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Peter M. Hoogerbrugge
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Journal Articles

ABL-Class Fusion Gene Induced Pediatric CML Presenting As ALL

Peter M. Hoogerbrugge, Maaike Luesink, Judith M. Boer, Inge Van Outersterp, Edwin Sonneveld, Anja De Jong, Stefan Nierkens, Vincent H.J. Van Der Velden, Arjan Buijs, Monique L. den Boer
Journal: Blood
Blood (2024) 144 (Supplement 1): 5851.
https://doi.org/10.1182/blood-2024-203064
Published: 2024
Journal Articles

Implementation of Continuous Pegasparaginase Dosing without an Asparaginase-Free Interval Reduces Hypersensitivity in Children with Newly Diagnosed Acute Lymphoblastic Leukemia: Results of the DCOG ALL11 Pegasparaginase Randomization

Leiah J. Brigitha, Rob Pieters, Marta F. Fiocco, Hester A. de Groot-Kruseman, Marc Bierings, Cor Van Den Bos, Valerie de Haas, Peter M. Hoogerbrugge, Wim J.E. Tissing, Margreet A. Veening, Inge M. Van Der Sluis
Journal: Blood
Blood (2023) 142 (Supplement 1): 2883.
https://doi.org/10.1182/blood-2023-173359
Published: 2023
Journal Articles

Drug Response Profiling Informs Personalized Bridging to Cell Therapy for Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Fabio D. Steffen, Andrej Lissat, Julia Alten, Cornelia Eckert, Nicole Bodmer, Bodil E. Thorhauge Als-Nielsen, Adriana Balduzzi, Barbara Buldini, Sarah Elitzur, Andras Kriston, Gergely Nyiri, Imre Västrik, Ferenc Kovacs, Francesco Ceppi, Lucie Sramkova, Larissa Schori, Arianna Arpagaus, Silvia Gutnik, Andishe Attarbaschi, Birgitte Klug Albertsen, Jeanette Greiner, Marc Ansari, Judith M. Boer, Elad Jacoby, Martin Stanulla, Uri Ilan, Peter M. Hoogerbrugge, Tim Lammens, Barbara De Moerloose, Petter Svenberg, Nicolas von der Weid, David O'Connor, Hélène Cavé, Franco Locatelli, Martin Schrappe, André Baruchel, Andreas Kulozik, Kjeld Schmiegelow, Gunnar Cario, Arend von Stackelberg, Peter Horvath, Beat Bornhauser, Jean-Pierre Bourquin
Journal: Blood
Blood (2023) 142 (Supplement 1): 4350.
https://doi.org/10.1182/blood-2023-179306
Published: 2023
Journal Articles

Variable Immune Response Following BNT162b2 mRNA COVID-19 Vaccination in Pediatric Patients with Hematological Malignancies Under Treatment

Juliëtte Schmidt, Peter M. Hoogerbrugge, Caroline Lindemans, Stefan Nierkens, Robert S. Van Binnendijk, Louis J Bont, Wim J.E. Tissing
Journal: Blood
Blood (2022) 140 (Supplement 1): 6130–6131.
https://doi.org/10.1182/blood-2022-162258
Published: 2022
Journal Articles

Dutch ALL11 Study: Improved Outcome for Acute Lymphoblastic Leukemia By Prolonging Therapy for IKZF1 Deletion and Decreasing Therapy for ETV6::RUNX1, Down Syndrome and Prednisone Poor Responders

Rob Pieters, Hester A. De Groot-Kruseman, Femke Verwer, Merian van Overveld, Edwin Sonneveld, Marta Fiocco, Vincent H.J. van der Velden, Berna Beverloo, Marc Bierings, Valerie De Haas, Peter M. Hoogerbrugge, Inge M. Van Der Sluis, Wim J.E. Tissing, Margreet Veening, Judith M. Boer, Monique L. den Boer
Journal: Blood
Blood (2022) 140 (Supplement 1): 519–520.
https://doi.org/10.1182/blood-2022-165931
Published: 2022
Journal Articles

