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Philippe Guardiola
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Journal Articles

GATA2 Expression Level in Chronic Myeloid Leukemia (CML) Patients Correlates with Their Prognostic Scores and Is Associated with Disease Stage at Diagnosis

Philippe Guardiola, MD, Corentin Orvain, Nick C.P. Cross, PhD, Martine Gardembas, MD, Marc Spentchian, MD, Estelle Pedrono, PhD, Diane Lambert, PhD, Anne Coutolleau, Anne Bouvier, MD, Odile Blanchet, MDPhD, Nicole Piard, MD, Norbert Ifrah, MD PhD, Frank Giles, MD MB, FRCPI, FRCPath, Andreas Hochhaus, MD, Jerald P. Radich, MD, Philippe Rousselot, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2768.
https://doi.org/10.1182/blood.V126.23.2768.2768
Published: 2015
Journal Articles

HFE Gene Mutation Status Predicts Response to Gemtuzumab Ozogamicin in AML

Etienne Paubelle, Alice Marceau, Florence Zylbersztejn, Mickael Dussiot, Ivan Cruz Moura, PhD, Pascale Cornillet-Lefebvre, MD, Jacques Delaunay, MD, Alan K. Burnett, Sylvie Castaigne, Philippe Guardiola, MD, Norbert Ifrah, MD PhD, Hervé Dombret, Claude Preudhomme, Robert K Hills, DPhil, Olivier Hermine
Journal: Blood
Blood (2015) 126 (23): 1307.
https://doi.org/10.1182/blood.V126.23.1307.1307
Published: 2015
Journal Articles

Safety and Long-Term Efficacy of Maintenance Therapy with Alternating Azacytidine (AZA) and Lenalidomide (Len) Cycles in Elderly (≥ 60) Fit Patients (Pts) with Poor Prognosis AML in First Complete Remission (CR) After LIA Induction. A Phase II Multicentric GOELAMS Trial

Mathilde Hunault, MD PhD, Nathalie Maillard, MD, Aline Tanguy-Schmidt, MD, Chantal Himberlin, MD, Bachra Choufi, MD, Caroline Bonmati, MD, Marie Anne Couturier, MD, Eric Deconinck, MD PhD, Jean Pierre Marolleau, MD PhD, Frédérique Orsini-Piocelle, MD, Jacques Delaunay, MD, Emmanuelle Tavernier, MD, Christian Récher, MDPhD, Severine Lissandre, MD, Mario Ojeda-Uribe, MD, Laurence Sanhes, MD, Laurent Sutton, MD, Anne Banos, MD, Bruno Lioure, MD, Marc Bernard, MD, Didier Bouscary, MDPhD, Alain Saad, MD, Valérie Rouille, Philippe Guardiola, MD, Isabelle Luquet, MD, Marie C Bene, PharmSciD, PhD, Francois Dreyfus, MD, Jean-Yves Cahn, MD, Arnaud Pigneux, Norbert Ifrah, MD
Journal: Blood
Blood (2015) 126 (23): 3787.
https://doi.org/10.1182/blood.V126.23.3787.3787
Published: 2015
Journal Articles

The Number of Organ Failures, but Not Graft-Versus-Host Disease, Determines Outcome of Allogeneic Stem Cell Transplantation Recipients Requiring Intensive Care

Corentin Orvain, Francois Beloncle, MD, Sylvain Thepot, MD, Achille Kouatchet, MD, Sylvie Francois, MD, Philippe Guardiola, MDPhD, Anne Corby, MD, Pierre Asfar, MDPhD, Mathilde Hunault-Berger, MDPhD, Norbert Ifrah, MDPhD, Aline Tanguy-Schmidt, MD
Journal: Blood
Blood (2014) 124 (21): 2465.
https://doi.org/10.1182/blood.V124.21.2465.2465
Published: 2014
Journal Articles

Impact of High Body Surface Area on AML Outcome in Younger Patients: A Goelams Study

Xavier Cahu, MD, Martin Carre, MD, Christian Recher, MD, Emmanuel Gyan, MD PhD, Jean-Francois Hamel, Arnaud Pigneux, MD PhD, Norbert Vey, MD PhD, Philippe Guardiola, MD, Jacques Delaunay, MD, Eric Jourdan, MD PhD, Bruno Lioure, Marie-Christine Bene, MD, Norbert Ifrah, Jean-Yves Cahn
Journal: Blood
Blood (2014) 124 (21): 973.
https://doi.org/10.1182/blood.V124.21.973.973
Published: 2014
Journal Articles

