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Journal Articles

Dasatinib (Sprycel®) and Low Intensity Chemotherapy for First-Line Treatment in Patients with De Novo Philadelphia Positive ALL Aged 55 and Over: Final Results of the EWALL-Ph-01 Study

Philippe Rousselot, MD, PhD, Marie Magdeleine Coudé, Françoise Huguet, Marina Lafage, Thibaut Leguay, Celia Salanoubat, MD, Francis Witz, MD, Magda Alexis, MD, Maud Janvier, MD, Mathilde Hunault, MD, PhD, Philippe Agape, Christian Berthou, MD, Eric Jourdan, MD, José Fernandes, MD, Laurent Sutton, Anne Banos, Oumedaly Reman, MD, Bruno Lioure, MD, Jean-Michel Cayuela, PhD, Sandrine Hayette, Nicola Gokbuget, MD, Dieter Hoelzer, MD, Andre Delannoy, MD, Carlo Gambacorti-Passerini, MD, Renato Bassan, MD, Josep-Maria Ribera, MD, PhD, Sebastian Giebel, MD, Herve Dombret, Oliver G. Ottmann, MD
Journal: Blood
Blood (2012) 120 (21): 666.
https://doi.org/10.1182/blood.V120.21.666.666
Published: 2012
Journal Articles

RAD001: A Clinico-Biological Phase I GOELAMS trial of Everolimus Association with High Dose Chemotherapy in Late Relapsing AML Patients Under 65 Years of Age

Sophie Park, Nicolas Chapuis, Franck Saint Marcoux, PharmD, PhD, Christian Recher, MD, PhD, Norbert Vey, MD, Thomas Prebet, MD, PhD, Patrice Chevallier, MD, Jean-Yves Cahn, MD, Arnaud Pigneux, MD, PhD, Bruno Lioure, Francis Witz, MD, Thierry Lamy, MD, PhD, Annabelle Merlat, Roselyne Delepine, Francois Dreyfus, Marie-christine Béné, Norbert Ifrah, Didier Bouscary, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 945.
https://doi.org/10.1182/blood.V118.21.945.945
Published: 2011
Journal Articles

Addition of Gemtuzumab Ozogamycin to Chemotherapy Improves Event-Free Survival but Not Overall Survival of AML Patients with Intermediate Cytogenetics Not Eligible for Allogeneic Transplantation. Results of the GOELAMS AML 2006 IR Study

Jacques Delaunay, Christian Recher, MD, PhD, Arnaud Pigneux, MD, PhD, Francis Witz, MD, Norbert Vey, MD, Odile Blanchet, Pascale Lefebvre, Isabelle Luquet, Isabelle Guillerme, Christelle Volteau, Emmanuel Gyan, MD, PhD, Bruno Lioure, Eric Jourdan, Didier Bouscary, MD, PhD, Romain Guieze, MD, Edouard Randriamalala, Mario E Ojeda Uribe, MD, Francois Dreyfus, Catherine Lacombe, Marie-christine Béné, Jean-Yves Cahn, MD, Jean-Luc Harousseau, MD, Norbert Ifrah
Journal: Blood
Blood (2011) 118 (21): 79.
https://doi.org/10.1182/blood.V118.21.79.79
Published: 2011
Journal Articles

Dismal prognostic value of monosomal karyotype in elderly patients with acute myeloid leukemia: a GOELAMS study of 186 patients with unfavorable cytogenetic abnormalities

Clinical Trials & Observations
Aurore Perrot, Isabelle Luquet, Arnaud Pigneux, Francine Mugneret, Jacques Delaunay, Jean-Luc Harousseau, Carole Barin, Jean-Yves Cahn, Philippe Guardiola, Chantal Himberlin, Christian Recher, Norbert Vey, Bruno Lioure, Mario Ojeda-Uribe, Nathalie Fegueux, Christian Berthou, Edouard Randriamalala, Marie C. Béné, Norbert Ifrah, Francis Witz, for the GOELAMS (Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang)
Journal: Blood
Blood (2011) 118 (3): 679–685.
https://doi.org/10.1182/blood-2010-09-307264
Published: 2011
Journal Articles

Dasatinib (Sprycel®) and Low Intensity Chemotherapy for First-Line Treatment In Elderly Patients with De Novo Philadelphia Positive ALL (EWALL-PH-01): Kinetic of Response, Resistance and Prognostic Significance

