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Journal Articles

Real-world effectiveness of gilteritinib beyond second-line therapy in relapsed/refractory FLT3-mutated acute myeloid leukemia: A european multicenter study of 171 patients

Free
Matteo Molica, Gema Miralles, Richard Dillon, Mario Annunziata, Faisal Basheer, Juan Miguel Bergua Burgues, Ferran Vall-Llovera Calmet, Victoria Campbell, Denis Cetin, Gaetano Cimino, Giulia Ciotti, andrea corbingi, LAURA DE FAZIO, Hasim Atakan Erol, Vincenzo Federico, Cristina Gil, Yasa Mutlu Gulu, Amaia Balerdi Malcorra, Sabrina Mariani, Maria Paola Martelli, Carla Mazzone, Antonino Mulè, Gerardo Musuraca, Anjum Khan, Mariana Norata, Jenny O'Nions, Fanny Palumbo, Cristina Papayannidis, Annalina Piccioni, Maria Teresa Olave Rubio, Jackeline Sanchez-Tovar, Istemi Serin, Alessandra Serrao, Omur Sevindik, Giuseppe Sucato, Marina Aurora Urbano, Calogero Vetro, Susana Vives, Marco Rossi, Pau Montesinos, Jad Othman, Salvatore Perrone
Journal: Blood
Blood (2025) 146 (Supplement 1): 1662.
https://doi.org/10.1182/blood-2025-1662
Published: 2025
Journal Articles

Excellent long-term outcomes after alemtuzumab-based hematopoietic cell transplantation (HCT) for severe aplastic anemia (SAA) and inherited bone marrow failure syndromes (IBMF): A 25-year British society of blood and marrow transplantation and cellular therapy (BSBMTCT) retrospective analysis of 1754 patients from the United Kingdom (UK)

Free
Austin Kulasekararaj, Kanchan Rao, Rachel Pearce, Julia Lee, Marie Wilson, Anjum Khan, Rachel Protheroe, Pramila Krishnamurthy, R.F. Wynn, Persis Amrolia, Victoria Potter
Journal: Blood
Blood (2025) 146 (Supplement 1): 984.
https://doi.org/10.1182/blood-2025-984
Published: 2025
Journal Articles

Addition of thiotepa to a busulphan based conditioning regimen does not improve survival in patients allografted for acute myeloid leukaemia and myelodysplasia: Results of the UK impact cosi trial

Free
Charles Craddock, Graham Mcllroy, Hannah Vincent, Gabrielle Smith, Sarah Johnson, Rebecca Collings, Rebecca Faville, Vitor Jesus, Victoria Potter, Eleni Tholouli, Rachel Protheroe, Andrew Clark, Keith Wilson, Alexander Martin, Charles Crawley, Amy Publicover, Andrew Peniket, Anjum Khan, Jiri Pavlu, Patrick Medd, Jenny Byrne, Ronjon Chakraverty, Wendy Ingram, Andrea Bacigalupo, Alessandro Rambaldi, Aimee Jackson, Sylvie Freeman
Journal: Blood
Blood (2025) 146 (Supplement 1): 110.
https://doi.org/10.1182/blood-2025-110
Published: 2025
Journal Articles

Peri-transplant ruxolitinib therapy significantly improves GVHD-free, relapse-free survival rates in transplantation for myelofibrosis

Free
Jack Illingworth, Jennifer Clay, Simon Bulley, Katja Kimberger, Chun Teh, Marina Karakantza, Suzanne Liebersbach, Janette Sampson, Gordon Cook, Anjum Khan
Journal: Blood
Blood (2025) 146 (Supplement 1): 4238.
https://doi.org/10.1182/blood-2025-4238
Published: 2025
Journal Articles

Real world outcomes in 355 patients with Acute Myeloid Leukemia arising from chronic myelomonocytic leukemia: A multinational retrospective study