Maintenance Therapy With Alternating Azacytidine and Lenalidomide Cycles In Elderly (≥ 60) Fit Patients (Pts) With Poor Prognosis AML In First Complete Remission (CR) After Lia Induction. A Phase II Multicentric Goelams Trial

Mathilde Hunault-Berger, MD, PhD, Edouard Randriamalala, MD, Aline Schmidt-Tanguy, MD, Chantal Himberlin, MD, Bachra Choufi, MD, Caroline Bonmati, MD, Jean Yves Cahn, MD, MD marie-Anne Couturier, Eric Deconinck, MD, PhD, Jean Pierre Marolleau, MD, PhD, Frederique orisni-Piocelle, MD, Jacques Delaunay, MD, Emmanuelle Tavernier, MD, Christian Recher, MD PhD, Severine Lissandre, MD, Mario Ojeda-Uribe, MD, Laurence Sanhes, MD, Laurent Sutton, MD, Anne Banos, MD, Bruno Lioure, MD, Thierry Lamy, MD, PhD, Didier Bouscary, MD, Alain Saad, MD, Valérie Rouille, Philippe Guardiola, MD, Isabelle Luquet, MD, MD marie-Christine Bene, Francois Dreyfus, MD, Norbert Ifrah, MD, Arnaud Pigneux, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2691.
https://doi.org/10.1182/blood.V122.21.2691.2691
Published: 2013
Journal Articles

Prospective evaluation of gene mutations and minimal residual disease in patients with core binding factor acute myeloid leukemia

Clinical Trials & Observations
Eric Jourdan, Nicolas Boissel, Sylvie Chevret, Eric Delabesse, Aline Renneville, Pascale Cornillet, Odile Blanchet, Jean-Michel Cayuela, Christian Recher, Emmanuel Raffoux, Jacques Delaunay, Arnaud Pigneux, Claude-Eric Bulabois, Céline Berthon, Cécile Pautas, Norbert Vey, Bruno Lioure, Xavier Thomas, Isabelle Luquet, Christine Terré, Philippe Guardiola, Marie C. Béné, Claude Preudhomme, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2013) 121 (12): 2213–2223.
https://doi.org/10.1182/blood-2012-10-462879
Published: 2013
Includes: Supplemental data
Journal Articles

Outcome and Prognostic Factors in Patients with Mantle Cell Lymphoma Relapsing After Autologous Stem Cell Transplantation: A Retrospective Study of the EBMT

Sascha Dietrich, MD, Herve Finel, Ariane Boumendil, Irit Avivi, MD, Liisa Volin, Jan Cornelissen, MD, PhD, Jan Walewski, Christoph Schmid, Theo M. de Witte, Harry C. Schouten, MD, PhD, Martin Kaufmann, MD, Catherine Sebban, MD, Marek Trneny, MD, Guido Kobbe, MD, Philippe Guardiola, Johannes Schetelig, MD, Michael Pfreundschuh, MD, Jose L. Diez-Martin, MD, PhD, Dominique Bordessoule, MD, PhD, Stephen Robinson, MBBS, MRCP, FRCPath, PhD, Peter Dreger, MD
Journal: Blood
Blood (2012) 120 (21): 474.
https://doi.org/10.1182/blood.V120.21.474.474
Published: 2012
Journal Articles

Gene Mutations and Minimal Residual Disease (MRD) As Predictors of Remission Duration in Adults with Core Binding Factor (CBF) Acute Myeloid Leukemia (AML) Treated with High-Dose Cytarabine (HDAC) - First Results of the Prospective French Intergroup CBF-2006 Trial

Eric Jourdan, Nicolas Boissel, Odile Blanchet, Aline Renneville, Christian Recher, MD, PhD, Emmanuel Raffoux, MD, PhD, Pascale Cornillet-Lefebvre, Jean-Michel Cayuela, Jacques Delaunay, Arnaud Pigneux, MD, PhD, Eric Delabesse, Claude-Eric Bulabois, Céline Berthon, Cécile Pautas, Norbert Vey, MD, Bruno Lioure, Xavier Thomas, Nathalie Contentin, Edouard Randriamalala, Nathalie Fegueux, Marie-Christine Béné, Julie Lejeune, Philippe Guardiola, Claude Preudhomme, Norbert Ifrah, Hervé Dombret
Journal: Blood
Blood (2011) 118 (21): 410.
https://doi.org/10.1182/blood.V118.21.410.410
Published: 2011
Journal Articles