Philippe Rousselot, MD, PhD, Jean Michel Cayuela, MD, PhD, Sandrine Hayette, MD, PhD, Christian Récher, MD, PhD, Thibaut Leguay, MD, Celia Salanoubat, MD, Francis Witz, MD, Magda Alexis, MD, Mathilde Hunault, MD, PhD, Maud Janvier, MD, Philippe Agape, MD, Christian Berthou, MD, PhD, Eric Jourdan, MD, José Fernandes, MD, Laurent Sutton, MD, Anne Banos, MD, Oumedaly Reman, MD, Bruno Lioure, MD, Xavier Thomas, MD, PhD, Norbert Ifrah, MD, Nicola Gokbuget, MD, Dieter Hoelzer, MD, Andre Delannoy, MD, Renato Bassan, MD, Jose M. Ribera, MD, PhD, Sebastian Giebel, MD, PhD, Herve Dombret, MD, Oliver G. Ottmann, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 172.
https://doi.org/10.1182/blood.V116.21.172.172
Published: 2010
Journal Articles

Higher incidence of relapse in patients with acute myelocytic leukemia infused with higher doses of CD34 + cells from leukapheresis products autografted during the first remission

Clinical Trials & Observations
Norbert-Claude Gorin, Myriam Labopin, Josy Reiffers, Noel Milpied, Didier Blaise, Francis Witz, Theo de Witte, Giovanna Meloni, Michel Attal, Teresa Bernal, Vanderson Rocha, for the Acute Leukemia Working Party of the European Cooperative Group for Blood and Marrow Transplantation
Journal: Blood
Blood (2010) 116 (17): 3157–3162.
https://doi.org/10.1182/blood-2009-11-252197
Published: 2010
Journal Articles

Prognostic Value of the ‘Monosomal Karyotype’ Entity in Elderly Patients with AML: a GOELAMS Study of 186 Patients with Unfavourable Cytogenetic Abnormalities.

Aurore Perrot, MD, Isabelle Luquet, MD, PhD, Arnaud Pigneux, MD, PhD, Francine Mugneret, MD, Jacques Delaunay, MD, Jean-Luc Harousseau, MD, PhD, Francis Witz, MD, Carole Barin, MD, Jean-Yves Cahn, MD, PhD, Philippe Guardiola, MD, Chantal Himberlin, MD, Christian Recher, MD, PhD, Norbert Vey, MD, Bruno Lioure, MD, Olivier Tournilhac, MD, PhD, Nathalie Fegueux, MD, Christian Berthou, MD, PhD, Martine Escoffre-Barbe, MD, Marie-Christine Béné, MD, PhD, Norbert Ifrah, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1577.
https://doi.org/10.1182/blood.V114.22.1577.1577
Published: 2009
Journal Articles

Long-Term Results of the Imatinib GRAAPH-2003 Study in Newly-Diagnosed Patients with De Novo Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia..

Aline Tanguy-Schmidt, MD, Adrienne de Labarthe, Philippe Rousselot, MD, PhD, Francoise Huguet, Eric Delabesse, PhD, Francis Witz, MD, Sebastien Maury, MD, PhD, Delphine Rea, MD, PhD, Jean-Michel Cayuela, MD, Marie-Christiane M Vekemans, Reman Oumédaly, Agnes Buzyn, Arnaud Pigneux, MD, PhD, Martine Escoffre, Yves Chalandon, Elizabeth Macintyre, MD, PhD, Jean-Paul Vernant, Xavier Thomas, MD, PhD, Norbert Ifrah, MD, Herve Dombret, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 3080.
https://doi.org/10.1182/blood.V114.22.3080.3080
Published: 2009
Journal Articles

NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study

Clinical Trials & Observations
Vahid Asnafi, Agnès Buzyn, Sandrine Le Noir, Frédéric Baleydier, Arnauld Simon, Kheira Beldjord, Oumedaly Reman, Francis Witz, Thierry Fagot, Emmanuelle Tavernier, Pascal Turlure, Thibaut Leguay, Françoise Huguet, Jean-Paul Vernant, Francis Daniel, Marie-Christine Béné, Norbert Ifrah, Xavier Thomas, Hervé Dombret, Elizabeth Macintyre
Journal: Blood
Blood (2009) 113 (17): 3918–3924.
https://doi.org/10.1182/blood-2008-10-184069
Published: 2009
Includes: Supplemental data
Journal Articles

A Randomised Phase II Study of Pegylated Liposomal Doxorubicine in Elderly Patients with Acute Lymphoblastic Leukemia (ALL): The GRAALL-SA1 Study.

