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Yves Benoit
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Journal Articles

Fertility Status Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Teresa De Rojas, MD, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2563.
https://doi.org/10.1182/blood.V130.Suppl_1.2563.2563
Published: 2017
Journal Articles

Socioeconomic Outcomes Among Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled between 1971 and 1998 in the EORTC Children Leukemia Group Trials 58741, 58831/2 and 58881

Melissa Barbati, Michal Kicinski, Stefan Suciu, Yves Benoit, Françoise Mazingue, Teresa De Rojas, MD, Els Vandecruys, Geneviève Plat, Anne Uyttebroeck, Patric Lutz, Marie-Françoise Dresse, Pauline Simon, Claire Pluchart, Odile Minckes, Alina Ferster, MD, Claire Freycon, Frédéric Millot, Jutte Van Der Werff, Christophe Chantrain, Robert Paulus, Pierre Rohrlich, Caroline Piette
Journal: Blood
Blood (2017) 130 (Supplement 1): 2191.
https://doi.org/10.1182/blood.V130.Suppl_1.2191.2191
Published: 2017
Journal Articles

Impact of Age and Treatment Group in Childhood High Hyperdiploid Low Risk B-Cell Acute Lymphoblastic Leukemia (ALL): Results of the CLG-EORTC 58951 Study

Laura Clement, Stefan Suciu, PhD, Isabelle Luquet, MD, Alina Ferster, MD PhD, Karima Yakouben, MD, Anne Uytterbroeck, Catherine Paillard, MD PhD, Nicolas Sirvent, Vitor Costa, Barbara De Moerloose, MD, Francoise Mazingue, Emmanuel Plouvier, MD, Martine Munzer, Maryline Poirée, Odile Minckes, MD, Frédéric Millot, MD, Dominique Plantaz, Caroline Piette, Frank Speleman, Prof, Hélène Cavé, Jutte VanderWerff-tenBossch, Pierre Simon Rohrlich, MDPhD, Yves Bertrand, Yves Benoit, Geneviève Plat
Journal: Blood
Blood (2016) 128 (22): 1743.
https://doi.org/10.1182/blood.V128.22.1743.1743
Published: 2016
Journal Articles

Unique Long Non-Coding RNA Expression Signature in ETV6/RUNX1-Driven B-Cell Precursor Acute Lymphoblastic Leukemia

Farzaneh Ghazavi, Barbara De Moerloose, MD, Wouter Van Loocke, Annelynn Wallaert, Alina Ferster, Marleen Bakkus, PhD, Genevieve Plat, MD, Eric Delabesse, PharmD, PhD, Anne Uyttebroeck, Filip Van Nieuwerburgh, PharmD, Prof, Dieter Deforce, PharmD, Prof, Nadine van Roy, MD Prof, Frank Speleman, Prof, Yves Benoit, Tim Lammens, Pieter van Vlierberghe, Prof
Journal: Blood
Blood (2016) 128 (22): 3920.
https://doi.org/10.1182/blood.V128.22.3920.3920
Published: 2016
Journal Articles

Prophylactic CNS Therapy (with or without Radiation Therapy) in Medium-High Risk Acute Lymphoblastic Leukemia (ALL) Children: Long-Term Outcome Evaluation of the Randomized BFM-Oriented Trial 58832 (period 1983-1989) of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Yves Bertrand, Anne Uyttebroeck, Els Vandecruys, Geneviève Plat, Patrick Lutz, Claire Pluchart, Nicolas Sirvent, Maryline Poirée, Pauline Simon, Alina Ferster, Claire Hoyoux, Francoise Mazingue, Robert Paulus, Dominique Plantaz, Caroline Thomas, Caroline Gilotay, Jutte Van Der Werff Ten Bosch, Pierre Simon Rohrlich, Yves Benoit
Journal: Blood
Blood (2016) 128 (22): 2775.
https://doi.org/10.1182/blood.V128.22.2775.2775
Published: 2016
Journal Articles