Prognostic DNA methylation patterns in cytogenetically normal acute myeloid leukemia are predefined by stem cell chromatin marks

Stefan Deneberg, Philippe Guardiola, Andreas Lennartsson, Ying Qu, Verena Gaidzik, Odile Blanchet, Mohsen Karimi, Sofia Bengtzén, Hareth Nahi, Bertil Uggla, Ulf Tidefelt, Martin Höglund, Christer Paul, Karl Ekwall, Konstanze Döhner, Sören Lehmann
Journal: Blood
Blood (2011) 118 (20): 5573–5582.
https://doi.org/10.1182/blood-2011-01-332353
Published: 2011
Includes: Supplemental data
Journal Articles

Dismal prognostic value of monosomal karyotype in elderly patients with acute myeloid leukemia: a GOELAMS study of 186 patients with unfavorable cytogenetic abnormalities

Clinical Trials & Observations
Aurore Perrot, Isabelle Luquet, Arnaud Pigneux, Francine Mugneret, Jacques Delaunay, Jean-Luc Harousseau, Carole Barin, Jean-Yves Cahn, Philippe Guardiola, Chantal Himberlin, Christian Recher, Norbert Vey, Bruno Lioure, Mario Ojeda-Uribe, Nathalie Fegueux, Christian Berthou, Edouard Randriamalala, Marie C. Béné, Norbert Ifrah, Francis Witz, for the GOELAMS (Groupe Ouest-Est des Leucémies Aiguës et Maladies du Sang)
Journal: Blood
Blood (2011) 118 (3): 679–685.
https://doi.org/10.1182/blood-2010-09-307264
Published: 2011
Journal Articles

Are Microarray-Derived Gene Expression Signatures Useful as a Routine Assay for Prognostic Evaluation of Acute Myeloid Leukemia Samples with Low Leukemic Blast Content ?.

Philippe Guardiola, MD, Diane Lambert, PhD, Pascale Cornillet-Lefebvre, MD, PhD, Anne Coutolleau, Laurence Baranger, MD, Franck Genevieve, MD, PhD, Isabelle Luquet, MD, PhD, Annaelle Beucher, Marc Zandecki, PhD, Norbert Ifrah, MD, Odile Blanchet, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 1658.
https://doi.org/10.1182/blood.V116.21.1658.1658
Published: 2010
Journal Articles

SNP-Arrays: a Routine Cytogenetic Tool In Chronic Lymphocytic Leukemia ?.

Alban Godon, MD, Franck Genevieve, MD, Malgorzata Truchan-Graczyk, MD, Laurence Baranger, MD, Virginie Eclache, MD, Anne Coutolleau, Norbert Ifrah, MD, PhD, Marc Zandecki, MD, PhD, Philippe Guardiola, MD
Journal: Blood
Blood (2010) 116 (21): 4611.
https://doi.org/10.1182/blood.V116.21.4611.4611
Published: 2010
Journal Articles

Prognostic Value of the ‘Monosomal Karyotype’ Entity in Elderly Patients with AML: a GOELAMS Study of 186 Patients with Unfavourable Cytogenetic Abnormalities.

Aurore Perrot, MD, Isabelle Luquet, MD, PhD, Arnaud Pigneux, MD, PhD, Francine Mugneret, MD, Jacques Delaunay, MD, Jean-Luc Harousseau, MD, PhD, Francis Witz, MD, Carole Barin, MD, Jean-Yves Cahn, MD, PhD, Philippe Guardiola, MD, Chantal Himberlin, MD, Christian Recher, MD, PhD, Norbert Vey, MD, Bruno Lioure, MD, Olivier Tournilhac, MD, PhD, Nathalie Fegueux, MD, Christian Berthou, MD, PhD, Martine Escoffre-Barbe, MD, Marie-Christine Béné, MD, PhD, Norbert Ifrah, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 1577.
https://doi.org/10.1182/blood.V114.22.1577.1577
Published: 2009
Journal Articles

TET2 mutation is an independent favorable prognostic factor in myelodysplastic syndromes (MDSs)

