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Journal Articles

PRC2 Inactivation Induces Resistance to Chemotherapy-Induced Apoptosis By Upregulating the TRAP1 Mitochondrial Chaperone in T-ALL

Kimberly Bodaar, MD, Ingrid M. Aries, PhD MSc, Salmaan Karim, Triona Ni Chonghaile, PhD BSc, Melissa A. Burns, MD, Laura Hinze, Maren Pfirrmann, James Degar, Jack Landrigan, Sebastian Balbach, Sofie Peirs, PhD, Bjorn Menten, PhD, Kristen E. Stevenson, MS, Donna S Neuberg, ScD, Meenakshi Devidas, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, David T Teachey, MD, Karen R. Rabin, MD PhD, Stuart S. Winter, MD, Kimberly P. Dunsmore, MD, Brent Wood, MD PhD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Pieter Van Vlierberghe, PhD, Stuart H. Orkin, MD, Birgit Knoechel, MDPhD, Anthony Letai, MD PhD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 889.
https://doi.org/10.1182/blood-2018-99-113518
Published: 2018
Journal Articles

The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia

Gayle P. Pouliot, MD PhD, Melissa A. Burns, MD, James Degar, Chau Vo, Lisa Moreau, Justine E. Roderick, PhD, Bose Kochupurakkal, PhD, Sofie Peirs, PhD, Bjorn Menten, PhD, Mignon L. Loh, MD, Stephen P. Hunger, MD, Lewis B. Silverman, MD, Stephen E. Sallan, MD, Marian H. Harris, MD PhD, Kristen E. Stevenson, MS, Donna S. Neuberg, ScD, David M. Weinstock, MD, Andrew P. Weng, MD PhD, Michelle Kelliher, PhD, Pieter Van Vlierberghe, PhD, Alan D. D'Andrea, MD, Alejandro Gutierrez, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2722.
https://doi.org/10.1182/blood.V130.Suppl_1.2722.2722
Published: 2017
Journal Articles

Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma

Renate De Smedt, MSc, Sofie Peirs, PhD, Julie Morscio, PhD, Juliette Roels, MSc, Steven Goossens, PhD, Aurore Touzart, MD, Anne Uyttebroeck, Nadine Van Roy, PhD, Tim Lammens, PhD, Lara Mussolin, PhD, Elizabeth Macyntire, MD PhD, Peter Vandenberghe, MD PhD, Pieter Van Vlierberghe, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1445.
https://doi.org/10.1182/blood.V130.Suppl_1.1445.1445
Published: 2017
Journal Articles

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Steven Goossens, Sofie Peirs, Wouter Van Loocke, Jueqiong Wang, Mina Takawy, Filip Matthijssens, Stefan E. Sonderegger, Katharina Haigh, Thao Nguyen, Niels Vandamme, Magdaline Costa, Catherine Carmichael, Filip Van Nieuwerburgh, Dieter Deforce, Oded Kleifeld, David J. Curtis, Geert Berx, Pieter Van Vlierberghe, Jody J. Haigh
Journal: Blood
Blood (2017) 129 (8): 981–990.
https://doi.org/10.1182/blood-2016-06-721191
Published: 2017
Includes: Supplemental data
Journal Articles

Oncogenic ZEB2 Activation Drives Sensitivity Towards LSD1 Inhibition in T-Cell Acute Lymphoblastic Leukemia

Steven Goossens, PhD, Sofie Peirs, MSc, Geert Berx, PhD, Pieter Van Vlierberghe, PhD, Jody J. Haigh, PhD
Journal: Blood
Blood (2016) 128 (22): 4027.
https://doi.org/10.1182/blood.V128.22.4027.4027
Published: 2016
Journal Articles

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Sofie Peirs, Filip Matthijssens, Steven Goossens, Inge Van de Walle, Katia Ruggero, Charles E. de Bock, Sandrine Degryse, Kirsten Canté-Barrett, Delphine Briot, Emmanuelle Clappier, Tim Lammens, Barbara De Moerloose, Yves Benoit, Bruce Poppe, Jules P. Meijerink, Jan Cools, Jean Soulier, Terence H. Rabbitts, Tom Taghon, Frank Speleman, Pieter Van Vlierberghe
Journal: Blood
Blood (2014) 124 (25): 3738–3747.
https://doi.org/10.1182/blood-2014-05-574566
Published: 2014
Includes: Supplemental data