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Journal Articles

Single-Cell Multiomics Reveals a Shared Mechanism of Lineage Switch in DUX4r, ZNF384r, and PAX5 P80R Subtypes of Pediatric Acute Lymphoblastic Leukemia

Vojen Sadílek, Barbora Cabalkova, Aneta Skotnicova, Michaela Reiterova, Martina Vaskova, Marketa Zaliova, Ondrej Hrusak, Jan Trka, Tomas Kalina, Eva Fronkova, Ester Mejstrikova, Jan Stuchly

Blood (2024) 144 (Supplement 1): 635.

https://doi.org/10.1182/blood-2024-209607

Published: 2024

Journal Articles

Somatic Mutations in Cancer-Related Genes Were Observed More Frequently in AYA CML Patients Compared to Elderly at Diagnosis, Whereas the Frequency Was Markedly Higher in Elderly Patients during TKI Treatment

Jitka Krizkova, Vaclava Polivkova, Nikola Curik, Adam Laznicka, Adela Benesova, Hana Klamova, Marketa Stastna Markova, Dana Srbova, Jan Zuna, Marketa Zaliova, Jan Trka, Pavel Semerak, Tomas Kalina, Cyril Salek, Katerina Machova Polakova

Blood (2023) 142 (Supplement 1): 4544.

https://doi.org/10.1182/blood-2023-189017

Published: 2023

Journal Articles

Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling

Daniela Kužílková, PhD, Tomas Kalina, MD PhD, Cristina Bugarin, Dr., Katerina Rejlová, Dr., Daniel Thurner, Dr., Pavel Semerák, Dr., Jan Stuchly, MSc, Andrea Biondi, MD PhD, Giuseppe Gaipa, PhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-141973

Published: 2020

Journal Articles

A homozygous deletion in the SLC19 A1 gene as a cause of folate-dependent recurrent megaloblastic anemia

Michael Svaton, Karolina Skvarova Kramarzova, Veronika Kanderova, Andrea Mancikova, Petr Smisek, Pavel Jesina, Jakub Krijt, Blanka Stiburkova, Robert Dobrovolny, Jitka Sokolova, Violeta Bakardjieva-Mihaylova, Elena Vodickova, Marketa Rackova, Jan Stuchly, Tomas Kalina, Jan Stary, Jan Trka, Eva Fronkova, Viktor Kozich

Blood (2020) 135 (26): 2427–2431.

https://doi.org/10.1182/blood.2019003178

Published: 2020

Includes: Supplemental data

Journal Articles

CD Maps - Dynamic Profiling of CD1 to CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets

Karel Fišer, PhD, Tomas Kalina, MD PhD, Martin Perez-Andres, Daniela Kužílková, PhD, Pablo Engel, Marta Cuenca, PhD, Elena Blanco Álvarez, Sophinus J.W. Bartol, Menno C. van Zelm

Blood (2019) 134 (Supplement_1): 4878.

https://doi.org/10.1182/blood-2019-128123

Published: 2019

Journal Articles

Switching Towards Monocytic Lineage and Discordancy between Flow Cytometric and PCR Minimal Residual Disease Results Is a Hallmark Feature of DUX4 Rearranged B-Cell Precursor Acute Lymphoblastic Leukemia

Michaela Novakova, Barbora Vakrmanova, MD, Lucie Slamova, Alena Musilova, Monika Brüggemann, Matthias Ritgen, MD, Eva Fronkova, MD PhD, Tomas Kalina, MD PhD, Jan Trka, MD PhD, Jan Stary, MD PhD, Martina Vaskova, Lucie Winkowska, Marketa Zaliova, Karel Fišer, PhD, Ondrej Hrusak, Ester Mejstrikova, MD PhD

Blood (2018) 132 (Supplement 1): 2825.

https://doi.org/10.1182/blood-2018-99-116575

Published: 2018

Journal Articles

Folate-Dependent Normocytic Anemia Caused By a Hypomorphic Mutation in SLC19A1 gene

