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Journal Articles

Targeting of Various Inflammatory Circuits Does Not Ameliorate Ineffective Hematopoiesis: Results of the Lucas and Canfire Studies Investigating IRAK4 or IL-1β Blockade to Target Anemia in Lower-Risk MDS

Anne Sophie Kubasch, Katharina Zoldan, Michael Cross, Marie Schneider, Jens Przybilla, Dirk Hasenclever, Klaus H Metzeler, Uwe Platzbecker

Blood (2024) 144 (Supplement 1): 3221.

https://doi.org/10.1182/blood-2024-199032

Published: 2024

Journal Articles

Mutant Idh1 Blocks Neutrophil Maturation By Repressing Myeloid Progenitor Programs

Blood (2024) 144 (Supplement 1): 1341.

https://doi.org/10.1182/blood-2024-210352

Published: 2024

Journal Articles

Activation of Distinct Inflammatory Pathways in LR-MDS Is Determined By Genetics

Marie Schneider, Clara Rolfs, Matthias Trumpp, Susann Winter, Luise Fischer, Mandy Richter, Victoria Menger, Kolja Nenoff, Nora Grieb, Anne Sophie Kubasch, Klaus H. Metzeler, Katja Sockel, Christian Thiede, Lorenz C Hofbauer, Andreas Roth, Andreas Bruederle, Janghee Woo, Michael Cross, Uwe Platzbecker

Blood (2022) 140 (Supplement 1): 4011–4012.

https://doi.org/10.1182/blood-2022-163246

Published: 2022

Journal Articles

Incidence, Risk Factors, Treatment and Long Term Outcome of Refractory and First Relapse AML Patients in the OSHO Studies

Blood (2019) 134 (Supplement_1): 1358.

https://doi.org/10.1182/blood-2019-125262

Published: 2019

Journal Articles

Impact of Somatic Mutations on Outcome in Patients > 60 Years Old with Newly Diagnosed AML Treated with Response-Adapted Sequential Azacitidine and Induction Chemotherapy within the DRKS00004519 Trial (RAS-AZIC) of the East German Study Group of Hematology and Oncology (OSHO)

Nadja Jaekel, Susann Schulze, MD, Udo Siebolts, MD, Anja Haak, PhD, Nikolaos Pazaitis, MD, Michael Cross, PhD, Dietger Niederwieser, MD, Mathias Hänel, MD, Georg Maschmeyer, MD, Maxi Wass, MD, Lukas Heukamp, MB PhD, Roopika Menon, Miriam Bertrand, Claudia Wickenhauser, MD, Oana Brosteanu, PhD, Haifa Kathrin Al-Ali, MD

Blood (2019) 134 (Supplement_1): 1420.

https://doi.org/10.1182/blood-2019-127865

Published: 2019

Journal Articles

Phase II Study of Stimulation of Healthy Sibling Donors with Single-Shot Pegfilgrastim - Update (EUDRACT Nr: 2005-004971-39)

Vladan Vucinic, MD, Sabine Leiblein, PhD, Kristina Schakols, MD, Claudia Nehring, MD, Yvonne Remane, PhD, Madlen Jentzsch, MD, Sebastian Schwind, MD, Wolfram Pönisch, MD, Runa Stiegler, MD, Constanze Kliem, MD, Michael Cross, PhD, Dietger Niederwieser, MD

Blood (2018) 132 (Supplement 1): 2064.

https://doi.org/10.1182/blood-2018-99-118531

Published: 2018

Journal Articles

Reduction of Immunosuppression after Disease-Specific Donor Cell Chimerism Decrease Can Prevent Hematological Relapse Following Allogeneic Stem Cell Transplantation after Non-Myeloablative (NMA) Conditioning — Results of a Prospective Phase II Study. Eudract #: 2007-002420-15

Vladan Vucinic, Saskia Hell, Madlen Jentzsch, MD, Michael Cross, PhD, Sabine Leiblein, Wolfram Pönisch, MD, Georg-Nikolaus Franke, MD, Gerhard Behre, MD, Thoralf Lange, MD, Sebastian Schwind, MD, Dietger Niederwieser, MD

Blood (2017) 130 (Supplement 1): 3230.

https://doi.org/10.1182/blood.V130.Suppl_1.3230.3230

Published: 2017

Journal Articles

Prognostic Impact of Clonal Hematopoiesis in Acute Myeloid Leukemia Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation in Complete Remission

