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Journal Articles

Cyclin D1 Overexpression in Mantle Cell Lymphoma Causes Cellular Dependence on Microhomology-Mediated End-Joining

Jithma P Abeykoon, Shuhei Asada, Guangli Zu, Yuna Hirohashi, Divya Iyer, Kalindi Parmar, Lige Jiang, Sirisha Mukkavalli, Dongni Yi, Michelle Manske, Xiaosheng Wu, Kimberly Gwin, Thomas E. Witzig, Geoffrey I Shapiro, Alan D. D'Andrea

Blood (2024) 144 (Supplement 1): 2747.

https://doi.org/10.1182/blood-2024-205197

Published: 2024

Journal Articles

Metformin for Treatment of Cytopenias in Children and Young Adults with Fanconi Anemia

Blood (2021) 138 (Supplement 1): 1102.

https://doi.org/10.1182/blood-2021-153598

Published: 2021

Journal Articles

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

Blood (2018) 132 (Supplement 1): 940.

https://doi.org/10.1182/blood-2018-99-117480

Published: 2018

Journal Articles

The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia

Blood (2017) 130 (Supplement 1): 2722.

https://doi.org/10.1182/blood.V130.Suppl_1.2722.2722

Published: 2017

Journal Articles

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

Kevin O'Connor, Sofia Vidal-Cardenas, PhD, Haojian Zhang, PhD, Alfredo Rodriguez, Lisa Moreau, Chunyu Yang, Michael W Epperly, PhD, Markus Grompe, MD, Akiko Shimamura, MD PhD, Joel S. Greenberger, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD

Blood (2016) 128 (22): 1039.

https://doi.org/10.1182/blood.V128.22.1039.1039

Published: 2016

Journal Articles

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, Alix Rousseau, Lisa Moreau, Emily Gaudiano, BS, Joel S Greenberger, MD, Grover C. Bagby, Jr., MD MACP, Jean Soulier, MD PhD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D D'Andrea, MD

Blood (2015) 126 (23): 297.

https://doi.org/10.1182/blood.V126.23.297.297

Published: 2015

Journal Articles

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Haojian Zhang, PhD, David Kozono, MD PhD, Kevin O'Connor, BA, Sofia Vidal-Cardenas, PhD, Abigail Hamilton, BA, Emily Gaudiano, BS, Joel S. Greenberger, MD, Markus Grompe, MD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD

Blood (2014) 124 (21): 356.

https://doi.org/10.1182/blood.V124.21.356.356

Published: 2014

Journal Articles

Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity

Helena Mistry, Ph.D., Grace Hsieh, M.D., Sara Buhrlage, Ph.D, Min Huang, Ph.D., Eunmi Park, Ph.D., Gregory Cuny, Ph.D., Ilene Galinsky, ANP, Richard M. Stone, MD, Nathanael S Gray, PhD, Kalindi Parmar, PhD, Alan D. D'Andrea, MD

Blood (2013) 122 (21): 2906.

https://doi.org/10.1182/blood.V122.21.2906.2906

Published: 2013

Journal Articles

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Nate Russell, Trevor Taylor, Kalindi Parmar, PhD, Alan D. D'Andrea, MD, Bradley B Brasher, Ph.D., Francesco D Melandri

Blood (2013) 122 (21): 4224.

https://doi.org/10.1182/blood.V122.21.4224.4224

Published: 2013

Journal Articles

Fanconi Anemia: Emerging Therapeutic Opportunities

Markus Grompe, MD, John Postlethwait, Professor, Alan D. D'Andrea, MD, Susan B. Olson, Qingshuo Zhang, Grover C. Bagby, Jr.

Blood (2012) 120 (21): SCI-1.

https://doi.org/10.1182/blood.V120.21.SCI-1.SCI-1

Published: 2012

Journal Articles

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Lars Mueller, MD, Michael D. Milsom, PhD, Chad Harris, Rutesh Vyas, Kristina Brumme, Kalindi Parmar, PhD, Axel Schambach, MD PhD, Elke Grassman, Ph.D., In-Hyun Park, PhD, London Wendy, PhD, Kelly Strait, Thorsten Schlaeger, Ph.D, Alexander L. Devine, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2011) 118 (21): 672.

https://doi.org/10.1182/blood.V118.21.672.672

Published: 2011

Journal Articles

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Lars Mueller, MD, Michael D. Milsom, PhD, Kristina Brumme, Chad Harris, Kalindi Parmar, PhD, Kaya Zhu, London Wendy, PhD, Kelly Strait, Alan D. D'Andrea, MD, George Q. Daley, MD, PhD, David A. Williams, MD

Blood (2010) 116 (21): 196.

https://doi.org/10.1182/blood.V116.21.196.196

Published: 2010

Journal Articles

Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells

Kalindi Parmar, Ph.D, Patrizia Vinciguerra, Ph.D., Susana Godinho, Ph.D., Abigail Hamilton, BA, David Pellman, MD, Alan D. D'Andrea, MD