Mathilde hunault-Berger, MD, PhD, Thibaut Leguay, Xavier Thomas, Ollivier Legrand, Francoise Huguet, Francis Witz, Martine Escoffre-Barbe, MD, Laurence Legros, Pascal Turlure, Patrice Chevallier, MD, Fabrice Larosa, jean-Yves Cahn, Oumedaly Reman, Philippe Rousselot, MD, PhD, Andre Delannoy, MD, Nathalie Dhedin, Marina Pochitaloff, marie-Christine Béné, Norbert Ifrah, MD, Hervé Dombret
Journal: Blood
Blood (2008) 112 (11): 918.
https://doi.org/10.1182/blood.V112.11.918.918
Published: 2008
Journal Articles

Improved Outcome by Addition of Lomustine (CCNU) to Idarubicin and Cytarabine in Elderly Patients with De Novo Acute Myeloid Leukemia. A Report from the GOELAMS Group

Arnaud Pigneux, MD, PhD, Francis Witz, Mathieu Sauvezie, Marie-Christine Bene, MD, PhD, Isabelle Luquet, MD, PhD, Mathilde hunault-Berger, MD, PhD, Christian Recher, M.D., Ph.D, Norbert Vey, MD, Bruno Lioure, MD, Chantal Himberlin, MD, Martine Escoffre-Barbe, MD, Christian Berthou, Severine Lissandre, Nathalie Fegueux, MD, Jean-Yves Cahn, MD, PhD, Eric Jourdan, MD, PhD, Didier Bouscary, MD, PhD, Francois Dreyfus, Josy M. Reiffers, Noel Milpied, MD, Jean-Luc Harousseau, MD, Norbert Ifrah, MD
Journal: Blood
Blood (2008) 112 (11): 761.
https://doi.org/10.1182/blood.V112.11.761.761
Published: 2008
Journal Articles

Immune and Cytogenetic Perturbations after G-CSF Mobilization in Normal Peripheral Blood Stem Cell Donors

Caroline Marmier-Savet, Eric Deconinck, Fabrice Larosa, Suzanne Mathieu-Nafissi, Faezeh Legrand, Brigitte Witz, Caroline Bonmati, Dana Ranta, Maribel Tavernier, Mauricette Michallet, Pascale Louvat, Marc Puyraveau, Nicole Raus, Olivier Hequet, Francis Witz, Marie-Agnes Collonge Rame, Fabienne Pouthier, Jean-Luc Bresson, Pierre Tiberghien, Eric Robinet
Journal: Blood
Blood (2008) 112 (11): 205.
https://doi.org/10.1182/blood.V112.11.205.205
Published: 2008
Journal Articles

Dasatinib (Sprycel®) and Chemotherapy for First-Line Treatment in Elderly Patients with De Novo Philadelphia Positive ALL: Results of the First 22 Patients Included in the EWALL-Ph-01 Trial (on Behalf of the European Working Group on Adult ALL (EWALL))

Philippe Rousselot, Jean-Michel Cayuela, Christian Recher, Thibaut Leguay, Célia Salanoubat, Francis Witz, Magda Alexis, Maud Janvier, Mathilde Hunault, Philippe Agape, Christian Berthou, Eric Jourdan, José Fernandes, Laurent Sutton, Anne Banos, Oumedaly Reman, Bruno Lioure, MD, Nicola Gökbuget, Dieter Hoelzer, MD, PhD, André Delannoy, Renato Bassan, Jose-Maria Ribera, Sebastian Giebel, Sandrine Hayette, Oliver Ottmann, Hervé Dombret
Journal: Blood
Blood (2008) 112 (11): 2920.
https://doi.org/10.1182/blood.V112.11.2920.2920
Published: 2008
Journal Articles

Absolute Lymphocyte Count at 1st Remission Is Prognostic Factor for Disease Free and Overall Survival for Acute Myeloid Leukemia Under 60: Analysis of AML1 GOELAMS Trial

Bruno Lioure, MD, Christian Recher, M.D., Ph.D, Patrice Chevallier, MD, Arnaud Pigneux, MD, PhD, Francis Witz, Norbert Vey, MD, Nathalie Fegueux, MD, Claude-Eric Bulabois, Sylvie Daliphard, Fabrice Larosa, Martine Escoffre-Barbe, MD, Eric Jourdan, MD, PhD, Olivier Tournilhac, MD, PhD, Martine Delain, MD, Denis Caillot, Mario Ojeda, MD, Edouard Randriamalala, MD, Roselyne Delepine, Francois Dreyfus, Norbert Ifrah, MD
Journal: Blood
Blood (2008) 112 (11): 2520.
https://doi.org/10.1182/blood.V112.11.2520.2520
Published: 2008
Journal Articles

NOTCH1/FBXW7 Mutation Identifies a Large Subgroup with Favorable Outcome in Adult T-ALL: A GRAALL Study.

