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Isabelle Radford
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Journal Articles

Genetic characterization of B-cell prolymphocytic leukemia: a prognostic model involving MYC and TP53

CME
Elise Chapiro, Elodie Pramil, M’boyba Diop, Damien Roos-Weil, Clémentine Dillard, Clémentine Gabillaud, Karim Maloum, Catherine Settegrana, Lucile Baseggio, Jean-François Lesesve, Mélanie Yon, Ludovic Jondreville, Claude Lesty, Frédéric Davi, Magali Le Garff-Tavernier, Nathalie Droin, Philippe Dessen, Caroline Algrin, Véronique Leblond, Jean Gabarre, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, Christine Lefebvre, Nathalie Nadal, Antoine Ittel, Stéphanie Struski, Marie-Agnès Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, Santos A. Susin, Olivier A. Bernard, Florence Nguyen-Khac
Journal: Blood
Blood (2019) 134 (21): 1821–1831.
https://doi.org/10.1182/blood.2019001187
Published: 2019
Includes: Supplemental data
Journal Articles

Combination of the MEK Inhibitor Trametinib and Pyrvinium Pamoate Efficiently Targets RAS Pathway-Mutated Acute Myeloid Leukemia in Preclinical Models

Justine Decroocq, MD, Rudy Birsen, MD, Jordi Mano, MSc, Guillemette Fouquet, Mathilde Gotanègre, MSc, Laury Poulain, PhD, Sarah Mouche, Anne-Sophie Alary, Adrien Grenier, MD PhD, Fetta Mazed, PhD, Johanna Mondesir, MD, Nicolas Chapuis, PharmD, PhD, Aicha Boughalem, MD, Marc Le Lorc'h, Ivan C Moura, PhD, Olivier Hermine, MD PhD, Isabelle Radford-Weiss, Jean-Emmanuel Sarry, PhD, Eric Pasmant, MD PhD, Olivier Kosmider, PharmD, PhD, Didier Bouscary, MD PhD, Jerome Tamburini, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2671.
https://doi.org/10.1182/blood-2019-123418
Published: 2019
Journal Articles

Genetic Characterization of B-Cell Prolymphocytic Leukemia (B-PLL): A Hierarchical Prognostic Model Involving MYC and TP53 Abnormalities. on Behalf of the Groupe Francophone De Cytogenetique Hematologique (GFCH) and the French Innovative Leukemia Organization (FILO) Group

Elise Chapiro, MD PhD, Damien Roos-Weil, MD, Nadia Bougacha, Clementine Gabillaud, Clémentine Dillard, Elodie Pramil, Melanie Yon, Karim Maloum, MD PhD, Catherine Settegrana, Lucile Baseggio, MD, Claude Lesty, Frederic Davi, MD PhD, Magali Le Garff-Tavernier, M'boyba Khadija Diop, Nathalie M Droin, PhD, Philippe Dessen, Veronique Leblond, Caroline Algrin, Simon Bouzy, Virginie Eclache, Baptiste Gaillard, Evelyne Callet-Bauchu, Marc Muller, MD, Christine Lefebvre, MD PhD, Nathalie Nadal, Antoine Ittel, PharmD, Stéphanie Struski, Marie-Agnes Collonge-Rame, Benoit Quilichini, Sandra Fert-Ferrer, Nathalie Auger, Isabelle Radford-Weiss, Lena Wagner, Sebastian Scheinost, Thorsten Zenz, MD, Santos Susin, Olivier Bernard, Florence Nguyen-Khac, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 943.
https://doi.org/10.1182/blood-2018-99-115085
Published: 2018
Journal Articles

Clonal B-Cell Lymphocytosis with Marginal Zone Features and Splenic Marginal Zone Lymphoma Share a Similar Cytogenetic and Mutational Profile

Paul Legendre, MD, Olivier Kosmider, PharmD, PhD, Coralie Derrieux, PharmD, Nicolas Chapuis, PharmD, PhD, Isabelle Radford-Weiss, PharmD, Hélène Guermouche, Barbara Burroni, MD, Julie Bruneau, MD PhD, Bénédicte Deau, MD, Richard Delarue, MD, Olivier Hermine, MD PhD, Didier Bouscary, MD PhD, David Sibon, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2962.
https://doi.org/10.1182/blood.V128.22.2962.2962
Published: 2016
Journal Articles

An Early Thymic Precursor Phenotype Predicts Outcome Exclusively in HOXA-Overexpressing Adult T-ALL: A GRAALL Study

