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Journal Articles

Addition of Rituximab Improves the Outcome of Adult Patients with CD20-Positive, Ph-Negative, B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL): Results of the Randomized Graall-R 2005 Study

Sébastien Maury, Sylvie Chevret, Xavier Thomas, Dominik Heim, Thibaut Leguay, Françoise Huguet, Patrice Chevallier, Mathilde Hunault, Nicolas Boissel, Martine Escoffre-Barbe, Urs Hess, Norbert Vey, Thorsten Braun, Jean-Pierre Marolleau, Yves Chalandon, Véronique Lhéritier, Kheira Beldjord, Marie-Christine Béné, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2015) 126 (23): 1.
https://doi.org/10.1182/blood.V126.23.1.1
Published: 2015
Journal Articles

Role of allogeneic stem cell transplantation in adult patients with Ph-negative acute lymphoblastic leukemia

CME Clinical Trials & Observations
Nathalie Dhédin, Anne Huynh, Sébastien Maury, Reza Tabrizi, Kheira Beldjord, Vahid Asnafi, Xavier Thomas, Patrice Chevallier, Stéphanie Nguyen, Valérie Coiteux, Jean-Henri Bourhis, Yosr Hichri, Martine Escoffre-Barbe, Oumedaly Reman, Carlos Graux, Yves Chalandon, Didier Blaise, Urs Schanz, Véronique Lhéritier, Jean-Yves Cahn, Hervé Dombret, Norbert Ifrah
Journal: Blood
Blood (2015) 125 (16): 2486–2496.
https://doi.org/10.1182/blood-2014-09-599894
Published: 2015
Includes: Supplemental data
Journal Articles

Value of Cytogenetic Abnormalities in Adult Patients with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) Treated in the Pediatric-Inspired Trials from the Group for Research on Adult ALL (GRAALL)

Marina Lafage-Pochitaloff, Laurence Baranger, Mathilde Hunault, Wendy Cuccuini, MD, Audrey Bidet, Nicole Dastugue, MD, Isabelle Tigaud, MD, Catherine Henry, Carine Gervais, MD, Dominique Penther, Christine Lefebvre, Nathalie Nadal, Francine Mugneret, Virginie Eclache, Isabelle Radford, Nathalie Gachard, Marie-Joelle Mozziconacci, Eric Delabesse, Marie C Bene, Agnès Chassevent, Kheira Beldjord, Vahid Asnafi, MDPhD, Françoise Huguet, Véronique Lhéritier, Norbert Ifrah, Hervé Dombret, MD PhD
Journal: Blood
Blood (2014) 124 (21): 492.
https://doi.org/10.1182/blood.V124.21.492.492
Published: 2014
Journal Articles

Outcome of Younger Adults with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) in First Relapse: A Graall Study

Alexandre Desjonqueres, resident, Patrice Chevallier, MD PhD, Xavier Thomas, MD PhD, Françoise Huguet, MD, Thibault Leguay, MD, Marc Bernard, MD, Jacques-Olivier Bay, MD PhD, Emmanuelle Tavernier, MD, Aude Charbonnier, MD, Françoise Isnard, MD, Mathilde Hunault, Pascal Turlure, MD, Marc Renaud, MD, Jean-Noel M. Bastie, MD PhD, Chantal Himberlin, MD, Stephane Lepretre, MD, Bruno Lioure, MD PhD, Véronique Lhéritier, Vahid Asnafi, Kheira Beldjord, Marina Lafage, Norbert Ifrah, Herve Dombret, MD
Journal: Blood
Blood (2014) 124 (21): 931.
https://doi.org/10.1182/blood.V124.21.931.931
Published: 2014
Journal Articles

Oncogenetics and minimal residual disease are independent outcome predictors in adult patients with acute lymphoblastic leukemia

Clinical Trials & Observations
Kheira Beldjord, Sylvie Chevret, Vahid Asnafi, Françoise Huguet, Marie-Laure Boulland, Thibaut Leguay, Xavier Thomas, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon, Nicolas Boissel, Beat Schaefer, Eric Delabesse, Hélène Cavé, Patrice Chevallier, Agnès Buzyn, Thierry Fest, Oumedaly Reman, Jean-Paul Vernant, Véronique Lhéritier, Marie C. Béné, Marina Lafage, Elizabeth Macintyre, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2014) 123 (24): 3739–3749.
https://doi.org/10.1182/blood-2014-01-547695
Published: 2014
Includes: Supplemental data
Journal Articles

