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Journal Articles

Memory CD4 + T Cells Recognize Divergent HLA-DP Immunopeptidomes and Contribute to Leukemia Control after Allogeneic HCT

Blood (2024) 144 (Supplement 1): 901.

https://doi.org/10.1182/blood-2024-210787

Published: 2024

Journal Articles

T-Cell Monitoring for the Recently Expanded Repertoire of HLA Class I-Restricted Minor Histocompatibility Antigens Using Barcoded Peptide-MHC Multimers

Kyra J. Fuchs, Marcus Göransson, Michel G.D. Kester, Natasja W. Ettienne, Marian van de Meent, Rob C.M. de Jong, Eva A.S. Koster, Constantijn J.M. Halkes, Ferenc A. Scheeren, Mirjam H.M. Heemskerk, Peter Van Balen, J.H. Frederik Falkenburg, Sine R. Hadrup, Marieke Griffioen

Blood (2024) 144 (Supplement 1): 691.

https://doi.org/10.1182/blood-2024-197955

Published: 2024

Journal Articles

Randomized Trial of Prophylactic Donor Lymphocyte Infusion with Positively Selected CD4+ T Cells after HLA-Identical Allogeneic Stem Cell Transplantation

Joost Van Der Hem, Peter Van Balen, Sabrina Veld, Peter A. Von Dem Borne, Danielle Van Lammeren, Tjeerd Snijders, Jaap Jan Zwaginga, Hendrik Veelken, Rosa De Groot, Inge Jedema, Liesbeth C. de Wreede, Constantijn Halkes, J.H. Frederik Falkenburg

Blood (2023) 142 (Supplement 1): 6887.

https://doi.org/10.1182/blood-2023-188843

Published: 2023

Journal Articles

T Cell Receptor-Based Targeting of Immunoglobulin Constant Domains for Treatment of Multiple Myeloma

Miranda H. Meeuwsen, Anne K. Wouters, Tassilo L.A. Wachsmann, Renate S. Hagedoorn, Dennis F.G. Remst, Michel G.D. Kester, Dirk M. van der Steen, Arnoud H. de Ru, Peter A. van Veelen, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

Blood (2022) 140 (Supplement 1): 10292–10293.

https://doi.org/10.1182/blood-2022-170314

Published: 2022

Journal Articles

Large Scale Identification and Validation of 85 New HLA Class I-Restricted Minor Histocompatibility Antigens for Immune Monitoring and Modulation after Allogeneic Stem Cell Transplantation

Kyra J. Fuchs, M. Willy Honders, Marian van de Meent, Indu Khatri, Eva A.S. Koster, Cornelis A.M. van Bergen, Erik B. van den Akker, Constantijn J.M. Halkes, J.H. Frederik Falkenburg, Marieke Griffioen

Blood (2022) 140 (Supplement 1): 10196–10197.

https://doi.org/10.1182/blood-2022-157938

Published: 2022

Journal Articles

Broadly Applicable TCR Based Therapy for Multiple Myeloma Targeting the Jchain

Miranda H. Meeuwsen, Anne K. Wouters, Tassilo L.A. Wachsmann, Renate S. Hagedoorn, Michel G.D. Kester, Dennis F.G. Remst, Dirk M. van der Steen, Arnoud H. de Ru, Els P. van Hees, Marieke Griffioen, Peter A. van Veelen, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

Blood (2022) 140 (Supplement 1): 4498–4499.

https://doi.org/10.1182/blood-2022-156923

Published: 2022

Journal Articles

Sars-Cov-2-Specific CD4 + and CD8 + T Cell Responses Can Originate from Cross-Reactive CMV-Specific T Cells

Cilia R. Pothast, Romy C. Dijkland, Melissa Thaler, Renate S. Hagedoorn, Michel G.D. Kester, Anne K. Wouters, Pieter S. Hiemstra, Martijn J. van Hemert, Stephanie Gras, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

Blood (2022) 140 (Supplement 1): 2631–2632.

https://doi.org/10.1182/blood-2022-156715

Published: 2022

Journal Articles

Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas

Wesley Huisman, MSc, Lieve E. van der Maarel, Lois Hageman, Rob C.M. de Jong, Derk Amsen, PhD, J.H. Frederik Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2018) 132 (Supplement 1): 1578.

https://doi.org/10.1182/blood-2018-99-116127

Published: 2018

Journal Articles

Prophylactic Infusion of Multi-Antigen Specific T-Cell Products to Prevent Complications after T Cell Depleted Allogeneic Stem Cell Transplantation — a Phase I/II Study

