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Chiara F. Magnani
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Journal Articles

CD19 CAR T Cells Drive a Remodeling of the Immune Microenvironment Associated with T-Cell Dysfunction in Acute Lymphoblastic Leukemia

Marianna Ponzo, Lorenzo Drufuca, Chiara Buracchi, Marco M Sindoni, Silvia Nucera, Cristina Bugarin, Ramona Bason, Grazisa Rossetti, Raul Bonnal, Cristian Meli, Benedetta Rambaldi, Federico Lussana, Silvia Ferrari, Alex Moretti, Giulia Risca, Christian Pellegrino, Markus G. Manz, Stefania Galimberti, Alessandro Rambaldi, Andrea Biondi, Giuseppe Gaipa, Massimiliano Pagani, Chiara F. Magnani
Journal: Blood
Blood (2024) 144 (Supplement 1): 2834.
https://doi.org/10.1182/blood-2024-206806
Published: 2024
Journal Articles

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Bühler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3435.
https://doi.org/10.1182/blood-2023-185853
Published: 2023
Journal Articles

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Chiara F Magnani, Renier Myburgh, Norman F Russkamp, Steve Pascolo, Judith A Shizuru, Dario Neri, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2808.
https://doi.org/10.1182/blood-2021-145195
Published: 2021
Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty in Pediatric and Adult Patients with Acute Lymphoblastic Leukemia Relapsed Post-HSCT

Chiara F Magnani, Giuseppe Gaipa, Federico Lussana, Giuseppe Gritti, Daniela Belotti, Sara Napolitano, Chiara Buracchi, Gian Maria Borleri, Benedetta Rambaldi, Silvia Zaninelli, Giuliana Rizzuto, Gianluca Cavallaro, Sarah Tettamanti, Giovanni Cazzaniga, Stefania Galimberti, Silvia Ferrari, Martino Introna, Adriana Balduzzi, Maria Grazia Valsecchi, Giuseppe Dastoli, Alessandro Rambaldi, Andrea Biondi
Journal: Blood
Blood (2021) 138 (Supplement 1): 472.
https://doi.org/10.1182/blood-2021-148703
Published: 2021
Journal Articles

Donor-Derived CAR T Cells Engineered with Sleeping Beauty Achieve Anti-Leukemic Activity without Severe Toxicity

Chiara F Magnani, Giuseppe Gaipa, PhD, Federico Lussana, MD, Daniela Belotti, Giuseppe Gritti, MD PhD, Sara Napolitano, MD, Chiara Buracchi, PhD, Gian Maria Borleri, Silvia Zaninelli, Giuliana Rizzuto, Sarah Tettamanti, PhD, Valentina Colombo, Giovanni Cazzaniga, PhD, Benedetta Cabiati, Attilio Rovelli, MD, Ettore Biagi, MD PhD, Stefania Galimberti, PhD, Fabrizio Benedicenti, Eugenio Montini, PhD, Silvia Ferrari, MD, Martino Introna, MD, Adriana Balduzzi, MD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Alessandro Rambaldi, MD, Andrea Biondi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34.
https://doi.org/10.1182/blood-2020-141236
Published: 2020
Journal Articles

Preclinical Assessment of Non-Virally Engineered CD33.CAR Cytokine-Induced Killer (CIK) Cells in Chemoresistant AML Patient-Derived Xenografts

Maria Caterina Rotiroti, PhD, Chiara Buracchi, PhD, Silvia Arcangeli, PhD, Chiara F Magnani, PhD, Claudia Cappuzzello, PhD, Zsuzsanna Izsvak, PhD, Stefania Galimberti, PhD, Maria Grazia Valsecchi, PhD, Giuseppe Dastoli, MD, Marta Serafini, PhD, Ettore Biagi, MD, Andrea Biondi, MD, Sarah Tettamanti, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2665.
https://doi.org/10.1182/blood-2019-130399
Published: 2019
Journal Articles