Vahid Asnafi, Agnes Buzyn, Sandrine Lenoir, Fréderic Baleydier, Arnauld Simon, Kheira Beldjord, Oumedaly Reman, Francis Witz, Thierry de Revel, Emmanuelle Tavernier, Pascal Turlure, Thibaut Leguay, Francoise Huguet, Jean- Paul Vernant, Veronique Lhéritier, Marie-Christine Béné, Norbert Ifrah, Xavier Thomas, Hervé Dombret, Elizabeth MacIntyre, PhD
Journal: Blood
Blood (2008) 112 (11): 1494.
https://doi.org/10.1182/blood.V112.11.1494.1494
Published: 2008
Journal Articles

Prognosis of Patients with AML Carrying 11Q23/MLL Reciprocal Translocations : A Retrospective Study of 191 Cases from the French AML-Intergroup

Anne Banos, Antoine Jaquet, Anne Auvrignon, Nicole Dastugue, Christine Terré, Isabelle Luquet, MD, PhD, Sylvie Castaigne, Marina lafage Pochitaloff, Thierry Leblanc, Pierre Fenaux, MD, PhD, Francoise Huguet, Francis Witz, Didier Blaise, Josy M. Reiffers, Jean Luc Harousseau, Gerard Socie, MD, Bruno Lioure, MD, Christian Bastard, Herve Dombret, MD, Arnaud Pigneux, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 2547.
https://doi.org/10.1182/blood.V112.11.2547.2547
Published: 2008
Journal Articles

Core Binding Factor Acute Myeloid Leukemia of the Elderly Treated with Conventional Chemotherapy: A Collaborative Study of the French CBF AML Intergroup

Thomas Prebet, MD, Nicolas Boissel, MD, PhD, Christian Recher, MD, PhD, Xavier Thomas, MD, PhD, Jacques Delaunay, MD, Jean-Yves Cahn, MD, PhD, Arnaud Pigneux, MD, PhD, Bruno Quesnel, MD, PhD, Francis Witz, MD, Sylvain Thépot, Valérie Ugo, MD, Christine Terre, Emmanuelle Tavernier, MD, PhD, Sylvie Castaigne, MD, Francois Guilhot, MD, Hervé Dombret, Norbert Vey, MD
Journal: Blood
Blood (2008) 112 (11): 553.
https://doi.org/10.1182/blood.V112.11.553.553
Published: 2008
Journal Articles

Improved Outcome with Androgens as Maintenance Treatment in Elderly Patients with Acute Myeloid Leukemia after ICL Regimen as Induction Therapy: Results of the GOELAMS SA-2002 Multicenter Phase III Randomized Open Trial

Arnaud Pigneux, MD, PhD, Chantal Himberlin, MD, Mathilde Hunault-Berger, MD, PhD, Francis Witz, MD, Christian Recher, MD, PhD, Jean-Luc Harousseau, MD, Olivier Tournilhac, MD, PhD, Christian Berthou, MD, PhD, Martine Escoffre-Barbe, MD, Denis Guyotat, MD, PhD, Nathalie Fegueux, MD, Martine Delain, MD, Bruno Lioure, MD, Eric Jourdan, MD, PhD, Didier Bouscary, MD, PhD, Laurence Legros, MD, PhD, Noel Milpied, MD, Frederic Bauduer, MD, Frederic Perry, Isabelle Luquet, MD, PhD, Marie-Christine Bene, MD, PhD, Norbert Ifrah, MD, Jean-Jacques Sotto, MD, PhD, Philippe Guardiola, MD
Journal: Blood
Blood (2008) 112 (11): 556.
https://doi.org/10.1182/blood.V112.11.556.556
Published: 2008
Journal Articles

First Results of the GRAAPH-2005 Study in younger Adult Patients with De Novo Philadelphia Positive Acute Lymphoblastic Leukemia

Yves Chalandon, Xavier Thomas, Sandrine Hayette, Jean-Michel Cayuela, Sr., Claire Abbal, Martine Escoffre-Barbe, MD, Sebastien Maury, Stephane Lepretre, Francis Witz, Lofti Benboubker, Jean-Valère Malfuson, Thibaut Leguay, Agnes Buzyn, Veronique Lheritier, Marie-Christine Bene, Marina Lafage, Norbert Ifrah, Herve Dombret
Journal: Blood
Blood (2008) 112 (11): 12.
https://doi.org/10.1182/blood.V112.11.12.12
Published: 2008
Journal Articles

Results of the AFR07 Prospective Study in De Novo Philadelphia Positive ALL Patients Aged over 55 Years: Efficacy and Safety of a Glivec® Based Induction Followed by Maintenance Therapy with Glivec® and Pegasys®.

Philippe Rousselot, Christian Recher, Agnès Buzyn, Francis Witz, Norbert Vey, Martine Escoffre-Barbe, Olivier Legrand, Pascal Turlure, Françoise Huguet, Thibaut Leguay, Jacques Delaunay, Bruno Audhuy, Cécile Fohrer, Sébastien Maury, Sylvie Castaigne, Eric Vicaux, Hervé Dombret, Jean Michel Cayuela
Journal: Blood
Blood (2007) 110 (11): 2816.
https://doi.org/10.1182/blood.V110.11.2816.2816
Published: 2007