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Journal Articles

Single-Cell Multiomics Reveals a Shared Mechanism of Lineage Switch in DUX4r, ZNF384r, and PAX5 P80R Subtypes of Pediatric Acute Lymphoblastic Leukemia

Vojen Sadílek, Barbora Cabalkova, Aneta Skotnicova, Michaela Reiterova, Martina Vaskova, Marketa Zaliova, Ondrej Hrusak, Jan Trka, Tomas Kalina, Eva Fronkova, Ester Mejstrikova, Jan Stuchly

Blood (2024) 144 (Supplement 1): 635.

https://doi.org/10.1182/blood-2024-209607

Published: 2024

Journal Articles

CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment

Blood (2024) 143 (17): 1738–1751.

https://doi.org/10.1182/blood.2023021952

Published: 2024

Includes: Supplemental data

Journal Articles

Superior Overall Survival with Blinatumomab Versus Chemotherapy As Pre-Transplant Consolidation Treatment in Children with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL): Longer Follow-up (FU) of a Phase 3 Randomized Controlled Trial (RCT)

Blood (2021) 138 (Supplement 1): 1231.

https://doi.org/10.1182/blood-2021-145476

Published: 2021

Journal Articles

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-142314

Published: 2020

Journal Articles

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection

Elena Varotto, MD PhD, Margarita Maurer-Granofszky, PhD, Daniela Silvestri, Pamela Scarparo, PhD, Ester Mejstrikova, MD PhD, Monika Brüggemann, Giovanni Cazzaniga, PhD, Valentino Conter, MD, Ondrej Hrusak, MD PhD, Giuseppe Gaipa, PhD, Angela Schumich, Maria Grazia Valsecchi, PhD, Giuseppe Basso, MD PhD, Michael Dworzak, MD, Barbara Buldini, MD PhD

Blood (2019) 134 (Supplement_1): 377.

https://doi.org/10.1182/blood-2019-127287

Published: 2019

Journal Articles

Deep Immunoprofiling By Flow Cytometry and NGS Reveals Distinct T Cell Profile in Pediatric Hepatitis-Associated Aplastic Anemia

Michaela Novakova, Michael Svaton, MD, Martina Sukova, MD, Veronika Kanderova, MSc, PhD, Nikos Darzentas, PhD, Lenka Kramna, MSc, PhD, Ondrej Cinek, Prof., MD PhD, Dagmar Pospisilova, Prof MD PhD, Jan Trka, Prof., MD PhD, Ondrej Hrusak, MD PhD, Jan Stary, Prof., MD PhD, Ester Mejstrikova, MD PhD, Eva Fronkova, MD PhD

Blood (2019) 134 (Supplement_1): 2508.

https://doi.org/10.1182/blood-2019-127986

Published: 2019

Journal Articles

B Cell Precursor Lymphoblastic Leukemia Patients with Good Treatment Response Have Low Levels of Erythroid Precursors

Barbora Vakrmanova, MD, Michaela Novakova, Martina Vaskova, Iveta Janotová, Elena Vodickova, MD, Monika Brüggemann, Eva Fronkova, MD PhD, Jan Trka, MD PhD, Jan Stary, MD PhD, Ondrej Hrusak, Ester Mejstrikova, MD PhD

Blood (2018) 132 (Supplement 1): 2832.

https://doi.org/10.1182/blood-2018-99-117976

Published: 2018

Journal Articles

Switching Towards Monocytic Lineage and Discordancy between Flow Cytometric and PCR Minimal Residual Disease Results Is a Hallmark Feature of DUX4 Rearranged B-Cell Precursor Acute Lymphoblastic Leukemia

Michaela Novakova, Barbora Vakrmanova, MD, Lucie Slamova, Alena Musilova, Monika Brüggemann, Matthias Ritgen, MD, Eva Fronkova, MD PhD, Tomas Kalina, MD PhD, Jan Trka, MD PhD, Jan Stary, MD PhD, Martina Vaskova, Lucie Winkowska, Marketa Zaliova, Karel Fišer, PhD, Ondrej Hrusak, Ester Mejstrikova, MD PhD

Blood (2018) 132 (Supplement 1): 2825.

https://doi.org/10.1182/blood-2018-99-116575

Published: 2018

Journal Articles

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

Blood (2018) 132 (3): 264–276.

https://doi.org/10.1182/blood-2017-12-821363

Published: 2018

Includes: Supplemental data

Journal Articles

When Standard Markers Are Not Sufficient for Monitoring Minimal Residual Disease or Targeted Treatment: New Transcriptome Derived Flow Cytometry Markers for Switching B Cell Precursor Leukemias