Prognostic Impact Of Somatic NOTCH2 Mutation In Splenic Marginal Zone Lymphoma

Caroline Algrin, Gabriel Brisou, Kheira Beldjord, MD, PhD, Nicolas Mounier, MD, PhD, Francoise Berger, Lucile Baseggio, Aurélie Verney, Gilles Andre Salles, MD, PhD, Bertrand Coiffier, MD, PhD, Josette Briere, MD, Alexandra Traverse-Glehen, Catherine Thieblemont, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4247.
https://doi.org/10.1182/blood.V122.21.4247.4247
Published: 2013
Journal Articles

Reappraisal Of The p16 INK4A /Prb Pathway and Telomerase Activity, Markers Of Cell Activation and Aging, In Adult Acute Lymphoblastic Leukemia: A Graall Study

Martine Ffrench, MD, PhD, Wei W Chien, PhD, Régine Catallo, Amel Chebel, PhD, Laurence Baranger, MD, Xavier Thomas, MD, Marie-Christine Bene, PharmSciD, PhD, Luc M Gerland, MD, Aline Schmidt, MD, Kheira Beldjord, MD, PhD, Nathalie Klein, MD, Martine Escoffre-Barbe, Thibault Leguay, MD, Huguet Françoise, M.D., Fabrice Larosa, MD, Sandrine Hayette, PhD, Adriana Plesa, MD, Norbert Ifrah, MD, Hervé Dombret, MD, PhD, Gilles Andre Salles, MD, PhD, Agnès Chassevent, MD
Journal: Blood
Blood (2013) 122 (21): 2579.
https://doi.org/10.1182/blood.V122.21.2579.2579
Published: 2013
Journal Articles

Daunorubicin or Not During the Induction Treatment of Childhood Standard-Risk B-Cell Precursor Acute Lymphoblastic Leukemia (SR-BCP-ALL): The Randomized Fralle 2000-A Protocol

Andre Baruchel, PhD, MD, Arnaud Petit, Thierry Leblanc, Gérard Michel, Yves Perel, MD, PhD, Francoise Mechinaud, MD, Virginie Gandemer, Claudine Schmitt, MD, Pascale Schneider, Benoit Brethon, MD, Anne Auvrignon, Caroline Thomas, M.D., Geneviève Margueritte, Christiane Vermylen, MD, PhD, Odile Lejars, MD, Isabelle Pellier, Claire Berger, MD, Gérard Couillault, Catherine Paillard, Christian Berthou, MD, Christophe Piguet, MD, Brigitte Pautard, MD, Jean Soulier, MD, PhD, Nathalie Grardel, Kheira Beldjord, Marie-Francoise Auclerc, Elizabeth Macintyre, MD, PhD, Jean-Michel Cayuela, PhD, Sylvie Chevret, Guy Leverger, MD
Journal: Blood
Blood (2012) 120 (21): 135.
https://doi.org/10.1182/blood.V120.21.135.135
Published: 2012
Journal Articles

Minimal Residual Disease At 3 Months, Combined to the Presence of IKZF1 Deletion in B-Lineage or Absence of NOTCH1 pathway Mutation in T-Lineage, Recapitulates the Disease Risk Assessment in Adults with Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia - A GRAALL Study

Kheira Beldjord, Elizabeth Macintyre, Véronique Lhéritier, Marie-Laure Boulland, MD, Thibaut Leguay, MD, Xavier Thomas, MD, PhD, Jean-Michel Cayuela, Nathalie Grardel, Yves Chalandon, MD, Nicolas Boissel, Beat Schäfer, Hélène Cavé, Patrice Chevallier, Agnès Buzyn, Thierry Fest, MD, PhD, Vahid Asnafi, Oumedaly Reman, MD, Marie-Christine Béné, Françoise Huguet, MD, Sylvie Chevret, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2011) 118 (21): 572.
https://doi.org/10.1182/blood.V118.21.572.572
Published: 2011
Journal Articles