Jonathan Bond, MDPhD, Tony Marchand, MD, Aurore Touzart, MD, Agata Cieslak, Amélie Trinquand, MD, Laurent Sutton, MD, Isabelle Radford-Weiss, Salvatore Spicuglia, PhD, Hervé Dombret, MD, Elizabeth Macintyre, MD PhD, Norbert Ifrah, MD, Jean-François Hamel, Vahid Asnafi, MDPhD
Journal: Blood
Blood (2015) 126 (23): 808.
https://doi.org/10.1182/blood.V126.23.808.808
Published: 2015
Journal Articles

Value of Cytogenetic Abnormalities in Adult Patients with Philadelphia Chromosome (Ph)-Negative Acute Lymphoblastic Leukemia (ALL) Treated in the Pediatric-Inspired Trials from the Group for Research on Adult ALL (GRAALL)

Marina Lafage-Pochitaloff, Laurence Baranger, Mathilde Hunault, Wendy Cuccuini, MD, Audrey Bidet, Nicole Dastugue, MD, Isabelle Tigaud, MD, Catherine Henry, Carine Gervais, MD, Dominique Penther, Christine Lefebvre, Nathalie Nadal, Francine Mugneret, Virginie Eclache, Isabelle Radford, Nathalie Gachard, Marie-Joelle Mozziconacci, Eric Delabesse, Marie C Bene, Agnès Chassevent, Kheira Beldjord, Vahid Asnafi, MDPhD, Françoise Huguet, Véronique Lhéritier, Norbert Ifrah, Hervé Dombret, MD PhD
Journal: Blood
Blood (2014) 124 (21): 492.
https://doi.org/10.1182/blood.V124.21.492.492
Published: 2014
Journal Articles

A Mendelian predisposition to B-cell lymphoma caused by IL-10R deficiency

Bénédicte Neven, Emilie Mamessier, Julie Bruneau, Sophie Kaltenbach, Daniel Kotlarz, Felipe Suarez, Julien Masliah-Planchon, Katy Billot, Danielle Canioni, Pierre Frange, Isabelle Radford-Weiss, Vahid Asnafi, Dhaarini Murugan, Christine Bole, Patrick Nitschke, Olivier Goulet, Jean-Laurent Casanova, Stéphane Blanche, Capucine Picard, Olivier Hermine, Frederic Rieux-Laucat, Nicole Brousse, Frederic Davi, Véronique Baud, Christoph Klein, Bertrand Nadel, Frank Ruemmele, Alain Fischer
Journal: Blood
Blood (2013) 122 (23): 3713–3722.
https://doi.org/10.1182/blood-2013-06-508267
Published: 2013
Includes: Supplemental data
Journal Articles

NOTCH1 Mutations Are Associated With The 14q Deletion In Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL)

Florence Nguyen-Khac, MD, PhD, Adrien Cosson, Elise Chapiro, Nabila Belhouachi, hong-Anh Cung, Boris Keren, Frederik Damm, MD, Caroline Algrin, Christine Lefebvre, Sandra fert-Ferrer, Isabelle Luquet, MD, Nathalie Gachard, PhD, Francine Mugneret, Christine Terré, Marie-Agnes Collonge-Rame, Lucienne Michaux, MD PhD, Isabelle Radford-Weiss, Pascaline Talmant, Lauren Veronese, MD, PhD, Nathalie Nadal, Stephanie Struski, Carole Barin, Catherine Helias, Marina Lafage, Éric Lippert, MD, PhD, Nathalie Auger, M.D., Virginie Eclache, MD, Catherine Settegrana, MD, Karim Maloum, MD, PhD, CLaude Lesty, Frederic Davi, MD, PhD, Hélène Merle-Beral, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 2561.
https://doi.org/10.1182/blood.V122.21.2561.2561
Published: 2013
Journal Articles

Enteropathy-Associated T-Cell Lymphoma Type I, But Not Refractory Celiac Disease, Strongly Expresses CD30 and Might Benefit From Brentuximab Vedotin

David Sibon, MD, PhD, Georgia Malamut, MD, PhD, Virginie Verkarre, MD, PhD, Coralie Derrieux, MD, Isabelle Radford, MD, Bertrand Meresse, PhD, Elizabeth Macintyre, MD, PhD, Christophe Cellier, MD, PhD, Nadine Cerf-Bensussan, MD, PhD, Nicole Brousse, M.D., Olivier Hermine
Journal: Blood
Blood (2013) 122 (21): 4252.
https://doi.org/10.1182/blood.V122.21.4252.4252
Published: 2013
Journal Articles