Free
Laura Cicconi, Jad Othman, Alessandra Spagnoli, Enrico Attardi, Eleonora De Bellis, Pilar Lloret Madrid, Tamara Castaño, Juan Miguel Bergua Burgues, Arianna Savi, Ida Carmosino, Roberta Mazzarella, Armando Mena Duran, Mar Tormo, Susana Vives, Emília Cortesão, Fernanda Trigo, Mercedes Colorado, Lorenzo Algarra, Olga Salamero, José Antonio Pérez-Simón, Esther Perez, ANA Yurena Oliva Hernandez, Teresa Bernal Del Castillo, Pilar Martinez Sanchez, Claudia Lucia Scossa Melo, Cristina Gil, Marta Valero Núñez, Luis Felipe Casado Montero, Teresa Olave, Maria Vidriales Vicente, Carla Amigo, Irene Navarro Vicente, Cristian Escolano Escobar, Pilar Herrera Puente, Kenny Galvez, Rosalia Riaza Grau, Annalina Piccioni, Davide Facchinelli, Enrico Santinelli, Raffaele Palmieri, Giovanni Luzi, Monica Piedimonte, Sabrina Mariani, Luana Fianchi, Carmela Gurrieri, Ilaria Tanasi, Davide Lanzarotto, Fabio Guolo, Salvatore Perrone, Elisabetta Todisco, Anjum Khan, Victoria Campbell, Maria Teresa Voso, Daniela Cilloni, Adriano Venditti, Roberto Latagliata, Richard Dillon, Massimo Breccia, Luca Maurillo, Susanna Fenu, Alessandro Pulsoni, Pau Montesinos
Journal: Blood
Blood (2025) 146 (Supplement 1): 3437.
https://doi.org/10.1182/blood-2025-3437
Published: 2025
Journal Articles

Effectiveness and safety of CPX-351 in younger patients <60 years with newly diagnosed secondary Acute Myeloid Leukemia: Pooled analysis of US (V-RULES) and UK (CREST-UK) real-world studies

Free
Thomas LeBlanc, Amir Ali, Victoria Campbell, Onyee Chan, Thomas Coats, Doria Cole, Daniel Cuadras, Nicholas Cunningham, Yngvar Floisand, Gillian Flynn, Jesus Gonzalez-Lugo, Katherine Hodgson, Anjum Khan, Kristin Koenig, Catherine Lai, Alex Legg, Mimi Lo, Amanda Lopez, Mark Lynam, Jamie Maddox, Sateesh Nagumantry, Matthew Newman, Jenny O'Nions, Saemi Park, Montse Pedrós, Giuseppe Piccoli, Melisa Stricherz, David Taussig, Charlotte Wagner, Eunice Wang, Richard Whitmill, George Yaghmour, Rui Zhao, Priyanka Mehta
Journal: Blood
Blood (2025) 146 (Supplement 1): 5215.
https://doi.org/10.1182/blood-2025-5215
Published: 2025
Journal Articles

Prospective Cohort Study of Non-COVID Infection in Patients with AML/MDS Undergoing Treatment: Implications for Practice

Free
Justin CT Loke, Charlotte Gaskell, Emily Yafai, Sonia Fox, Catherine Thomas, Louise Hopkins, Rebecca Boucher, Rebecca Collings, Steve Knapper, Anjum Khan, Jane Nunnick, Katie Randall, Jenny O'Nions, Tom Rider, Arpad Toth, Mary Frances McMullin, Sally Moore, Victoria Drew, Farooq Ahmad Wandroo, Pratap Neelakantan, Pramila Krishnamurthy, Charles Craddock, Sylvia Rofael, Vinit Upsani, David M Lowe, Simon J Stanworth
Journal: Blood
Blood (2024) 144 (Supplement 1): 120.
https://doi.org/10.1182/blood-2024-200732
Published: 2024
Journal Articles

Molecular MRD is strongly prognostic in patients with NPM1 -mutated AML receiving venetoclax-based nonintensive therapy

Free
Clinical Trials & Observations Brief Report
Jad Othman, Ing S. Tiong, Jenny O'Nions, Mike Dennis, Katya Mokretar, Adam Ivey, Michael Austin, Anne-Louise Latif, Mariam Amer, Wei Yee Chan, Charles Crawley, Francesca Crolla, Joe Cross, Ray Dang, Johnathon Elliot, Chun Y. Fong, Sofia Galli, Paolo Gallipoli, Francesca Hogan, Pallavi Kalkur, Anjum Khan, Pramila Krishnamurthy, John Laurie, Sun Loo, Scott Marshall, Priyanka Mehta, Vidhya Murthy, Sateesh Nagumantry, Srinivas Pillai, Nicola Potter, Rob Sellar, Tom Taylor, Rui Zhao, Nigel H. Russell, Andrew H. Wei, Richard Dillon
Journal: Blood
Blood (2024) 143 (4): 336–341.
https://doi.org/10.1182/blood.2023021579
Published: 2024
Includes: Supplemental data
Journal Articles

Opsoclonus-Myoclonus Syndrome and Acquired Von Willebrand Syndrome As Manifestations of Graft-Versus-Host Disease

