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Journal Articles

Cerebrospinal Fluid Flow Cytometry Improves Patient Stratification in Central Nervous System Acute Lymphoblastic Leukaemia but Requires Careful Standardization: Results from the ALLTogether1 CSF-FLOW Sub-Study

Blood (2024) 144 (Supplement 1): 2831.

https://doi.org/10.1182/blood-2024-203138

Published: 2024

Journal Articles

Diagnosing and Staging Central Nervous System Involvement in Pediatric ALL: A Global Survey on Its Heterogeneity

Laura Almási, Cornelia Eckert, Maria Thastrup, Vera Münch, Dániel Maszárovics, Bernadett Hon-Balla, Lennart Lenk, Gábor Barna, Wenyu Yang, Mignon L. Loh, Hyoung Jin Kang, Sophia Polychronopoulou, Arja Harila, Marko Kavcic, Kjeld Schmiegelow, Lüder Hinrich Meyer, Christina Halsey, Daniel J Erdelyi

Blood (2024) 144 (Supplement 1): 2805.

https://doi.org/10.1182/blood-2024-201255

Published: 2024

Journal Articles

Allopurinol Add-on Treatment - Promising Approach to Opitimize Maintenance Therapy for Acute Lymphoblastic Leukemia in Children

Jonatan Källström, Riitta Niinimäki, Johan Fredlund, Hartmut Vogt, Laura Korhonen, Anders Castor, Kjeld Schmiegelow, Maria Thastrup, Jonas Abrahamsson, Torben Ek

Blood (2024) 144 (Supplement 1): 2809.

https://doi.org/10.1182/blood-2024-193127

Published: 2024

Journal Articles

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Pablo Peña-Martínez, Ludvig Sjöström, Helena Ågerstam, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Jan Pronk, Kjeld Schmiegelow, Axel Hyrenius-Wittsten, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2024) 144 (13): 1399–1411.

https://doi.org/10.1182/blood.2023021705

Published: 2024

Includes: Supplemental data

Journal Articles

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Sarah Elitzur, Ruth Shiloh, Jan L. C. Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Thomas Lehrnbecher, Sarah K. Tasian, Oussama Abla, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Nicole Bodmer, Triantafyllia Brozou, Francesco Ceppi, Liliia Chugaeva, Luciano Dalla Pozza, Stephane Ducassou, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Stefanie Junk, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Nizar Mahlaoui, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Marion Strullu, Thai Hoa Tran, Marek Ussowicz, Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, A. Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Veronique Minard-Colin, Kjeld Schmiegelow, Ronit Nirel, Andishe Attarbaschi, Arndt Borkhardt

Blood (2024) 144 (11): 1193–1205.

https://doi.org/10.1182/blood.2024024283

Published: 2024

Includes: Supplemental data

Journal Articles

Mapping Chemo-Resistance Profiles of Pediatric Acute Leukemia through Integration of Ex-Vivo Drug Screens with Molecular Data

Anna Pia Enblad, Olga Krali, Kristin Blom, Claes Andersson, Britt-Marie Frost, Josefine Palle, Arja Harila, Erik Forestier, Jukka Kanerva, Trond Flægstad, Ólafur G Jónsson, Kjeld Schmiegelow, Mats Heyman, Peter Nygren, Rolf Larsson, Gudmar Lönnerholm, Jessica Nordlund

Blood (2023) 142 (Supplement 1): 1449.

https://doi.org/10.1182/blood-2023-180693

Published: 2023

Journal Articles

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Ludvig Sjöström, Helena Ågerstam, Pablo Enrique Peña-Martínez, Carl Sandén, Marianne Rissler, Anders Castor, Hanne Vibeke Marquart, Signe Modvig, Kajsa Paulsson, Cornelis Pronk, Kjeld Schmiegelow, Axel Hyrenius Wittsten, Christina Orsmark-Pietras, Henrik PhD Lilljebjörn, Thoas Fioretos

Blood (2023) 142 (Supplement 1): 842.