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia

Hetty H. Helsmoortel, Silvia Bresolin, Tim Lammens, Hélène Cavé, Peter Noellke, Aurélie Caye, Farzaneh Ghazavi, Andrica de Vries, Henrik Hasle, Veerle Labarque, Riccardo Masetti, Jan Stary, Marry M. van den Heuvel-Eibrink, Jan Philippé, Nadine Van Roy, Yves Benoit, Frank Speleman, Charlotte Niemeyer, Christian Flotho, Giuseppe Basso, Geertruy te Kronnie, Pieter Van Vlierberghe, Barbara De Moerloose
Journal: Blood
Blood (2016) 127 (9): 1163–1172.
https://doi.org/10.1182/blood-2015-09-667808
Published: 2016
Includes: Supplemental data
Journal Articles

t(12;21)/ ETV6 - RUNX1 Confers a Specific Pattern of In Vivo Sensitivity to Treatments in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Trials 58881 and 58951 of the EORTC Children Leukemia Group

Caroline Piette, Stefan Suciu, Emmanuelle Clappier, Yves Bertrand, MDPhD, Genevieve Plat, MD, Christophe Chantrain, Vitor Costa, Nicole Dastugue, Alina Ferster, Caroline Gilotay, Sandrine Girard, Nathalie Grardel, Patrick Lutz, Francoise Mazingue, MD, Odile Minckes, Martine Munzer, Emmanuel Plouvier, MD, Nicolas Sirvent, Anne Uyttebroeck, Nadine van Roy, MD, Karima Yakouben, MD, Yves Benoit, Hélène Cavé
Journal: Blood
Blood (2015) 126 (23): 793.
https://doi.org/10.1182/blood.V126.23.793.793
Published: 2015
Journal Articles

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

Joni Van der Meulen, Viraj Sanghvi, Konstantinos Mavrakis, Kaat Durinck, Fang Fang, Filip Matthijssens, Pieter Rondou, Monica Rosen, Tim Pieters, Peter Vandenberghe, Eric Delabesse, Tim Lammens, Barbara De Moerloose, Björn Menten, Nadine Van Roy, Bruno Verhasselt, Bruce Poppe, Yves Benoit, Tom Taghon, Ari M. Melnick, Frank Speleman, Hans-Guido Wendel, Pieter Van Vlierberghe
Journal: Blood
Blood (2015) 125 (1): 13–21.
https://doi.org/10.1182/blood-2014-05-577270
Published: 2015
Includes: Supplemental data
Journal Articles

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie Peirs, Filip Matthijssens, Steven Goossens, Inge Van de Walle, Katia Ruggero, Charles E. de Bock, Sandrine Degryse, Kirsten Canté-Barrett, Delphine Briot, Emmanuelle Clappier, Tim Lammens, Barbara De Moerloose, Yves Benoit, Bruce Poppe, Jules P. Meijerink, Jan Cools, Jean Soulier, Terence H. Rabbitts, Tom Taghon, Frank Speleman, Pieter Van Vlierberghe
Journal: Blood
Blood (2014) 124 (25): 3738–3747.
https://doi.org/10.1182/blood-2014-05-574566
Published: 2014
Includes: Supplemental data
Journal Articles

Prognostic Relevance of CD200 /Btla Deletions in Pediatric Precursor-B Cell Acute Lymphoblastic Leukemia Treated According to the EORTC-CLG 58951 Protocol

Farzaneh Ghazavi, Tim Lammens, Emmanuelle Clappier, Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Yves Bertrand, Odile Minckes, Vitor Costa, Alina Ferster, Françoise Mazingue, Geneviève Plat, Emmanuel Plouvier, Marilyne Poirée, Anne Uyttebroeck, Jutte Van der Werff Ten Bosch, Hetty Helsmoortel, Magali Meul, Nadine Van Roy, Jan Philippé, Frank Speleman, Hélène Cavé, Pieter Van Vlierberghe, Barbara De Moerloose
Journal: Blood
Blood (2014) 124 (21): 2394.
https://doi.org/10.1182/blood.V124.21.2394.2394
Published: 2014
Journal Articles

The NOTCH1 Driven Long Non-Coding RNA Repertoire in T-Cell Acute Lymphoblastic Leukemia