The Prognostic Effect of IKZF1 Deletions in ETV6 :: RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia

Anna Østergaard, Amir Enshaei, Rob Pieters, Ajay Vora, Martin A. Horstmann, Gabriele Escherich, Bertil Johansson, Mats Heyman, Kjeld Schmiegelow, Peter M. Hoogerbrugge, Monique L. den Boer, Roland P. Kuiper, Anthony V. Moorman, Judith M. Boer, Frank N van Leeuwen
Journal: Blood
Blood (2022) 140 (Supplement 1): 3483–3485.
https://doi.org/10.1182/blood-2022-157431
Published: 2022
Journal Articles

Mutational Mechanisms in Pediatric Acute Lymphoblastic Leukemia with Multiple Relapses

Cédric G van der Ham, Stefan H Lelieveld, Željko Antic, Marley Yeong, Lianne C Suurenbroek, Dorette S van Ingen Schenau, Lennart A. Kester, Liset Westera, Edwin Sonneveld, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Frank N van Leeuwen, Roland P. Kuiper
Journal: Blood
Blood (2022) 140 (Supplement 1): 3463–3464.
https://doi.org/10.1182/blood-2022-159410
Published: 2022
Journal Articles

ALL-REZ BFM 2002 Is Associated with Improved Outcome as Compared to ALL-R3 Strategy in Children with Standard Risk Isolated CNS Relapse of Acute Lymphoblastic Leukemia, while Maintaining Comparable Efficacy in Patients with Bone Marrow Relapse. Results of the Multi-National, Multi-Center Trial IntReALL SR 2010

Arend von Stackelberg, Jean-Pierre Bourquin, Martin Zimmermann, Tamas Revesz, Andishe Attarbaschi, Alina Ferster, Lucie Sramkova, Thomas Leth Frandsen, Päivi Maria Lähteenmäki, Ronit Elhasid, Hidemi Toyoda, Peter M. Hoogerbrugge, Inga M. Johannsdottir, Ximo Duarte, Denise Bonney, Vaskar Saha, Ingo G. Steffen, Andrej Lissat, Christiane Chen-Santel, Cornelia Eckert, Andre Baruchel, Arnaud Petit, Hélène Cavé, Carmelo Rizzari, Giovanni Cazzaniga, Luciana Vinti, Pierre Rohrlich, Franco Locatelli
Journal: Blood
Blood (2022) 140 (Supplement 1): 3247–3249.
https://doi.org/10.1182/blood-2022-166234
Published: 2022
Journal Articles

Genomic Architecture and Clonal Dynamics of Early Relapsed BCP-ALL

Zeljko Antic, MD, Jiangyan Yu, MSc, Simon V. van Reijmersdal, Renske Kuiper, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2016) 128 (22): 4072.
https://doi.org/10.1182/blood.V128.22.4072.4072
Published: 2016
Journal Articles

Integration of genetic and clinical risk factors improves prognostication in relapsed childhood B-cell precursor acute lymphoblastic leukemia

CME Clinical Trials & Observations
Julie A. E. Irving, Amir Enshaei, Catriona A. Parker, Rosemary Sutton, Roland P. Kuiper, Amy Erhorn, Lynne Minto, Nicola C. Venn, Tamara Law, Jiangyan Yu, Claire Schwab, Rosanna Davies, Elizabeth Matheson, Alysia Davies, Edwin Sonneveld, Monique L. den Boer, Sharon B. Love, Christine J. Harrison, Peter M. Hoogerbrugge, Tamas Revesz, Vaskar Saha, Anthony V. Moorman
Journal: Blood
Blood (2016) 128 (7): 911–922.
https://doi.org/10.1182/blood-2016-03-704973
Published: 2016
Includes: Supplemental data
Journal Articles

