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Journal Articles

Somatic and Germline Cohesin Genes Alterations in Pediatric Acute Lymphoblastic Leukemia

Stefano Rebellato, Claudia Saitta, Laura Rachele Bettini, Daniela Silvestri, Orietta Spinelli, Agata Pastorczak, Danielle Brandes, Ute Fischer, Arndt Borkhardt, Sabine Strehl, Luca Lo Nigro, Barbara Buldini, Julia Hauer, Franziska Auer, Lennart Kester, Roland P. Kuiper, Luciana Vinti, Franco Locatelli, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga
Journal: Blood
Blood (2023) 142 (Supplement 1): 1600.
https://doi.org/10.1182/blood-2023-189244
Published: 2023
Journal Articles

First Description of a Frameshift PAX5 Germline Variant in Two Siblings with B-Cell Precursor Acute Lymphoblastic Leukemia

Laura Rachele Bettini, Grazia Fazio, Claudia Saitta, Sonia Palamini, Chiara Buracchi, Stefano Rebellato, Nicola Santoro, Cristiano Simone, Andrea Biondi, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 3489–3490.
https://doi.org/10.1182/blood-2022-169311
Published: 2022
Journal Articles

Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia

Manuel Quadri, Claudia Saitta, Sonia Palamini, Chiara Palmi, Jia-Wey Tu, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga, Grazia Fazio
Journal: Blood
Blood (2022) 140 (Supplement 1): 364–365.
https://doi.org/10.1182/blood-2022-169437
Published: 2022
Journal Articles

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Chiara Palmi, Silvia Bresolin, Stefanie V. Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Claudia Saitta, Marta Galbiati, Michela Bardini, Sanil Bhatia, Arndt Borkhardt, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruij Te Kronnie, Gunnar Cario, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 6367–6368.
https://doi.org/10.1182/blood-2022-169131
Published: 2022
Journal Articles

Clinical relevance of clonal hematopoiesis in persons aged ≥80 years

Clinical Trials & Observations
Marianna Rossi, Manja Meggendorfer, Matteo Zampini, Mauro Tettamanti, Emma Riva, Erica Travaglino, Matteo Bersanelli, Sara Mandelli, Alessia Antonella Galbussera, Ettore Mosca, Elena Saba, Chiara Chiereghin, Nicla Manes, Chiara Milanesi, Marta Ubezio, Lucio Morabito, Clelia Peano, Giulia Soldà, Rosanna Asselta, Stefano Duga, Carlo Selmi, Maria De Santis, Karolina Malik, Giulia Maggioni, Marilena Bicchieri, Alessia Campagna, Cristina A. Tentori, Antonio Russo, Efrem Civilini, Paola Allavena, Rocco Piazza, Giovanni Corrao, Claudia Sala, Alberto Termanini, Laura Giordano, Paolo Detoma, Aurelio Malabaila, Luca Sala, Stefano Rosso, Roberto Zanetti, Claudia Saitta, Elena Riva, Gianluigi Condorelli, Francesco Passamonti, Armando Santoro, Francesc Sole, Uwe Platzbecker, Pierre Fenaux, Niccolò Bolli, Gastone Castellani, Wolfgang Kern, George S. Vassiliou, Torsten Haferlach, Ugo Lucca, Matteo G. Della Porta
Journal: Blood
Blood (2021) 138 (21): 2093–2105.
https://doi.org/10.1182/blood.2021011320
Published: 2021
Includes: Supplemental data
Journal Articles

Potential Role of STAG1 Mutations in Genetic Predisposition to Childhood Hemato-Oncological Diseases

Claudia Saitta, Stefano Rebellato, Laura Rachele Bettini, Giovanni Giudici, Nicolò Panini, Eugenio Erba, Simona Songia, Valentina Massa, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga
Journal: Blood
Blood (2021) 138 (Supplement 1): 1155.
https://doi.org/10.1182/blood-2021-152586
Published: 2021
Journal Articles

Recurrent Germline Variant in the Cohesin Complex Gene RAD21 Predisposes Children to Lymphoblastic Leukemia and Lymphoma

Anne Schedel, Ulrike Anne Friedrich, Rabea Wagener, Juha Mehtonen, Claudia Saitta, Triantafyllia Brozou, Pia Michler, Carolin Walter, Peter Horak, Nagarajan Paramasivam, Grazia Fazio, Stefan Fröhling, Martin Dugas, Daniela Richter, Hanno Glimm, Merja Heinäniemi, Rolf Jessberger, Giovanni Cazzaniga, Arndt Borkhardt, Julia Hauer, Franziska Auer
Journal: Blood
Blood (2021) 138 (Supplement 1): 3358.
https://doi.org/10.1182/blood-2021-150284
Published: 2021
Journal Articles

Targeting JAK2 Gene Rearrangements with a Novel Kinase Inhibitor in a Preclinical Model of Pediatric Acute Lymphoblastic Leukemia

Manuel Quadri, Claudia Saitta, Sonia Palamini, Chiara Palmi, Andrea Biondi, Giovanni Cazzaniga, Grazia Fazio
Journal: Blood
Blood (2021) 138 (Supplement 1): 1180.
https://doi.org/10.1182/blood-2021-152270
Published: 2021
Journal Articles

Incidence and Therapeutic Implications of Germline TP53 Mutations in Hypodiploid Childhood Acute Lymphoblastic Leukemia: A Retrospective Analysis of the Italian Cohort

Laura Rachele Bettini, Claudia Saitta, Barbara Buldini, Geertruij Te Kronnie, Stefano Rebellato, Daniela Silvestri, Elena Barisone, Andrea Pession, Marco Rabusin, Concetta Micalizzi, Franco Locatelli, MD PhD, Carmelo Rizzari, Maria Grazia Valsecchi, PhD, Andrea Biondi, MD, Grazia Fazio, Giovanni Cazzaniga, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43–44.
https://doi.org/10.1182/blood-2020-142729
Published: 2020
Journal Articles

Pre-Clinical Efficacy of the Novel Kinase Inhibitor Nintedanib on PAX5 Fusion Genes in Pediatric Ph-like B-Cell Precursor Acute Lymphoblastic Leukemia

Grazia Fazio, Silvia Bresolin, Claudia Saitta, Daniela Silvestri, Elena Vendramini, Chiara Palmi, Silvia Rigamonti, Marta Galbiati, Manuel Quadri, Stefano Mecca, Angela Maria Savino, Michela Bardini, Andrea Grioni, Maria Grazia Valsecchi, PhD, Geertruy te Kronnie, Andrea Biondi, MD, Giovanni Cazzaniga, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 745.
https://doi.org/10.1182/blood-2019-128509
Published: 2019