Annelynn Wallaert, Kaat Durinck, Pieter Rondou, PhD, Inge van de Walle, Wouter Vanloocke, Pieter-Jan Volders, Suzanne Vanhauwaert, Ellen Geerdens, Maté Ongenaert, Nadine Van Roy, Bruce Graham Poppe, MD PhD, Yves Benoit, Jan Cools, PhD, Jo Vandesompele, PhD, Jean Soulier, MD PhD, Pieter Van Vlierberghe, Tom Taghon, PhD, Frank Speleman
Journal: Blood
Blood (2014) 124 (21): 900.
https://doi.org/10.1182/blood.V124.21.900.900
Published: 2014
Journal Articles

Expanding The TLX1-Regulome In T Cell Acute Lymphoblastic Leukemia Towards Long Non-Coding RNAs

Kaat Durinck, Joni Van der Meulen, Maté Ongenaert, Pieter-Jan Volders, Annelynn Wallaert, Nadine Van Roy, PhD, Yves Benoit, Bruce Poppe, MD, Pieter Mestdagh, PhD, Jo Vandesompele, PhD, Pieter Rondou, PhD, Jean Soulier, MD, PhD, Pieter Van Vlierberghe, Frank Speleman, PhD
Journal: Blood
Blood (2013) 122 (21): 813.
https://doi.org/10.1182/blood.V122.21.813.813
Published: 2013
Journal Articles

Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results

Clinical Trials & Observations
Nicole Dastugue, Stefan Suciu, Geneviève Plat, Frank Speleman, Hélène Cavé, Sandrine Girard, Marleen Bakkus, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, Anne Uyttebroeck, Carine Gervais, Patrick Lutz, Manuel R. Teixeira, Pierre Heimann, Alice Ferster, Pierre Rohrlich, Marie Agnès Collonge, Martine Munzer, Isabelle Luquet, Patrick Boutard, Nicolas Sirvent, Matthias Karrasch, Yves Bertrand, Yves Benoit
Journal: Blood
Blood (2013) 121 (13): 2415–2423.
https://doi.org/10.1182/blood-2012-06-437681
Published: 2013
Includes: Supplemental data
Journal Articles

ERG Intragenic Deletion Characterizes a Distinct Oncogenic Subtype of B-Cell Precursor Acute Lymphoblastic Leukemia with a Favourable Outcome Despite Frequent IKZF1 Deletions

Emmanuelle Clappier, André Baruchel, Jérôme Rapion, Aurélie Caye, Ahlème Khemiri, Lucie Hernandez, Emmanuelle Kabongo, Thierry Leblanc, Karima Yakouben, Geneviève Plat, Vitor Costa, Alina Ferster, Séraphine Rossi, Sandrine Girard, Nicole Dastugue, Marleen Bakkus, Stefan Suciu, Yves Benoit, Yves Bertrand, Jean Soulier, Hélène Cavé
Journal: Blood
Blood (2012) 120 (21): 121.
https://doi.org/10.1182/blood.V120.21.121.121
Published: 2012
Journal Articles

Low CNS Relapse Incidence without Radiotherapy and Improvement of Outcome: Results of Subsequent EORTC-CLG 58881 and 58951 Trials in Pediatric T-Cell Acute Lymphoblastic Leukemia (ALL)

Barbara De Moerloose, Stefan Suciu, Alina Ferster, Françoise Mazingue, Nicolas Sirvent, Vitor Costa, Karima Yakouben, Patrick Lutz, Anne Uyttebroeck, Dominique Plantaz, Geneviève Plat, Frédéric Millot, Pierre Rohrlich, Maryline Poiree, Jutte Van der Werff Ten Bosch, Claire Hoyoux, Patrick Boutard, Hélène Cavé, PhD, Sandrine Girard, Francisco Bautista Sirvent, Yves Benoit, Yves Bertrand
Journal: Blood
Blood (2012) 120 (21): 133.
https://doi.org/10.1182/blood.V120.21.133.133
Published: 2012
Journal Articles

Prolonged E. Coli Asparaginase Therapy Does Not Improve Significantly the Outcome for Children with Low and Average Risk Acute Lymphoblastic Leukemia (ALL) and Non Hodgkin Lymphoma (NHL): Final Report of the EORTC-CLG Randomized Phase III Trial 58951

