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Journal Articles

Fractionated vs single-dose gemtuzumab ozogamicin with determinants of benefit in older patients with AML: the UK NCRI AML18 trial

CME Clinical Trials & Observations
Sylvie D. Freeman, Abin Thomas, Ian Thomas, Robert K. Hills, Paresh Vyas, Amanda Gilkes, Marlen Metzner, Niels Asger Jakobsen, Alison Kennedy, Rachel Moore, Nuria Marquez Almuina, Sarah Burns, Sophie King, Georgia Andrew, Kathleen M. E. Gallagher, Rob S. Sellar, Paul Cahalin, Duruta Weber, Mike Dennis, Priyanka Mehta, Steven Knapper, Nigel H. Russell
Journal: Blood
Blood (2023) 142 (20): 1697–1707.
https://doi.org/10.1182/blood.2023020630
Published: 2023
Includes: Supplemental data
Journal Articles

MRD Directed Treatment Intensification with Either FLAG-Ida or DA-Cladribine Improves Survival in Older AML Patients: Results from the NCRI AML18 Randomised Trial

Nigel H. Russell, Abin Thomas, Robert Hills, Ian Thomas, Amanda Gilkes, Nuria Almuina, Sarah Burns, Lucy Marsh, Georgia Andrew, Nicholas McCarthy, Jennifer Byrne, Rob Sellar, Richard J. Kelly, Paul Cahalin, Ulrik Malthe Overgaard, Priyanka Mehta, Mike Dennis, Steve Knapper, Sylvie D Freeman
Journal: Blood
Blood (2023) 142 (Supplement 1): 830.
https://doi.org/10.1182/blood-2023-185956
Published: 2023
Journal Articles

High Molecular Response Rate and Overall Survival with FLT3 Inhibitors As MRD-Guided Salvage Treatment for Molecular Failure in AML

Jad Othman, Nicola Potter, Katya Mokretar, David Taussig, Anjum Khan, Pramila Krishnamurthy, Anne-Louise Latif, Paul Cahalin, James Aries, Mariam Amer, Edward Belsham, Eibhlin Conneally, Charles Craddock, Dominic Culligan, Mike Dennis, Caroline Duncan, Caroline Furness, Paraskevi Gkreka, Katherine Hodgson, Wendy Ingram, Andrew King, Panagiotis Kottaridis, Mary Frances McMullin, Unmesh Mohite, Loretta Ngu, Katharine Patrick, Tom Rider, Wing Roberts, Marianne Tang Severinsen, Neill Storrar, Tom Taylor, Nigel H. Russell, Richard Dillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 2002–2004.
https://doi.org/10.1182/blood-2022-159503
Published: 2022
Journal Articles

A Randomized Comparison of the Fractionated Versus Single Dose Schedule of Gemtuzumab Ozogamicin at Induction with Determinants of Benefit for Older AML Patients: UK NCRI AML18 Trial Results

Sylvie D Freeman, Abin Thomas, Ian Thomas, Paresh Vyas, Amanda Gilkes, Marlen Metzner, Niels Asger Jakobsen, Alison Kennedy, Amy Moore, Nuria Marquez Almuina, Sarah Burns, Sophie King, Georgia M. Andrew, Kathleen M.E. Gallagher, Rob Sellar, Paul Cahalin, Duruta Weber, Mike Dennis, Priyanka Mehta, Steve Knapper, Nigel H. Russell
Journal: Blood
Blood (2022) 140 (Supplement 1): 532–533.
https://doi.org/10.1182/blood-2022-162245
Published: 2022
Journal Articles

Interim Analysis of a Prospective Multicentre Study Using Next Generation Sequencing for Kinase Domain Mutational Analysis in CML Patients on First or Subsequent TKI Therapy

Hugues De Lavallade, Sophie Jackson, BSc, Heather Oakervee, BSc, MBBS, MD MRCP, FRCPath, Sebastian Francis, MBChB, MRCP, Edward Belsham, FRCPath, MB, Paul Cahalin, MA MRCP FRCPath, Joanne Ewing, PhDBMBS BSc FRPATH, Jenny Byrne, MD PhD, Kate Rothwell, BA MB BChir, PhD, Sandra Hassan, MBBS, MRCP, FRCPath, MDRes), Srinivas Pillai, MBBS,MD MRCP, FRCPath, Priyanka Mehta, Anshu Garg, MBBS,MDMRCP,FRCPath, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Oliver Ottmann, Prof, MD, Deepti Radia, Patrick Harrington, MRCP, FRCPath, Rachel Greig, Nicholas Lea, PhD, Michael Thompson, Aytug Kizilors, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2935.
https://doi.org/10.1182/blood-2019-129825
Published: 2019
Journal Articles

