Survival in Children Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Bernd Gruhn, MD, Susan Wittig, Thomas Ernst, MD, Judith Hammrich
Journal: Blood
Blood (2016) 128 (22): 67.
https://doi.org/10.1182/blood.V128.22.67.67
Published: 2016
Journal Articles

The Effect of Measurable Residual Disease at the Time of Allogeneic Hematopoietic Cell Transplantation on Outcomes in Patients with Acute Myeloid Leukemia: A Meta-Analysis

Sarah A. Buckley, MD, Brent L. Wood, MD PhD, Megan Othus, PhD, Christopher S. Hourigan, MD PhD, Celalettin Ustun, MD, Michael A. Linden, MD PhD, Todd E. DeFor, MS, Michele Malagola, MD PhD, Christopher G. Kanakry, MD, Bernd Gruhn, MD, Beth Devine, PhD PharmD, Roland B. Walter, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2842.
https://doi.org/10.1182/blood.V128.22.2842.2842
Published: 2016
Journal Articles

Prevalence and Dynamics of BCR-ABL Independent Gene Mutations in Patients with Chronic Myeloid Leukemia

Thomas Ernst, MD, Jenny Rinke, Melinda Busch, Jana Ernst, MD, Ellen Obstfelder, Mathias Schmidt, MD, Vivien Schäfer, Anja Waldau, Nils Winkelmann, MD, Bernd Gruhn, MD, Andreas Hochhaus, MD
Journal: Blood
Blood (2016) 128 (22): 1221.
https://doi.org/10.1182/blood.V128.22.1221.1221
Published: 2016
Journal Articles

Mother Donors Improve Outcomes after HLA Haploidentical Hematopoietic Transplantation: A Retrospective Study By the Cell Therapy and Immunobiology Working Party of the EBMT

Andrea Velardi, Loredana Ruggeri, Dimitris Ziagkos, Anja van Biezen, Mara Merluzzi, Attilio Bondanza, MD PhD, Nathasja Bootsman, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Maddalena Noviello, PhD, Fabio Ciceri, MD, Thomas Klingebiel, MD, Yener Koc, MD, Hendrik Veelken, MD PhD, Franco Locatelli, MD, William Arcese, Bernd Gruhn, MD, Flavia Salvi, Chiara Bonini, MD, Jon J. van Rood, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3472.
https://doi.org/10.1182/blood.V128.22.3472.3472
Published: 2016
Journal Articles

The minimum required level of donor chimerism in hereditary hemophagocytic lymphohistiocytosis

Clinical Trials & Observations
Bernd Hartz, Rebecca Marsh, Kanchan Rao, Jan-Inge Henter, Michael Jordan, Lisa Filipovich, Peter Bader, Rita Beier, Birgit Burkhardt, Roland Meisel, Ansgar Schulz, Beate Winkler, Michael H. Albert, Johann Greil, Gülsün Karasu, Wilhelm Woessmann, Selim Corbacioglu, Bernd Gruhn, Wolfgang Holter, Jörn-Sven Kühl, Peter Lang, Markus G. Seidel, Paul Veys, Alexandra Löfstedt, Sandra Ammann, Stephan Ehl, Gritta Janka, Ingo Müller, Kai Lehmberg
Journal: Blood
Blood (2016) 127 (25): 3281–3290.
https://doi.org/10.1182/blood-2015-12-684498
Published: 2016
Includes: Supplemental data
Journal Articles

An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT

Attilio Bondanza, MD PhD, Loredana Ruggeri, Dimitris Ziagkos, Chiara Bonini, MD, Christian Chabannon, Natalia Bootsman, Cora Knol-Bout, Liesbeth De Wreede, Maddalena Noviello, PhD, Lara Crucitti, MD, Luca Vago, MD PhD, Alessandra Carotti, Adelmo Terenzi, Mara Merluzzi, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Joan Hendrik Veelken, Yener Koc, MD, Peter Bader, MD, Bernd Gruhn, MD, Franco Locatelli, MD PhD, Fabio Ciceri, MD, Antoine Toubert, Andrea Velardi
Journal: Blood
Blood (2015) 126 (23): 1929.
https://doi.org/10.1182/blood.V126.23.1929.1929
Published: 2015
Journal Articles

Defibrotide for Prophylaxis of Hepatic Veno-Occlusive Disease in Pediatric Hematopoietic Stem Cell Transplantation: Subanalysis Data from an Open-Label, Phase III, Randomized Trial

Selim Corbacioglu, MD, Ansgar S. Schulz, MD, Petr Sedlacek, MD PhD, Bernd Gruhn, MD, Simone Cesaro, MD, Peter Bader, MD
Journal: Blood
Blood (2015) 126 (23): 4310.
https://doi.org/10.1182/blood.V126.23.4310.4310
Published: 2015