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Journal Articles

A Human iPSC Model Reveals Specific Upregulation of Linker Histone H1-0 in ETV6::RUNX1 + Preleukemia and B Cell Precursor Acute Lymphoblastic Leukemia

Vera H Jepsen, Daniel Hein, Daniel Picard, Tobias Lautwein, Rabea Wagener, Nan Qin, Annika Filip, Merja Heinäniemi, Arndt Borkhardt, Ute Fischer
Journal: Blood
Blood (2022) 140 (Supplement 1): 3469–3470.
https://doi.org/10.1182/blood-2022-163564
Published: 2022
Journal Articles

An intact gut microbiome protects genetically predisposed mice against leukemia

Carolina Vicente-Dueñas, Stefan Janssen, Marina Oldenburg, Franziska Auer, Inés González-Herrero, Ana Casado-García, Marta Isidro-Hernández, Javier Raboso-Gallego, Philipp Westhoff, Aleksandra A. Pandyra, Daniel Hein, Katharina L. Gössling, Diego Alonso-López, Javier De Las Rivas, Sanil Bhatia, Francisco Javier García-Criado, María Begoña García-Cenador, Andreas P. M. Weber, Karl Köhrer, Julia Hauer, Ute Fischer, Isidro Sánchez-García, Arndt Borkhardt
Journal: Blood
Blood (2020) 136 (18): 2003–2017.
https://doi.org/10.1182/blood.2019004381
Published: 2020
Includes: Supplemental data
Journal Articles

Investigation of New Therapeutic Compounds for Juvenile Myelomonocytic Leukemia Using Induced Pluripotent Stem Cells with Stably Activated Ras Pathway

Lisa Maria Kuhn, Cyrill Schipp, PhD, Daniel Hein, PhD, Bianca Killing, Nan Qin, PhD, Vera H Jepsen, M.Sc., Heinz Ahlert, MSc, BSc, Jasmin Bartl, PhD, Viktoria Marquardt, M.Sc., David Pauck, Kai Völtzke, M.Sc., Jonathan Lim, PhD, Gabriel Leprivier, PhD, Marc Remke, MD, Sanil Bhatia, PhD, Thorsten Rosenbaum, MD, Arndt Borkhardt, MD, Ute Fischer, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4651.
https://doi.org/10.1182/blood-2019-131406
Published: 2019
Journal Articles

The preleukemic TCF3 -PBX1 gene fusion can be generated in utero and is present in ≈0.6% of healthy newborns

Daniel Hein, Karin Dreisig, Markus Metzler, Shai Izraeli, Kjeld Schmiegelow, Arndt Borkhardt, Ute Fischer
Journal: Blood
Blood (2019) 134 (16): 1355–1358.
https://doi.org/10.1182/blood.2019002215
Published: 2019
Includes: Supplemental data
Journal Articles

Determination of the Origin of the t(1;19) TCF3-PBX1 Fusion By Genomic Inverse PCR for Exploration of Ligated Breakpoints (GIPFEL)

Daniel Hein, PhD, Karin Dreisig, PhD, Shai Izraeli, MD, Kjeld Schmiegelow, MD, Arndt Borkhardt, MD, Ute Fischer, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4093.
https://doi.org/10.1182/blood-2018-99-110521
Published: 2018