Veerle Mondelaers, Stefan Suciu, Barbara De Moerloose, Alina Ferster, MD, Françoise Mazingue, Geneviève Plat, Karima Yakouben, Anne Uyttebroeck, Patrick Lutz, Vitor Costa, Nicolas Sirvent, Pierre Rohrlich, Martine Munzer, Maryline Poiree, Patrick Boutard, Frédéric Millot, Dominique Plantaz, Philip Maes, Claire Hoyoux, Hélène Cavé, PhD, Yves Bertrand, Yves Benoit
Journal: Blood
Blood (2012) 120 (21): 134.
https://doi.org/10.1182/blood.V120.21.134.134
Published: 2012
Journal Articles

In Childhood B-Lineage Acute Lymphoblastic Leukemia (B-ALL) with Hyperdiploidy >50 Chromosomes, Patients with 58 to 66 Chromosomes Have 99% EFS At 6-Year Follow-up: Results of the EORTC CLG 58951 Trial

Nicole Dastugue, Stefan Suciu, Geneviève Plat, Frank Speleman, PhD, Hélène Cavé, Sandrine Girard, Emmanuelle Delabesse, Marie Pierre Pagès, Karima Yakouben, Brigitte Nelken, Francoise Mazingue, MD, Anne Hagemeijer, Anne Uyttebroeck, Carine Gervais, MD, Patrick Lutz, Manuel Teixera, Lucilia Norton, Pierre Heimann, Alina Ferster, Ghislaine Plessis, Patrick Boutard, Marie Agnès Collonge, Pierre Rohrlich, MD, PhD, Isabelle Luquet, MD, PhD, Martine Munzer, Nicolas Sirvent, Dominique Plantaz, Christian Herens, Claire Hoyoux, Matthias Karrasch, Yves Bertrand, Yves Benoit, MD
Journal: Blood
Blood (2011) 118 (21): 565.
https://doi.org/10.1182/blood.V118.21.565.565
Published: 2011
Journal Articles

The Prognosis of Children Acute Lymphoblastic Leukemia (ALL) with Minimal Residual Disease (MRD) ≥10-2 After Induction (TP1) Depends on the Prephase Response and on the Level of the MRD After Consolidation (TP2): Results of the 58951EORTC Trial

Yves Bertrand, Stefan Suciu, Nathalie Grardel, Marleen Bakkus, PhD, Francoise Mazingue, MD, Karima Yacouben, Anne Uyttebroeck, Patrick Lutz, Dominique Plantaz, Sandrine Girard, Nicole Dastugue, Yves Benoit, MD, Hélène Cavé
Journal: Blood
Blood (2011) 118 (21): 2571.
https://doi.org/10.1182/blood.V118.21.2571.2571
Published: 2011
Journal Articles

Similar Efficacy and Toxicity Profile for Idarubicine and Mitoxantrone in Induction and Intensification Treatment of Children with Acute Myeloid Leukemia (AML) or Myelodysplasia (MDS): Long-Term Results of the EORTC-CLG Randomized Phase III Trial 58921

Barbara De Moerloose, Stefan Suciu, Martine Munzer, Caroline Piette, Karima Yakouben, Genevieve Margueritte, Patrick Lutz, Anne Uyttebroeck, Pierre Rohrlich, MD, PhD, Alina Ferster, Patrick Boutard, Marie-Françoise Dresse, Xavier Rialland, Lucilia Norton, Nicolas Sirvent, Matthias Karrasch, Yves Benoit, MD, Yves Bertrand
Journal: Blood
Blood (2011) 118 (21): 2615.
https://doi.org/10.1182/blood.V118.21.2615.2615
Published: 2011
Journal Articles

Regulatory Networks Governed by MicroRNAs in T-ALL Oncogenesis and Normal T-Cell Development

Joni Van der Meulen, Evelien Mets, Pieter Mestdagh, PhD, Peter Pipelers, Tom Taghon, PhD, David Camacho Trujillo, PhD, David Avran, Gert Van Peer, Nadine Van Roy, PhD, Olivier Thas, PhD, Yves Benoit, MD, Jo Vandesompele, PhD, Bruce Poppe, MD, Pieter Van Vlierberghe, PhD, Pieter Rondou, PhD, Jean Soulier, MD, Frank Speleman, PhD
Journal: Blood
Blood (2011) 118 (21): 1366.
https://doi.org/10.1182/blood.V118.21.1366.1366
Published: 2011