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Chiara Buracchi
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Journal Articles

CD19 CAR T Cells Drive a Remodeling of the Immune Microenvironment Associated with T-Cell Dysfunction in Acute Lymphoblastic Leukemia

Marianna Ponzo, Lorenzo Drufuca, Chiara Buracchi, Marco M Sindoni, Silvia Nucera, Cristina Bugarin, Ramona Bason, Grazisa Rossetti, Raul Bonnal, Cristian Meli, Benedetta Rambaldi, Federico Lussana, Silvia Ferrari, Alex Moretti, Giulia Risca, Christian Pellegrino, Markus G. Manz, Stefania Galimberti, Alessandro Rambaldi, Andrea Biondi, Giuseppe Gaipa, Massimiliano Pagani, Chiara F. Magnani
Journal: Blood
Blood (2024) 144 (Supplement 1): 2834.
https://doi.org/10.1182/blood-2024-206806
Published: 2024
Journal Articles

Role of Microenvironment in Influencing the Activity of CD19 CAR T Cells in B-Cell Precursor Acute Lymphoblastic Leukemia (B-ALL)

Marianna Ponzo, Lorenzo Drufuca, Chiara Buracchi, Silvia Nucera, Cristina Bugarin, Grazisa Rossetti, Raoul Bonnal, Benedetta Rambaldi, Andrea Biondi, Giuseppe Gaipa, Massimiliano Pagani, Chiara Francesca Magnani
Journal: Blood
Blood (2023) 142 (Supplement 1): 3475.
https://doi.org/10.1182/blood-2023-180608
Published: 2023
Journal Articles

First Description of a Frameshift PAX5 Germline Variant in Two Siblings with B-Cell Precursor Acute Lymphoblastic Leukemia

Laura Rachele Bettini, Grazia Fazio, Claudia Saitta, Sonia Palamini, Chiara Buracchi, Stefano Rebellato, Nicola Santoro, Cristiano Simone, Andrea Biondi, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 3489–3490.
https://doi.org/10.1182/blood-2022-169311
Published: 2022
Journal Articles

Carcik-CD19 Cells Expand In Vivo Toward a CD8 + Memory Phenotype and Their Persistence Is Associated with a Longer Duration of Response

Benedetta Rambaldi, Stefania Galimberti, Giuliana Rizzuto, Chiara Francesca Magnani, Chiara Buracchi, Giulia Risca, Martina Paredi, Daniela Belotti, Alex Moretti, Marianna Ponzo, Sarah Tettamanti, Gian Maria Borleri, Cristian Meli, Muriel Paganessi, Silvia Zaninelli, Elisa Gotti, Chiara Capelli, Martino Introna, Federico Lussana, Giuseppe Gritti, Silvia Ferrari, Anna Grassi, Sara Napolitano, Adriana Balduzzi, Maria Grazia Valsecchi, Giuseppe Dastoli, Alessandro Rambaldi, Andrea Biondi, Giuseppe Gaipa
Journal: Blood
Blood (2022) 140 (Supplement 1): 10339–10340.
https://doi.org/10.1182/blood-2022-166788
Published: 2022
Journal Articles

Final Results of Phase I/II Study of Donor-Derived CAR T Cells Engineered with Sleeping Beauty in Pediatric and Adult Patients with B-Cell Acute Lymphoblastic Leukemia Relapsed Post-HSCT

Federico Lussana, Chiara Francesca Magnani, Giuseppe Gaipa, Stefania Galimberti, Giuseppe Gritti, Daniela Belotti, Sara Napolitano, Chiara Buracchi, Gian Maria Borleri, Benedetta Rambaldi, Giuliana Rizzuto, Anna Grassi, Muriel Paganessi, Silvia Ferrari, Sarah Tettamanti, Giovanni Gazzaniga, Chiara Capelli, Elisa Gotti, Martino Introna, Adriana Balduzzi, Maria Grazia Valsecchi, Giuseppe Dastoli, Alessandro Rambaldi, Andrea Biondi
Journal: Blood
Blood (2022) 140 (Supplement 1): 4568–4569.
https://doi.org/10.1182/blood-2022-165448
Published: 2022
Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty in Pediatric and Adult Patients with Acute Lymphoblastic Leukemia Relapsed Post-HSCT