Michaela Novakova, Alena Musilova, Lucie Slamova, Barbora Vakrmanova, Monika Brüggemann, Matthias Ritgen, Eva Fronkova, Tomas Kalina, Ondrej Hrusak, Jan Trka, Jan Stary, Martina Vaskova, Lucie Winkowska, Marketa Zaliova, Karel Fiser, Ester Mejstrikova

Blood (2017) 130 (Supplement 1): 3982.

https://doi.org/10.1182/blood.V130.Suppl_1.3982.3982

Published: 2017

Journal Articles

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia

Blood (2017) 129 (3): 347–357.

https://doi.org/10.1182/blood-2016-07-726307

Published: 2017

Includes: Supplemental data

Journal Articles

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

Ondrej Hrusak, MD PhD, Valerie De Haas, MD PhD, Ales Luks, Iveta Janotova, Ester Mejstrikova, MD PhD, Kirsten Bleckmann, MD, Anja Moricke, MD, Julie Irving, PhD, Benigna Konatkowska, Thomas B. Alexander, MD MPH, Hiroto Inaba, MD PhD, Kjeld Schmiegelow, MD DMSc, Simone Stokley, FRCPath,, Jorge Gabriel Rossi, PhD, Maria Sara Felice, MD PhD, Luciano Dalla-Pozza, MB BS FRACP, Jessa Morales, Michael Dworzak, MD, Barbara Buldini, MD, Giuseppe Basso, Myriam Campbell, Maria Elena Cabrera, Neda Marinov, Sarah Elitzur, MD, Shai Izraeli, MD, Drorit Luria, PhD, Tamar Feuerstein, PhD, Alexandra Kolenova, MD PhD, Peter Svec, Elena Kreminska, Karen R. Rabin, MD, Sophia Polychronopoulou, MD PhD, Elaine da Costa, Hanne Vibeke Marquart, MD PhD, Antonis Kattamis, MD, Richard Ratei, Dirk Reinhardt, MD PhD, Anthony V Moorman, PhD, Martin Schrappe, MD, Jan Stary, MD D.Sc.

Blood (2016) 128 (22): 584.

https://doi.org/10.1182/blood.V128.22.584.584

Published: 2016

Journal Articles

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Thomas B. Alexander, MD MPH, Zhaohui Gu, PhD, John K Choi, MD, Mignon L. Loh, MD, John Horan, MD MPH, Barbara Buldini, MD, Giuseppe Basso, Sarah Elitzur, MD, C. Michel Zwaan, MD PhD, Valerie de Haas, MD PhD, Allen Eng Juh Yeoh, MD, Dirk Reinhardt, MD PhD, Daisuke Tomizawa, MD, PhD, Tim Lammens, Barbara De Moerloose, MD, Li Zhou, PhD, Hiroki Hori, MD PhD, Anthony V. Moorman, PhD, Andrew S. Moore, MBBS FRACP PhD, Ondrej Hrusak, MD PhD, Soheil Meshinchi, MD PhD, Etan Orgel, MD MS, Meenakshi Devidas, PhD, Stephen P. Hunger, MD, Jamie M Guidry Auvil, Malcolm A. Smith, MD PhD, Tanja M. Davidsen, PhD, Leandro C. Hermida, Patee Gesuwan, Marco A. Marra, PhD, Yussanne Ma, PhD, Andrew J. Mungall, Richard Moore, PhD, Daniela S. Gerhard, PhD, Xueyuan Cao, Lei Shi, PhD, Stanley Pounds, PhD, Hiroto Inaba, MD PhD, Charles Mullighan, MBBS, MSc, MD

Blood (2016) 128 (22): 454.

https://doi.org/10.1182/blood.V128.22.454.454

Published: 2016

Journal Articles

Distinct bilineal leukemia immunophenotypes are not genetically determined

Michaela Kotrova, Alena Musilova, Jan Stuchly, Karel Fiser, Julia Starkova, Ester Mejstrikova, Jan Stary, Jan Zuna, Ondrej Hrusak, Jan Trka, Marketa Zaliova

Blood (2016) 128 (18): 2263–2266.

https://doi.org/10.1182/blood-2016-07-725861

Published: 2016

Includes: Supplemental data

Journal Articles

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol

Blood (2015) 126 (23): 1414.

https://doi.org/10.1182/blood.V126.23.1414.1414

Published: 2015

Journal Articles

Acute Leukemias of Ambiguous Lineage; Study on 247 Pediatric Patients

Blood (2015) 126 (23): 252.

https://doi.org/10.1182/blood.V126.23.252.252

Published: 2015

Journal Articles

Childhood Hyperdiploid Acute Lymphoblastic Leukemia

Marketa Zaliova, Martina Vaskova, Lenka Hovorkova, Ondrej Hrusak, Jan Stary, Jan Zuna

Blood (2015) 126 (23): 4990.