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia

Lise Willems, Nathalie Jacque, Arnaud Jacquel, Nathalie Neveux, Thiago Trovati Maciel, Mireille Lambert, Alain Schmitt, Laury Poulain, Alexa S. Green, Madalina Uzunov, Olivier Kosmider, Isabelle Radford-Weiss, Ivan Cruz Moura, Patrick Auberger, Norbert Ifrah, Valérie Bardet, Nicolas Chapuis, Catherine Lacombe, Patrick Mayeux, Jérôme Tamburini, Didier Bouscary
Journal: Blood
Blood (2013) 122 (20): 3521–3532.
https://doi.org/10.1182/blood-2013-03-493163
Published: 2013
Includes: Supplemental data
Journal Articles

Targeted Therapy in CMML: Complete Molecular Response to Sorafenib in a Patient with a FLT3-ITD Malignant Hematopoiesis

Olivier Kosmider, MD, PhD, Nicolas Chapuis, Sophie Kaltenbach, Romain Coriat, Pascaline boudou-Rouquette, Lise Willems, Virginie Chesnais, Isabelle Radford-Weiss, Valérie Bardet, Patrick Mayeux, Jerome Tamburini, Michaela Fontenay, MD, PhD, Didier Bouscary
Journal: Blood
Blood (2012) 120 (21): 4786.
https://doi.org/10.1182/blood.V120.21.4786.4786
Published: 2012
Journal Articles

A Mendelian Predisposition to B Cell Lymphoma Caused by IL-10R2 Deficiency

Benedicte Neven, Emilie Mamessier, Julie Bruneau, Sophie Kaltenbach, Felipe Suarez, MD, PhD, Francois Doz, Daniel Orbach, Veronique Minard, Pierre Frange, MD, Danielle Canioni, MD, Isabelle Radford-Weiss, Vahid Asnafi, MD, PHD, jean-Laurent Casanova, Stephane Blanche, MD, Capucine Picard, MD, PhD, Frederic Rieux-Laucat, Frederic Davi, Nicole Brousse, M.D., Bertrand Nadel, PhD, Frank Ruemmele, Alain Fischer, MD/PhD
Journal: Blood
Blood (2012) 120 (21): 5092.
https://doi.org/10.1182/blood.V120.21.5092.5092
Published: 2012
Journal Articles

Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL

Sandrine Le Noir, Raouf Ben Abdelali, Marc Lelorch, Julie Bergeron, Stephanie Sungalee, Dominique Payet-Bornet, Patrick Villarèse, Arnaud Petit, Céline Callens, Ludovic Lhermitte, Laurence Baranger, Isabelle Radford-Weiss, Marie-José Grégoire, Hervé Dombret, Norbert Ifrah, Salvatore Spicuglia, Serge Romana, Jean Soulier, Bertrand Nadel, Elizabeth Macintyre, Vahid Asnafi
Journal: Blood
Blood (2012) 120 (16): 3298–3309.
https://doi.org/10.1182/blood-2012-04-425488
Published: 2012
Includes: Supplemental data
Journal Articles

Abnormalities of the Hematopoietic Stem Cell Compartment in Children After in Utero Exposure to AZT

Isabelle Andre-Schmutz, PhD, Liliane Dal Cortivo, Emmanuelle M. Six, PhD, Sophie Kaltenbach, Isabelle Radford-Weiss, Nicolas Cagnard, Fabienne Cocchiarella, Alexandra Benachi, Laurent Mandelbrot, Fulvio Mavilio, Marina Cavazzana-Calvo, MD, PhD, Stéphane Blanche, MD
Journal: Blood
Blood (2011) 118 (21): 1123.
https://doi.org/10.1182/blood.V118.21.1123.1123
Published: 2011
Journal Articles

Autologous stem cell transplantation as a first-line treatment strategy for chronic lymphocytic leukemia: a multicenter, randomized, controlled trial from the SFGM-TC and GFLLC

Clinical Trials & Observations
Laurent Sutton, Sylvie Chevret, Olivier Tournilhac, Marine Diviné, Véronique Leblond, Bernadette Corront, Stéphane Leprêtre, Houchingue Eghbali, Eric Van Den Neste, Mauricette Michallet, Frédéric Maloisel, Krimo Bouabdallah, Didier Decaudin, Christian Berthou, Pauline Brice, Hugo Gonzalez, Elise Chapiro, Isabelle Radford-Weiss, Nathalie Leporrier, Karim Maloum, Florence Nguyen-Khac, Frédéric Davi, Julie Lejeune, Hélène Merle-Béral, Michel Leporrier, for the Société Française de Greffe de Moelle et de Thérapie Cellulaire (SFGM-TC) and Groupe Français d'étude de la Leucémie Lymphoïde Chronique (GFLLC)
Journal: Blood
Blood (2011) 117 (23): 6109–6119.
https://doi.org/10.1182/blood-2010-11-317073
Published: 2011
Journal Articles