https://doi.org/10.1182/blood-2023-173350

Published: 2023

Journal Articles

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Shunsuke Kimura, Petri Pölönen, Lindsey Montefiori, Kenneth Caldwell, Ilaria Iacobucci, Chelsey Chen, Anthony Brown, Katie Han, Yen-Chun Liu, Yunchao Chang, Zhongshan Cheng, Zhou Yinmei, Chun Shik Park, Sharnise Mitchell, Noemi Reyes, Allen Yeoh, Andishe Attarbaschi, Andrew Moore, Atsushi Manabe, Barbara Buldini, Kean Hui Chiew, Chi Kong Li, Ching-Hon Pui, Chunxu Qu, Daisuke Tomizawa, Elisabeth Paietta, Franco Locatelli, Gabriele Escherich, Gao Qingsong, Hannah Elisa Muhle, Hanne Vibeke Marquart, Hester A. de Groot-Kruseman, Jacob M. Rowe, Jan Stary, Jan Trka, John Kim Choi, Jules P.P. Meijerink, Junko Takita, Katarzyna Pawinska-Wasikowska, Kjeld Schmiegelow, Mariko Eguchi, Martin Schrappe, Martin Zimmermann, Masatoshi Takagi, Melissa Maybury, Michael Svaton, Michaela Reiterova, Michal Kicinski, Motohiro Kato, Orietta Spinelli, Pauline Mazilier, Paul G. Thomas, Riccardo Masetti, Rishi Sury Kotecha, Rob Pieters, Sarah Elitzur, Selina M Luger, Shuhong Shen, Sima Jeha, Steven M. Kornblau, Szymon Skoczen, Takako Miyamura, Tiffaney Vincent, Toshihiko Imamura, Valentino Conter, Yanjing Tang, Zhaohui Gu, Kathryn G. Roberts, David T. Teachey, Kristine R Crews, Cheng Cheng, Jun J. Yang, Hiroto Inaba, Charles G. Mullighan

Blood (2023) 142 (Supplement 1): 845.

https://doi.org/10.1182/blood-2023-178688

Published: 2023

Journal Articles

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Blood (2023) 142 (Supplement 1): 4350.

https://doi.org/10.1182/blood-2023-179306

Published: 2023

Journal Articles

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Sarah Elitzur, Ruth Shiloh, Jan Loeffen, Agata Pastorczak, Masatoshi Takagi, Simon Bomken, Andre Baruchel, Stephane Ducassou, Nizar Mahlaoui, Marion Strullu, Thomas Lehrnbecher, Kjeld Schmiegelow, Oussama Abla, Liliia Anderzhanova, Nira Arad-Cohen, Itziar Astigarraga, Miriam Ben-Harosh, Francesco Ceppi, Nicole Bodmer, Triantafyllia Brozou, Luciano Dalla-Pozza, Gabriele Escherich, Roula Farah, Amber Gibson, Henrik Hasle, Julieta Hoveyan, Elad Jacoby, Janez Jazbec, Alexandra Kolenova, Jelena Lazic, Luca Lo Nigro, Lane Miller, Vassilios Papadakis, Lucie Pecheux, Marta Pillon, Ifat Sarouk, Jan Stary, Eftichia Stiakaki, Sarah K. Tasian, Thai Hoa Tran, Marek Ussowicz, Jose Jaime Verdu-Amoros, Anna Wakulinska, Joanna Zawitkowska, Dominique Stoppa-Lyonnet, Malcolm Taylor, Yosef Shiloh, Shai Izraeli, Ronit Nirel, Veronique Minard-Colin, Andishe Attarbaschi, Arndt Borkhardt

Blood (2023) 142 (Supplement 1): 520.

https://doi.org/10.1182/blood-2023-179333

Published: 2023

Journal Articles

Epigenetic Profiling and Machine Learning for Enhanced Risk Stratification in Pediatric Acute Lymphoblastic Leukemia

Adrian Mosquera Orgueira, Olga Krali, Andres Peleteiro Raindo, Jose Angel Diaz Arias, Marta Sonia Gonzalez Perez, Manuel Perez Encinas, Manuel Fernandez Sanmartin, Natalia Alonso Vence, Daniel Sinnett, Mats Heyman, Gudmar Lönnerholm, Ulrika Norén-Nyström, Kjeld Schmiegelow, Jessica Nordlund

Blood (2023) 142 (Supplement 1): 4353.

https://doi.org/10.1182/blood-2023-179156

Published: 2023

Journal Articles

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

Signe Modvig, Hanna Thorsson, Bodil Als-Nielsen, Claus Christensen, Nina Friesgaard Øbro, Hans O. Madsen, Henrik Lilljebjörn, Kjeld Schmiegelow, Thoas Fioretos, Hanne Vibeke Marquart

Blood (2023) 142 (Supplement 1): 4345.

https://doi.org/10.1182/blood-2023-188631

Published: 2023

Journal Articles

The Role of Small Nucleolar RNAs As Putative Biomarkers of Chemoresistance in Pediatric Acute Lymphoblastic Leukemia

Olga Krali, Anna Pia Enblad, Kristin Blom, Claes Andersson, Britt-Marie Frost, Josefine Palle, Arja Harila, Olli Lohi, Erik Forestier, Jukka Kanerva, Trond Flægstad, Ólafur G Jónsson, Kjeld Schmiegelow, Mats Heyman, Peter Nygren, Rolf Larsson, Gudmar Lönnerholm, Jessica Nordlund

Blood (2023) 142 (Supplement 1): 6064.

https://doi.org/10.1182/blood-2023-185687

Published: 2023

Journal Articles

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Blood (2023) 141 (7): 743–755.

https://doi.org/10.1182/blood.2022016975

Published: 2023

Includes: Supplemental data

Journal Articles

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Hanna Thorsson, Rasmus Henningsson, Noelia Puente-Moncada, Carl Sandén, Signe Modvig, Marianne Rissler, Kajsa Paulsson, Anders Castor, Cornelis Jan Pronk, Hanne Vibeke Marquart, Kjeld Schmiegelow, Christina Orsmark-Pietras, Henrik Lilljebjörn, Thoas Fioretos