Marthe C.J. Roex, MD, Peter van Balen, MD, Lothar Germeroth, PhD, Lois Hageman, Esther van Egmond, Sabrina A.J. Veld, Conny Hoogstraten, Ellis van Liempt, PhD, Jaap J. Zwaginga, MD PhD, Liesbeth C. de Wreede, PhD, Hermann Einsele, MD PhD, Hendrik Veelken, MD PhD, Constantijn J.M. Halkes, MD, Inge Jedema, PhD, J.H. Frederik Falkenburg, MD PhD

Blood (2018) 132 (Supplement 1): 119.

https://doi.org/10.1182/blood-2018-99-111749

Published: 2018

Journal Articles

First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

Moniek De Witte, MD PhD, Anna Van Rhenen, MD PhD, Geerte Van Sluis, MD PhD, Rick Admiraal, MD PhD, Lotte van der Wagen, MD, Eefke J. Petersen, MD PhD, Reinier Raymakers, MD PhD, Monique C Minnema, MD PhD, Anke Janssen, MD, Kasper Westinga, BSc, Constantijn J.M. Halkes, MD, J.H. Frederik Falkenburg, MD PhD, Jaap Jan Boelens, MD PhD, Jurgen Kuball, MD

Blood (2018) 132 (Supplement 1): 2164.

https://doi.org/10.1182/blood-2018-99-112758

Published: 2018

Journal Articles

Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease

Eva AS Koster, MD, Liesbeth C. de Wreede, PhD, Sylwia Wallet-Malicka, Lisette Bogers, Peter van Balen, MD, Waf Marijt, MD, Inge Jedema, PhD, Peter von dem Borne, MD PhD, Hendrik Veelken, MD PhD, J.H. Frederik Falkenburg, MD PhD, Constantijn J.M. Halkes, MD

Blood (2018) 132 (Supplement 1): 2132.

https://doi.org/10.1182/blood-2018-99-113839

Published: 2018

Journal Articles

The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity

Wesley Huisman, MSc, Didier A.T. Leboux, Lieve E. van der Maarel, Lois Hageman, Derk Amsen, PhD, J.H. Frederik Falkenburg, MD PhD, Inge Jedema, PhD

Blood (2018) 132 (Supplement 1): 2048.

https://doi.org/10.1182/blood-2018-99-116028

Published: 2018

Journal Articles

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Dyantha I. Van Der Lee, BSc., Helena M. Bijen, MSc, Renate S. Hagedoorn, ing., Willy M. Honders, ing., Michel G.D. Kester, ing., Dirk M. van der Steen, ing., Arnoud H. de Ru, ing., Inge Jedema, PhD, Hendrik Veelken, MD PhD, Mirjam H.M. Heemskerk, PhD, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Marieke Griffioen, PhD

Blood (2017) 130 (Supplement 1): 168.

https://doi.org/10.1182/blood.V130.Suppl_1.168.168

Published: 2017

Journal Articles

Prevention of Viral Infections after T Cell Depleted Allogeneic Stem Cell Transplantation By Infusion of Multi-Antigen Specific T Cell Products

Marthe C.J. Roex, MD, Peter Van Balen, MD, Lois Hageman, Esther Van Egmond, Sabrina A.J. Veld, Conny Hoogstraten, Ellis van Liempt, PhD, Lothar Germeroth, PhD, Hermann Einsele, MD, Constantijn J.M. Halkes, MD PhD, Inge Jedema, PhD, J.H. Frederik Falkenburg, MD PhD

Blood (2016) 128 (22): 1228.

https://doi.org/10.1182/blood.V128.22.1228.1228

Published: 2016

Journal Articles

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

Cornelis A.M. van Bergen, PhD, Dirk M. van der Steen, Michel G.D. Kester, Marvyn T. Koning, BSc, Peter A. van Veelen, PhD, Marieke Griffioen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD, Hendrik Veelken, MD PhD, Marcelo A Navarrete, MD PhD

Blood (2016) 128 (22): 914.

https://doi.org/10.1182/blood.V128.22.914.914

Published: 2016

Journal Articles

The Allo-HLA-DP Restricted T Cell Repertoire Contains a Variety of Tissue-Restricted Specificities with Therapeutic Value

Aicha Laghmouchi, Conny Hoogstraten, Peter Van Balen, MD, Rick van de Water, Marian van de Meent, J.H. Frederik Falkenburg, Prof, MD PhD, Inge Jedema, PhD

Blood (2016) 128 (22): 3356.

https://doi.org/10.1182/blood.V128.22.3356.3356

Published: 2016

Journal Articles

Early CD4+ T-Cell Effector Alloreactivity Towards Multiple Mismatched HLA Class II Alleles Is Associated with Graft Predominance after Double Umbilical Cord Blood Transplantation (dUCBT)