Free
Amany Ihab Mohamed, Simon Bulley, Julie Tarrant, Katja Kimberger, Hussnain Javaid, Suzanne Liebersbach, Anjum Khan
Journal: Blood
Blood (2023) 142 (Supplement 1): 7034.
https://doi.org/10.1182/blood-2023-187798
Published: 2023
Journal Articles

Molecular MRD Assessment Is Strongly Prognostic in Patients with NPM1 Mutated AML Receiving Venetoclax Based Non-Intensive Therapy

Free
Jad Othman, Ing S Tiong, Katya Mokretar, Adam Ivey, Michael James Austin, Anne-Louise Latif, Charles Crawley, Mariam Amer, Francesca Crolla, Joe W Cross, Raymond Dang, Chun Yew Fong, Sofia Galli, Paolo Gallipoli, Francesca L Hogan, Pallavi Kalkur, Anjum Khan, Pramila Krishnamurthy, John Laurie, Scott R. Marshall, Vidhya Murthy, Sateesh K. Nagumantry, Srinivas Pillai, Nicola Potter, Tom Taylor, Rui Zhao, Andrew H Wei, Richard Dillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 2033–2035.
https://doi.org/10.1182/blood-2022-159467
Published: 2022
Journal Articles

CREST-UK: CPX-351 Real-World Effectiveness and Safety Study for the Treatment of Newly Diagnosed Therapy-Related AML and AML with Myelodysplasia-Related Changes in the UK

Free
Priyanka Mehta, Anjum Khan, Jamie Maddox, Yngvar Floisand, Richard Whitmill, Daniel Cuadras, Montse Pedros, Saemi Park, Greg Medalla, Alex Legg, Victoria Louise Campbell
Journal: Blood
Blood (2022) 140 (Supplement 1): 6152–6154.
https://doi.org/10.1182/blood-2022-159496
Published: 2022
Journal Articles

High Molecular Response Rate and Overall Survival with FLT3 Inhibitors As MRD-Guided Salvage Treatment for Molecular Failure in AML

Free
Jad Othman, Nicola Potter, Katya Mokretar, David Taussig, Anjum Khan, Pramila Krishnamurthy, Anne-Louise Latif, Paul Cahalin, James Aries, Mariam Amer, Edward Belsham, Eibhlin Conneally, Charles Craddock, Dominic Culligan, Mike Dennis, Caroline Duncan, Caroline Furness, Paraskevi Gkreka, Katherine Hodgson, Wendy Ingram, Andrew King, Panagiotis Kottaridis, Mary Frances McMullin, Unmesh Mohite, Loretta Ngu, Katharine Patrick, Tom Rider, Wing Roberts, Marianne Tang Severinsen, Neill Storrar, Tom Taylor, Nigel H. Russell, Richard Dillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 2002–2004.
https://doi.org/10.1182/blood-2022-159503
Published: 2022
Journal Articles

Venetoclax-Based Non-Intensive Combinations Successfully Salvage Molecular Relapse of Acute Myeloid Leukemia and Are an Important Bridge to Cellular Therapy in Relapsed/Refractory Disease - Real-World Data from a UK-Wide Programme

Free
Henry Wood, Christianne Bourlon, Austin Kulasekararaj, Albert Borg, Jiri Pavlu, Patrick Elder, David C Taussig, Scott Veitch, Steven Knapper, Jad Othman, Richard Dillon, James Aries, Emily Mitchell, Faisal Basheer, Steven Leak, Vidhya Murthy, Joe W Cross, Priyanka Mehta, Manish Jain, Anjum Khan, Ho Lam, Sarah Leong, Jenny O'Nions, Charles Craddock, Victoria Potter, Mhairi Copland, Pramila Krishnamurthy
Journal: Blood
Blood (2022) 140 (Supplement 1): 9016–9018.
https://doi.org/10.1182/blood-2022-167097
Published: 2022
Journal Articles

Venetoclax with Azacitidine or Low Dose Cytarabine As an Alternative to Intensive Chemotherapy in Fit Adults during the COVID19 Pandemic: Real World Data from the UK National Health Service

