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Journal Articles

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

Sylvie Taveirne, Jessica Filtjens, Els Van Ammel, Veerle De Colvenaer, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Werner Held, Georges Leclercq

Blood (2011) 118 (2): 339–347.

https://doi.org/10.1182/blood-2011-01-331124

Published: 2011

Includes: Supplemental data

Journal Articles

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle, Greet De Smet, Martina Gärtner, Magda De Smedt, Els Waegemans, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Jon C. Aster, Irwin D. Bernstein, Cynthia J. Guidos, Bruno Kyewski, Tom Taghon

Blood (2011) 117 (17): 4449–4459.

https://doi.org/10.1182/blood-2010-06-290049

Published: 2011

Includes: Supplemental data

Journal Articles

A Notch stairway to thymus?

Jean Plum

Blood (2010) 115 (2): 155–156.

https://doi.org/10.1182/blood-2009-11-250662

Published: 2010

Journal Articles

CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures.

Stefanie Van Coppernolle, Bart Vandekerckhove, MD, PhD, Greet Verstichel, MD, Imke Velghe, Tom Taghon, PhD, Georges Leclercq, PhD, Jean Plum, MD, PhD, Tessa C. C. Kerre, MD, PhD

Blood (2009) 114 (22): 3670.

https://doi.org/10.1182/blood.V114.22.3670.3670

Published: 2009

Journal Articles

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

Tom Taghon, Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Bart Vandekerckhove, Jean Plum

Blood (2009) 113 (14): 3254–3263.

https://doi.org/10.1182/blood-2008-07-168906

Published: 2009

Includes: Supplemental data

Journal Articles

An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Inge Van de Walle, Greet De Smet, Magda De Smedt, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Tom Taghon

Blood (2009) 113 (13): 2988–2998.

https://doi.org/10.1182/blood-2008-06-164871

Published: 2009

Includes: Supplemental data

Journal Articles

Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator

Tina Van Den Broeck, Frederik Stevenaert, Sylvie Taveirne, Veronique Debacker, Christel Vangestel, Bart Vandekerckhove, Tom Taghon, Patrick Matthys, Jean Plum, Werner Held, Mieke Dewerchin, Wayne M. Yokoyama, Georges Leclercq

Blood (2008) 112 (13): 5046–5051.

https://doi.org/10.1182/blood-2008-06-164350

Published: 2008

Journal Articles

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcrαβ And Tcrγδ T Cells, through Both Conventional and Aberrant Developmental Pathways

Tessa C. C. Kerre, MD, PhD, Greet Verstichel, MD, Stefanie Van Coppernolle, Imke Velghe, Frank Timmermans, MD, Jean Plum, MD, PhD, Bart Vandekerckhove, MD, PhD

Blood (2008) 112 (11): 2902.

https://doi.org/10.1182/blood.V112.11.2902.2902

Published: 2008

Journal Articles

Generation of T Cells from Human Embryonic Stem Cells.

Frank Timmermans, MD, Imke Velghe, Lieve Van Walleghem, MD, Magda De Smedt, Stefanie Van Coppernolle, Georges Leclercq, PhD, Tom Taghon, PhD, Harry Moore, PhD, Anton W Langerak, PhD, Tessa C. C. Kerre, MD, PhD, Jean Plum, MD, PhD, Bart Vandekerckhove, MD, PhD

Blood (2008) 112 (11): 1527.

https://doi.org/10.1182/blood.V112.11.1527.1527

Published: 2008

Journal Articles

MicroRNA signatures in Genetic Subtypes of T-Cell Acute Lymphoblastic Leukemia.

Blood (2008) 112 (11): 3360.

https://doi.org/10.1182/blood.V112.11.3360.3360

Published: 2008

Journal Articles

Notch signaling induces cytoplasmic CD3ϵ expression in human differentiating NK cells

Magda De Smedt, Tom Taghon, Inge Van de Walle, Greet De Smet, Georges Leclercq, Jean Plum

Blood (2007) 110 (7): 2696–2703.

https://doi.org/10.1182/blood-2007-03-082206

Published: 2007

Includes: Supplemental data

Journal Articles

Endothelial Cells Are Not Derived from Hematopoietic Precursor Cells.

