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Margarete A. Fabre
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Journal Articles

Mutagenic DNA Lesions in Normal Hematopoietic Stem Cells Persist for Years Causing Distinct Patterns of Mutation

Michael Spencer Chapman, Emily Mitchell, Kenichi Yoshida, Nicholas Williams, Margarete A. Fabre, Anna Maria Ranzoni, Philip S. Robinson, Lori Kregar, C. Matthias Wilk, Steffen Boettcher, Krishnaa Mahbubani, Kourosh Saeb-Parsy, Stanley Ng, George S Vassiliou, Kate Gowers, Sam Janes, Matt Hoare, Anthony R Green, Ana Cvejic, Markus G. Manz, Elisa Laurenti, Inigo Martincorena, Michael Stratton, Jyoti Nangalia, Tim H.H. Coorens, Peter Campbell
Journal: Blood
Blood (2024) 144 (Supplement 1): 2673.
https://doi.org/10.1182/blood-2024-208773
Published: 2024
Journal Articles

Causes and Consequences of Clonal Hematopoiesis with Unknown Drivers in 409,553 Whole-Genome Sequenced UK Biobank Participants

Sean Wen, Marcin Karpinski, Dimitrios Vitsios, Sebastian Wasilewski, Slavé Petrovski, Andrew R. Harper, Margarete A. Fabre, George S Vassiliou, Jonathan Mitchell
Journal: Blood
Blood (2024) 144 (Supplement 1): 945.
https://doi.org/10.1182/blood-2024-205118
Published: 2024
Journal Articles

The lifelong natural history of clonal hematopoiesis and its links to myeloid neoplasia

Margarete A. Fabre, George S. Vassiliou
Journal: Blood
Blood (2024) 143 (7): 573–581.
https://doi.org/10.1182/blood.2023019964
Published: 2024
Journal Articles

Prevalence and significance of DDX41 gene variants in the general population

Clinical Trials & Observations
Sruthi Cheloor Kovilakam, Muxin Gu, William G. Dunn, Ludovica Marando, Clea Barcena, Serena Nik-Zainal, Irina Mohorianu, Siddhartha P. Kar, Margarete A. Fabre, Pedro M. Quiros, George S. Vassiliou
Journal: Blood
Blood (2023) 142 (14): 1185–1192.
https://doi.org/10.1182/blood.2023020209
Published: 2023
Includes: Supplemental data
Journal Articles

A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions

Tae-Hoon Shin, Yifan Zhou, Shirley Chen, Stefan Cordes, Max Z. Grice, Xing Fan, Byung-Chul Lee, Aisha A. Aljanahi, So Gun Hong, Kelli L. Vaughan, Julie A. Mattison, Steven G. Kohama, Margarete A. Fabre, Naoya Uchida, Selami Demirci, Marcus A. F. Corat, Jean-Yves Métais, Katherine R. Calvo, Manuel Buscarlet, Hannah Natanson, Kathy L. McGraw, Alan F. List, Lambert Busque, John F. Tisdale, George S. Vassiliou, Kyung-Rok Yu, Cynthia E. Dunbar
Journal: Blood
Blood (2022) 140 (16): 1774–1789.
https://doi.org/10.1182/blood.2021014875
Published: 2022
Includes: Supplemental data
Journal Articles

Clonal hematopoiesis is not significantly associated with COVID-19 disease severity

Clinical Trials & Observations
Yifan Zhou, Ruba Shalhoub, Stephanie N. Rogers, Shiqin Yu, Muxin Gu, Margarete A. Fabre, Pedro M. Quiros, Tae-Hoon Shin, Arch Diangson, Wenhan Deng, Shubha Anand, Wenhua Lu, Matthew Cullen, Anna L. Godfrey, Jacobus Preller, Jerome Hadjadj, Emmanuelle Jouanguy, Aurélie Cobat, Laurent Abel, Frederic Rieux-Laucat, Benjamin Terrier, Alain Fischer, Lara Novik, Ingelise J. Gordon, Larisa Strom, Martin R. Gaudinski, Andrea Lisco, Irini Sereti, Thomas J. Gniadek, Andrea Biondi, Paolo Bonfanti, Luisa Imberti, Clifton L. Dalgard, Yu Zhang, Kerry Dobbs, Helen C. Su, Luigi D. Notarangelo, Colin O. Wu, Peter J. M. Openshaw, Malcolm G. Semple, Ziad Mallat, Kenneth Baillie, Cynthia E. Dunbar, George S. Vassiliou
Journal: Blood
Blood (2022) 140 (14): 1650–1655.
https://doi.org/10.1182/blood.2022015721
Published: 2022
Includes: Supplemental data
Journal Articles

The Longitudinal Dynamics and Natural History of Clonal Hematopoiesis

Margarete A Fabre, Jose Guillherme de Almeida, Edoardo Fiorillo, Emily Mitchell, Aristi Damaskou, Justyna Rak, Valeria Orru, Michele Marongiu, MS Vijayabaskar, Joanna E Baxter, Claire Hardy, Federico Abascal, Michael Spencer Chapman, Nicholas Williams, Jyoti Nangalia, Inigo Martincorena, Peter J Campbell, Eoin F Mckinney, Francesco Cucca, Moritz Gerstung, George S Vassiliou
Journal: Blood
Blood (2021) 138 (Supplement 2): LBA-2.
https://doi.org/10.1182/blood-2021-154938
Published: 2021
Journal Articles

Home and away: clonal hematopoiesis in sibling transplants

Margarete A. Fabre, George S. Vassiliou
Journal: Blood
Blood (2020) 135 (18): 1511–1512.
https://doi.org/10.1182/blood.2020005717
Published: 2020
Journal Articles

Concordance for clonal hematopoiesis is limited in elderly twins

Brief Report
Margarete A. Fabre, Thomas McKerrell, Maximillian Zwiebel, M. S. Vijayabaskar, Naomi Park, Philippa M. Wells, Roland Rad, Panagiotis Deloukas, Kerrin Small, Claire J. Steves, George S. Vassiliou
Journal: Blood
Blood (2020) 135 (4): 269–273.
https://doi.org/10.1182/blood.2019001807
Published: 2020
Includes: Supplemental data