Genetic Architecture of Relapsed Pediatric B Cell Precursor Acute Lymphoblastic Leukemia Are Related to the Intensity of Upfront Therapy

Jiangyan Yu, MSc, Esmé Waanders, PhD, Simon V. van Reijmersdal, Edwin Sonneveld, PhD, Frank N. van Leeuwen, PhD, Rob Pieters, MD PhD, Ad Geurts van Kessel, PhD, Peter M. Hoogerbrugge, MD PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2015) 126 (23): 247.
https://doi.org/10.1182/blood.V126.23.247.247
Published: 2015
Journal Articles

Accurate Detection of Low Mosaic Mutations Associated with Therapy Resistance in Pediatric Acute Lymphoblastic Leukemia Using Single Molecule Tagging and Deep-Sequencing

Jiangyan Yu, MSc, Simon V. van Reijmersdal, Alexander Hoischen, PhD, Edwin Sonneveld, PhD, Peter M. Hoogerbrugge, MD PhD, Esmé Waanders, PhD, Roland P. Kuiper, PhD
Journal: Blood
Blood (2015) 126 (23): 2608.
https://doi.org/10.1182/blood.V126.23.2608.2608
Published: 2015
Journal Articles

Cathepsin B Mediated Lysosomal Degradation in Macrophages Controls the Pharmacokinetics of the Therapeutic Protein Asparaginase

Laurens T Van Der Meer, PhD, Samantha YA Terry, PhD, Dorette van Ingen Schenau, MSc, Kiki Andree, MSc, Gerben M Franssen, BSc, Debbie Roeleveld, MSc, Bart Metselaar, PhD, Thomas Reinheckel, PhD, Peter M Hoogerbrugge, MD PhD, Otto C Boerman, PhD, Frank N van Leeuwen, PhD
Journal: Blood
Blood (2015) 126 (23): 3768.
https://doi.org/10.1182/blood.V126.23.3768.3768
Published: 2015
Journal Articles

Post Induction Minimal Residual Disease Levels Identifies a Group of High Risk Relapsed Childhood Acute Lymphoblastic Leukemia (rALL) with a Favorable Outcome Independent of Induction Therapy

Catriona Anne Parker, PhD, Marie Reeves, MSc, Sharon Love, MSc, Jeremy Hancock, PhD, Peter M Hoogerbrugge, MD PhD, Rosemary Sutton, Tom Revesz, MD, Vaskar Saha, PhD FRCP, FRCPath
Journal: Blood
Blood (2015) 126 (23): 1294.
https://doi.org/10.1182/blood.V126.23.1294.1294
Published: 2015
Journal Articles

Targeted Locus Amplification & Next Generation Sequencing for the Detection of Recurrent and Novel Gene Fusions for Improved Treatment Decisions in Pediatric Acute Lymphoblastic Leukemia

Roland P. Kuiper, PhD, Simon V. van Reijmersdal, Marieke Simonis, PhD, Jiangyan Yu, MSc, Edwin Sonneveld, PhD, Blanca Scheijen, PhD, Judith M. Boer, PhD, Aurélie Boeree, BSc, Petra Klous, MSc, Peter M Hoogerbrugge, MD PhD, Mehmet Yilmaz, MSc, Frank N. van Leeuwen, PhD, Monique L. Den Boer, PhD, Erik Splinter, PhD
Journal: Blood
Blood (2015) 126 (23): 696.
https://doi.org/10.1182/blood.V126.23.696.696
Published: 2015
Journal Articles

Tumor Suppressors BTG1 and IKZF1 Cooperate during Mouse Leukemia Development and Impact Relapse Rate in Childhood Acute Lymphoblastic Leukemia

Blanca Scheijen, PhD, Esther Tijchon, Dorette van Ingen Schenau, Rene Marke, Liesbeth van Emst, Laurens T Van Der Meer, PhD, Roland P Kuiper, PhD, Judith M. Boer, PhD, Rob Pieters, MD PhD, Peter M Hoogerbrugge, MD PhD, Monique L. Den Boer, PhD, Frank N van Leeuwen, PhD
Journal: Blood
Blood (2015) 126 (23): 905.
https://doi.org/10.1182/blood.V126.23.905.905
Published: 2015
Journal Articles

