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Sanil Bhatia
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Journal Articles

Overcoming Stress Response-Induced Drug Resistance through Targeting CDK9 in Ph+ Leukemia

Melina Vogt, Marie Kemkes, Berna-Selin Bilen, Julian Schliehe-Diecks, Katerina Scharov, Jia-Wey Tu, Ute Fischer, Aleksandra A. Pandyra, Arndt Borkhardt, Sanil Bhatia
Journal: Blood
Blood (2024) 144 (Supplement 1): 5823.
https://doi.org/10.1182/blood-2024-198438
Published: 2024
Journal Articles

Immune Training Enhances Anti-Viral Responses and Improves Outcomes in Pax5 -/+ Mice Susceptible to Chronic Infection

Zhe Lu, Olivia Stencel, Wei Liu, Eleni Vasileiou, Haifeng Chris Xu, Piyush Pandey, Pawel Stachura, Abdelrahman Elwy, Anastassia Tsombal, Ann-Sophie Mai, Auer Franziska, Mina Morcos, Maximilian Seidl, Sarah Elitzur, Gunther Hartmann, Karl Sebastian Lang, Stefan Janssen, Sanil Bhatia, Philipp Lang, Ute Fischer, Julia Hauer, Arndt Borkhardt, Aleksandra A. Pandyra
Journal: Blood
Blood (2024) 144 (Supplement 1): 1160.
https://doi.org/10.1182/blood-2024-194227
Published: 2024
Journal Articles

Biallelic PI4KA mutations Disrupt B Cell Mitochondrial Metabolism and Cause Hypogammaglobulinemia

Francesco Saettini, Fabiola Guerra, Mario Mauri, Grazia Fazio, Cristina Bugarin, Manuel Quadri, Stefano Rebellato, Clizia Chinello, Lisa Pagani, Federica Malighetti, Luis González Gutiérrez-Solana, Vanna Denti, Fatemeh Emam Mousavi, Miquell Raspall-Chaure, Martin-Nalda Andrea, Estibaliz Barredo, David Adams, O'Leary Melanie, Precilla D'Souza, Ellen Macnamara, Sergio Rosenzweig, Hye Sun Kuehn, Jennifer Stoddard, Heather C Mefford, Giorgia Mandrile, Lisa Pavinato, Alfredo Brusco, Patricia Valentina Velez Santamaria, Aurora Pujol, Vincent Michaud, Agathe Roubertie, Zoe Nelson, Margaret P Adam, Bernice Lo, Holm Uhlig, Claire G Salter, Emma Baple, Andrew H Crosby, Sanil Bhatia, Fulvio Magni, Giuseppe Paglia, Giovanni Cazzaniga, Rocco Piazza, Andrea Biondi, Matteo Barberis
Journal: Blood
Blood (2023) 142 (Supplement 1): 153.
https://doi.org/10.1182/blood-2023-185551
Published: 2023
Journal Articles

CNS Invasion of TCF3::PBX1 + Leukemia Cells Requires Upregulation of AP-1 Signaling As Revealed By Brain Organoid Model

Philip Gebing, Stefanos Loizou, Sebastian Hänsch, Julian Schliehe-Diecks, Lea Spory, Pawel Stachura, Aleksandra Pandyra, Martin Schrappe, Gunnar Cario, Ameera Alsadeq, Denis Martin Schewe, Arndt Borkhardt, Lennart Lenk, Ute Fischer, Sanil Bhatia
Journal: Blood
Blood (2023) 142 (Supplement 1): 1407.
https://doi.org/10.1182/blood-2023-178613
Published: 2023
Journal Articles

The RNA Binding Protein Musashi-2 (MSI2) Sustains the Growth and the Leukemogenic Potential of MLL-Rearranged Acute Lymphoblastic Leukemia, and It Is Involved in Glucocorticoid Resistance

Luigia Valsecchi, Simone Naso, Simona Procopio, Mario Mauri, Rocco Piazza, Titus Watrin, Sanil Bhatia, Valentina Pasquale, Elena Sacco, Chiara Palmi, Grazia Fazio, Luca Trentin, Silvia Bresolin, Andrea Biondi, Giovanni Cazzaniga, Michela Bardini
Journal: Blood
Blood (2022) 140 (Supplement 1): 8827–8828.
https://doi.org/10.1182/blood-2022-166313
Published: 2022
Journal Articles

Targeting Hyperactivated Lck in PAX5 Rearranged Pediatric B-Cell Precursors Acute Lymphoblastic Leukemia

Grazia Fazio, Manuel Quadri, Silvia Bresolin, Chiara Palmi, Michela Bardini, Athanasios Oikonomou, Jia-Wey Tu, Katerina Scharov, Alberto Peloso, Titus Watrin, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 3107–3108.
https://doi.org/10.1182/blood-2022-169023
Published: 2022
Journal Articles

Novel Drugs to Target JAK2 Rearrangements in Pediatric Acute Lymphoblastic Leukemia

Manuel Quadri, Claudia Saitta, Sonia Palamini, Chiara Palmi, Jia-Wey Tu, Sanil Bhatia, Arndt Borkhardt, Andrea Biondi, Giovanni Cazzaniga, Grazia Fazio
Journal: Blood
Blood (2022) 140 (Supplement 1): 364–365.
https://doi.org/10.1182/blood-2022-169437
Published: 2022
Journal Articles