Michael Svaton, MD, Karolina Skvarova Kramarzova, MSc, PhD, Veronika Kanderova, MSc, PhD, Petr Smisek, MD, Pavel Jesina, MSc, MD, PhD, Jakub Krijt, MSc, Blanka Stiburkova, MSc, PhD, Andrea Mancikova, MSc, Robert Dobrovolny, MSc, PhD, Violeta Bakardjieva-Mihaylova, MSc, Elena Vodickova, MD, Jan Stuchly, MSc, Tomas Kalina, MD PhD, Jan Stary, MD PhD, Jan Trka, MD PhD, Eva Fronkova, MD PhD, Viktor Kozich, MD PhD

Blood (2018) 132 (Supplement 1): 502.

https://doi.org/10.1182/blood-2018-99-113501

Published: 2018

Journal Articles

When Standard Markers Are Not Sufficient for Monitoring Minimal Residual Disease or Targeted Treatment: New Transcriptome Derived Flow Cytometry Markers for Switching B Cell Precursor Leukemias

Michaela Novakova, Alena Musilova, Lucie Slamova, Barbora Vakrmanova, Monika Brüggemann, Matthias Ritgen, Eva Fronkova, Tomas Kalina, Ondrej Hrusak, Jan Trka, Jan Stary, Martina Vaskova, Lucie Winkowska, Marketa Zaliova, Karel Fiser, Ester Mejstrikova

Blood (2017) 130 (Supplement 1): 3982.

https://doi.org/10.1182/blood.V130.Suppl_1.3982.3982

Published: 2017

Journal Articles

Multilevel Molecular Profiling to Dissect Resistance to Tyrosine Kinase Inhibitors in TEL/ABL Positive Acute Lymphoblastic Leukemia

Olga Zimmermannova, Veronika Kanderova, Daniela Kuzilkova, Fridtjof Lund-Johansen, Eliska Doktorova, Jiri Petrak, J.H. Frederik Falkenburg, Tomas Kalina, Julia Starkova, Jan Trka, Jan Zuna, Marketa Zaliova

Blood (2014) 124 (21): 3637.

https://doi.org/10.1182/blood.V124.21.3637.3637

Published: 2014

Journal Articles

Potential Involvement of Physiological TCR Gamma Delta Clones in Immune Surveillance of Preleukemic Cells

Olga Zimmermannova, Marketa Zaliova, Anthony V. Moorman, Eva Fronkova, MD, PhD, Jan Stary, Jan Trka, Tomas Kalina, Jan Zuna

Blood (2014) 124 (21): 3775.

https://doi.org/10.1182/blood.V124.21.3775.3775

Published: 2014

Journal Articles

Novel Flow Cytometry-Based Method Of Affinity Proteomics Revealing Expression, Post-Translational Modification and Proteolysis In Primary Childhood Acute Leukemias

Veronika Kanderova, PhD, Daniela Kuzilkova, MSc, Jan Stuchly, MSc, Weiwei Wu, MD, Anders Holm, PhD, Heidi Slåstad, MD, Karel Fiser, Ondrej Hrusak, Fridtjof Lund-Johansen, MD, PhD, Tomas Kalina, MD, PhD

Blood (2013) 122 (21): 2553.

https://doi.org/10.1182/blood.V122.21.2553.2553

Published: 2013

Journal Articles

Epigenetic Changes in CEBPα Gene and Xenotransplantation Model of B Cell Precursor Acute Lymphoblastic Leukemia Switching to Monocytoid Lineage During the Early Phase of the Treatment

Blood (2012) 120 (21): 876.

https://doi.org/10.1182/blood.V120.21.876.876

Published: 2012

Journal Articles

New Targets in Cytometric Investigation of Acute Leukemia Selected From Gene Profiling Studies

Martina Vaskova, PhD, Ester Mejstrikova, MD, PhD, Tomas Brdicka, PhD, Pavla Angelisova, PhD, Tomas Kalina, MD, PhD, Veronika Kanderova, MSc, Daniela Cerna, MSc, Martin Kovac, MSc, Jan Trka, MD, PhD, Fridtjof Lund-Johansen, MD, PhD, Jan Stary, M.D., Ondrej Hrusak, MD., PhD.

