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Nicolas Goardon
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Journal Articles

A Novel Model of Human Hemopoiesis Based on Single Cell Functional and Transcriptional Analysis of Lympho-Myeloid Progenitors

Bilyana Stoilova, PhD, Dimitris Karamitros, PhD, Zahra Aboukhalil, Fiona Hamey, Andreas Reinisch, MD PhD, Marina Samitsch, PhD, Lynn Quek, FRCPath, DPhil, MBBS, Georg Otto, PhD, Emmanouela Repapi, PhD, Jessica Doondeea, Batchimeg Usukhbayar, Julien Calvo, PhD, Stephen Taylor, PhD, Nicolas Goardon, PhD, Emmanuelle Six, Francoise Pflumio, PhD, Catherine Porcher, PhD, Ravi Majeti, MD PhD, Berthold Gottgens, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, MRCP, MRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 2413.
https://doi.org/10.1182/blood.V130.Suppl_1.2413.2413
Published: 2017
Journal Articles

Functional and Genetic Heterogeneity of Distinct Leukemic Stem Cell Populations in CD34- Human Acute Myeloid Leukemia

Lynn Quek, Georg Otto, Catherine Garnett, Ludovic Lhermitte, I-Jun Lau, Dimitris Karamitros, Jessica Doondeea, Batchimeg Usukhbayar, Nicolas Goardon, Adam Ivey, Yisu Gu, Christopher G Allen, Rosemary E Gale, Benjamin Davies, Alexander Sternberg, Sally Killick, Hannah Hunter, Paul Cahalin, Andrew Price, Andrew Carr, Mike Griffiths, Paul Virgo, Stephen Mackinnon, David Grimwade, Sylvie D Freeman, Nigel Russell, Charles Craddock, MDPhD, Adam Mead, MDPhD, Andrew Peniket, MD, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2014) 124 (21): 15.
https://doi.org/10.1182/blood.V124.21.15.15
Published: 2014
Journal Articles

Leukemia Stem Cell Potential of Different Progenitor Subpopulations in Myeloid Blast Phase CML

Ross Kinstrie, PhD BSc, Dimitris Karamitros, Nicolas Goardon, Heather Morrison, BSc, Richard E Clark, MBBS MD, Paresh Vyas, Mhairi Copland, PhD BSc, MRCP, FRCPath
Journal: Blood
Blood (2014) 124 (21): 3489.
https://doi.org/10.1182/blood.V124.21.3489.3489
Published: 2014
Journal Articles

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Charles F. Craddock, MD PhD, Nicolas Goardon, PhD, Lynn Quek, MD, Sylvie Freeman, MD, PhD, Shamyla Siddique, Manoj Raghavan, Anna Schuh, PhD, David Grimwade, PhD, Robert K Hills, MA, MSc, DPhil, Cassandra Brookes, PhD, Michael Griffiths, PhD, James D. Cavenagh, MD, Ravindra Majeti, MD, PhD, Irving L. Weissman, MD, Alan K Burnett, MD, Paresh Vyas
Journal: Blood
Blood (2011) 118 (21): 638.
https://doi.org/10.1182/blood.V118.21.638.638
Published: 2011
Journal Articles

SCL-mediated regulation of the cell-cycle regulator p21 is critical for murine megakaryopoiesis

Hedia Chagraoui, Mira Kassouf, Sreemoti Banerjee, Nicolas Goardon, Kevin Clark, Ann Atzberger, Andrew C. Pearce, Radek C. Skoda, David J. P. Ferguson, Steve P. Watson, Paresh Vyas, Catherine Porcher
Journal: Blood
Blood (2011) 118 (3): 723–735.
https://doi.org/10.1182/blood-2011-01-328765
Published: 2011
Includes: Supplemental data
Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Nicolas Goardon, Emmanuele Marchi, Lynn Quek, Anna Schuh, Petter Woll, Adam Mead, Kate Alford, Amanda Gilkes, Kheira Beldjord, David Bowen, Graham Standen, Sally Killick, Hannah Hunter, Steven Knapper, Lisa Robinson, Alex Sternberg, James D Cavenagh, Paul Virgo, Mike Griffiths, Elizabeth A. Macintyre, PhD, FRCP, FRCPath, Charles Craddock, Alan Burnett, Tariq Enver, PhD, Sten Eirik W Jacobsen, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2010) 116 (21): 91.
https://doi.org/10.1182/blood.V116.21.91.91
Published: 2010
Journal Articles