Jan J. Cornelissen, MD PhD, Rebecca Wijers, Cornelis A.M. van Bergen, Judith Somers, MD, Eric Braakman, PhD, Jan W. Gratama, MD PhD, Reno Debets, PhD, J.H. Frederik Falkenburg, MD PhD, Cor Lamers

Blood (2015) 126 (23): 387.

https://doi.org/10.1182/blood.V126.23.387.387

Published: 2015

Journal Articles

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

Lorenz Jahn, Renate S. Hagedoorn, Pleun Hombrink, PhD, Michel G.D. Kester, Dirk M. van der Steen, Chopie Hassan, Marjolein P. Schoonakker, Erwin van der Pijl, Peter A. van Veelen, PhD, J.H. Frederik Falkenburg, MD PhD, Mirjam H.M. Heemskerk, PhD

Blood (2015) 126 (23): 3002.

https://doi.org/10.1182/blood.V126.23.3002.3002

Published: 2015

Journal Articles

A Polyclonal Population of Piga Mutant CD52 and GPI Anchor Negative T Cells Can Give Early Immune Protection after Alemtuzumab-Based T Cell Depleted Allogeneic Stem Cell Transplantation

Floris C. Loeff, J.H. Frederik Falkenburg, MD PhD, Lois Hageman, Sabrina A.J. Veld, Marian van de Meent, Constantijn J.M. Halkes, MD PhD, Inge Jedema, PhD

Blood (2015) 126 (23): 3134.

https://doi.org/10.1182/blood.V126.23.3134.3134

Published: 2015

Journal Articles

Characterization of Leukemias with ETV6-ABL1 Fusion

Blood (2015) 126 (23): 84.

https://doi.org/10.1182/blood.V126.23.84.84

Published: 2015

NARROW

Memory CD4 + T Cells Recognize Divergent HLA-DP Immunopeptidomes and Contribute to Leukemia Control after Allogeneic HCT

T-Cell Monitoring for the Recently Expanded Repertoire of HLA Class I-Restricted Minor Histocompatibility Antigens Using Barcoded Peptide-MHC Multimers

Randomized Trial of Prophylactic Donor Lymphocyte Infusion with Positively Selected CD4+ T Cells after HLA-Identical Allogeneic Stem Cell Transplantation

T Cell Receptor-Based Targeting of Immunoglobulin Constant Domains for Treatment of Multiple Myeloma

Large Scale Identification and Validation of 85 New HLA Class I-Restricted Minor Histocompatibility Antigens for Immune Monitoring and Modulation after Allogeneic Stem Cell Transplantation

Broadly Applicable TCR Based Therapy for Multiple Myeloma Targeting the Jchain

Sars-Cov-2-Specific CD4 + and CD8 + T Cell Responses Can Originate from Cross-Reactive CMV-Specific T Cells

Isolation and Validation of the First Functional HLA-a*01:01 Restricted EBV-LMP2 Specific T Cells for Treatment of EBV Associated Type II/III Lymphomas

Prophylactic Infusion of Multi-Antigen Specific T-Cell Products to Prevent Complications after T Cell Depleted Allogeneic Stem Cell Transplantation — a Phase I/II Study

First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

Patient Bone Marrow Chimerism at Time of Donor Lymphocyte Infusion Predicts Development of Graft Versus Host Disease

The Scope of Allo-HLA Cross-Reactivity By (Third Party) Virus Specific T Cells Is Surprisingly Affected By HLA Restriction Rather Than Virus Specificity

Mutated NPM1 As Target for Immunotherapy of Acute Myeloid Leukemia

Prevention of Viral Infections after T Cell Depleted Allogeneic Stem Cell Transplantation By Infusion of Multi-Antigen Specific T Cell Products

Endogenous Immunoglobulin-Derived Neoepitopes Are Processed and Form a Sizeable Fraction of the HLA Class I Ligandome of Human Lymphoma Cells

The Allo-HLA-DP Restricted T Cell Repertoire Contains a Variety of Tissue-Restricted Specificities with Therapeutic Value

Early CD4+ T-Cell Effector Alloreactivity Towards Multiple Mismatched HLA Class II Alleles Is Associated with Graft Predominance after Double Umbilical Cord Blood Transplantation (dUCBT)

T Cell Receptor Gene Therapy Targeting the Intracellular Transcription Factor Bob1 for the Treatment of Multiple Myeloma and Other B Cell Malignancies

A Polyclonal Population of Piga Mutant CD52 and GPI Anchor Negative T Cells Can Give Early Immune Protection after Alemtuzumab-Based T Cell Depleted Allogeneic Stem Cell Transplantation

Characterization of Leukemias with ETV6-ABL1 Fusion

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American Society of Hematology

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American Society of Hematology

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