Blood (2022) 140 (Supplement 1): 3467–3468.

https://doi.org/10.1182/blood-2022-163031

Published: 2022

Journal Articles

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

Blood (2022) 140 (Supplement 1): 3403–3404.

https://doi.org/10.1182/blood-2022-156731

Published: 2022

Journal Articles

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N van Leeuwen

Blood (2022) 140 (Supplement 1): 3483–3485.

https://doi.org/10.1182/blood-2022-157431

Published: 2022

Journal Articles

Pharmacokinetics and Immunogenicity of the First Doses of Peg-Asparaginase -an Alltogether Pilot Study

Merete Eybye Dam, Maddalena Centanni, Lena Friberg, Mats Karlsson, Line Stensig Lynggaard, Inga M. Johannsdottir, Hilde Skuterud Wik, Mats Heyman, Johan Malmros, Helene Hallböök, Goda Elizabeta Vaitkeviciene, Laimonas Griskevicius, Ólafur Gísli Jónsson, Ulrik Malthe Overgaard, Kjeld Schmiegelow, Birgitte Klug Albertsen

Blood (2022) 140 (Supplement 1): 8886–8887.

https://doi.org/10.1182/blood-2022-168655

Published: 2022

Journal Articles

Bone Marrow Plasma Proteome Analysis By Differential Ultracentrifugation and Tandem Mass Spectrometry Allow for Characterization of Leukemia-Derived Extracellular Vesicles in Patients with Acute Lymphoblastic Leukemia

Ole Østergaard, Hanne Vibeke Marquart, Maria Thastrup, Christian Mirian, Bodil Als-Nielsen, Kjeld Schmiegelow, Jesper V Olsen, Signe Modvig

Blood (2022) 140 (Supplement 1): 3473–3474.

https://doi.org/10.1182/blood-2022-166141

Published: 2022

Journal Articles

Remission, treatment failure, and relapse in pediatric ALL: an international consensus of the Ponte-di-Legno Consortium

Blood (2022) 139 (12): 1785–1793.

https://doi.org/10.1182/blood.2021012328

Published: 2022

Includes: Supplemental data

NARROW

Cerebrospinal Fluid Flow Cytometry Improves Patient Stratification in Central Nervous System Acute Lymphoblastic Leukaemia but Requires Careful Standardization: Results from the ALLTogether1 CSF-FLOW Sub-Study

Diagnosing and Staging Central Nervous System Involvement in Pediatric ALL: A Global Survey on Its Heterogeneity

Allopurinol Add-on Treatment - Promising Approach to Opitimize Maintenance Therapy for Acute Lymphoblastic Leukemia in Children

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4 -r cases

ATM germ line pathogenic variants affect outcomes in children with ataxia-telangiectasia and hematological malignancies

Mapping Chemo-Resistance Profiles of Pediatric Acute Leukemia through Integration of Ex-Vivo Drug Screens with Molecular Data

Single-Cell Genomics Details the Maturation Block in BCP-ALL and Identifies Therapeutic Vulnerabilities in DUX4 -Rearranged Cases

STAG2/LMO2 Gamma-Delta (γδ) T-ALL: Identification and Characterization of an Extremely High Risk Group of T-ALL in the Very Young

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

ATM Germline Pathogenic Variants Affect Treatment Outcomes in Children with Acute Lymphoblastic Leukemia/Lymphoma and Ataxia Telangiectasia

Epigenetic Profiling and Machine Learning for Enhanced Risk Stratification in Pediatric Acute Lymphoblastic Leukemia

Single-Cell Transcriptomics Points to a Role of Stemness and Bone Marrow Niche Interactions in the Poor Response to Induction Therapy in T-Cell Acute Lymphoblastic Leukemia

The Role of Small Nucleolar RNAs As Putative Biomarkers of Chemoresistance in Pediatric Acute Lymphoblastic Leukemia

EBV-driven lymphoid neoplasms associated with pediatric ALL maintenance therapy

Single Cell Multi-Omic Profiling of Acute Lymphoblastic Leukemia Identifies Altered Cellular Pathways and Highlights Heterogeneity in the Maturation Block of DUX4 -Rearranged ALL

Treatment Outcomes of Childhood Picalm:MLLT10 + Acute Leukemias: An International Retrospective Study

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Pharmacokinetics and Immunogenicity of the First Doses of Peg-Asparaginase -an Alltogether Pilot Study

Bone Marrow Plasma Proteome Analysis By Differential Ultracentrifugation and Tandem Mass Spectrometry Allow for Characterization of Leukemia-Derived Extracellular Vesicles in Patients with Acute Lymphoblastic Leukemia

Remission, treatment failure, and relapse in pediatric ALL: an international consensus of the Ponte-di-Legno Consortium

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American Society of Hematology

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American Society of Hematology

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