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Jonas Fullin
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Journal Articles

The Pathogenesis of Therapy-Related Myeloid Neoplasms from TP53 -Mutant Clonal Hematopoiesis

Jonas Fullin, Ebru Topçu, Roman R. Schimmer, Nancy Klemm, Karolina Zielinska, Christian Koch, Francisco Caiado, Cyril Doerdelmann, Melissa Lock, Joelle Tchinda, Markus G. Manz, Massimo Lopes, Steffen Boettcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 41.
https://doi.org/10.1182/blood-2024-205209
Published: 2024
Journal Articles

Somatic TP53 Mutations Rescue the Hematopoietic Stem and Progenitor Cell Defect at the Expense of Increased Risk for Myeloid Malignancies in ERCC6L2 -Associated Inherited Bone Marrow Failure Syndrome

Roman R. Schimmer, Nancy Klemm, Ebru Topçu, Jonas Fullin, Karolina Zielinska, Cyril Doerdelmann, Melissa Lock, Milena Treacy, Francisco Caiado, Nadja Dietliker, Rahel Schwotzer, Markus G. Manz, Massimo Lopes, Steffen Boettcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 193.
https://doi.org/10.1182/blood-2024-204925
Published: 2024
Journal Articles

Modelling the Evolution of Clonal Hematopoiesis to Myeloid Malignancies Under the Selective Pressure of Anti-Cancer Therapy

Christian Koch, Jonas Fullin, Ebru Topçu, Nancy Klemm, Karolina Zielinska, Monika Hebeisen, Joelle Tchinda, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 5651.
https://doi.org/10.1182/blood-2024-205797
Published: 2024
Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2023) 142 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2023-185567
Published: 2023
Journal Articles

Aging drives Tet2 +/− clonal hematopoiesis via IL-1 signaling

Francisco Caiado, Larisa V. Kovtonyuk, Nagihan G. Gonullu, Jonas Fullin, Steffen Boettcher, Markus G. Manz
Journal: Blood
Blood (2023) 141 (8): 886–903.
https://doi.org/10.1182/blood.2022016835
Published: 2023
Includes: Supplemental data