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C. Matthias Wilk
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Journal Articles

Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

Michael Spencer Chapman, Emily Mitchell, Kenichi Yoshida, Nicholas Williams, Margarete A. Fabre, Anna Maria Ranzoni, Philip S. Robinson, Lori Kregar, C. Matthias Wilk, Steffen Boettcher, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Stanley Ng, George S Vassiliou, Kate Gowers, Sam Janes, Matt Hoare, Anthony R Green, Ana Cvejic, Markus G. Manz, Elisa Laurenti, Inigo Martincorena, Michael Stratton, Jyoti Nangalia, Tim H.H. Coorens, Peter Campbell
Journal: Blood
Blood (2024) 144 (Supplement 1): 2673.
https://doi.org/10.1182/blood-2024-208773
Published: 2024
Journal Articles

Clonal Dynamics after Haematopoietic Stem Cell Transplantation Using Genome-Wide Somatic Mutations

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Emily Mitchell, Kevin J Dawson, Larisa V. Kovtonyuk, Jan Müller, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell
Journal: Blood
Blood (2022) 140 (Supplement 1): 1572–1573.
https://doi.org/10.1182/blood-2022-166701
Published: 2022
Journal Articles

Bone Marrow-Derived BRAFV600E-Mutated Cells Drive Neurodegeneration in a Mouse Model of Langerhans Cell Histiocytosis

C. Matthias Wilk, Jessica LeBerichel, Flurin Cathomas, George Heaton, Orsolya Török, Aymeric Silvin, Zhenyu Yue, Scott Russo, Florent Ginhoux, Jennifer Picarsic, Carl E. Allen, Miriam Merad
Journal: Blood
Blood (2022) 140 (Supplement 1): 3873.
https://doi.org/10.1182/blood-2022-169842
Published: 2022
Journal Articles

Myeloid Progenitors Define Extent of Disease in Mouse Models of Histiocytic Disorders: BRAF V600E Expression in Monocyte Lineage Recapitulates Erdheim-Chester Phenotype

C. Matthias Wilk, Brooks Scull, Ryan Fleischmann, Tsz-Kwong Man, Kenneth L. McClain, Miriam Merad, Florent Ginhoux, Carl E. Allen
Journal: Blood
Blood (2022) 140 (Supplement 1): 9597.
https://doi.org/10.1182/blood-2022-168116
Published: 2022
Journal Articles

Efficient Human Acute Myeloid Leukemia Targeting By Universal Chimeric Antigen Receptor T-Cells Via Combinatorial Use of Linkers

Laura Volta, Renier Myburgh, Christian Edoardo Pellegrino, Jan Müller, C. Matthias Wilk, Dario Neri, Markus G Manz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2781.
https://doi.org/10.1182/blood-2021-151039
Published: 2021
Journal Articles

Clinical Presentation of Patients with Adult Late-Onset Telomere Biology Disorders - Results from the Aachen Telomeropathy Registry

Fabian Beier, Mareike Tometten, Martin Kirschner, Insa Halfmeyer, Margherita Vieri, Kim Kricheldorf, Angela Maurer, Alexander Roeth, Uwe Platzbecker, Markus P. Radsak, Philippe Schafhausen, Selim Corbacioglu, Britta Hoechsmann, C. Matthias Wilk, Claas Hinze, Jörg Chromik, Alexander Egle, Michael Heuser, Michael Kreuter, Ingo Kurth, Steffen Koschmieder, Jens Panse, Robert Meyer, Susanne Isfort, Tim H Brummendorf
Journal: Blood
Blood (2021) 138 (Supplement 1): 1130.
https://doi.org/10.1182/blood-2021-153630
Published: 2021
Journal Articles

Long-Term Clonal Dynamics upon Allogeneic Haematopoietic Stem Cell Transplantation Revealed Using Somatic Mutations As Clonal Tracking Marks in HSC Donor and Recipient Pairs

Michael Spencer Chapman, C. Matthias Wilk, Steffen Boettcher, Larisa V. Kovtonyuk, Emily Mitchell, Nicholas Williams, Jyoti Nangalia, Markus G Manz, Peter J. Campbell
Journal: Blood
Blood (2021) 138 (Supplement 1): 3813.
https://doi.org/10.1182/blood-2021-146151
Published: 2021
Journal Articles

Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell transplantation

Steffen Boettcher, C. Matthias Wilk, Jochen Singer, Fabian Beier, Elodie Burcklen, Christian Beisel, Monica S. Ventura Ferreira, Elise Gourri, Christoph Gassner, Beat M. Frey, Urs Schanz, Radek C. Skoda, Benjamin L. Ebert, Tim H. Brummendorf, Niko Beerenwinkel, Markus G. Manz
Journal: Blood
Blood (2020) 135 (18): 1548–1559.
https://doi.org/10.1182/blood.2019003079
Published: 2020
Includes: Supplemental data
Journal Articles