Blood (2011) 118 (21): 2536.

https://doi.org/10.1182/blood.V118.21.2536.2536

Published: 2011

Journal Articles

Dual Production of IL-2 and IFN-Gamma by CMV-Specific CD8+ T-Cells Is a Hallmark of Their Ability to Control CMV Reactivation in Patients After Hematopoietic Stem Cell Transplantation,

Tomas Kalina, MD, PhD, Ladislav Krol, MD., Jan Stuchly, MSc., Petra Keslova, MD., Petr Hubacek, MD., Ondrej Pelak, Petr Sedlacek, MD, PhD, Jan Stary, M.D., Ondrej Hrusak, MD., PhD.

Blood (2011) 118 (21): 4081.

https://doi.org/10.1182/blood.V118.21.4081.4081

Published: 2011

Journal Articles

B Precursor ALL Subset with Aberrant CD2 Expression and a Specific Predisposition to Early Monocytic Transdifferentiation

Ester Mejstrikova, MD, PhD, Lucie Slamova, MD, Eva Fronkova, MD, PhD, Jan Zuna, MD, PhD, Jean-Pierre Bourquin, MD, PhD, Elena Vodickova, MD, Katerina Muzikova, Zuzana Zemanova, PhD, Vendula Pelkova, Frederik Van Delft, PhD, Tomas Kalina, MD, PhD, Karel Fiser, PhD, Petr Smisek, MD, Jan Trka, MD, PhD, Jan Stary, MD, DrSc, Ondrej Hrusak, MD, PhD

Blood (2010) 116 (21): 1708.

https://doi.org/10.1182/blood.V116.21.1708.1708

Published: 2010

Journal Articles

Proteomic Analysis of Soluble Proteins Important in Pediatric Acute Lymphoblastic Leukemia.

Martin Kovac, Denisa Petrackova, Vendula Pelkova, Martina Vaskova, Ester Mejstrikova, Tomas Kalina, Petra Volna, Silvie Bezouskova, Jaroslav Weiser, Ondrej Hrusak

Blood (2009) 114 (22): 1448.

https://doi.org/10.1182/blood.V114.22.1448.1448

Published: 2009

Journal Articles

Selected Adaptor Proteins NTAL, LAT, PAG, LIME Function in Proximal Signaling, Corticosteroid Driven Apoptosis and Expression of IKAROS Isoforms in the T-Leukemic Cells.

Karel Svojgr, Tomas Kalina, Tomas Brdicka, Tereza Kacerova, Jana Volejnikova, Jan Stary, Jan Zuna

Blood (2009) 114 (22): 5034.

https://doi.org/10.1182/blood.V114.22.5034.5034

Published: 2009

Journal Articles

NTAL Potentiates Glucocorticosteroid-Induced Apoptosis in T-ALL – in Vivo Observations and Experimental Model

Karel Svojgr, MD, Tatiana Burjanivova, MSc, Martina Vaskova, MSc, PhD, Tomas Kalina, MD, PhD, Tomas Brdicka, PhD, Jan Stary, MD, PhD, Jan Trka, MD, PhD, Jan Zuna, MD, PhD

Blood (2008) 112 (11): 5043.

https://doi.org/10.1182/blood.V112.11.5043.5043

Published: 2008

Journal Articles

Flow Cytometric Detection of BCR-ABL Fusion Proteins in Leukemia Patients Via An Immunobead Assay

Floor Weerkamp, E. Dekking, Vincent H.J. Van der Velden, Sebastian Böttcher, Nancy Boeckx, Elisabeth R. Van Wering, Juan Flores Montero, Paulo Lucio, Lukasz Sedek, Tomas Kalina, Elizabeth Macintyre, Frank J.T. Staal, Jacques JM van Dongen, Ph.D

Blood (2008) 112 (11): 2533.

https://doi.org/10.1182/blood.V112.11.2533.2533

Published: 2008

Journal Articles

Expression of Transmembrane Adaptors Is Specific in Distinct Childhood Acute Lymphoblastic Leukaemia Subgroups and Indicates Early Treatment Response in T-ALL.