Blood (2010) 116 (21): 878.

https://doi.org/10.1182/blood.V116.21.878.878

Published: 2010

Journal Articles

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Kalindi Parmar, PhD, Jung Min Kim, PhD, Akiko Shimamura, MD, PhD, Anna Stuckert, Mary K DeLoach, Kaya Zhu, Peter M. Mauch, MD, Jeffery Kutok, MD, PhD, Jon Aster, MD, PhD, Koichi Akashi, MD, PhD, D. Gary Gilliland, MD, PhD, Alan D. D’Andrea, MD

Blood (2008) 112 (11): 440.

https://doi.org/10.1182/blood.V112.11.440.440

Published: 2008

Journal Articles

Cell cycle–dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

Jung Min Kim, Younghoon Kee, Allan Gurtan, Alan D. D'Andrea

Blood (2008) 111 (10): 5215–5222.

https://doi.org/10.1182/blood-2007-09-113092

Published: 2008

Includes: Supplemental data

Journal Articles

The IL-2 Induced De-Ubiquitinating Enzyme, DUB-2, Is a Nuclear-Cytoplasmic Shuttle Which Requires Catalytic Activity for Nuclear Localization.

Paul J. Galardy, MD, Alan D. D’Andrea, M.D., Hidde L. Ploegh, Ph.D.

Blood (2006) 108 (11): 868.

https://doi.org/10.1182/blood.V108.11.868.868

Published: 2006

Journal Articles

Molecular pathogenesis of Fanconi anemia: recent progress

Toshiyasu Taniguchi, Alan D. D'Andrea

Blood (2006) 107 (11): 4223–4233.

https://doi.org/10.1182/blood-2005-10-4240

Published: 2006

Journal Articles

Functional Interaction between FANCD2 and ATM in the DNA Damage Response.

Steven P. Margossian, MD, PhD, Gary Ho, Richard Kennedy, MD, PhD, Alan D. D’Andrea, MD

Blood (2005) 106 (11): 181.

https://doi.org/10.1182/blood.V106.11.181.181

Published: 2005

Journal Articles

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

Rocio Montes de Oca, Paul R. Andreassen, Steven P. Margossian, Richard C. Gregory, Toshiyasu Taniguchi, XiaoZhe Wang, Scott Houghtaling, Markus Grompe, Alan D. D'Andrea

Blood (2005) 105 (3): 1003–1009.

https://doi.org/10.1182/blood-2003-11-3997

Published: 2005

Journal Articles

Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway

Jean Soulier, Thierry Leblanc, Jérôme Larghero, Hélène Dastot, Akiko Shimamura, Philippe Guardiola, Hélène Esperou, Christèle Ferry, Charlotte Jubert, Jean-Paul Feugeas, Annie Henri, Antoine Toubert, Gérard Socié, André Baruchel, François Sigaux, Alan D. D'Andrea, Eliane Gluckman

Blood (2005) 105 (3): 1329–1336.

https://doi.org/10.1182/blood-2004-05-1852

Published: 2005

NARROW

Cyclin D1 Overexpression in Mantle Cell Lymphoma Causes Cellular Dependence on Microhomology-Mediated End-Joining

Metformin for Treatment of Cytopenias in Children and Young Adults with Fanconi Anemia

STAG2 Mutations Alter Cohesin Ring Function and Provide Therapeutic Vulnerabilities in Acute Myeloid Leukemia

The Fanconi Pathway in Pediatric T-Cell Acute Lymphoblastic Leukemia

Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression

TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia

Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling

Small Molecule Inhibitors of USP1 Target ID1 Degradation in Leukemic Cells and Cause Cytotoxicity

Characterization Of Full-Length, Recombinant Amsh, USP9x, and USP1: Clinically-Relevant Deubiquitinases Involved In Hematological Malignancies

Fanconi Anemia: Emerging Therapeutic Opportunities

Gene-Correction Rescues Reprogramming of Fanconi Anemia Fibroblasts and Enables Hematopoietic Differentiation of FA Induced Pluripotent Stem Cells in Vitro and In Vivo

Mechanisms of Resistance to Reprogramming of Cells Defective In the Fanconi Anemia DNA Repair Pathway

Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells

Hematopoietic Stem Cell Defects in Novel Fanconi Anemia Mouse Models

Cell cycle–dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

The IL-2 Induced De-Ubiquitinating Enzyme, DUB-2, Is a Nuclear-Cytoplasmic Shuttle Which Requires Catalytic Activity for Nuclear Localization.

Molecular pathogenesis of Fanconi anemia: recent progress

Functional Interaction between FANCD2 and ATM in the DNA Damage Response.

Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin

Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway

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American Society of Hematology

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American Society of Hematology

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