Anti-Human CD117 CAR T-Cells Efficiently Eliminate Hematopoietic Stem and CD117-Positive AML Cells

Renier Myburgh, PhD BSc, MSc, Jonathan Kiefer, Msc, Norman F Russkamp, Dr. MD, Alexander Simonis, Dr. MD, Surema Pfister, C. Matthias Wilk, MD, Chiara Magnani, PhD, Antonia MS Mueller, MD, Burkhard Becher, Prof. Dr., Maries van den Broek, Prof. Dr., Dario Neri, Prof. Dr., Markus G. Manz, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4063.
https://doi.org/10.1182/blood-2018-99-118230
Published: 2018
Journal Articles

Similar Quality of Life with 5mg Versus 25mg Lenalidomide Maintenance after First-Line High-Dose Therapy and Autologous Blood Stem Cell Transplantation for Multiple Myeloma: Results of the Lenamain Trial

Amelie Boquoi, MD, Aristoteles Giagounidis, Hartmut Goldschmidt, MD, Michael Heinsch, MD, Mathias J Rummel, MD PhD, Nicolaus Kroeger, David Lopez y Niedenhoff, MD, C. Matthias Wilk, MD, Ingrida Savickaite, MD, Elias K Mai, MD, Carlo Aul, MD, Judith Strapatsas, MD, Ariane Dienst, MD, Mustafa Kondakci, MD, Rainer Haas, MD, Guido Kobbe, Roland Fenk, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2003.
https://doi.org/10.1182/blood-2018-99-110977
Published: 2018
Journal Articles

Detection of Clonal Hematopoiesis Is a Rare Event in Patients with Dyskeratosis Congenita

Martin Kirschner, MD, Angela Maurer, Marcin W. Wlodarski, MD PhD, Monica Sofia Ventura Ferreira, Anne-Sophie Bouillon, MD, Wolfgang Blau, Michael Kreuter, MD, Martin Rosewich, Selim Corbacioglu, MD PhD, Joachim Beck, MD, C. Matthias Wilk, MD, Steffen Koschmieder, Fabian Beier, MD, Tim H. Brummendorf, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2457.
https://doi.org/10.1182/blood.V130.Suppl_1.2457.2457
Published: 2017
Journal Articles

Analysis of the Hematopoietic System in Long-Term Survivors of Allogeneic Stem Cell Transplantation and Their Respective Donors

C. Matthias Wilk, MD, Steffen Boettcher, MD, Fabian Beier, MD, Tim H. Brümmendorf, MD, Markus G Manz, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1996.
https://doi.org/10.1182/blood.V130.Suppl_1.1996.1996
Published: 2017
Journal Articles

Prevalence and Eradication of Colonizing Staphylococcus Aureus in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation

C. Matthias Wilk, MD, Isabel Weber, Carole Rachmühl, Kati Seidl, PhD, Anne Holzmann Bürgel, Antonia MS Müller, MD, Urs Schanz, MD, Annelies S. Zinkernagel, MD PhD MSc
Journal: Blood
Blood (2016) 128 (22): 3413.
https://doi.org/10.1182/blood.V128.22.3413.3413
Published: 2016
Journal Articles

Functional Inhibition of Mesenchymal Stem and Progenitor Cells (MSPC) Significantly Contributes to Hematopoietic Insufficiency with Acute Myeloid Leukemia (AML)

Stefanie Geyh, Manuel Rodríguez-Paredes, Cyrus Khandanpour, MD, Ron-Patrick Cadeddu, Paul Jäger, Christoph Zilkens, Ulrich Dührsen, MD, C. Matthias Wilk, Roland Fenk, MD, Norbert Gattermann, MD PhD, Ulrich Germing, Guido Kobbe, MD, Frank Lyko, PhD, Rainer Haas, MD, Thomas Schroeder, MD
Journal: Blood
Blood (2014) 124 (21): 3492.
https://doi.org/10.1182/blood.V124.21.3492.3492
Published: 2014
Journal Articles

TIMP–1 Plays a Functional Role in CD34. + Hematopoietic Stem and Progenitor Cells.

C. Matthias Wilk, Akos G. Czibere, MD, PhD, Ron-Patrick Cadeddu, Sebastian Buest, Frank A. Schildberg, Marcel A. Lauterbach, Volker Westphal, PhD, Stefan W. Hell, Prof., Rainer Haas, Prof., Ingmar Bruns, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1487.
https://doi.org/10.1182/blood.V114.22.1487.1487
Published: 2009