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Journal Articles

Redox Redux: Nrf2 Mediates Resistance to Ferroptosis and Apoptosis in High Grade B-Cell Lymphoma

Meiying Yang, Jonathan S Rink, Adam Yuh Lin, Shuo Yang, Colby Shad Thaxton, Leo I. Gordon
Journal: Blood
Blood (2024) 144 (Supplement 1): 5832.
https://doi.org/10.1182/blood-2024-210592
Published: 2024
Journal Articles

Receptor Targeted Delivery of the p38γ Inhibitor PIK-75 By Organic-Core Templated Lipid Nanoparticles in Cutaneous T Cell Lymphoma

Jonathan Scott Rink, Stephen E. Henrich, Alexandra Moxley, Xu Hannah Zhang, Xiwei Wu, SonBinh Nguyen, Christiane Querfeld, David A. Horne, Steve T. Rosen, Leo I. Gordon, Colby Shad Thaxton, Adam Yuh Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 4934–4935.
https://doi.org/10.1182/blood-2022-158864
Published: 2022
Journal Articles

Synthetic Lipid Nanoparticles Actively Target Acute Myeloid Leukemia (AML) Cells and Induce Ferroptosis through Decreased Expression of Glutathione Peroxidase 4

Adam Yuh Lin, Jonathan Scott Rink, Eva Yang, Sara Small, Fransheska Serrano, Yasmin Abaza, Jessica K. Altman, Leonidas C. Platanias, Colby Shad Thaxton, Leo I. Gordon
Journal: Blood
Blood (2022) 140 (Supplement 1): 5967–5968.
https://doi.org/10.1182/blood-2022-168154
Published: 2022
Journal Articles

Investigations of Redox Resistance in Aggressive Lymphomas with Cholesterol Modulating Lipid Nanoparticles

Meiying Yang, Jonathan Scott Rink, Shuo Yang, Eva Yang, Kaylin Marie McMahon, Colby Shad Thaxton, Leo I. Gordon, Adam Yuh Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 5993–5994.
https://doi.org/10.1182/blood-2022-168394
Published: 2022
Journal Articles

In Situ Vaccination with Combination of Class B and Class C Toll-like Receptor 9 Agonist CpG Immune Adjuvant Nanoparticles to Induce a Systemic Anti-Lymphoma Response

Adam Yuh Lin, Jonathan Scott Rink, Colby Shad Thaxton, Leo I. Gordon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2265.
https://doi.org/10.1182/blood-2021-147104
Published: 2021
Journal Articles

Bio-Inspired Functional Lipoprotein-like Nanoparticles (Flip-NPs) Cause Cholesterol Starvation and Ferroptosis in B-Cell Lymphomas: Studies in Cell Lines, Xenograft Models and Primary Patient Samples

Jonathan Rink, PhD, Adam Yuh Lin, MD PhD, Shuo Yang, PhD, Amir Behdad, MD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2857.
https://doi.org/10.1182/blood-2019-127805
Published: 2019
Journal Articles

Engineering CpG Deoxynucleotide-Conjugated Gold Nanoparticles for Enhanced Anti-Lymphoma Effects in an Immune Competent Lymphoma Model

Adam Yuh Lin, MD PhD, Jonathan Rink, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1577.
https://doi.org/10.1182/blood-2019-125308
Published: 2019
Journal Articles

Inhibition of Pro-Survival Pathways in DLBCL Cells By Functional Lipoprotein-like Nanoparticles

Jonathan Rink, PhD, Shuo Yang, PhD, Osman Cen, PhD, Reem Karmali, MD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1668.
https://doi.org/10.1182/blood-2018-99-119122
Published: 2018
Journal Articles

Rational Targeting of Cellular Cholesterol in Diffuse Large B-Cell Lymphoma (DLBCL) Enabled By Functional Lipoprotein Nanoparticles and the B Cell Receptor Inhibitor Ibrutinib: A Therapeutic Strategy Dependent on Cell of Origin (COO)

Jonathan Rink, PhD, Osman Cen, PhD, Kaylin Marie McMahon, PhD, Sol Misener, BS, Shuo Yang, PhD, Colby Shad Thaxton, MD PhD, Leo I. Gordon, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 576.
https://doi.org/10.1182/blood.V130.Suppl_1.576.576
Published: 2017
Journal Articles

High Density Lipoprotein-like Nanoparticles Synergize with Akt and Btk Inhibitors to Induce Cell Death in Diffuse Large B Cell Lymphomas

Jonathan Scott Rink, PhD, Sol Misener, Osman Cen, PhD, Shuo Yang, Leo I. Gordon, MD, Colby Shad Thaxton, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 3022.
https://doi.org/10.1182/blood.V128.22.3022.3022
Published: 2016
Journal Articles

Synthetic High-Density Lipoprotein-like Nanoparticles (HDL NP) Cause Apoptosis and Enhance Killing By B-Cell Receptor and BCL-2 Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Kaylin Marie McMahon, Cristina Scielzo, Lydia Scarfo, Pamela Ranghetti, Shuo Yang, Leo I. Gordon, MD, Frank Giles, MDMB, Colby Shad Thaxton, MD PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2949.
https://doi.org/10.1182/blood.V126.23.2949.2949
Published: 2015
Journal Articles

Scavenger Receptor Type B1 Is Essential for High Density Lipoprotein Nanoparticle Induced B-Cell Lymphoma Cell Death

Jonathan Scott Rink, PhD, Shuo Yang, Osman Cen, Fei Ying, Young Kwang Chae, MD MPH, Denise Scholtens, Jonathan Moreira, MD, Amy Chadburn, MD, Leo I. Gordon, MD, Colby Shad Thaxton
Journal: Blood
Blood (2015) 126 (23): 2756.
https://doi.org/10.1182/blood.V126.23.2756.2756
Published: 2015