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Shamyla Siddique
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Journal Articles

The UK Impact Transplant Trials Network: An Effective National Strategy to Accelerate the Delivery of Randomized Trials in Stem Cell Transplantation

Charles Craddock, David Marks, Victoria Potter, Wendy A Ingram, Rebecca Collings, Eleni Tholouli, Rachel Protheroe, Hugh Allen, Alex Ross, Dawn Farrar, Shamyla Siddique, Rebecca Bishop, Ronjon Chakraverty
Journal: Blood
Blood (2023) 142 (Supplement 1): 5097.
https://doi.org/10.1182/blood-2023-188490
Published: 2023
Journal Articles

Post-Transplant MRD Status and T Cell Chimerism Predict Outcomes in Patients Allografted for AML/MDS-a Prospective Analysis from the UK NCRI Figaro Trial

(Justin) Ching Ting Loke, Nicholas McCarthy, Aimee E Jackson, Shamyla Siddique, Andrea Hodgkinson, John Mason, Charles Crawley, Maria H Gilleece, Andy Peniket, Rachel Elizabeth Protheroe, Rahuman Salim, Eleni Tholouli, Keith Wilson, Georgia M. Andrew, Richard Dillon, Naeem Khan, Victoria Potter, Pramila Krishnamurthy, Charles Craddock, Sylvie D Freeman
Journal: Blood
Blood (2021) 138 (Supplement 1): 415.
https://doi.org/10.1182/blood-2021-149269
Published: 2021
Journal Articles

The Sequential Flamsa-Bu Conditioning Regimen Does Not Improve Outcome in Patients Allografted for High Risk Acute Myeloid and Myelodysplasia Irrespective of Pre-Transplant MRD Status: Results of the UK NCRI Figaro Trial

Charles Craddock, FRCP, FRCPath, Aimee E Jackson, MSc, Ram K Malladi, FRCPath, Maria H Gilleece, MD FRCPath, MB, BSc, FRCP, Andy Peniket, MD, Rahuman Salim, MRCP, FRCPath, Eleni Tholouli, MD PhD, Victoria Potter, MD PhD, Charles R Crawley, Rachel Elizabeth Protheroe, FRCPath,PhDMBBS,FRCP, Anne Parker, MD FRCP, BSc, FRCPath, Keith Wilson, FRCPath, MRCP, MBBS, Jiri Pavlu, MDMRCP,FRCPath, Sandeep Nagra, MBChB, Shamyla Siddique, BSc.(Hons.), MPhil, Andrea Hodgkinson, BSc(Hons),PhD, John Mason, Keith Wheatley, DPhil, Nigel H. Russell, MD, Sylvie D. Freeman, MBChB, DPhil
Journal: Blood
Blood (2019) 134 (Supplement_1): 2031.
https://doi.org/10.1182/blood-2019-125646
Published: 2019
Journal Articles

Vaccination with a DNA and MVA ‘Prime-Boost’ Regimen Induces Strong CD8 + T-Cell Responses Against the Immunodominant Minor Histocompatibility Antigen, HA-1: Results of a First-in-Man Phase I Clinical Trial

Charlotte F Inman, BVSc, PhD, Suzy A Eldershaw, BSc. (Hons.), PhD, Hayden Pearce, BSc. (Hons.), PhD, Ben E Abbotts, BSc. (Hons.), MSc., Mirjana Sirovica, BSc(Hons), MSc, Paul Ferguson, MD PhD MRCP, Donna L Walsh, Dip(HE), BSc., Jane Nunnick, BSC. (Hons.), MSc., Shamyla Siddique, BSc.(Hons.), MPhil, Paul Moss, MBBS, PhD FRCP, Ram K Malladi, FRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 1908.
https://doi.org/10.1182/blood.V130.Suppl_1.1908.1908
Published: 2017
Journal Articles

Combined Azacitidine and High Dose Lenalidomide Therapy Is Well Tolerated and Clinically Active in Patients Who Relapse after Allogeneic Stem Cell Transplantation for Actue Myeloid Leukemia: Results of the Uk Trials Acceleration Programme Viola Trial

Charles Craddock, Wendy Ingram, Daniel Slade, Andrea Hodgkinson, BSc(Hons),PhD, Francis J. Mussai, MA, MD DPhil, Carmela De Santo, Jamie Cavenagh, Michael Dennis, MDMRCP,FRCPath, Ram Malladi, MRCP, FRCPath, PhD, Shamyla Siddique, BSc.(Hons.), MPhil, Yap Christina, MSci, PhD CStat
Journal: Blood
Blood (2017) 130 (Supplement 1): 276.
https://doi.org/10.1182/blood.V130.Suppl_1.276.276
Published: 2017
Journal Articles

Vorinostat Does Not Improve Outcome in Patients with Acute Myeloid Leukemia and High Risk Myelodysplasia Treated with Azacitidine: Results of the UK Trials Acceleration Programme Ravva Trial

