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Journal Articles

Tolerance of Whole Genome Duplication in Megakaryocytes, and Consequences for Their Genome Integrity

Antonio Rodriguez-Romera, Rong Li, Nah-Young Shin, Sally-Ann Clark, Assunta Adamo, Affaf Aliouat, Abdullah Khan, Aude-Anais Olijnik, Jill Brown, Lucia Sommerova, Natalie Jooss, Akiko Shimamura, Xin Lu, Guanlin Wang, Stefan N. Constantinescu, Ketan Patel, Adam J Mead, Alan B. Cantor, Bethan Psaila

Blood (2024) 144 (Supplement 1): 421.

https://doi.org/10.1182/blood-2024-203123

Published: 2024

Journal Articles

Integrative Analysis of the Genomic and Transcriptomic Landscape of Relapsed/Refractory Multiple Myeloma Patients Treated With Venetoclax in Combination With Bortezomib and Dexamethasone: Biomarker Analyses From the Phase 3 BELLINI Study

Michael E. O'Dwyer, MD, Andrew Spencer, MBBS, FRACP, FRCPA, DM, Shaji K. Kumar, MD, Rakesh Popat, Philippe Moreau, MD, Monique Dail, PhD, Muhammad Jalaluddin, PhD, Xiaoqing Yang, PhD, Xin Lu, Zheng Zha, Fengjiao Dunbar, PhD, Deeksha Vishwamitra, PhD, Christine Mantis, PhD, Amal Melhem-Bertrandt, MD, Jeremy A. Ross, Simon J Harrison, MBBS MRCP (UK) PhDFRCPath (UK) FRACP

Blood (2020) 136 (Supplement 1): 40–41.

https://doi.org/10.1182/blood-2020-134710

Published: 2020

Journal Articles

Ex Vivo Drug Sensitivity and Functional Genomics Platform Identifies Novel Combinations Targeting Intrinsic and Extrinsic Apoptotic Signaling Pathways in Multiple Myeloma

Ariosto Siqueira Silva, PhD, Rafael Renatino-Canevarolo, PhD, Mark B. Meads, PhD, Maria D Coelho Siqueira Silva, MSc, Praneeth Reddy Sudalagunta, PhD, Christopher Cubitt, Gabriel De Avila, BS, Raghunandan Reddy Alugubelli, Amit Kulkarni, PhD, Melissa Mitchell, Hongyue Dai, Qi Zhang, PhD, Oliver Hampton, Xin Lu, Dimple A. Modi, PhD, Monica Motwani, PhD, Jason Harb, PhD, Jeremy A. Ross, Kenneth H. Shain, MD PhD

Blood (2020) 136 (Supplement 1): 49–50.

https://doi.org/10.1182/blood-2020-134924

Published: 2020

Journal Articles

Selective Targeting BET Family Bdii Bromodomain with Abbv-744 and BCL-2 with Venetoclax (ABT-199) Is Synergistic in Primary Acute Myeloid Leukemia Models

Tianyu Cai, PhD, Vinitha Mary Kuruvilla, MSc, Xiaoyu Lin, Tamar Uziel, PhD, Xin Lu, Lu Zhang, Xiaoli Huang, Qi Zhang, PhD, Antonio Cavazos, Lina Han, PhD, Yu Shen, Marina Y Konopleva, MD PhD

Blood (2019) 134 (Supplement_1): 1369.

https://doi.org/10.1182/blood-2019-128618

Published: 2019

Journal Articles

Targeting the Second Bromodomain (BDII) of BET Family with Abbv-744 Results in Robust Anti-Leukemia Activity in AML Models with Excellent In Vivo Tolerability

Tianyu Cai, PhD, Vinitha Mary Kuruvilla, Tamar Uziel, PhD, Qi Zhang, PhD, Lina Han, PhD, Antonio Cavazos, MSc, Yu Shen, Marina Y. Konopleva, MD PhD, Xiaoyu Lin, Xin Lu, Lu Zhang

Blood (2018) 132 (Supplement 1): 1439.

https://doi.org/10.1182/blood-2018-99-116912

Published: 2018

Journal Articles

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres

Jianwei Wang, Xin Lu, Vadim Sakk, Christoph A. Klein, Karl Lenhard Rudolph

Blood (2014) 124 (22): 3237–3240.

https://doi.org/10.1182/blood-2014-04-568055

Published: 2014

Includes: Supplemental data

Journal Articles

Whole-Genome Sequencing of a Monozygotic Twin Pair Reveals Functional Cooperative Mutations of SETD2 in Acute Leukemia

Blood (2012) 120 (21): 781.

https://doi.org/10.1182/blood.V120.21.781.781

Published: 2012

Journal Articles

Shear Stress Directly Regulates Platelet αIIbβ3 Signaling.

