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Journal Articles

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

Sylvie Taveirne, Sigrid Wahlen, Wouter Van Loocke, Laura Kiekens, Eva Persyn, Els Van Ammel, Katrien De Mulder, Juliette Roels, Laurentijn Tilleman, Marc Aumercier, Patrick Matthys, Filip Van Nieuwerburgh, Tessa C. C. Kerre, Tom Taghon, Pieter Van Vlierberghe, Bart Vandekerckhove, Georges Leclercq

Blood (2020) 136 (3): 288–298.

https://doi.org/10.1182/blood.2020005204

Published: 2020

Includes: Supplemental data

Journal Articles

The Checkpoint for Agonist Selection Precedes Conventional Selection in Human Thymus

Greet Verstichel, David Vermijlen, Liesbet Martens, Glenn Goetgeluk, Yvan Saeys, Cheroutre Hilde, Bart Vandekerckhove, MD PhD

Blood (2016) 128 (22): 860.

https://doi.org/10.1182/blood.V128.22.860.860

Published: 2016

Journal Articles

Functional Evaluation of T-Cells Generated from WT1-TCR Transduced Human Hematopoietic Stem Cells Using the OP9-DL1 Coculture System

Sarah Bonte, Master in Biomedical MDcine, Sylvia Snauwaert, MD PhD, Jasper Van Heuverswyn, Glenn Goetgeluk, Mirjam H.M. Heemskerk, PhD, Hans Stauss, MD PhD, Renata Stripecke, PhD, Bart Vandekerckhove, MD PhD, Tessa Kerre, MD PhD

Blood (2014) 124 (21): 2152.

https://doi.org/10.1182/blood.V124.21.2152.2152

Published: 2014

Journal Articles

Polyfunctional Tumor Antigen-specific T Cells Generated in Vitro from Human CD34 Positive Precursor Cells Transduced to Express T Cell Receptor αβ Chains Fused to CD28-CD3ζ Signaling Cassette

Yasmine Van Caeneghem, Glenn Goetgeluk, Sylvia Snauwaert, MD, Fritz Offner, MD, Reno Debets, Tessa Kerre, MD PhD, Bart Vandekerckhove, MD PhD

Blood (2014) 124 (21): 3830.

https://doi.org/10.1182/blood.V124.21.3830.3830

Published: 2014

Journal Articles

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

Sylvie Taveirne, Jessica Filtjens, Els Van Ammel, Veerle De Colvenaer, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Werner Held, Georges Leclercq

Blood (2011) 118 (2): 339–347.

https://doi.org/10.1182/blood-2011-01-331124

Published: 2011

Includes: Supplemental data

Journal Articles

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle, Greet De Smet, Martina Gärtner, Magda De Smedt, Els Waegemans, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Jon C. Aster, Irwin D. Bernstein, Cynthia J. Guidos, Bruno Kyewski, Tom Taghon

Blood (2011) 117 (17): 4449–4459.

https://doi.org/10.1182/blood-2010-06-290049

Published: 2011

Includes: Supplemental data

Journal Articles

CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures.

Stefanie Van Coppernolle, Bart Vandekerckhove, MD, PhD, Greet Verstichel, MD, Imke Velghe, Tom Taghon, PhD, Georges Leclercq, PhD, Jean Plum, MD, PhD, Tessa C. C. Kerre, MD, PhD

Blood (2009) 114 (22): 3670.

https://doi.org/10.1182/blood.V114.22.3670.3670

Published: 2009

Journal Articles

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

Tom Taghon, Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Bart Vandekerckhove, Jean Plum

Blood (2009) 113 (14): 3254–3263.

https://doi.org/10.1182/blood-2008-07-168906

Published: 2009

Includes: Supplemental data

Journal Articles

An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Inge Van de Walle, Greet De Smet, Magda De Smedt, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Tom Taghon

Blood (2009) 113 (13): 2988–2998.

https://doi.org/10.1182/blood-2008-06-164871

Published: 2009

Includes: Supplemental data

Journal Articles

Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator

Tina Van Den Broeck, Frederik Stevenaert, Sylvie Taveirne, Veronique Debacker, Christel Vangestel, Bart Vandekerckhove, Tom Taghon, Patrick Matthys, Jean Plum, Werner Held, Mieke Dewerchin, Wayne M. Yokoyama, Georges Leclercq

Blood (2008) 112 (13): 5046–5051.

https://doi.org/10.1182/blood-2008-06-164350

Published: 2008

Journal Articles

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcrαβ And Tcrγδ T Cells, through Both Conventional and Aberrant Developmental Pathways

Tessa C. C. Kerre, MD, PhD, Greet Verstichel, MD, Stefanie Van Coppernolle, Imke Velghe, Frank Timmermans, MD, Jean Plum, MD, PhD, Bart Vandekerckhove, MD, PhD

Blood (2008) 112 (11): 2902.

https://doi.org/10.1182/blood.V112.11.2902.2902

Published: 2008

Journal Articles

Generation of T Cells from Human Embryonic Stem Cells.