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Chiara Palmi, Silvia Bresolin, Stefanie V. Junk, Grazia Fazio, Daniela Silvestri, Marketa Zaliova, Athanasios Oikonomou, Katerina Scharov, Martin Stanulla, Anja Moericke, Martin Zimmermann, Martin Schrappe, Barbara Buldini, Claudia Saitta, Marta Galbiati, Michela Bardini, Sanil Bhatia, Arndt Borkhardt, Luca Lo Nigro, Valentino Conter, Maria Grazia Valsecchi, Andrea Biondi, Geertruij Te Kronnie, Gunnar Cario, Giovanni Cazzaniga
Journal: Blood
Blood (2022) 140 (Supplement 1): 6367–6368.
https://doi.org/10.1182/blood-2022-169131
Published: 2022
Journal Articles

An intact gut microbiome protects genetically predisposed mice against leukemia

Carolina Vicente-Dueñas, Stefan Janssen, Marina Oldenburg, Franziska Auer, Inés González-Herrero, Ana Casado-García, Marta Isidro-Hernández, Javier Raboso-Gallego, Philipp Westhoff, Aleksandra A. Pandyra, Daniel Hein, Katharina L. Gössling, Diego Alonso-López, Javier De Las Rivas, Sanil Bhatia, Francisco Javier García-Criado, María Begoña García-Cenador, Andreas P. M. Weber, Karl Köhrer, Julia Hauer, Ute Fischer, Isidro Sánchez-García, Arndt Borkhardt
Journal: Blood
Blood (2020) 136 (18): 2003–2017.
https://doi.org/10.1182/blood.2019004381
Published: 2020
Includes: Supplemental data
Journal Articles

Therapeutic Stratification of PTEN-MYC Axis Appears to be Promising for Molecular Targeted Therapies in Refractory and Relapsed T-Cell Acute Lymphoblastic Leukemia

Heinz Ahlert, MSc, BSc, Sanil Bhatia, PhD, Marc Remke, MD, Melf Sönnichsen, M.Sc., Niklas Dienstbier, M.Sc., Ute Fischer, PhD, Julia Hauer, MD, Arndt Borkhardt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3883.
https://doi.org/10.1182/blood-2019-128136
Published: 2019
Journal Articles

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

Lisa Maria Kuhn, Cyrill Schipp, PhD, Daniel Hein, PhD, Bianca Killing, Nan Qin, PhD, Vera H Jepsen, M.Sc., Heinz Ahlert, MSc, BSc, Jasmin Bartl, PhD, Viktoria Marquardt, M.Sc., David Pauck, Kai Völtzke, M.Sc., Jonathan Lim, PhD, Gabriel Leprivier, PhD, Marc Remke, MD, Sanil Bhatia, PhD, Thorsten Rosenbaum, MD, Arndt Borkhardt, MD, Ute Fischer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4651.
https://doi.org/10.1182/blood-2019-131406
Published: 2019
Journal Articles

Therapeutic Targeting of HSP90 in AML and ALL

Sanil Bhatia, PhD, Heinz Ahlert, Msc, Benedikt Frieg, PhD, Arndt Borkhardt, MD, Holger Gohlke, PhD, Thomas Kurz, Julia Hauer, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4680.
https://doi.org/10.1182/blood-2018-99-120362
Published: 2018
Journal Articles

Targeting HSP90 dimerization via the C terminus is effective in imatinib-resistant CML and lacks the heat shock response

Sanil Bhatia, Daniela Diedrich, Benedikt Frieg, Heinz Ahlert, Stefan Stein, Bertan Bopp, Franziska Lang, Tao Zang, Tobias Kröger, Thomas Ernst, Gesine Kögler, Andreas Krieg, Steffen Lüdeke, Hana Kunkel, Ana J. Rodrigues Moita, Matthias U. Kassack, Viktoria Marquardt, Friederike V. Opitz, Marina Oldenburg, Marc Remke, Florian Babor, Manuel Grez, Andreas Hochhaus, Arndt Borkhardt, Georg Groth, Luitgard Nagel-Steger, Joachim Jose, Thomas Kurz, Holger Gohlke, Finn K. Hansen, Julia Hauer
Journal: Blood
Blood (2018) 132 (3): 307–320.
https://doi.org/10.1182/blood-2017-10-810986
Published: 2018
Includes: Supplemental data
Journal Articles

Development of Novel Proteasome-HDAC6 Hybrid Inhibitors for Resistant ALL Phenotype

Sanil Bhatia, PhD, Nina Ressing, Alexandra Herrlich, Arndt Borkhardt, Prof MD, Finn Hansen, JProf. Dr., Julia Hauer, Prof. Dr.
Journal: Blood
Blood (2017) 130 (Supplement 1): 2070.
https://doi.org/10.1182/blood.V130.Suppl_1.2070.2070
Published: 2017
Journal Articles

A New ETV6-RUNX1 In Vivo Model Produces a Phenocopy of the Human Pb-ALL

Guillermo rodriguez-Hernandez, Julia Hauer, MD, Alberto Martín-Lorenzo, Daniel Schaefer, Christoph Bartenhagen, Idoia Garcia-Ramirez, Franziska Auer, Ines Gonzalez-Herrero, Lucia Ruiz-Roca, Vera Okpanyi, Ute Fischer, PhD, Martin Dugas, Sanil Bhatia, Michael Gombert, PhD, Pina Krell, Cai Chen, Marta Garcia Suquia, Maria Rascon Trincado, Angel Garcia Sanchez, Oscar Blanco, Maria garcia Cenador, Francisco Garcia-criado, Cesar Cobaleda, Diego Alonso-Lopez, Javier de Las Rivas, Carolina vicente-Duenas, Isidro Sanchez-Gracia, Arndt Borkhardt, MD
Journal: Blood
Blood (2015) 126 (23): 3658.
https://doi.org/10.1182/blood.V126.23.3658.3658
Published: 2015