Juliane Grimm, Marius Bill, PhD, Madlen Jentzsch, MD, Stefanie Beinicke, MSc, Janine Häntschel, MSc, Karoline Goldmann, Julia Schulz, Michael Cross, PhD, Wolfram Pönisch, MD, Vladan Vucinic, Gerhard Behre, MD, Thoralf Lange, MD, Georg-Nikolaus Franke, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2017) 130 (Supplement 1): 406.

https://doi.org/10.1182/blood.V130.Suppl_1.406.406

Published: 2017

Journal Articles

In AML RAS pathway Mutations Confer Worse Outcome in IDH1 and IDH2 Mutated AML Patients Receiving Hematopoietic Stem Cell Transplantation

Stefanie Beinicke, MSc, Juliane Grimm, Madlen Jentzsch, MD, Marius Bill, PhD, Janine Häntschel, MSc, Karoline Goldmann, Julia Schulz, Michael Cross, PhD, Georg-Nikolaus Franke, MD, Vladan Vucinic, Wolfram Pönisch, MD, Gerhard Behre, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2017) 130 (Supplement 1): 2037.

https://doi.org/10.1182/blood.V130.Suppl_1.2037.2037

Published: 2017

Journal Articles

Incidence of Low Level Mutations in Newly Diagnosed CML Patients: A Substudy of the German Tiger Trial

Georg-Nikolaus Franke, MD, Jacqueline Maier, PhD, Kathrin Wildenberger, Christine Günther, Michael Cross, PhD, Thomas Ernst, MD, Christian Fabisch, PhD, Dietger Niederwieser, MD, Andreas Hochhaus, MD, Thoralf Lange, MD

Blood (2017) 130 (Supplement 1): 252.

https://doi.org/10.1182/blood.V130.Suppl_1.252.252

Published: 2017

Journal Articles

Response-Adapted Sequential Treatment with Azacitidine and Intensive Chemotherapy in Patients > 60 Years Old with Newly Diagnosed AML: Results of the RAS-Azic Trial of the East German Study Group (OSHO)

Nadia Jaekel, MD, Karolin Hubert, Rainer Krahl, PhD, M Haenel, MD, Georg Maschmeyer, MD, Regina Herbst, MD, Christian Jakob, MD, Susann Schulze, Song-Yau Wang, Michael Cross, PhD, Christoph Kahl, MD, Maxi Wass, MD, Herbert G. Sayer, MD PhD, Oana Brosteanu, PhD, Dietger Niederwieser, MD, Haifa Kathrin Al-Ali

Blood (2017) 130 (Supplement 1): 1334.

https://doi.org/10.1182/blood.V130.Suppl_1.1334.1334

Published: 2017

Journal Articles

High Expression of the DNMT3A Embedded Pri- Mir -1301 Associates with Improved Outcome in Patients with Acute Myeloid Leukemia

Janine Häntschel, MSc, Madlen Jentzsch, MD, Juliane Grimm, Marius Bill, Stefanie Beinicke, MSc, Laura K. Schmalbrock, MD, Lynn Bonifacio, MD, Luba Schuhmann, Julia Schulz, Karoline Goldmann, Michael Cross, PhD, Georg-Nikolaus Franke, MD, Vladan Vucinic, Wolfram Pönisch, MD, Gerhard Behre, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2017) 130 (Supplement 1): 1203.

https://doi.org/10.1182/blood.V130.Suppl_1.1203.1203

Published: 2017

Journal Articles

High Expression of ZBTB7A at Diagnosis Associated with Inferior Outcome in Acute Myeloid Leukemia Patients Receiving Hematopoietic Stem Cell Transplantation

Juliane Grimm, Madlen Jentzsch, MD, Marius Bill, MD PhD, Julia Schulz, Karoline Schubert, Stefanie Beinicke, Janine Haentschel, Luba Schuhmann, Michael Cross, PhD, Vladan Vucinic, MD, Wolfram Poenisch, MD, Gerhard Behre, MD, Georg-Nikolaus Franke, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2016) 128 (22): 5092.

https://doi.org/10.1182/blood.V128.22.5092.5092

Published: 2016

Journal Articles

Biological Associations and Clinical Impact of Differential Expression of the Pre- Mir-29a/b-1 and P re -Mir-29b-2/C Clusters in Acute Myeloid Leukemia

Florian Ramdohr, MD, Marius Bill, MD PhD, Madlen Jentzsch, MD, Karoline Schubert, Juliane Grimm, Julia Schulz, Luba Schuhmann, Laura Katharina Schmalbrock, MD, Lynn Baquiran Bonifacio, MD, Stefanie Beinicke, Janine Haentschel, Wolfram Poenisch, MD, Vladan Vucinic, MD, Georg-Nikolaus Franke, MD, Thoralf Lange, MD, Michael Cross, PhD, Gerhard Behre, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2016) 128 (22): 5110.

https://doi.org/10.1182/blood.V128.22.5110.5110

Published: 2016

Journal Articles

Increasing the Sensitivity of BCR-ABL Monitoring By Digital PCR By Reducing the Background Noise

Georg-Nikolaus Franke, MD, Jacqueline Maier, PhD, Svilen Tzonev, PhD, Dawne Naomi Shelton, PhD, Michael Cross, PhD, Kathrin Wildenberger, Dietger Niederwieser, MD, Thoralf Lange, MD

Blood (2016) 128 (22): 3085.

https://doi.org/10.1182/blood.V128.22.3085.3085

Published: 2016

Journal Articles

High Expression of the Hedgehog Transcription Factor GLI1 Is Associated with Improved Outcomes in Patients with Acute Myeloid Leukemia Undergoing Hematopoietic Stem Cell Transplantation after Non-Myeloablative Conditioning

Marius Bill, MDPhD, Madlen Jentzsch, MD, Luba Schuhmann, Juliane Grimm, Maria Knyrim, Laura Katharina Schmalbrock, MD, Schubert Karoline, Michael Cross, PhD, Vladan Vucinic, MD, Georg-Nikolaus Franke, MD, Wolfram Poenisch, MD, Gerhard Behre, MD, Thoralf Lange, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2015) 126 (23): 2032.

https://doi.org/10.1182/blood.V126.23.2032.2032

Published: 2015

Journal Articles

Quantification of BCR-ABL with Digital PCR Results in a Significantly Lower Rate of Deep Molecular Responses When Compared to RT-qPCR in CML Patients Treated in the ENEST1st Trial

Georg-Nikolaus Franke, MD, Jacqueline Maier, PhD, Kathrin Wildenberger, Michael Cross, PhD, Oliver Frank, PhD, Frank Giles, MDMB, Andreas Hochhaus, MD, Christian T. Dietz, PhD, Martin C. Müller, Dietger Niederwieser, MD, Thoralf Lange, MD

Blood (2015) 126 (23): 135.

https://doi.org/10.1182/blood.V126.23.135.135

Published: 2015

Journal Articles

Higher Incidence of Secondary AML and Adverse Molecular Markers, Together with Lower CR and Higher AML Related Death Rates in Elderly Compared to Younger Patients: Results from 2435 Patients Included in the Two German AML Intergroup Studies

Blood (2015) 126 (23): 2517.

https://doi.org/10.1182/blood.V126.23.2517.2517

Published: 2015

Journal Articles

Next Generation Sequencing and Functional Analysis of Mirna Expression in Acute Myeloid Leukemia Patients with Different FLT3 Mutations: Block of MiR-155 in FLT3-ITD Driven AML Leads to Downregulation of Myeloid Blasts in Vivo

Dennis Gerloff, Alexander Arthur Wurm, Jens-Uwe Hartmann, Nadja Hilger, Anne-Marie Müller, Christiane Katzerke, PhD, Daniela Bräuer-Hartmann, Carolina Yaeko Namasu, MSc, Michael Cross, PhD, Sebastian Schwind, MD, Knut Krohn, PhD, Stephan Fricke, MD, Dietger Niederwieser, MD, Gerhard Behre, MD

Blood (2015) 126 (23): 2438.

https://doi.org/10.1182/blood.V126.23.2438.2438

Published: 2015

Journal Articles

Unsupervised Cluster Analysis of Antigen Expression Patterns Identifies Subgroups with Distinct Biological and Clinical Features in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation

Madlen Jentzsch, MD, Luba Schuhmann, Marius Bill, MDPhD, Sabine Leiblein, PhD, Ulrike Bergmann, Martina Pless, Karoline Schubert, Laura Katharina Schmalbrock, MD, Juliane Grimm, Maria Knyrim, Wolfram Poenisch, MD, Georg-Nikolaus Franke, MD, Vladan Vucinic, MD, Michael Cross, PhD, Gerhard Behre, MD, Dietger Niederwieser, MD, Sebastian Schwind, MD

Blood (2015) 126 (23): 2573.

https://doi.org/10.1182/blood.V126.23.2573.2573

Published: 2015

NARROW

Targeting of Various Inflammatory Circuits Does Not Ameliorate Ineffective Hematopoiesis: Results of the Lucas and Canfire Studies Investigating IRAK4 or IL-1β Blockade to Target Anemia in Lower-Risk MDS

Mutant Idh1 Blocks Neutrophil Maturation By Repressing Myeloid Progenitor Programs

Activation of Distinct Inflammatory Pathways in LR-MDS Is Determined By Genetics

Incidence, Risk Factors, Treatment and Long Term Outcome of Refractory and First Relapse AML Patients in the OSHO Studies

Impact of Somatic Mutations on Outcome in Patients > 60 Years Old with Newly Diagnosed AML Treated with Response-Adapted Sequential Azacitidine and Induction Chemotherapy within the DRKS00004519 Trial (RAS-AZIC) of the East German Study Group of Hematology and Oncology (OSHO)

Phase II Study of Stimulation of Healthy Sibling Donors with Single-Shot Pegfilgrastim - Update (EUDRACT Nr: 2005-004971-39)

Reduction of Immunosuppression after Disease-Specific Donor Cell Chimerism Decrease Can Prevent Hematological Relapse Following Allogeneic Stem Cell Transplantation after Non-Myeloablative (NMA) Conditioning — Results of a Prospective Phase II Study. Eudract #: 2007-002420-15

Prognostic Impact of Clonal Hematopoiesis in Acute Myeloid Leukemia Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation in Complete Remission

In AML RAS pathway Mutations Confer Worse Outcome in IDH1 and IDH2 Mutated AML Patients Receiving Hematopoietic Stem Cell Transplantation

Incidence of Low Level Mutations in Newly Diagnosed CML Patients: A Substudy of the German Tiger Trial

Response-Adapted Sequential Treatment with Azacitidine and Intensive Chemotherapy in Patients > 60 Years Old with Newly Diagnosed AML: Results of the RAS-Azic Trial of the East German Study Group (OSHO)

High Expression of the DNMT3A Embedded Pri- Mir -1301 Associates with Improved Outcome in Patients with Acute Myeloid Leukemia

High Expression of ZBTB7A at Diagnosis Associated with Inferior Outcome in Acute Myeloid Leukemia Patients Receiving Hematopoietic Stem Cell Transplantation

Biological Associations and Clinical Impact of Differential Expression of the Pre- Mir-29a/b-1 and P re -Mir-29b-2/C Clusters in Acute Myeloid Leukemia

Increasing the Sensitivity of BCR-ABL Monitoring By Digital PCR By Reducing the Background Noise

High Expression of the Hedgehog Transcription Factor GLI1 Is Associated with Improved Outcomes in Patients with Acute Myeloid Leukemia Undergoing Hematopoietic Stem Cell Transplantation after Non-Myeloablative Conditioning

Quantification of BCR-ABL with Digital PCR Results in a Significantly Lower Rate of Deep Molecular Responses When Compared to RT-qPCR in CML Patients Treated in the ENEST1st Trial

Higher Incidence of Secondary AML and Adverse Molecular Markers, Together with Lower CR and Higher AML Related Death Rates in Elderly Compared to Younger Patients: Results from 2435 Patients Included in the Two German AML Intergroup Studies

Next Generation Sequencing and Functional Analysis of Mirna Expression in Acute Myeloid Leukemia Patients with Different FLT3 Mutations: Block of MiR-155 in FLT3-ITD Driven AML Leads to Downregulation of Myeloid Blasts in Vivo

Unsupervised Cluster Analysis of Antigen Expression Patterns Identifies Subgroups with Distinct Biological and Clinical Features in Patients with Acute Myeloid Leukemia Undergoing Allogeneic Stem Cell Transplantation

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American Society of Hematology

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American Society of Hematology

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