Frank Timmermans, MD, Imke Velghe, Lieve Van Walleghem, MD, Magda De Smedt, Stefanie Van Coppernolle, Georges Leclercq, PhD, Tom Taghon, PhD, Harry Moore, PhD, Anton W Langerak, PhD, Tessa C. C. Kerre, MD, PhD, Jean Plum, MD, PhD, Bart Vandekerckhove, MD, PhD

Blood (2008) 112 (11): 1527.

https://doi.org/10.1182/blood.V112.11.1527.1527

Published: 2008

Journal Articles

Endothelial Cells Are Not Derived from Hematopoietic Precursor Cells.

Frank Timmermans, MD, Magda De Smedt, Robrecht Raedt, Jean Plum, MD PhD, Bart Vandekerckhove, MD, PhD

Blood (2006) 108 (11): 1815.

https://doi.org/10.1182/blood.V108.11.1815.1815

Published: 2006

Journal Articles

Selection of Cord Blood Units Based on CD34+ Cells for Storage in Cord Blood Bank.

Bart Vandekerckhove, MD, PhD, Inge Van haute, MD, Nele Lootens, Carine De Buck, Linda Verdegem, Viviane Van De Steene, Saskia De Smet, David Craeye

Blood (2004) 104 (11): 4999.

https://doi.org/10.1182/blood.V104.11.4999.4999

Published: 2004

Journal Articles

Safety and Efficacy of Pathogen-Inactivated Platelets Transfused in Routine Use to Pediatric Patients: An Interim Report.

Yves Benoit, Inge Van Haute, Els Vandecruys, Barbara De Moerloose, Sophie Van Lancker, Kristien Mattheeus, Bart Vandekerckhove

Blood (2004) 104 (11): 3639.

https://doi.org/10.1182/blood.V104.11.3639.3639

Published: 2004

Journal Articles

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34 + cells

Tessa C. C. Kerre, Greet De Smet, Magda De Smedt, Alfred Zippelius, Mikaël J. Pittet, Anton W. Langerak, José De Bosscher, Fritz Offner, Bart Vandekerckhove, Jean Plum

Blood (2002) 99 (5): 1620–1626.

https://doi.org/10.1182/blood.V99.5.1620

Published: 2002

Journal Articles

Thymic Repopulation by CD34 + Human Cord Blood Cells After Expansion in Stroma-Free Culture

Bruno Verhasselt, Tessa Kerre, Evelien Naessens, Dominique Vanhecke, Magda De Smedt, Bart Vandekerckhove, Jean Plum

Blood (1999) 94 (11): 3644–3652.

https://doi.org/10.1182/blood.V94.11.3644

Published: 1999

NARROW

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

The Checkpoint for Agonist Selection Precedes Conventional Selection in Human Thymus

Functional Evaluation of T-Cells Generated from WT1-TCR Transduced Human Hematopoietic Stem Cells Using the OP9-DL1 Coculture System

Polyfunctional Tumor Antigen-specific T Cells Generated in Vitro from Human CD34 Positive Precursor Cells Transduced to Express T Cell Receptor αβ Chains Fused to CD28-CD3ζ Signaling Cassette

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures.

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcrαβ And Tcrγδ T Cells, through Both Conventional and Aberrant Developmental Pathways

Generation of T Cells from Human Embryonic Stem Cells.

Endothelial Cells Are Not Derived from Hematopoietic Precursor Cells.

Selection of Cord Blood Units Based on CD34+ Cells for Storage in Cord Blood Bank.

Safety and Efficacy of Pathogen-Inactivated Platelets Transfused in Routine Use to Pediatric Patients: An Interim Report.

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34 + cells

Thymic Repopulation by CD34 + Human Cord Blood Cells After Expansion in Stroma-Free Culture

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American Society of Hematology

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American Society of Hematology

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