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Alexandre Theocharides
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Journal Articles

TP53 Deficiency in AML Confers Resistance to CAR T-Cells That Can be Overcome By Targeting the Cholesterol or Wnt Pathways

Jan Mueller, Roman Schimmer, Christian Koch, Florin Schneiter, Jonas Fullin, Veronika Lysenko, Renier Myburgh, Laura Volta, Alexandre Theocharides, Kari Kurppa, Benjamin L. Ebert, Timm Schroeder, Markus G. Manz, Steffen Boettcher
Journal: Blood
Blood (2023) 142 (Supplement 1): 1019.
https://doi.org/10.1182/blood-2023-185567
Published: 2023
Journal Articles

An International Multicentric Observational Study on the Use of Ruxolitinib in Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea: Results from Interim Analysis

Peter AW te Boekhorst, MD PhD, Alexandre Theocharides, MD, Heinz Gisslinger, MD, Timothy Devos, MD, Eric Lippert, MD PhD, Damianos Sotiropoulos, MD, Miklos Egyed, MD PhD, Valerio De Stefano, MD, Vincenzo Accurso, MD, Alessandra Iurlo, MD PhD, Anders E.A. Dahm, MD PhD, Regina Garcia-Delgado, MD, Nathan Cantoni, MD, Mike Zuurman, PhD, Michael Zaiac, MD, Erik Houtsma, MSc, Amir Iqbal, PhD, Paola Di Matteo, MD PhD, Alberto Alvarez-Larrán, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–10.
https://doi.org/10.1182/blood-2020-134210
Published: 2020
Journal Articles

Characterization of Hematopoietic Differentiation Profiles of MPN Patient-Derived Inducible Pluripotent Stem Cells Harboring Homozygous Vs Heterozygous Calreticulin Mutations

Lijuan Han, MD, Marcelo A. Szymanski Toledo, PhD, Alexandre Theocharides, MD, Angela Maurer, M.Sc, Tim H. Brümmendorf, MD, Martin Zenke, PhD, Nicolas Chatain, PhD, Steffen Koschmieder, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3065.
https://doi.org/10.1182/blood-2018-99-113372
Published: 2018
Journal Articles

Engraftment Of Human Polycythemia Vera CD34+ Cells In hSIRPα-Transgenic-Human-TPO-Expressing RAG2 -/- , IL2Rγ -/- Immunodeficient Mice

Rouven Müller, MD, Alexandre Theocharides, MD, Renate Looser, Radek C. Skoda, M.D., Richard A. Flavell, PhD, Markus G. Manz, MD
Journal: Blood
Blood (2013) 122 (21): 2844.
https://doi.org/10.1182/blood.V122.21.2844.2844
Published: 2013
Journal Articles

Clonal heterogeneity in polycythemia vera patients with JAK2 exon12 and JAK2 -V617F mutations

Brief Report
Sai Li, Robert Kralovics, Gennaro De Libero, Alexandre Theocharides, Heinz Gisslinger, Radek C. Skoda
Journal: Blood
Blood (2008) 111 (7): 3863–3866.
https://doi.org/10.1182/blood-2007-09-111971
Published: 2008
Includes: Supplemental data
Journal Articles

Somatic mutations of JAK2 exon 12 in patients with JAK2 (V617F)-negative myeloproliferative disorders

Brief Report
Daniela Pietra, Sai Li, Angela Brisci, Francesco Passamonti, Elisa Rumi, Alexandre Theocharides, Maurizio Ferrari, Heinz Gisslinger, Robert Kralovics, Laura Cremonesi, Radek Skoda, Mario Cazzola
Journal: Blood
Blood (2008) 111 (3): 1686–1689.
https://doi.org/10.1182/blood-2007-07-101576
Published: 2008
Includes: Supplemental data
Journal Articles

The JAK2-V617F Mutation Load Remains Stable over Several Years in Most Patients with Myeloproliferative Disorders Analyzed in a Retrospective Single Center Study.

Alexandre Theocharides, MD, Renate Looser, Hao-Shen Hui, Andreas S. Buser, MD, Alois Gratwohl, MD, Andre Tichelli, MD, Radek C. Skoda, MD
Journal: Blood
Blood (2007) 110 (11): 2526.
https://doi.org/10.1182/blood.V110.11.2526.2526
Published: 2007
Journal Articles

Several Somatic Mutations of JAK2 Exon 12 Are Found in Patients with a JAK2 (V617F)-Negative Myeloproliferative Disorder That Is Mainly Characterized by Erythrocytosis.

Daniela Pietra, Sai Li, Angela Brisci, Francesco Passamonti, Elisa Rumi, Alexandre Theocharides, Heinz Gissingler, Robert Kralovics, Laura Cremonesi, Radek C. Skoda, Mario Cazzola
Journal: Blood
Blood (2007) 110 (11): 263.
https://doi.org/10.1182/blood.V110.11.263.263
Published: 2007
Journal Articles

Leukemic blasts in transformed JAK2-V617F –positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation.

Brief Report
Alexandre Theocharides, Marjorie Boissinot, François Girodon, Richard Garand, Soon-Siong Teo, Eric Lippert, Pascaline Talmant, Andre Tichelli, Sylvie Hermouet, Radek C. Skoda
Journal: Blood
Blood (2007) 110 (1): 375–379.
https://doi.org/10.1182/blood-2006-12-062125
Published: 2007
Includes: Supplemental data
Journal Articles

Myeloid Blasts in Transformed JAK2-V617F Positive Myeloproliferative Disorders Are Frequently Negative for the JAK2-V617F Mutation.

Alexandre Theocharides, Marjorie Boissinot, Richard Garand, François Girodon, Soon-Siong Teo, Eric Lippert, Andre Tichelli, Sylvie Hermouet, Radek C. Skoda
Journal: Blood
Blood (2006) 108 (11): 375.
https://doi.org/10.1182/blood.V108.11.375.375
Published: 2006
Journal Articles

Acquisition of the V617F mutation of JAK2 is a late genetic event in a subset of patients with myeloproliferative disorders

Brief Report
Robert Kralovics, Soon-Siong Teo, Sai Li, Alexandre Theocharides, Andreas S. Buser, Andre Tichelli, Radek C. Skoda
Journal: Blood
Blood (2006) 108 (4): 1377–1380.
https://doi.org/10.1182/blood-2005-11-009605
Published: 2006
Includes: Supplemental data