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

Anastasia Hadzidimitriou, Andreas Agathangelidis, Nikos Darzentas, Fiona Murray, Marie-Helene Delfau-Larue, Lone Bredo Pedersen, Alba Navarro Lopez, Antonis Dagklis, Paul Rombout, Kheira Beldjord, Arne Kolstad, Martin H. Dreyling, Achilles Anagnostopoulos, Athanasios Tsaftaris, Penelope Mavragani-Tsipidou, Andreas Rosenwald, Maurilio Ponzoni, Patricia Groenen, Paolo Ghia, Birgitta Sander, Theodora Papadaki, Elias Campo, Christian Geisler, Richard Rosenquist, Frederic Davi, Christiane Pott, Kostas Stamatopoulos
Journal: Blood
Blood (2011) 118 (11): 3088–3095.
https://doi.org/10.1182/blood-2011-03-343434
Published: 2011
Includes: Supplemental data
Journal Articles

R-CHOP/R-DHAP Compared to R-CHOP Induction Followed by High Dose Therapy with Autologous Stem Cell Transplantation Induces Higher Rates of Molecular Remission In MCL: Results of the MCL Younger Intergroup Trial of the European MCL Network

Christiane Pott, Eva Hoster, Kheira Beldjord, Elizabeth A. Macintyre, Sebastian Böttcher, Vahid Asnafi, Reiner Siebert, Anne Plonquet, Evelyne Callet-Bauchut, Vincent Ribrag, Wolfram Klapper, Francoise Berger, Michael Unterhalt, Michael Kneba, Wolfgang Hiddemann, Martin H. Dreyling, Olivier Hermine, Marie-Helene Delfau
Journal: Blood
Blood (2010) 116 (21): 965.
https://doi.org/10.1182/blood.V116.21.965.965
Published: 2010
Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Nicolas Goardon, Emmanuele Marchi, Lynn Quek, Anna Schuh, Petter Woll, Adam Mead, Kate Alford, Amanda Gilkes, Kheira Beldjord, David Bowen, Graham Standen, Sally Killick, Hannah Hunter, Steven Knapper, Lisa Robinson, Alex Sternberg, James D Cavenagh, Paul Virgo, Mike Griffiths, Elizabeth A. Macintyre, PhD, FRCP, FRCPath, Charles Craddock, Alan Burnett, Tariq Enver, PhD, Sten Eirik W Jacobsen, Catherine Porcher, Paresh Vyas
Journal: Blood
Blood (2010) 116 (21): 91.
https://doi.org/10.1182/blood.V116.21.91.91
Published: 2010
Journal Articles

Further Characterization of T-Cellular Precursors Generated From CD34 + Progenitors by Exposure to Immobilized Notch Ligand Delta-Like 4 In Vitro.

Christian Reimann, MD, Andrea Schiavo, Julien Rouiller, Elodie Vidal, Kheira Beldjord, MD, PhD, Liliane Dal-Cortivo, MD, PhD, Marina Cavazzana-Calvo, MD, PhD, Isabelle Andre-Schmutz, PhD
Journal: Blood
Blood (2010) 116 (21): 3712.
https://doi.org/10.1182/blood.V116.21.3712.3712
Published: 2010
Journal Articles

Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study

Clinical Trials & Observations
Christiane Pott, Eva Hoster, Marie-Helene Delfau-Larue, Kheira Beldjord, Sebastian Böttcher, Vahid Asnafi, Anne Plonquet, Reiner Siebert, Evelyne Callet-Bauchu, Niels Andersen, Jacques J. M. van Dongen, Wolfram Klapper, Françoise Berger, Vincent Ribrag, Achiel L. van Hoof, Marek Trneny, Jan Walewski, Peter Dreger, Michael Unterhalt, Wolfgang Hiddemann, Michael Kneba, Hanneke C. Kluin-Nelemans, Olivier Hermine, Elizabeth Macintyre, Martin Dreyling
Journal: Blood
Blood (2010) 115 (16): 3215–3223.
https://doi.org/10.1182/blood-2009-06-230250
Published: 2010
Includes: Supplemental data
Journal Articles

Sequence-Based Evidence for Antigen Selection in Mantle Cell Lymphoma: Remarkable Immunoglobulin Gene Repertoire Biases, Stereotyped Antigen-Binding Sites and Recurrent Hypermutations in Certain Subsets.

