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Maria Speranza Massei
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Journal Articles

How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation

Loredana Ruggeri, Alessandra Carotti, MD, Antonio Pierini, Franca Falzetti, Adelmo Terenzi, MD, Elena Urbani, Amico Lucia, MD PhD, Sara Tricarico, MD, Sara Piccinelli, MD, Maria Speranza Massei, MD, Sara Ciardelli, Mauro Di Ianni, MD PhD, Tiziana Zei, Roberta Iacucci Ostini, Valentina Lancellotta, MD, Simonetta Saldi, MD, Olivia Minelli, MD, Rita Tognellini, Mara Merluzzi, Mauro Marchesi, MD, Maurizio Caniglia, MD, Cynthia Aristei, MD PhD, Brunangelo Falini, MD PhD, Massimo Fabrizio Martelli, MD PhD, Andrea Velardi
Journal: Blood
Blood (2018) 132 (Supplement 1): 3333.
https://doi.org/10.1182/blood-2018-99-112512
Published: 2018
Journal Articles

Mother Donors Improve Outcomes after HLA Haploidentical Hematopoietic Transplantation: A Retrospective Study By the Cell Therapy and Immunobiology Working Party of the EBMT

Andrea Velardi, Loredana Ruggeri, Dimitris Ziagkos, Anja van Biezen, Mara Merluzzi, Attilio Bondanza, MD PhD, Nathasja Bootsman, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Maddalena Noviello, PhD, Fabio Ciceri, MD, Thomas Klingebiel, MD, Yener Koc, MD, Hendrik Veelken, MD PhD, Franco Locatelli, MD, William Arcese, Bernd Gruhn, MD, Flavia Salvi, Chiara Bonini, MD, Jon J. van Rood, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3472.
https://doi.org/10.1182/blood.V128.22.3472.3472
Published: 2016
Journal Articles

Chemotherapy-Based HLA Haploidentical Transplantation with Treg/Tcon Immunotherapy in Unfit/Elderly Leukemia Patients: Powerful Gvl Effect and Insights from Animal Models

Loredana Ruggeri, Alessandra Carotti, Franca Falzetti, MD, Mauro Diianni, Antonio Pierini, MD, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Elena Urbani, Massimo Fabrizio Martelli, Andrea Velardi
Journal: Blood
Blood (2016) 128 (22): 3483.
https://doi.org/10.1182/blood.V128.22.3483.3483
Published: 2016
Journal Articles

An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT

Attilio Bondanza, MD PhD, Loredana Ruggeri, Dimitris Ziagkos, Chiara Bonini, MD, Christian Chabannon, Natalia Bootsman, Cora Knol-Bout, Liesbeth De Wreede, Maddalena Noviello, PhD, Lara Crucitti, MD, Luca Vago, MD PhD, Alessandra Carotti, Adelmo Terenzi, Mara Merluzzi, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Joan Hendrik Veelken, Yener Koc, MD, Peter Bader, MD, Bernd Gruhn, MD, Franco Locatelli, MD PhD, Fabio Ciceri, MD, Antoine Toubert, Andrea Velardi
Journal: Blood
Blood (2015) 126 (23): 1929.
https://doi.org/10.1182/blood.V126.23.1929.1929
Published: 2015
Journal Articles

Haploidentical hematopoietic transplantation from KIR ligand–mismatched donors with activating KIRs reduces nonrelapse mortality

Clinical Trials & Observations
Antonella Mancusi, Loredana Ruggeri, Elena Urbani, Antonio Pierini, Maria Speranza Massei, Alessandra Carotti, Adelmo Terenzi, Franca Falzetti, Antonella Tosti, Fabiana Topini, Silvia Bozza, Luigina Romani, Rita Tognellini, Martin Stern, Franco Aversa, Massimo F. Martelli, Andrea Velardi
Journal: Blood
Blood (2015) 125 (20): 3173–3182.
https://doi.org/10.1182/blood-2014-09-599993
Published: 2015
Includes: Supplemental data
Journal Articles

Tregs Suppress GvHD at the Periphery and Unleash the Gvl Effect in the Bone Marrow

Loredana Ruggeri, Mauro Di Ianni, Elena Urbani, Antonella Mancusi, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Maria Speranza Massei, Lucia Amico, Tiziana Zei, Roberta Iacucci, Massimo Fabrizio Martelli, Andrea Velardi
Journal: Blood
Blood (2014) 124 (21): 842.
https://doi.org/10.1182/blood.V124.21.842.842
Published: 2014
Journal Articles

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse

Clinical Trials & Observations
Massimo F. Martelli, Mauro Di Ianni, Loredana Ruggeri, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Antonio Pierini, Maria Speranza Massei, Lucia Amico, Elena Urbani, Beatrice Del Papa, Tiziana Zei, Roberta Iacucci Ostini, Debora Cecchini, Rita Tognellini, Yair Reisner, Franco Aversa, Brunangelo Falini, Andrea Velardi
Journal: Blood
Blood (2014) 124 (4): 638–644.
https://doi.org/10.1182/blood-2014-03-564401
Published: 2014
Journal Articles

HLA-Haploidentical Stem Cell Transplantation with Treg and Tcon Adoptive Immunotherapy promotes a Strong Graft-Versus-Leukemia Effect

Mauro Di Ianni, Loredana Ruggeri, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Maria Speranza Massei, Lucia Amico, Antonio Pierini, Andrea Velardi, Massimo Fabrizio Martelli
Journal: Blood
Blood (2013) 122 (21): 907.
https://doi.org/10.1182/blood.V122.21.907.907
Published: 2013
Journal Articles

Adoptive Immunotherapy with Tregs and Tcons Ensures Low TRM and a Low Incidence of Post Transplant Leukaemia Relapse After HLA Haploidentical Transplants for Acute Leukemia

Mauro Di Ianni, Franca Falzetti, Alessandra Carotti, Adelmo Terenzi, Loredana Ruggeri, Pierini Antonio, Vincenza de Fazio, Valentina Zoi, Maria Speranza Massei, Yair Reisner, Andrea Velardi, Franco Aversa, Massimo Fabrizio Martelli, MD
Journal: Blood
Blood (2011) 118 (21): 154.
https://doi.org/10.1182/blood.V118.21.154.154
Published: 2011