Charles Craddock, MD PhD, Aimee E Houlton, BSc, MSc, Paul Ferguson, MBChB MRCP PhD, Manoj Raghavan, Sonia Fox, Louise Dudley, BSc, MRes, Lynn Swun Quek, FRCPath, DPhil, MBBS, Jamie D. Cavenagh, Michael Dennis, FRCPath, Mary Frances McMullin, MD, Srinivas P Pillai, Richard Kelly, BSc, MD, Shamyla Siddique, Keith Wheatley, DPhil, Paresh Vyas, BM, DPhil, FRCP, FRCPath
Journal: Blood
Blood (2016) 128 (22): 1065.
https://doi.org/10.1182/blood.V128.22.1065.1065
Published: 2016
Journal Articles

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML)

Oliver C. Goodyear, Mike Dennis, Nadira Y. Jilani, Justin Loke, Shamyla Siddique, Gordon Ryan, Jane Nunnick, Rahela Khanum, Manoj Raghavan, Mark Cook, John A. Snowden, Mike Griffiths, Nigel Russell, John Yin, Charles Crawley, Gordon Cook, Paresh Vyas, Paul Moss, Ram Malladi, Charles F. Craddock
Journal: Blood
Blood (2012) 119 (14): 3361–3369.
https://doi.org/10.1182/blood-2011-09-377044
Published: 2012
Includes: Supplemental data
Journal Articles

Quantitation of Leukemic Stem Cell Populations Predicts Clinical Outcome in Acute Myeloid Leukaemia

Charles F. Craddock, MD PhD, Nicolas Goardon, PhD, Lynn Quek, MD, Sylvie Freeman, MD, PhD, Shamyla Siddique, Manoj Raghavan, Anna Schuh, PhD, David Grimwade, PhD, Robert K Hills, MA, MSc, DPhil, Cassandra Brookes, PhD, Michael Griffiths, PhD, James D. Cavenagh, MD, Ravindra Majeti, MD, PhD, Irving L. Weissman, MD, Alan K Burnett, MD, Paresh Vyas
Journal: Blood
Blood (2011) 118 (21): 638.
https://doi.org/10.1182/blood.V118.21.638.638
Published: 2011
Journal Articles

Azacitidine Induces Expansion of Regulatory T Cells and Tumour Specific CD8+ T Lymphocytes After Allogeneic Stem Cell Transplantation: A Strategy for Epigenetic Manipulation of a Graft-Versus-Leukemia Response

Mike Dennis, Oliver Goodyear, Justin Loke, Nadiria Jilani, Shamyla Siddique, Gordon Ryan, Rehela Khanum, John Snowden, Michael Griffiths, PhD, Nigel H. Russell, MD, John Yin, MD, Charles Crawley, MD, Gordon Cook, MD, PhD, Paresh Vyas, DPhil, FRCP, FRCPath, Paul AH Moss, MD PhD, Ram Malladi, Charles F. Craddock, BM, MRCP, MRCPath
Journal: Blood
Blood (2011) 118 (21): 324.
https://doi.org/10.1182/blood.V118.21.324.324
Published: 2011
Journal Articles

Induction of a CD8 + T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia

Clinical Trials & Observations
Oliver Goodyear, Angelo Agathanggelou, Igor Novitzky-Basso, Shamyla Siddique, Tina McSkeane, Gordon Ryan, Paresh Vyas, Jamie Cavenagh, Tanja Stankovic, Paul Moss, Charles Craddock
Journal: Blood
Blood (2010) 116 (11): 1908–1918.
https://doi.org/10.1182/blood-2009-11-249474
Published: 2010
Includes: Supplemental data
Journal Articles

5′ Azacitidine in Combination with Valproic Acid Induces Complete Remissions in Patients with Advanced Acute Myeloid Leukaemia but Does Not Eradicate Clonal Leukaemic Stem/Progenitor Cells.

Charles Craddock, BM, DPhil, FRCP, FRCPath, Nicolas Goardon, Mike Griffiths, James D. Cavenagh, MD, Shamyla Siddique, Paresh Vyas, BM, DPhil, FRCP, FRCPath
Journal: Blood
Blood (2008) 112 (11): 945.
https://doi.org/10.1182/blood.V112.11.945.945
Published: 2008
Journal Articles

Posttransplantation imatinib as a strategy to postpone the requirement for immunotherapy in patients undergoing reduced-intensity allografts for chronic myeloid leukemia

Brief Report
Eduardo Olavarria, Shamyla Siddique, Michael J. Griffiths, Sharon Avery, Jenny L. Byrne, Karen P. Piper, Anne L. Lennard, Lalit Pallan, Julie M. Arrazi, Jolanta B. Perz, Derville O'Shea, John M. Goldman, Jane F. Apperley, Charles F. Craddock
Journal: Blood
Blood (2007) 110 (13): 4614–4617.
https://doi.org/10.1182/blood-2007-04-082990
Published: 2007