Anastasia Hadzidimitriou, Andreas Agathagelidis, Fiona Murray, Marie-Helene Delfau-Larue, Nikos Darzentas, Alba Navarro Lopez, Paul Rombout, Kheira Beldjord, Martin H. Dreyling, Theodora Papadaki, Achilles Anagnostopoulos, Andreas Rosenwald, Patricia Groenen, Elias Campo, Richard Rosenquist, Frederic Davi, Pr, Christiane Pott, Kostas Stamatopoulos
Journal: Blood
Blood (2009) 114 (22): 1933.
https://doi.org/10.1182/blood.V114.22.1933.1933
Published: 2009
Journal Articles

Eight Colors Flow Cytometry Phenotyping for Blood Minimal Residual Disease Monitoring in Hairy Cell Leukaemia Patients.

Marie-Olivia Chandesris, Francine Garnache, Ludovic Lhermitte, Kheira Beldjord, Anne-Sophie Bedin, Felipe Suarez, Olivier Hermine, Vahid Asnafi, Bruno Varet, Elizabeth Macintyre
Journal: Blood
Blood (2009) 114 (22): 1609.
https://doi.org/10.1182/blood.V114.22.1609.1609
Published: 2009
Journal Articles

Post-Induction Minimal Residual Disease (MRD) Defines a Large Subset of Adults with Favorable Ph-Negative Acute Lymphoblastic Leukemia (ALL), Who Do Not Benefit From Allogeneic Stem Cell Transplantation (SCT) in First Complete Remission: A GRAALL Study.

Kheira Beldjord, Véronique Lhéritier, Marie-Laure Boulland, Nathalie Grardel, Jean-Michel Cayuela, Hélène Cavé, Beat Schäfer, Marleen Bakkus, Marlène Garrido, Nathalie Dhédin, Anne Huynh, Thibaut Leguay, Claude Gardin, Xavier Thomas, Yves Chalandon, Françoise Huguet, Jean-Paul Vernant, Thierry Fest, MD, PhD, Norbert Ifrah, Elizabeth Macintyre, Hervé Dombret
Journal: Blood
Blood (2009) 114 (22): 577.
https://doi.org/10.1182/blood.V114.22.577.577
Published: 2009
Journal Articles

NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

Clinical Trials & Observations
Vahid Asnafi, Agnès Buzyn, Sandrine Le Noir, Frédéric Baleydier, Arnauld Simon, Kheira Beldjord, Oumedaly Reman, Francis Witz, Thierry Fagot, Emmanuelle Tavernier, Pascal Turlure, Thibaut Leguay, Françoise Huguet, Jean-Paul Vernant, Francis Daniel, Marie-Christine Béné, Norbert Ifrah, Xavier Thomas, Hervé Dombret, Elizabeth Macintyre
Journal: Blood
Blood (2009) 113 (17): 3918–3924.
https://doi.org/10.1182/blood-2008-10-184069
Published: 2009
Includes: Supplemental data
Journal Articles

C/EBPA methylation is common in T-ALL but not in M0 AML

Louis Terriou, Raouf Ben Abdelali, Christophe Roumier, Ludovic Lhermitte, John de Vos, Pascale Cornillet, Olivier Nibourel, Kheira Beldjord, Hervé Dombret, Guy Leverger, Vahid Asnafi, Claude Preudhomme, Elizabeth Macintyre
Journal: Blood
Blood (2009) 113 (8): 1864–1866.
https://doi.org/10.1182/blood-2008-09-176909
Published: 2009
Journal Articles

NOTCH1/FBXW7 Mutation Identifies a Large Subgroup with Favorable Outcome in Adult T-ALL: A GRAALL Study.

Vahid Asnafi, Agnes Buzyn, Sandrine Lenoir, Fréderic Baleydier, Arnauld Simon, Kheira Beldjord, Oumedaly Reman, Francis Witz, Thierry de Revel, Emmanuelle Tavernier, Pascal Turlure, Thibaut Leguay, Francoise Huguet, Jean- Paul Vernant, Veronique Lhéritier, Marie-Christine Béné, Norbert Ifrah, Xavier Thomas, Hervé Dombret, Elizabeth MacIntyre, PhD
Journal: Blood
Blood (2008) 112 (11): 1494.
https://doi.org/10.1182/blood.V112.11.1494.1494
Published: 2008