Shuju Feng, PhD, Xin Lu, BS, Julio C. Resendiz, Michael H. Kroll, MD

Blood (2005) 106 (11): 3570.

https://doi.org/10.1182/blood.V106.11.3570.3570

Published: 2005

Journal Articles

Filamin Binding to Glycoprotein Ibα Signals Talin-Directed α IIbβ 3 Activation.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD

Blood (2005) 106 (11): 383.

https://doi.org/10.1182/blood.V106.11.383.383

Published: 2005

Journal Articles

A Novel Method of Isolation of Mesenchymal Stem Cells from Human Umbilical Cord Tisssues.

Lulu Lu, MD, Yong-jun Liu, MD, Zhen-shu Xu, MD, Cun-gang Fan, MD, Han Wang, MD, Wei Gong, MD, Zhi-bo Han, MD, Yong-xin Lu, MD, Delong Liu, MD, PhD, Zhi-zhe Chen, MD, Zhong-chao Han, MD

Blood (2005) 106 (11): 4306.

https://doi.org/10.1182/blood.V106.11.4306.4306

Published: 2005

Journal Articles

Posttranslational modifications of p27 kip1 determine its binding specificity to different cyclins and cyclin-dependent kinases in vivo

Wenqing Zhang, Daniele Bergamaschi, Boquan Jin, Xin Lu

Blood (2005) 105 (9): 3691–3698.

https://doi.org/10.1182/blood-2003-07-2558

Published: 2005

Journal Articles

Filamin A Binding Stabilizes Nascent Glycoprotein Ibα Trafficking and Thereby Enhances Its Surface Expression.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD

Blood (2004) 104 (11): 3656.

https://doi.org/10.1182/blood.V104.11.3656.3656

Published: 2004

Journal Articles

A Contractile Cytoskeletal Tether Modulates Signaling between Glycoprotein Ibα and αIIbβ3.

Shuju Feng, PhD, Xin Lu, BS, Michael H. Kroll, MD

Blood (2004) 104 (11): 1554.

https://doi.org/10.1182/blood.V104.11.1554.1554

Published: 2004

Journal Articles

Filamin A binding to the cytoplasmic tail of glycoprotein Ibα regulates von Willebrand factor–induced platelet activation

Shuju Feng, Julio C. Reséndiz, Xin Lu, Michael H. Kroll

Blood (2003) 102 (6): 2122–2129.

https://doi.org/10.1182/blood-2002-12-3805

Published: 2003

NARROW

Tolerance of Whole Genome Duplication in Megakaryocytes, and Consequences for Their Genome Integrity

Integrative Analysis of the Genomic and Transcriptomic Landscape of Relapsed/Refractory Multiple Myeloma Patients Treated With Venetoclax in Combination With Bortezomib and Dexamethasone: Biomarker Analyses From the Phase 3 BELLINI Study

Ex Vivo Drug Sensitivity and Functional Genomics Platform Identifies Novel Combinations Targeting Intrinsic and Extrinsic Apoptotic Signaling Pathways in Multiple Myeloma

Selective Targeting BET Family Bdii Bromodomain with Abbv-744 and BCL-2 with Venetoclax (ABT-199) Is Synergistic in Primary Acute Myeloid Leukemia Models

Targeting the Second Bromodomain (BDII) of BET Family with Abbv-744 Results in Robust Anti-Leukemia Activity in AML Models with Excellent In Vivo Tolerability

Senescence and apoptosis block hematopoietic activation of quiescent hematopoietic stem cells with short telomeres

Whole-Genome Sequencing of a Monozygotic Twin Pair Reveals Functional Cooperative Mutations of SETD2 in Acute Leukemia

Shear Stress Directly Regulates Platelet αIIbβ3 Signaling.

Filamin Binding to Glycoprotein Ibα Signals Talin-Directed α IIbβ 3 Activation.

A Novel Method of Isolation of Mesenchymal Stem Cells from Human Umbilical Cord Tisssues.

Posttranslational modifications of p27 kip1 determine its binding specificity to different cyclins and cyclin-dependent kinases in vivo

Filamin A Binding Stabilizes Nascent Glycoprotein Ibα Trafficking and Thereby Enhances Its Surface Expression.

A Contractile Cytoskeletal Tether Modulates Signaling between Glycoprotein Ibα and αIIbβ3.

Filamin A binding to the cytoplasmic tail of glycoprotein Ibα regulates von Willebrand factor–induced platelet activation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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