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Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2023) 142 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2023-185567
Published: 2023
Journal Articles

Efficient Combinatorial Adaptor-Mediated Targeting of Acute Myeloid Leukemia with CAR T-Cells

Laura Volta, Renier Myburgh, Christian Pellegrino, Christian Koch, Monique Maurer, Francesco Manfredi, Mara Hofstetter, Anne Kaiser, Florin Schneiter, Jan Müller, Marco M. Bühler, Roberto De Luca, Nicholas Favalli, Chiara F. Magnani, Timm Schroeder, Dario Neri, Markus G. Manz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3435.
https://doi.org/10.1182/blood-2023-185853
Published: 2023
Journal Articles

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Chiara F Magnani, Renier Myburgh, Norman F Russkamp, Steve Pascolo, Judith A Shizuru, Dario Neri, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2808.
https://doi.org/10.1182/blood-2021-145195
Published: 2021
Journal Articles

Efficient Human Acute Myeloid Leukemia Targeting By Universal Chimeric Antigen Receptor T-Cells Via Combinatorial Use of Linkers

Laura Volta, Renier Myburgh, Christian Edoardo Pellegrino, Jan Müller, C. Matthias Wilk, Dario Neri, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2781.
https://doi.org/10.1182/blood-2021-151039
Published: 2021
Journal Articles

CD117 As an Immunotherapeutic Target in Advanced Forms of Mastocytosis

Anne Kaiser, Renier Myburgh, Laura Volta, Christian Edoardo Pellegrino, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2538.
https://doi.org/10.1182/blood-2021-145876
Published: 2021
Journal Articles

A Bispecific Antibody Targeting CD117 and CD3 Enables T Cell Mediated Killing of CD117-Expressing Healthy and Malignant Hematopoietic Cells

Jonathan D Kiefer, Renier Myburgh, Norman F Russkamp, Laura Volta, Adrian Guggisberg, Omar Abdelmotaleb, Jacqueline Mock, Dario Neri, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2354.
https://doi.org/10.1182/blood-2021-147676
Published: 2021
Journal Articles

Anti-Human CD117 CAR T-Cells Efficiently Eliminate Hematopoietic Stem and CD117-Positive AML Cells

Renier Myburgh, PhD BSc, MSc, Jonathan Kiefer, Msc, Norman F Russkamp, Dr. MD, Alexander Simonis, Dr. MD, Surema Pfister, C. Matthias Wilk, MD, Chiara Magnani, PhD, Antonia MS Mueller, MD, Burkhard Becher, Prof. Dr., Maries van den Broek, Prof. Dr., Dario Neri, Prof. Dr., Markus G. Manz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4063.
https://doi.org/10.1182/blood-2018-99-118230
Published: 2018
Journal Articles

Homozygous calreticulin mutations in patients with myelofibrosis lead to acquired myeloperoxidase deficiency

Alexandre P. A. Theocharides, Pontus Lundberg, Asvin K. K. Lakkaraju, Veronika Lysenko, Renier Myburgh, Adriano Aguzzi, Radek C. Skoda, Markus G. Manz
Journal: Blood
Blood (2016) 127 (25): 3253–3259.
https://doi.org/10.1182/blood-2016-02-696310
Published: 2016
Includes: Supplemental data