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ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie Peirs, Filip Matthijssens, Steven Goossens, Inge Van de Walle, Katia Ruggero, Charles E. de Bock, Sandrine Degryse, Kirsten Canté-Barrett, Delphine Briot, Emmanuelle Clappier, Tim Lammens, Barbara De Moerloose, Yves Benoit, Bruce Poppe, Jules P. Meijerink, Jan Cools, Jean Soulier, Terence H. Rabbitts, Tom Taghon, Frank Speleman, Pieter Van Vlierberghe
Journal: Blood
Blood (2014) 124 (25): 3738–3747.
https://doi.org/10.1182/blood-2014-05-574566
Published: 2014
Includes: Supplemental data
Journal Articles

The NOTCH1 Driven Long Non-Coding RNA Repertoire in T-Cell Acute Lymphoblastic Leukemia

Annelynn Wallaert, Kaat Durinck, Pieter Rondou, PhD, Inge van de Walle, Wouter Vanloocke, Pieter-Jan Volders, Suzanne Vanhauwaert, Ellen Geerdens, Maté Ongenaert, Nadine Van Roy, Bruce Graham Poppe, MD PhD, Yves Benoit, Jan Cools, PhD, Jo Vandesompele, PhD, Jean Soulier, MD PhD, Pieter Van Vlierberghe, Tom Taghon, PhD, Frank Speleman
Journal: Blood
Blood (2014) 124 (21): 900.
https://doi.org/10.1182/blood.V124.21.900.900
Published: 2014
Journal Articles

Transcriptional Antagonism Between the Cooperative Oncogenes TLX1 and NOTCH1 in T-Cell Acute Lymphoblastic Leukemia

Kaat Durinck, Wouter Vanloocke, Joni Van der Meulen, Inge van de Walle, Pieter Rondou, PhD, Charles De Bock, Bruno Verhasselt, Bruce Graham Poppe, MD PhD, Jan Cools, PhD, Jean Soulier, MD PhD, Tom Taghon, PhD, Frank Speleman, Pieter Van Vlierberghe
Journal: Blood
Blood (2014) 124 (21): 3588.
https://doi.org/10.1182/blood.V124.21.3588.3588
Published: 2014
Journal Articles

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

Inge Van de Walle, Greet De Smet, Martina Gärtner, Magda De Smedt, Els Waegemans, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Jon C. Aster, Irwin D. Bernstein, Cynthia J. Guidos, Bruno Kyewski, Tom Taghon
Journal: Blood
Blood (2011) 117 (17): 4449–4459.
https://doi.org/10.1182/blood-2010-06-290049
Published: 2011
Includes: Supplemental data
Journal Articles

Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development

Tom Taghon, Inge Van de Walle, Greet De Smet, Magda De Smedt, Georges Leclercq, Bart Vandekerckhove, Jean Plum
Journal: Blood
Blood (2009) 113 (14): 3254–3263.
https://doi.org/10.1182/blood-2008-07-168906
Published: 2009
Includes: Supplemental data
Journal Articles

An early decrease in Notch activation is required for human TCR-αβ lineage differentiation at the expense of TCR-γδ T cells

Inge Van de Walle, Greet De Smet, Magda De Smedt, Bart Vandekerckhove, Georges Leclercq, Jean Plum, Tom Taghon
Journal: Blood
Blood (2009) 113 (13): 2988–2998.
https://doi.org/10.1182/blood-2008-06-164871
Published: 2009
Includes: Supplemental data
Journal Articles

Notch signaling induces cytoplasmic CD3ϵ expression in human differentiating NK cells

Magda De Smedt, Tom Taghon, Inge Van de Walle, Greet De Smet, Georges Leclercq, Jean Plum
Journal: Blood
Blood (2007) 110 (7): 2696–2703.
https://doi.org/10.1182/blood-2007-03-082206
Published: 2007
Includes: Supplemental data
Journal Articles

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells

Brief Report
Inge Hoebeke, Magda De Smedt, Inge Van de Walle, Katia Reynvoet, Greet De Smet, Jean Plum, Georges Leclercq
Journal: Blood
Blood (2006) 107 (7): 2879–2881.
https://doi.org/10.1182/blood-2005-05-1815
Published: 2006