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Lisa Polin
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Journal Articles

Loss of Cystathionine-β-Synthase Activity Results in Increased Oxidative Phosphorylation and Cytarabine Resistance in Myeloid Leukemia Associated with Down Syndrome

Jenna Thibodeau, Jianlei Zhao, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Kathryn H White, Maik Hüttemann, Tasnim Arroum, Lucynda Pham, Austin C. Boucher, John D. Crispino, Jeffrey W. Taub, Yubin Ge
Journal: Blood
Blood (2024) 144 (Supplement 1): 1376.
https://doi.org/10.1182/blood-2024-203961
Published: 2024
Journal Articles

Combined Use of Ziftomenib and Selinexor Is Effective in NPM1 Mutant Acute Myeloid Leukemia

Sandhya Dhiman, Md. Hafiz Uddin, Vikram Dhillon, Jeff Justin Aguilar, Amro Aboukameel, Husain Khan, Sahar Bannoura, Jay Yang, Gregory Dyson, Steven Buck, Asfar Azmi, Lisa Polin, Francis Burrows, Linda Kessler, Jaroslaw Maciejewski, Suresh Kumar Balasubramanian
Journal: Blood
Blood (2024) 144 (Supplement 1): 2768.
https://doi.org/10.1182/blood-2024-206075
Published: 2024
Journal Articles

Old Meets New: Hydroxyurea Synergistically Enhances the Antileukemic Activity of Gilteritinibagainst FLT3-ITD AML

Nibal Eid, Jianlei Zhao, Jenna Thibodeau, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H Dzinic, Kathryn H White, Steven Buck, Jeffrey W. Taub, Yubin Ge
Journal: Blood
Blood (2024) 144 (Supplement 1): 5805.
https://doi.org/10.1182/blood-2024-207855
Published: 2024
Journal Articles

The Clinical Menin Inhibitor Ziftomenib and the Nuclear Export Inhibitor Selinexor Synergistically Inhibit the Growth of MLL-r AML

Md. Hafiz Uddin, Amro Aboukameel, Sharif hasan Siddiqui, Husain Khan, Sahar Bannoura, Abhinav Deol, Jay Yang, Gregory Dyson, Asfar Azmi, Lisa Polin, Jaroslaw P. Maciejewski, Suresh Kumar Balasubramanian
Journal: Blood
Blood (2023) 142 (Supplement 1): 4168.
https://doi.org/10.1182/blood-2023-190638
Published: 2023
Journal Articles

A Novel Isoflavone, ME-344, Enhances Venetoclax Antileukemic Activity Against AML Via Suppression of Oxidative Phosphorylation and Purine Biosynthesis

Katie Hege Hurrish, Yongwei Su, Sandra Wiley, Zhanjun Hou, Jenna Carter, Hasini Kalpage, Maik Hüttemann, Holly Edwards, Lisa Polin, Jing Li, Jay Yang, Larry Matherly, Jeffrey W. Taub, Yubin Ge
Journal: Blood
Blood (2021) 138 (Supplement 1): 2238.
https://doi.org/10.1182/blood-2021-147004
Published: 2021
Journal Articles

The Combination of CUDC-907 and Gilteritinib Shows Promising Antileukemic Activity in Vitro and In Vivo in Preclinical Models of FLT3-ITD AML

Tristan Knight, MD, Xinan Qiao, BS, Jun Ma, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Kathryn White, Hai Lin, MD, Yue Wang, Jeffrey W. Taub, MD, Yubin Ge, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1262.
https://doi.org/10.1182/blood-2019-123793
Published: 2019
Journal Articles

Venetoclax Synergistically Enhances the Antileukemic Activity of Imipridone ONC213, a Novel Imipridone ONC201 Analog, in Acute Myeloid Leukemia

Yongwei Su, Xinyu Li, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Katie Hege, Yu Fukuda, John D. Schuetz, PhD, Joshua E. Allen, PhD, Martin Stogniew, Varun Vijay Prabhu, BPharm, MS, PhD, Jeffrey W. Taub, MD, Hai Lin, MD, Yubin Ge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3936.
https://doi.org/10.1182/blood-2018-99-116997
Published: 2018
Journal Articles

Voruciclib, an Oral, Selective CDK9 Inhibitor, Enhances Cell Death Induced By the Bcl-2 Selective Inhibitor Venetoclax in Acute Myeloid Leukemia

Daniel A Luedtke, BS, Yongwei Su, Holly Edwards, BS, Lisa Polin, PhD, Juiwanna Kushner, Sijana H Dzinic, PhD, Hai Lin, MD, Jeffrey W. Taub, MD, Yubin Ge, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1361.
https://doi.org/10.1182/blood-2018-99-118372
Published: 2018
Journal Articles

Synergistic Antileukemic Interactions Between Valproic Acid and Cytarabine: A Potential Means to Improve the Treatment of Pediatric Acute Myeloid Leukemia.

Chengzhi Xie, Holly Edwards, Lisa Polin, Hui Zhou, Xuanlin Wang, Song Yang, Salvatore B LoGrasso, Steven Buck, Mark Stout, Jeffrey Rubnitz, MD, PhD, Larry Matherly, PhD, Jeffrey Taub, MD, Qun Yu, Yubin Ge, PhD
Journal: Blood
Blood (2009) 114 (22): 2084.
https://doi.org/10.1182/blood.V114.22.2084.2084
Published: 2009
Journal Articles

Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog

Yuxiang Zhang, Marcia I. Dawson, Yangmin Ning, Lisa Polin, Ralph E. Parchment, Thomas Corbett, Anwar N. Mohamed, Kai-Chia Feng, Lulu Farhana, Arun K. Rishi, Donna Hogge, Mark Leid, Valerie J. Peterson, Xiao-kun Zhang, Ramzi Mohammad, Jing-Song Lu, Cheryl Willman, Eric VanBuren, Sandra Biggar, Mark Edelstein, David Eilender, Joseph A. Fontana
Journal: Blood
Blood (2003) 102 (10): 3743–3752.
https://doi.org/10.1182/blood-2003-01-0108
Published: 2003