Olivier Kosmider, Véronique Gelsi-Boyer, Meyling Cheok, Sophie Grabar, Véronique Della-Valle, Françoise Picard, Franck Viguié, Bruno Quesnel, Odile Beyne-Rauzy, Eric Solary, Norbert Vey, Mathilde Hunault-Berger, Pierre Fenaux, Véronique Mansat-De Mas, Eric Delabesse, Philippe Guardiola, Catherine Lacombe, William Vainchenker, Claude Preudhomme, François Dreyfus, Olivier A. Bernard, Daniel Birnbaum, Michaëla Fontenay, on behalf of the Groupe Francophone des Myélodysplasies
Journal: Blood
Blood (2009) 114 (15): 3285–3291.
https://doi.org/10.1182/blood-2009-04-215814
Published: 2009
Includes: Supplemental data
Journal Articles

Improved Outcome with Androgens as Maintenance Treatment in Elderly Patients with Acute Myeloid Leukemia after ICL Regimen as Induction Therapy: Results of the GOELAMS SA-2002 Multicenter Phase III Randomized Open Trial

Arnaud Pigneux, MD, PhD, Chantal Himberlin, MD, Mathilde Hunault-Berger, MD, PhD, Francis Witz, MD, Christian Recher, MD, PhD, Jean-Luc Harousseau, MD, Olivier Tournilhac, MD, PhD, Christian Berthou, MD, PhD, Martine Escoffre-Barbe, MD, Denis Guyotat, MD, PhD, Nathalie Fegueux, MD, Martine Delain, MD, Bruno Lioure, MD, Eric Jourdan, MD, PhD, Didier Bouscary, MD, PhD, Laurence Legros, MD, PhD, Noel Milpied, MD, Frederic Bauduer, MD, Frederic Perry, Isabelle Luquet, MD, PhD, Marie-Christine Bene, MD, PhD, Norbert Ifrah, MD, Jean-Jacques Sotto, MD, PhD, Philippe Guardiola, MD
Journal: Blood
Blood (2008) 112 (11): 556.
https://doi.org/10.1182/blood.V112.11.556.556
Published: 2008
Journal Articles

FOXC1, a New Prognostic Marker in Adult Acute Myeloid Leukemia (AML).

Odile Blanchet, MD, PhD, Frederique Galopin, MD, Derek Stirewalt, MD, Mathilde Hunault-Berger, MD, PhD, Annaelle Beucher, Era Pogosova-Agadjanyan, Lejla Ibricevic, MD, Laurence Baranger, MD, Franck Genevieve, MD, Marc Zandecki, MD, PhD, Norbert Ifrah, MD, Jerald P. Radich, MD, Philippe Guardiola, MD
Journal: Blood
Blood (2007) 110 (11): 2387.
https://doi.org/10.1182/blood.V110.11.2387.2387
Published: 2007
Journal Articles

Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway

Clinical Trials & Observations
Jean Soulier, Thierry Leblanc, Jérôme Larghero, Hélène Dastot, Akiko Shimamura, Philippe Guardiola, Hélène Esperou, Christèle Ferry, Charlotte Jubert, Jean-Paul Feugeas, Annie Henri, Antoine Toubert, Gérard Socié, André Baruchel, François Sigaux, Alan D. D'Andrea, Eliane Gluckman
Journal: Blood
Blood (2005) 105 (3): 1329–1336.
https://doi.org/10.1182/blood-2004-05-1852
Published: 2005
Journal Articles

Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood

Rima Haddad, Philippe Guardiola, Brigitte Izac, Christelle Thibault, Jerry Radich, Anne-Lise Delezoide, Claude Baillou, François M. Lemoine, Jean Claude Gluckman, Françoise Pflumio, Bruno Canque
Journal: Blood
Blood (2004) 104 (13): 3918–3926.
https://doi.org/10.1182/blood-2004-05-1845
Published: 2004
Includes: Supplemental data
Journal Articles

Allogeneic Stem Cell Transplantation from Unrelated Donors after Reduced Intensity Conditioning in Patients with MDS/sAML. A Report from the Chronic Leukemia Working Party (CLWP) of the EBMT.

Nicolaus Kroeger, MD, Ronald Brand, PhD, Rodrigo Martino, MD, Philippe Guardiola, MD, Anja van Biezen, Axel Zander, MD, Dietger Niederwieser, MD, Theo De Witte, MD
Journal: Blood
Blood (2004) 104 (11): 5176.
https://doi.org/10.1182/blood.V104.11.5176.5176
Published: 2004