https://doi.org/10.1182/blood.V126.23.4990.4990

Published: 2015

Journal Articles

Defect in B Cell Production Driven By GATA2 Mutation Results in Their Absolute Reduction and Mature Phenotype in Pediatric Patients

Michaela Novakova, Ales Janda, Marcin W Wlodarski, Martina Sukova, Vit Campr, Marketa Kubricanova Zaliova, Eva Fronkova, Elena Vodickova, Ondrej Zapletal, Jan Blatny, Katerina Lejhancova, Dagmar Pospisilova, Zdena Cerna, Tomas Kuhn, Zuzana Zemanova, Jan Trka, Ondrej Hrusak, Jan Stary, Ester Mejstrikova

Blood (2014) 124 (21): 2746.

https://doi.org/10.1182/blood.V124.21.2746.2746

Published: 2014

Journal Articles

Novel Flow Cytometry-Based Method Of Affinity Proteomics Revealing Expression, Post-Translational Modification and Proteolysis In Primary Childhood Acute Leukemias

Veronika Kanderova, PhD, Daniela Kuzilkova, MSc, Jan Stuchly, MSc, Weiwei Wu, MD, Anders Holm, PhD, Heidi Slåstad, MD, Karel Fiser, Ondrej Hrusak, Fridtjof Lund-Johansen, MD, PhD, Tomas Kalina, MD, PhD

Blood (2013) 122 (21): 2553.

https://doi.org/10.1182/blood.V122.21.2553.2553

Published: 2013

Journal Articles

Backtracking Of The Genetic Events Preceding Acute Leukemia Diagnosis

Olga Zimmermannova, Marketa Zaliova, Ester Mejstrikova, Eva Fronkova, Marie Jarosova, Zuzana Zemanova, Libuse Lizcova, Halima A Al-Shehhi, Anthony V. Moorman, Ajay J Vora, Claus Meyer, Rolf Marschalek, Jan Stary, Jan Trka, Ondrej Hrusak, Jan Zuna

Blood (2013) 122 (21): 2562.

https://doi.org/10.1182/blood.V122.21.2562.2562

Published: 2013

NARROW

Single-Cell Multiomics Reveals a Shared Mechanism of Lineage Switch in DUX4r, ZNF384r, and PAX5 P80R Subtypes of Pediatric Acute Lymphoblastic Leukemia

CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment

Superior Overall Survival with Blinatumomab Versus Chemotherapy As Pre-Transplant Consolidation Treatment in Children with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL): Longer Follow-up (FU) of a Phase 3 Randomized Controlled Trial (RCT)

In Vitro Drug Response Profiling in BCP- and T-ALL Primary Samples Adds a Robust Functional Layer Enabling Optimized Guidance of Individualized Therapy in Relapsed and Refractory Pediatric Acute Leukemia Patients

Transient Switch to Myeloid Lineage in Acute Lymphoblastic Leukemia during Induction Therapy: The Role of CD371 Expression and Implication for Minimal Residual Disease Detection

Deep Immunoprofiling By Flow Cytometry and NGS Reveals Distinct T Cell Profile in Pediatric Hepatitis-Associated Aplastic Anemia

B Cell Precursor Lymphoblastic Leukemia Patients with Good Treatment Response Have Low Levels of Erythroid Precursors

Switching Towards Monocytic Lineage and Discordancy between Flow Cytometric and PCR Minimal Residual Disease Results Is a Hallmark Feature of DUX4 Rearranged B-Cell Precursor Acute Lymphoblastic Leukemia

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia

When Standard Markers Are Not Sufficient for Monitoring Minimal Residual Disease or Targeted Treatment: New Transcriptome Derived Flow Cytometry Markers for Switching B Cell Precursor Leukemias

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia

Acute Leukemia of Ambiguous Lineage: A Comprehensive Survival Analysis Enables Designing New Treatment Strategies

Genomic Landscape of Pediatric Mixed Phenotype Acute Leukemia

Distinct bilineal leukemia immunophenotypes are not genetically determined

Validation of MRD Quantification By Flow Cytometry for Pediatric BCP ALL Relapsed Patients Treated on the Intreall Protocol

Acute Leukemias of Ambiguous Lineage; Study on 247 Pediatric Patients

Childhood Hyperdiploid Acute Lymphoblastic Leukemia

Defect in B Cell Production Driven By GATA2 Mutation Results in Their Absolute Reduction and Mature Phenotype in Pediatric Patients

Novel Flow Cytometry-Based Method Of Affinity Proteomics Revealing Expression, Post-Translational Modification and Proteolysis In Primary Childhood Acute Leukemias

Backtracking Of The Genetic Events Preceding Acute Leukemia Diagnosis

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American Society of Hematology

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American Society of Hematology

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