Specific Chromosomal IG Translocations Have Different Prognosis In Chronic Lymphocytic Leukemia

Florence Nguyen-Khac, CLaude Lesty, Elise Chapiro, Aurore Grelier, Isabelle Luquet, Isabelle Radford-Weiss, Sandra Fertferrer, Evelyne Callet-Bauchu, Christine Lefebvre, Eric Lippert, Christine Terré, Lucienne Michaux, Marie-Agnes Collonge-Rame, Carole Barin, Francine Mugneret, Pascaline Talmant, Sylvie Taviaux, Stephanie Struski, Virginie Eclache, Carine Gervais, Benoit Quilichini, Nathalie Gachard, Steven Richebourg, Nicole Dastugue, Catherine Settegrana, Frederic Davi, Karim Maloum, MD, PhD, Helene Merle-Beral
Journal: Blood
Blood (2010) 116 (21): 582.
https://doi.org/10.1182/blood.V116.21.582.582
Published: 2010
Journal Articles

Three Novel AML Cases Harboring the Semi-Cryptic t(7;21)(p22;q22) Translocation Expressing RUNX1-USP42 Fusion Transcripts Associated with Diploidy/Tetraploidy and/or 5q Alterations: a Probably Underestimated Combination

Eric Jeandidier, Carine Gervais, Isabelle Radford-Weiss, Catherine Gangneux, Valerie Rimelen, Georges Jung, Ines Harzallah, Bernard Drenou, Bruno Lioure, Laurent Mauvieux
Journal: Blood
Blood (2010) 116 (21): 2708.
https://doi.org/10.1182/blood.V116.21.2708.2708
Published: 2010
Journal Articles

Wide diversity of PAX5 alterations in B-ALL: a Groupe Francophone de Cytogénétique Hématologique study

Etienne Coyaud, Stephanie Struski, Nais Prade, Julien Familiades, Ruth Eichner, Cathy Quelen, Marina Bousquet, Francine Mugneret, Pascaline Talmant, Marie-Pierre Pages, Christine Lefebvre, Dominique Penther, Eric Lippert, Nathalie Nadal, Sylvie Taviaux, Bruce Poppe, Isabelle Luquet, Laurence Baranger, Virginie Eclache, Isabelle Radford, Carole Barin, Marie-Joëlle Mozziconacci, Marina Lafage-Pochitaloff, Hélène Antoine-Poirel, Christiane Charrin, Christine Perot, Christine Terre, Pierre Brousset, Nicole Dastugue, Cyril Broccardo
Journal: Blood
Blood (2010) 115 (15): 3089–3097.
https://doi.org/10.1182/blood-2009-07-234229
Published: 2010
Includes: Supplemental data
Journal Articles

Chromosomal Abnormalities in Transformed Ph-Negative Myeloproliferative Neoplasm Are Independent of the JAK2 and the TET2 Statuses.

Florence Nguyen-Khac, MD, PhD, Lucile Couronne, Virginie Eclache, Joris Andrieux, Eric Lippert, Olivier Kosmider, Francine Mugneret, Marie-Agnes Collonge-Rame, Dominique Penther, Marina Lafage, Nathalie Gachard, Nathalie Nadal, Marie-Joelle Mozziconacci, Nicole Dastugue, Chrystele Bilhou-Nabera, Stephanie Struski, Christine Cabrol, Isabelle Radford-Weiss, Claude Lesty, Olivier A Bernard
Journal: Blood
Blood (2009) 114 (22): 2900.
https://doi.org/10.1182/blood.V114.22.2900.2900
Published: 2009
Journal Articles

Prognostic and oncogenic relevance of TLX1/HOX11 expression level in T-ALLs

Clinical Trials & Observations
Julie Bergeron, Emmanuelle Clappier, Isabelle Radford, Agnès Buzyn, Corinne Millien, Gwendoline Soler, Paola Ballerini, Xavier Thomas, Jean Soulier, Hervé Dombret, Elizabeth A. Macintyre, Vahid Asnafi
Journal: Blood
Blood (2007) 110 (7): 2324–2330.
https://doi.org/10.1182/blood-2007-04-079988
Published: 2007
Includes: Supplemental data