Chiara F Magnani, Giuseppe Gaipa, Federico Lussana, Giuseppe Gritti, Daniela Belotti, Sara Napolitano, Chiara Buracchi, Gian Maria Borleri, Benedetta Rambaldi, Silvia Zaninelli, Giuliana Rizzuto, Gianluca Cavallaro, Sarah Tettamanti, Giovanni Cazzaniga, Stefania Galimberti, Silvia Ferrari, Martino Introna, Adriana Balduzzi, Maria Grazia Valsecchi, Giuseppe Dastoli, Alessandro Rambaldi, Andrea Biondi
Journal: Blood
Blood (2021) 138 (Supplement 1): 472.
https://doi.org/10.1182/blood-2021-148703
Published: 2021
Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity

Chiara F Magnani, Giuseppe Gaipa, PhD, Federico Lussana, MD, Daniela Belotti, Giuseppe Gritti, MD PhD, Sara Napolitano, MD, Chiara Buracchi, PhD, Gian Maria Borleri, Silvia Zaninelli, Giuliana Rizzuto, Sarah Tettamanti, PhD, Valentina Colombo, Giovanni Cazzaniga, PhD, Benedetta Cabiati, Attilio Rovelli, MD, Ettore Biagi, MD PhD, Stefania Galimberti, PhD, Fabrizio Benedicenti, Eugenio Montini, PhD, Silvia Ferrari, MD, Martino Introna, MD, Adriana Balduzzi, MD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Alessandro Rambaldi, MD, Andrea Biondi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141236
Published: 2020
Journal Articles

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Chiara F Magnani, PhD, Giuseppe Gaipa, PhD, Daniela Belotti, Giada Matera, Sarah Tettamanti, PhD, Benedetta Cabiati, Chiara Buracchi, PhD, Grazia Fazio, Silvia Zaninelli, Silvia Rigamonti, Stefania Cesana, Valentina Colombo, Giovanni Cazzaniga, PhD, Attilio Rovelli, MD, Adriana Balduzzi, MD, Sara Napolitano, MD, Fabrizio Benedicenti, Eugenio Montini, PhD, Gian Maria Borleri, Silvia Ferrari, MD, Giuseppe Gritti, MD PhD, Federico Lussana, MD, Martino Introna, MD, Alessandro Rambaldi, MD, Giuseppe Dastoli, MD, Andrea Biondi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 200.
https://doi.org/10.1182/blood-2019-125894
Published: 2019
Journal Articles

Preclinical Assessment of Non-Virally Engineered CD33.CAR Cytokine-Induced Killer (CIK) Cells in Chemoresistant AML Patient-Derived Xenografts

Maria Caterina Rotiroti, PhD, Chiara Buracchi, PhD, Silvia Arcangeli, PhD, Chiara F Magnani, PhD, Claudia Cappuzzello, PhD, Zsuzsanna Izsvak, PhD, Stefania Galimberti, PhD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Marta Serafini, PhD, Ettore Biagi, MD, Andrea Biondi, MD, Sarah Tettamanti, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2665.
https://doi.org/10.1182/blood-2019-130399
Published: 2019
Journal Articles

Targeting a Specific Glycosylated Epitope of CD43 with a New Humanized Monoclonal Antibody for the Treatment of Pediatric and Adult T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Cirino Botta, MD, Giuseppe Gaipa, PhD, Maria Eugenia Gallo Cantafio, PhD, Chiara Buracchi, PhD, Maria Anna Siciliano, MD, Caterina Riillo, MD, Katia Grillone, PhD, Alessandro Gulino, Maria Cucè, Nicoletta Staropoli, Andrea Ghelli Luserna Di Rora, Franca Maria Tuccillo, Maria Teresa Di Martino, Claudio Tripodo, MD, Marco Rossi, MD, Giovanni Martinelli, Andrea Biondi, MD, Pierosandro Tagliaferri, Pierfrancesco Tassone, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1418.
https://doi.org/10.1182/blood-2018-99-118572
Published: 2018
Journal Articles

Specific Targeting of Acute Myeloid Leukemia By the Use of Non-Virally Engineered CIK (Cytokine-Induced Killer) Cells Expressing the Anti-CD33 Chimeric Antigen Receptor (CAR)

Maria Caterina Rotiroti, MSc, Silvia Arcangeli, PhD, Chiara Buracchi, PhD, Chiara Francesca Magnani, PhD, Claudia Cappuzzello, PhD, Ettore Biagi, MD, Sarah Tettamanti, PhD, Andrea Biondi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2201.
https://doi.org/10.1182/blood-2018-99-114572
Published: 2018
Journal Articles

Clinical-Grade Transduction of Allogeneic Cytokine Induced Killer (CIK) Cells with CD19 Chimeric Antigen Receptor (CAR) Using Sleeping Beauty (SB) Transposon: Successful GMP-Compliant Manufacturing for Clinical Applications