Donor-Derived CD19 CAR Cytokine Induced Killer (CIK) Cells Engineered with Sleeping Beauty Transposon for Relapsed B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Chiara F Magnani, PhD, Giuseppe Gaipa, PhD, Daniela Belotti, Giada Matera, Sarah Tettamanti, PhD, Benedetta Cabiati, Chiara Buracchi, PhD, Grazia Fazio, Silvia Zaninelli, Silvia Rigamonti, Stefania Cesana, Valentina Colombo, Giovanni Cazzaniga, PhD, Attilio Rovelli, MD, Adriana Balduzzi, MD, Sara Napolitano, MD, Fabrizio Benedicenti, Eugenio Montini, PhD, Gian Maria Borleri, Silvia Ferrari, MD, Giuseppe Gritti, MD PhD, Federico Lussana, MD, Martino Introna, MD, Alessandro Rambaldi, MD, Giuseppe Dastoli, MD, Andrea Biondi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 200.
https://doi.org/10.1182/blood-2019-125894
Published: 2019
Journal Articles

Sleeping Beauty Modified CAR+ Lymphocytes Engraft and Exhibit Anti-Tumor Activity in Patient-Derived Xenograft Models of Acute Lymphoblastic Leukemia

Chiara F. Magnani, PhD, Claudia Mezzanotte, Claudia Cappuzzello, PhD, Fabrizio Benedicenti, Michela Bardini, PhD, Sarah Tettamanti, PhD, Grazia Fazio, PhD, Gianni Cazzaniga, PhD, Laurence J.N. Cooper, MD PhD, Eugenio Montini, PhD, Andrea Biondi, MD, Ettore Biagi, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4022.
https://doi.org/10.1182/blood.V128.22.4022.4022
Published: 2016
Journal Articles

Balance of Anti-CD123 Chimeric Antigen Receptor (CAR) Binding Affinity and Density for the Treatment of Acute Myeloid Leukemia

Silvia Arcangeli, PhD, Marco Bardelli, PhD, Maria Caterina Rotiroti, Luca Simonelli, PhD, Chiara F. Magnani, PhD, Luca Varani, PhD, Andrea Biondi, MD, Ettore Biagi, MD, Sarah Tettamanti, PhD
Journal: Blood
Blood (2016) 128 (22): 2163.
https://doi.org/10.1182/blood.V128.22.2163.2163
Published: 2016
Journal Articles

Unraveling the Efficacy and Safety Profiles of Anti-CD123 Chimeric Antigen Receptors (CARs) in a Model of Acute Myeloid Leukemia Immunotherapy By Investigating CAR Binding Affinity and Density Variables

Silvia Arcangeli, Marco Bardelli, Sarah Tettamanti, Maria Caterina Rotiroti, Luca Simonelli, Chiara F Magnani, Luca Varani, Andrea Biondi, Prof, MD, Ettore Biagi, MD
Journal: Blood
Blood (2015) 126 (23): 1359.
https://doi.org/10.1182/blood.V126.23.1359.1359
Published: 2015
Journal Articles

Receptor Repertoire Reconstitution Suggests Acquisition of Patient-Specific Tolerance by Natural Killer Cells Arising from Hematopoietic Progenitor Stem Cells after Haploidentical Transplantation.

Luca Vago, MD, Simona Di Terlizzi, BS, Elisabetta Zino, BS, Chiara F. Magnani, BS, Maria T. Lupo Stanghellini, MD, Zulma Magnani, PhD, Benedetta Mazzi, BS, Daniela Clerici, MD, Attilio Bondanza, MD, Marco Bregni, MD, Silvano Rossini, MD, Jacopo Peccatori, MD, Chiara Bonini, MD, Fabio Ciceri, MD, Claudio Bordignon, MD, Katharina Fleischhauer, MD
Journal: Blood
Blood (2005) 106 (11): 2905.
https://doi.org/10.1182/blood.V106.11.2905.2905
Published: 2005