Karel Svojgr, Tatiana Burjanivova, Martina Vaskova, Tomas Kalina, Jan Stary, Jan Trka, Jan Zuna

Blood (2007) 110 (11): 1433.

https://doi.org/10.1182/blood.V110.11.1433.1433

Published: 2007

NARROW

Single-Cell Multiomics Reveals a Shared Mechanism of Lineage Switch in DUX4r, ZNF384r, and PAX5 P80R Subtypes of Pediatric Acute Lymphoblastic Leukemia

Somatic Mutations in Cancer-Related Genes Were Observed More Frequently in AYA CML Patients Compared to Elderly at Diagnosis, Whereas the Frequency Was Markedly Higher in Elderly Patients during TKI Treatment

Single-Cell Profiling of Signal Transduction Pathways in Pediatric T-Cell Acute Lymphoblastic Leukemia By Mass Cytometry:Dissecting JAK/STAT and PI3K/Akt/mTOR Active Signalling

A homozygous deletion in the SLC19 A1 gene as a cause of folate-dependent recurrent megaloblastic anemia

CD Maps - Dynamic Profiling of CD1 to CD100 Surface Expression on Human Leukocyte and Lymphocyte Subsets

Switching Towards Monocytic Lineage and Discordancy between Flow Cytometric and PCR Minimal Residual Disease Results Is a Hallmark Feature of DUX4 Rearranged B-Cell Precursor Acute Lymphoblastic Leukemia

Folate-Dependent Normocytic Anemia Caused By a Hypomorphic Mutation in SLC19A1 gene

When Standard Markers Are Not Sufficient for Monitoring Minimal Residual Disease or Targeted Treatment: New Transcriptome Derived Flow Cytometry Markers for Switching B Cell Precursor Leukemias

Multilevel Molecular Profiling to Dissect Resistance to Tyrosine Kinase Inhibitors in TEL/ABL Positive Acute Lymphoblastic Leukemia

Potential Involvement of Physiological TCR Gamma Delta Clones in Immune Surveillance of Preleukemic Cells

Novel Flow Cytometry-Based Method Of Affinity Proteomics Revealing Expression, Post-Translational Modification and Proteolysis In Primary Childhood Acute Leukemias

Epigenetic Changes in CEBPα Gene and Xenotransplantation Model of B Cell Precursor Acute Lymphoblastic Leukemia Switching to Monocytoid Lineage During the Early Phase of the Treatment

New Targets in Cytometric Investigation of Acute Leukemia Selected From Gene Profiling Studies

Dual Production of IL-2 and IFN-Gamma by CMV-Specific CD8+ T-Cells Is a Hallmark of Their Ability to Control CMV Reactivation in Patients After Hematopoietic Stem Cell Transplantation,

B Precursor ALL Subset with Aberrant CD2 Expression and a Specific Predisposition to Early Monocytic Transdifferentiation

Proteomic Analysis of Soluble Proteins Important in Pediatric Acute Lymphoblastic Leukemia.

Selected Adaptor Proteins NTAL, LAT, PAG, LIME Function in Proximal Signaling, Corticosteroid Driven Apoptosis and Expression of IKAROS Isoforms in the T-Leukemic Cells.

NTAL Potentiates Glucocorticosteroid-Induced Apoptosis in T-ALL – in Vivo Observations and Experimental Model

Flow Cytometric Detection of BCR-ABL Fusion Proteins in Leukemia Patients Via An Immunobead Assay

Expression of Transmembrane Adaptors Is Specific in Distinct Childhood Acute Lymphoblastic Leukaemia Subgroups and Indicates Early Treatment Response in T-ALL.

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American Society of Hematology

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American Society of Hematology

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