Free
Jad Othman, Mariam Amer, Ruebina Amofa, Laura Anderson, Michael J Austin, Alex Bashford, Edward Belsham, Jesca Boot, Victoria Louise Campbell, Thomas Coats, Angela Collins, Charles Crawley, Francesca Crolla, Joe W Cross, Chris Dalley, Raymond Dang, Mike Dennis, Saniya Dhawan, Johnathon Elliott, Sofia Galli, Paolo Gallipoli, Katherine Hodgson, Manish Jain, Pallavi Kalkur, Vana Katsomitrou, Anjum Khan, Asim Khwaja, Pramila Krishnamurthy, Annie Latif, John Laurie, Michael Lim, Eleana Loizou, Justin Loke, Deepak Mannari, Cara Manson, Scott R. Marshall, Behnaz Mobashwera, Vidhya Murthy, Odong Ochaya, Shahzad Orthi, Renuka Palanicawandar, Srinivas Pillai, Dominika Radzova, Adam Rye, Jamie Saunders, Matthew Smith, David Taussig, Tom Taylor, Richard Whitmill, Rui Zhao, Sylvie D Freeman, Charles Craddock, Richard Dillon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2321.
https://doi.org/10.1182/blood-2021-149685
Published: 2021
Journal Articles

Gilteritinib for Relapsed Acute Myeloid Leukaemia with FLT3 Mutation during the COVID-19 Pandemic: Real World Experience from the UK National Health Service

Free
Jad Othman, Usman Afzal, Ruebina Amofa, Michael J Austin, Alex Bashford, Edward Belsham, Jennifer Byrne, Thomas Coats, Raymond Dang, Mike Dennis, Saniya Dhawan, Johnathon Elliot, Sebastian Francis, Paolo Gallipoli, Katherine Hodgson, Charlotte Kallmeyer, Manish Jain, Vana Katsomitrou, Anjum Khan, Asim Khwaja, Seye Kolade, Pramila Krishnamurthy, Annie Latif, John Laurie, Michael Lim, (Justin) Ching Ting Loke, Cara Manson, Scott R. Marshall, Behnaz Mobashwera, Sreetharan Munisamy, Duncan Murray, Vidhya Murthy, Renuka Palanicawandar, Jamie Saunders, Matthew Smith, Katherine Smith, Alex Sternberg, David Taussig, Tom Taylor, Sylvie D Freeman, Charles Craddock, Richard Dillon
Journal: Blood
Blood (2021) 138 (Supplement 1): 1254.
https://doi.org/10.1182/blood-2021-150169
Published: 2021
Journal Articles

Low Incidence of COVID-19 Infection in Patients with Acute Myeloid Leukemia Undergoing Reduced Intensity/Venetoclax Based Treatment: Initial Results of the PACE Prospective Clinical Study from the UK Trials Acceleration Program

Free
(Justin) Ching Ting Loke, Charlotte Gaskell, Sonia Fox, Rachel Fletcher, Catherine Thomas, Louise Hopkins, Anita Kumari, Rebecca H. Boucher, Jane Nunnick, Steve Knapper, Arpad Toth, Jennifer Byrne, Jenny O'Nions, Anjum Khan, Rui Zhao, Arvind Pillai, Eleni Tholouli, Moez Dungarwalla, Katie Randall, Richard Dillon, Duncan Murray, Dominic Culligan, Mary Frances McMullin, Yuen Ling Tracey Chan, Victoria Drew, Vidhya Murthy, Pramila Krishnamurthy, Pratap Neelakantan, Tom Rider, Farooq A Wandroo, Mark Rafferty, Ya-Wen Huang, Sally Moore, Priyanka Mehta, David G Partridge, Charles Craddock, David Lowe, Simon J. Stanworth
Journal: Blood
Blood (2021) 138 (Supplement 1): 1942.
https://doi.org/10.1182/blood-2021-146061
Published: 2021
Journal Articles

Molecular MRD status and outcome after transplantation in NPM1 -mutated AML

Free
Clinical Trials & Observations
Richard Dillon, Robert Hills, Sylvie Freeman, Nicola Potter, Jelena Jovanovic, Adam Ivey, Anju Shankar Kanda, Manohursingh Runglall, Nicola Foot, Mikel Valganon, Asim Khwaja, Jamie Cavenagh, Matthew Smith, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Steven Knapper, Harpreet Kaur, David Taussig, Priyanka Mehta, Kavita Raj, Igor Novitzky-Basso, Emmanouil Nikolousis, Robert Danby, Pramila Krishnamurthy, Kate Hill, Damian Finnegan, Samah Alimam, Erin Hurst, Peter Johnson, Anjum Khan, Rahuman Salim, Charles Craddock, Ruth Spearing, Amanda Gilkes, Rosemary Gale, Alan Burnett, Nigel H. Russell, David Grimwade
Journal: Blood
Blood (2020) 135 (9): 680–688.
https://doi.org/10.1182/blood.2019002959
Published: 2020
Includes: Supplemental data