Giuseppe Gaipa, PhD, Chiara Francesca Magnani, PhD, Daniela Belotti, Giada Matera, Sarah Tettamanti, PhD, Benedetta Cabiati, Stefania Cesana, Valentina Colombo, Giovanni Cazzaniga, PhD, Grazia Fazio, PhD, Chiara Buracchi, PhD, Silvia Rigamonti, Attilio Rovelli, MD, Adriana Balduzzi, MD, Sara Napolitano, MD, Eugenio Montini, Gian Maria Borleri, Giuseppe Gritti, MD PhD, Federico Lussana, MD PhD, Martino Introna, MD, Alessandro Rambaldi, MD, Giuseppe Dastoli, MD, Andrea Biondi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 196.
https://doi.org/10.1182/blood-2018-196
Published: 2018
Journal Articles

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia

Prisca Theunissen, Ester Mejstrikova, Lukasz Sedek, Alita J. van der Sluijs-Gelling, Giuseppe Gaipa, Marius Bartels, Elaine Sobral da Costa, Michaela Kotrová, Michaela Novakova, Edwin Sonneveld, Chiara Buracchi, Paola Bonaccorso, Elen Oliveira, Jeroen G. te Marvelde, Tomasz Szczepanski, Ludovic Lhermitte, Ondrej Hrusak, Quentin Lecrevisse, Georgiana Emilia Grigore, Eva Froňková, Jan Trka, Monika Brüggemann, Alberto Orfao, Jacques J. M. van Dongen, Vincent H. J. van der Velden
Journal: Blood
Blood (2017) 129 (3): 347–357.
https://doi.org/10.1182/blood-2016-07-726307
Published: 2017
Includes: Supplemental data
Journal Articles

Euroflow-Based Immunophenotypic Characterization of CD34+ Cell Compartment in Juvenile Myelomonocytic Leukemia (JMML): A New Tool for Differential Diagnosis

Giuseppe Gaipa, PhD, Cristina Bugarin, Sergio Matarraz, Chiara Buracchi, PhD, Lukasz Sedek, MDPhD, Vincent H.J. van der Velden, PhD, Tomasz Szczepanski, Prof MD PhD, Alita van der Sluijs, Elaine Sobral da Costa, Michaela Novakova, Ester Mejstrikova, MD PhD, Carmen Aanei, Jacques JM van Dongen, Andrea Biondi, MD, Alberto Orfao, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3127.
https://doi.org/10.1182/blood.V128.22.3127.3127
Published: 2016
Journal Articles

Mass Cytometry Analysis Dissects CRLF2-Driven Signaling Pathways in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL)

Jolanda Sarno, Kara L. Davis, DO, Angela Maria Savino, PhD, Cristina Bugarin, Stefania Pinto, Chiara Buracchi, PhD, Astraea Jager, BS, Chiara Palmi, PhD, Ruth C Barber, PhD, Daniela Silvestri, Gianni Cazzaniga, PhD, Martin J.S. Dyer, Prof., Andrea Biondi, Prof, MD, Garry P. Nolan, Prof, PhD, Giuseppe Gaipa, PhD
Journal: Blood
Blood (2015) 126 (23): 906.
https://doi.org/10.1182/blood.V126.23.906.906
Published: 2015
Journal Articles

Loss of PTEN in Pediatric T-Cell Acute Lymphoblastic Leukemia Patients: Proteomic and Molecular Characterization

Paola Bonaccorso, Cristina Bugarin, Chiara Buracchi, Grazia Fazio, Maddalena Paganin, Giuseppe Basso, Andrea Biondi, Giovanni Cazzaniga, Luca Lo Nigro, Giuseppe Gaipa
Journal: Blood
Blood (2014) 124 (21): 2408.
https://doi.org/10.1182/blood.V124.21.2408.2408
Published: 2014
Journal Articles

Control of murine Ly6C high monocyte traffic and immunosuppressive activities by atypical chemokine receptor D6

Benedetta Savino, Marina G. Castor, Nicoletta Caronni, Adelaida Sarukhan, Achille Anselmo, Chiara Buracchi, Federica Benvenuti, Vanessa Pinho, Mauro M. Teixeira, Alberto Mantovani, Massimo Locati, Raffaella Bonecchi
Journal: Blood
Blood (2012) 119 (22): 5250–5260.
https://doi.org/10.1182/blood-2011-10-388082
Published: 2012
Includes: Supplemental data