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Journal Articles

Outcomes of Venetoclax Retreatment after MRD-Guided Venetoclax +/- Ibrutinib: Results of the Improve Study

Elisa Albi, Lydia Scarfo, Silvia Heltai, Eloise Scarano, Luana Schiattone, Lucia Farina, Riccardo Moia, Marina Deodato, Andrea Ferrario, Marina Motta, Alessandro Noto, Rosaria Sancetta, Marta Coscia, Paolo Rivela, Luca Laurenti, Marzia Varettoni, Eleonora Perotta, Antonella Capasso, Pamela Ranghetti, Francesca Martini, Emanuela Sant'Antonio, Catalina Combi, Maria Colia, Paolo Ghia
Journal: Blood
Blood (2023) 142 (Supplement 1): 6521.
https://doi.org/10.1182/blood-2023-174603
Published: 2023
Journal Articles

Minimal residual disease–driven treatment intensification with sequential addition of ibrutinib to venetoclax in R/R CLL

Clinical Trials & Observations
Lydia Scarfò, Silvia Heltai, Elisa Albi, Eloise Scarano, Luana Schiattone, Lucia Farina, Riccardo Moia, Marina Deodato, Andrea Ferrario, Marina Motta, Gianluigi Reda, Rosaria Sancetta, Marta Coscia, Paolo Rivela, Luca Laurenti, Marzia Varettoni, Eleonora Perotta, Antonella Capasso, Pamela Ranghetti, Maria Colia, Paolo Ghia
Journal: Blood
Blood (2022) 140 (22): 2348–2357.
https://doi.org/10.1182/blood.2022016901
Published: 2022
Includes: Supplemental data
Journal Articles

Specific T Cell Receptor Gene Repertoire Profiles in Subgroups of CLL Patients with Distinct Genomic Aberrations

Elisavet Vlachonikola, Electra Sofou, Glykeria Gkoliou, Nikos Pechlivanis, Georgios Karakatsoulis, Sabine Jeromin, Niki Stavroyianni, Pamela Ranghetti, Lydia Scarfo, Cecilia Österholm-Corbascio, Larry Mansouri, Achilles Anagnostopoulos, Paolo Ghia, Claudia Haferlach, Richard Rosenquist, Fotis Psomopoulos, Kostas Stamatopoulos, Panagiotis Baliakas, Anastasia Chatzidimitriou
Journal: Blood
Blood (2021) 138 (Supplement 1): 3749.
https://doi.org/10.1182/blood-2021-148401
Published: 2021
Journal Articles

Clonal Hematopoiesis Is Associated with Increased Risk for Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia Patients Treated with Chemo(immuno)Therapy

Maria Teresa Voso, MD, Tatjana Pandzic, PhD, Michail Iskas, MD MSc, Marija Denčić-Fekete, Eleonora De Bellis, Lydia Scarfo, Viktor Ljungström, Giovanni Del Poeta, MD, Pamela Ranghetti, Stamatia Laidou, Giulia Falconi, PhD, Silvia Imbergamo, MD, Chiara Salvetti, MD, Antonella Zucchetto, PhD, Niki Stavroyianni, Lucia Cavelier, PhD, Paolo Ghia, MD PhD, Kostas Stamatopoulos, MD, Emiliano Fabiani, PhD, Panagiotis Baliakas, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–20.
https://doi.org/10.1182/blood-2020-140232
Published: 2020
Journal Articles

Minimal Residual Disease-Driven Treatment Intensification By Sequential Addition of Ibrutinib to Venetoclax in Relapsed/Refractory Chronic Lymphocytic Leukemia: Results of the Monotherapy and Combination Phases of the Improve Study

Lydia Scarfo, Silvia Heltai, Elisa Albi, Eloise Scarano, Luana Schiattone, Lucia Farina, Gianluca Gaidano, Marina Deodato, Andrea Ferrario, Marina Motta, Gianluigi Reda, MD, Rosaria Sancetta, MD, Marta Coscia, MD PhD, Marco Ladetto, MD, Luca Laurenti, MD, Marzia Varettoni, Eleonora Perotta, Antonella Capasso, Pamela Ranghetti, Maria Colia, Paolo Ghia, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-136507
Published: 2020
Journal Articles

Ofatumumab Is Active and Safe in Patients with Relapsed/Refractory Splenic Marginal Zone Lymphoma (SMZL): