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Journal Articles

Chromatin-Based Cellular Dependency of HOXA9/MEIS1-Driven Acute Myeloid Leukemia

Federica Valigi, Fulya Mina Kücüktas, Ilya Fliamer, Zivojin Jevtic, Hughes-Etienne Chatel-Soulet, Amandine Bovay, Rathick Sivalingam, Andreja Baosic, Florian Grebien, Robert K. Slany, Alexandar Tzankov, Sabine Juge, Jonathan Seguin, Menghan Wang, Athimed El Taher, Luca Giorgetti, Juerg Schwaller
Journal: Blood
Blood (2024) 144 (Supplement 1): 2729.
https://doi.org/10.1182/blood-2024-207011
Published: 2024
Journal Articles

The NFIA-ETO2 fusion blocks erythroid maturation and induces pure erythroid leukemia in cooperation with mutant TP53

Maria-Riera Piqué-Borràs, Zivojin Jevtic, Frederik Otzen Bagger, Jonathan Seguin, Rathick Sivalingam, Matheus Filgueira Bezerra, Amber Louwagie, Sabine Juge, Ioannis Nellas, Robert Ivanek, Alexandar Tzankov, Ute M. Moll, Oriano Cantillo, Ramona Schulz-Heddergott, Alexandre Fagnan, Thomas Mercher, Juerg Schwaller
Journal: Blood
Blood (2023) 141 (18): 2245–2260.
https://doi.org/10.1182/blood.2022017273
Published: 2023
Includes: Supplemental data
Journal Articles

Modeling the Cellular Origin of EVI1 + MLL-AF9-Driven Acute Myeloid Leukemia (AML)

Hugues-Etienne Chatel-Soulet, Sabine Juge, Frederik Otzen Bagger, Alexandar Tzankov, Mineo Kurokawa, Jonathan Séguin, Juerg Schwaller
Journal: Blood
Blood (2021) 138 (Supplement 1): 2210.
https://doi.org/10.1182/blood-2021-149439
Published: 2021
Journal Articles

Transformation Mechanisms of the Nfia -ETO2 Fusion Gene Associated with Pediatric Pure Acute Erythroleukemia

Maria-Riera Piqué-Borràs, Msc, Frederik Otzen Bagger, PhD, Matheus Filgueira Bezerra, MSc, Amber Louwaige, Msc, Sabine Juge, Ioannis Nellas, Msc, Robert Ivanek, PhD, Alexandar Tzankov, MD, Ute M Moll, MD, Ramona Schulz-Heddergott, PhD, Thomas Mercher, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 532.
https://doi.org/10.1182/blood-2019-126416
Published: 2019
Journal Articles

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

Sara El Ashkar, Juerg Schwaller, Tim Pieters, Steven Goossens, Jonas Demeulemeester, Frauke Christ, Siska Van Belle, Sabine Juge, Nancy Boeckx, Alan Engelman, Pieter Van Vlierberghe, Zeger Debyser, Jan De Rijck
Journal: Blood
Blood (2018) 131 (1): 95–107.
https://doi.org/10.1182/blood-2017-05-786962
Published: 2018
Includes: Supplemental data
Journal Articles

Fetal Inactivation of the Nuclear Interacting SET Domain Protein 1 Impairs Terminal Erythroid Maturation and Results in Acute Erythroleukemia in Mice

Katharina Leonards, PhD, Marwa Almosailleakh, MSc, Samantha Tauchmann, Msc, Helene Mereau, PhD, Sabine Juge, Matheus Filgueira Bezerra, MSc, Susanne Kasper, PhD, Robert Ivanek, PhD, Alexandar Tzankov, Antoine HFM Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 713.
https://doi.org/10.1182/blood.V130.Suppl_1.713.713
Published: 2017
Journal Articles

Conditional Expression of a Leukemogenic Fusion Oncogene in Murine Hematopoietic Stem Cells Results in Highly Invasive AML with Origin-Related Genetic Signatures of Prognostic Significance for the Human Disease

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Alexander Tzankov, MD PhD, Mathijs A. Sanders, MSc, Michael Kyba, PhD, Peter J.M. Valk, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2014) 124 (21): 779.
https://doi.org/10.1182/blood.V124.21.779.779
Published: 2014
Journal Articles

A Novel Conditional Mouse Model For MLL-ENL Induced Acute Leukemia

Vaia Stavropoulou, PhD, Sabine Juge, Alexander Tzankov, MD, PhD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2013) 122 (21): 1277.
https://doi.org/10.1182/blood.V122.21.1277.1277
Published: 2013
Journal Articles

Cellular and Molecular Targets of MLL-AF9 in a Novel Conditional Mouse Model

Vaia Stavropoulou, PhD, Susanne Kaspar, Laurent Brault, PhD, Sabine Juge, Stefano Morettini, PhD, Alexander Tzankov, MD, Michael Kyba, PhD, Antoine H.F.M. Peters, PhD, Juerg Schwaller, MD
Journal: Blood
Blood (2012) 120 (21): 1280.
https://doi.org/10.1182/blood.V120.21.1280.1280
Published: 2012