A Comparison of 1 or 2 Courses of High Dose Cytarabine As Consolidation in Younger Patients with AML: First Results of the UK NCRI AML17 Trial

Nigel H. Russell, MD, Robert K Hills, DPhil, Sylvie Freeman, PhDFRCPath, Steven Knapper, Lars Kjeldsen, MD PhD, Ian Thomas, Jamie Cavenagh, Paul Cahalin, Mary Frances McMullin, MD FRCPath, FRCP, Alan K. Burnett, MD FRCP
Journal: Blood
Blood (2015) 126 (23): 221.
https://doi.org/10.1182/blood.V126.23.221.221
Published: 2015
Journal Articles

A randomized comparison of daunorubicin 90 mg/m 2 vs 60 mg/m 2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients

CME Clinical Trials & Observations
Alan K. Burnett, Nigel H. Russell, Robert K. Hills, Jonathan Kell, Jamie Cavenagh, Lars Kjeldsen, Mary-Frances McMullin, Paul Cahalin, Mike Dennis, Lone Friis, Ian F. Thomas, Don Milligan, Richard E. Clark
Journal: Blood
Blood (2015) 125 (25): 3878–3885.
https://doi.org/10.1182/blood-2015-01-623447
Published: 2015
Includes: Supplemental data
Journal Articles

A Randomised Comparison of Daunorubicin 90mg/m 2 Vs 60mg/m 2 in AML Induction: Results from the UK NCRI AML17 Trial in 1206 Patients

Alan K. Burnett, MD, Nigel Russell, Robert K. Hills, MA MSc DPhil, Jonathan Kell, MD MB, Jamie Cavenagh, Lars Kjeldsen, MD PhD, Mary Frances McMullin, MDFRCPath, FRCP, Paul Cahalin, Mike Dennis, Donald Milligan, MD, Richard E Clark, MBBS MD
Journal: Blood
Blood (2014) 124 (21): 7.
https://doi.org/10.1182/blood.V124.21.7.7
Published: 2014
Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Lynn Quek, Georg Otto, Catherine Garnett, Ludovic Lhermitte, I-Jun Lau, Dimitris Karamitros, Jessica Doondeea, Batchimeg Usukhbayar, Nicolas Goardon, Adam Ivey, Yisu Gu, Christopher G Allen, Rosemary E Gale, Benjamin Davies, Alexander Sternberg, Sally Killick, Hannah Hunter, Paul Cahalin, Andrew Price, Andrew Carr, Mike Griffiths, Paul Virgo, Stephen Mackinnon, David Grimwade, Sylvie D Freeman, Nigel Russell, Charles Craddock, MDPhD, Adam Mead, MDPhD, Andrew Peniket, MD, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2014) 124 (21): 15.
https://doi.org/10.1182/blood.V124.21.15.15
Published: 2014
Journal Articles

A Comparison of Daunorubicin/Ara-C (DA) Versus Daunorubicin/Clofarabine (DClo) and Two Versus Three Courses of Total Treatment for Older Patients with AML and High Risk MDS: Results of the UK NCRI AML16 Trial

Alan K. Burnett, MD, Nigel H Russell, MD, Jonathan Kell, MD, MB, Lars Kjeldsen, MD, PhD, Donald Milligan, MD, FRCP, FRCPath, Paul Cahalin, Robert K. Hills, MA, MSc, DPhil
Journal: Blood
Blood (2012) 120 (21): 892.
https://doi.org/10.1182/blood.V120.21.892.892
Published: 2012
Journal Articles

Study on the Role of Recombinant Factor VIIa in the Management of Intractable Blood Loss in Patients without Inherited Bleeding Disorder in a UK District General Hospital.

Satarupa Choudhuri, Paul Kelsey, Paul Cahalin, Mac Macheta
Journal: Blood
Blood (2007) 110 (11): 3145.
https://doi.org/10.1182/blood.V110.11.3145.3145
Published: 2007