A Transgenic Mouse Model for Congenital Dyserythropoietic Anemia Type I

Raffaele Renella, MD, Nigel A Roberts, BSc, Jacqueline A Sharpe, PhD, Pik-Shan Li, BSc, Jill M Brown, BSc, Christian Babbs, PhD, Cristina Fugazza, PhD, Nicolas Goardon, PhD, Douglas R Higgs, DSc, William G Wood, PhD
Journal: Blood
Blood (2008) 112 (11): 3455.
https://doi.org/10.1182/blood.V112.11.3455.3455
Published: 2008
Journal Articles

Reduced CD38 Expression on CD34+ Cells as a Diagnostic Test in Myelodysplastic Syndromes

Paresh Vyas, DPhil, FRCP, FRCPath, Nicolas Goardon, PhD, Alexander Sternberg, MRCP, FRCPath, Wai-Kit Chu, Charles F. Craddock, BM, MRCP, MRCPath, Richard Benson, FRCS, Sylvie Freeman, BM, MRCP, FRCPath
Journal: Blood
Blood (2008) 112 (11): 2670.
https://doi.org/10.1182/blood.V112.11.2670.2670
Published: 2008
Journal Articles

5′ Azacitidine in Combination with Valproic Acid Induces Complete Remissions in Patients with Advanced Acute Myeloid Leukaemia but Does Not Eradicate Clonal Leukaemic Stem/Progenitor Cells.

Charles Craddock, BM, DPhil, FRCP, FRCPath, Nicolas Goardon, Mike Griffiths, James D. Cavenagh, MD, Shamyla Siddique, Paresh Vyas, BM, DPhil, FRCP, FRCPath
Journal: Blood
Blood (2008) 112 (11): 945.
https://doi.org/10.1182/blood.V112.11.945.945
Published: 2008
Journal Articles

NKX3.1 Is a Direct TAL1 Target Gene That Mediates the TAL1 Dependent Proliferation of Human T-Cell Acute Lymphoblastic Leukemia (T-ALL)

Sophie Kusy, Nicolas Goardon, PhD, Florence Armstrong, Francoise Pflumio, paul-Henri Romeo
Journal: Blood
Blood (2008) 112 (11): 748.
https://doi.org/10.1182/blood.V112.11.748.748
Published: 2008
Journal Articles

Dynamic Change in the Stochiometry of ETO2 and SCL Governs the Transition to Terminal Differentiation in Erythroid Progenitors.

Julie A. Lambert, Nicolas Goardon, Patrick Rodriguez, Sabine Herblot, Pierre Thibault, John Strouboulis, Paul-Henri Romeo, Trang Hoang
Journal: Blood
Blood (2006) 108 (11): 1169.
https://doi.org/10.1182/blood.V108.11.1169.1169
Published: 2006
Journal Articles

Low SCL/TAL1 expression reveals its major role in adult hematopoietic myeloid progenitors and stem cells

Philippe Brunet de la Grange, Florence Armstrong, Veronique Duval, Marie-Christine Rouyez, Nicolas Goardon, Paul-Henri Romeo, Françoise Pflumio
Journal: Blood
Blood (2006) 108 (9): 2998–3004.
https://doi.org/10.1182/blood-2006-05-022988
Published: 2006
Journal Articles

Ectopic expression of TAL-1 protein in Ly-6E.1-htal-1 transgenic mice induces defects in B- and T-lymphoid differentiation

Nicolas Goardon, Annette Schuh, Iman Hajar, Xiaoqian Ma, Hélène Jouault, Elaine Dzierzak, Paul-Henri Roméo, Leı̈la Maouche-Chrétien
Journal: Blood
Blood (2002) 100 (2): 491–500.
https://doi.org/10.1182/blood.V100.2.491
Published: 2002