Prognostic Value of Rare IKZF1 deletions in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia: An International Collaborative Study

Judith M. Boer, PhD, Arian van der Veer, MD PhD, Dimitris Rizopoulos, PhD, Marta Fiocco, PhD, Edwin Sonneveld, PhD, Hester A. de Groot-Kruseman, PhD, Roland P. Kuiper, PhD, Peter M. Hoogerbrugge, MD PhD, Martin A. Horstmann, MD PhD, Marketa Zaliova, MD PhD, Chiara Palmi, Jan Trka, MD, PhD, Prof., Eva Fronkova, MD, PhD, Mariana Emerenciano, PhD, Maria do Socorro Pombo-de-Oliveira, PhD, Wojciech Mlynarski, MDPhD, Tomasz Szczepanski, MD PhD, Karin Nebral, PhD, Andishe Attarbaschi, MD PhD, Nicola C. Venn, PhD, Rosemary Sutton, PhD, Claire Schwab, BSc, Amir Enshaei, PhD, Ajay J. Vora, Martin Stanulla, MD, Martin Schrappe, MD, Gianni Cazzaniga, PhD, Valentino Conter, MD PhD, Martin Zimmerman, PhD, Anthony V. Moorman, PhD, Rob Pieters, Monique L. Den Boer, MSc, PhD
Journal: Blood
Blood (2014) 124 (21): 368.
https://doi.org/10.1182/blood.V124.21.368.368
Published: 2014
Journal Articles

Aggravated Bone Density Decline after Symptomatic Osteonecrosis in Children with Acute Lymphoblastic Leukemia

Marissa den Hoed, S.M.F. Pluijm, Mariël L. Te Winkel, Hester A. de Groot-Kruseman, PhD, Marta Fiocco, PhD, Peter M. Hoogerbrugge, MD PhD, J.a. Leeuw, Marrie Bruin, MD PhD, Inge M. van der Sluis, MD PhD, Dorine Bresters, MD PhD, Maarten H. Lequin, MD PhD, Jan C. Roos, A. Veerman, MD PhD, Rob Pieters, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2014) 124 (21): 2260.
https://doi.org/10.1182/blood.V124.21.2260.2260
Published: 2014
Journal Articles

The Negative Impact of Underweight and Weight Loss on Survival of Children with Acute Lymphoblastic Leukemia

Marissa den Hoed, S.M.F. Pluijm, Hester A. de Groot-Kruseman, PhD, Mariël L. Te Winkel, Erica L.T. van den Akker, MD PhD, Peter M. Hoogerbrugge, MD PhD, Henk van den Berg, MD, J.a. Leeuw, Marrie Bruin, MD PhD, Dorine Bresters, MD PhD, A.J.P. Veerman, MD PhD, Marta Fiocco, PhD, Rob Pieters, MD PhD, Marry M. van den Heuvel-Eibrink
Journal: Blood
Blood (2014) 124 (21): 2261.
https://doi.org/10.1182/blood.V124.21.2261.2261
Published: 2014
Journal Articles

Tumor Suppressors Btg1 and Btg2 Regulate B Lineage Commitment through Modulation of Ebf1 Activity

Esther Tijchon, MSc, Liesbeth van Emst, Bsc, Dorette van Ingen Schenau, MSc, Laurensia Yuniati, MSc, Jorn Havinga, MSc, Felice Tirone, PhD, Jean-Pierre Rouault, PhD, Peter M Hoogerbrugge, MD PhD, Frank N. van Leeuwen, PhD, Blanca Scheijen, PhD
Journal: Blood
Blood (2014) 124 (21): 4311.
https://doi.org/10.1182/blood.V124.21.4311.4311
Published: 2014