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Juliette Roels
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Journal Articles

Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia

Sunniyat Rahman, Gianna Bloye, Nadine Farah, Jonas Demeulemeester, Joana R. Costa, David O’Connor, Rachael Pocock, Tanya Rapoz-D’Silva, Adam Turna, Lingyi Wang, SooWah Lee, Adele K. Fielding, Juliette Roels, Roman Jaksik, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Jim R. Hughes, James O. J. Davies, Alejandro Gutierrez, Michelle A. Kelliher, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2024) 144 (22): 2319–2326.
https://doi.org/10.1182/blood.2024024300
Published: 2024
Includes: Supplemental data
Journal Articles

IRX3 Oncogene Activation in T-ALL through Enhancer Hijacking Caused By fto Intron 8 Deletions

Sunniyat Rahman, Nadine Farah, Jonas Demeulemeester, Joana R Costa, Gianna Bloye, David O'Connor, Rachael Pocock, Adam Turna, SooWah Lee, Adele K. Fielding, Juliette Roels, Małgorzata Dawidowska, Pieter Van Vlierberghe, Suzana Hadjur, Alejandro Gutierrez, Michelle A Kelliher, Simone Riva, Jim R. Hughes, James O.J. Davies, Peter Van Loo, Mark A. Dawson, Marc R. Mansour
Journal: Blood
Blood (2022) 140 (Supplement 1): 1009–1010.
https://doi.org/10.1182/blood-2022-162930
Published: 2022
Journal Articles

Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-Cell Acute Lymphoblastic Leukemia

Juliette Roels, Morgan Thénoz, Bronisława Szarzyńska, Mattias Landfors, Stien De Coninck, Lisa Demoen, Lien Provez, Anna Kuchmiy, Steven Strubbe, Lindy Reunes, Tim Pieters, PhD, Filip Matthijssens, PhD, Wouter Van Loocke, Tim Lammens, PhD, Barbara De Moerloose, MD PhD, Marc R. Mansour, MD PhD, Utpal Dave, MD, Steven Goossens, PhD, David J. Curtis, MBBS,PhD, Tom Taghon, PhD, Małgorzata Dawidowska, PhD, Sofie Degerman, PhD, Pieter Van Vlierberghe, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-138501
Published: 2020
Journal Articles

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Laura Kiekens, Eva Persyn, Els Van Ammel, Katrien De Mulder, Juliette Roels, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tessa C. C. Kerre, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq
Journal: Blood
Blood (2020) 136 (3): 288–298.
https://doi.org/10.1182/blood.2020005204
Published: 2020
Includes: Supplemental data
Journal Articles

Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma

Renate De Smedt, Julie Morscio, Lindy Reunes, Juliette Roels, Valentina Bardelli, Beatrice Lintermans, Wouter Van Loocke, Afonso Almeida, Laurence C. Cheung, Rishi S. Kotecha, Marc R. Mansour, Anne Uyttebroeck, Peter Vandenberghe, Roberta La Starza, Cristina Mecucci, Tim Lammens, Nadine Van Roy, Barbara De Moerloose, João T. Barata, Tom Taghon, Steven Goossens, Pieter Van Vlierberghe
Journal: Blood
Blood (2020) 135 (19): 1685–1695.
https://doi.org/10.1182/blood.2019003880
Published: 2020
Includes: Supplemental data
Journal Articles

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Renate De Smedt, MSc, Sofie Peirs, PhD, Julie Morscio, PhD, Juliette Roels, MSc, Steven Goossens, PhD, Aurore Touzart, MD, Anne Uyttebroeck, Nadine Van Roy, PhD, Tim Lammens, PhD, Lara Mussolin, PhD, Elizabeth Macyntire, MD PhD, Peter Vandenberghe, MD PhD, Pieter Van Vlierberghe, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1445.
https://doi.org/10.1182/blood.V130.Suppl_1.1445.1445
Published: 2017