Frank Timmermans, MD, Magda De Smedt, Robrecht Raedt, Jean Plum, MD PhD, Bart Vandekerckhove, MD, PhD

Blood (2006) 108 (11): 1815.

https://doi.org/10.1182/blood.V108.11.1815.1815

Published: 2006

Journal Articles

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells

Inge Hoebeke, Magda De Smedt, Inge Van de Walle, Katia Reynvoet, Greet De Smet, Jean Plum, Georges Leclercq

Blood (2006) 107 (7): 2879–2881.

https://doi.org/10.1182/blood-2005-05-1815

Published: 2006

Journal Articles

Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment

Magda De Smedt, Inge Hoebeke, Katia Reynvoet, Georges Leclercq, Jean Plum

Blood (2005) 106 (10): 3498–3506.

https://doi.org/10.1182/blood-2005-02-0496

Published: 2005

Includes: Supplemental data

Journal Articles

Ly49 and CD94/NKG2 receptor acquisition by NK cells does not require lymphotoxin-β receptor expression

Frederik Stevenaert, Katrien Van Beneden, Veerle De Colvenaer, Ann Sophie Franki, Veronique Debacker, Tom Boterberg, Dieter Deforce, Klaus Pfeffer, Jean Plum, Dirk Elewaut, Georges Leclercq

Blood (2005) 106 (3): 956–962.

https://doi.org/10.1182/blood-2004-10-4159

Published: 2005

Journal Articles

Negative thymocyte selection to HERV-K18 superantigens in humans

Françoise Meylan, Magda De Smedt, Georges Leclercq, Jean Plum, Olivier Leupin, Samuel Marguerat, Bernard Conrad

Blood (2005) 105 (11): 4377–4382.

https://doi.org/10.1182/blood-2004-07-2596

Published: 2005

Includes: Supplemental data

Journal Articles

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

Veronique Stove, Evelien Naessens, Christophe Stove, Tomek Swigut, Jean Plum, Bruno Verhasselt

Blood (2003) 102 (8): 2925–2932.

https://doi.org/10.1182/blood-2003-03-0833

Published: 2003

Includes: Supplemental data

Journal Articles

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34 + cells

Tessa C. C. Kerre, Greet De Smet, Magda De Smedt, Alfred Zippelius, Mikaël J. Pittet, Anton W. Langerak, José De Bosscher, Fritz Offner, Bart Vandekerckhove, Jean Plum

Blood (2002) 99 (5): 1620–1626.

https://doi.org/10.1182/blood.V99.5.1620

Published: 2002

Journal Articles

HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor

Tom Taghon, Frank Stolz, Magda De Smedt, Maggy Cnockaert, Bruno Verhasselt, Jean Plum, Georges Leclercq

Blood (2002) 99 (4): 1197–1204.

https://doi.org/10.1182/blood.V99.4.1197

Published: 2002

Journal Articles

Generation of T cells from adult human hematopoietic stem cells and progenitors in a fetal thymic organ culture system: stimulation by tumor necrosis factor-α

Steven F. A. Weekx, Hans W. Snoeck, Fritz Offner, Magda De Smedt, Dirk R. Van Bockstaele, Griet Nijs, Marc Lenjou, Adriaan Moulijn, Inez Rodrigus, Zwi N. Berneman, Jean Plum

Blood (2000) 95 (9): 2806–2812.

https://doi.org/10.1182/blood.V95.9.2806.009k01_2806_2812

Published: 2000

NARROW

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

A Notch stairway to thymus?

CD4 and CD8 TCRαβ Cells Are selected On MHC Expressed On Thymocyte Precursors in OP9-DL1 Cultures.

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator

OP9-DL1 Cell Line Supports the Development of Phenotypically and Functionally Mature Tcrαβ And Tcrγδ T Cells, through Both Conventional and Aberrant Developmental Pathways

Generation of T Cells from Human Embryonic Stem Cells.

MicroRNA signatures in Genetic Subtypes of T-Cell Acute Lymphoblastic Leukemia.

Notch signaling induces cytoplasmic CD3ϵ expression in human differentiating NK cells

Endothelial Cells Are Not Derived from Hematopoietic Precursor Cells.

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells

Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment

Ly49 and CD94/NKG2 receptor acquisition by NK cells does not require lymphotoxin-β receptor expression

Negative thymocyte selection to HERV-K18 superantigens in humans

Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34 + cells

HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor

Generation of T cells from adult human hematopoietic stem cells and progenitors in a fetal thymic organ culture system: stimulation by tumor necrosis factor-α

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American Society of Hematology

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American Society of Hematology

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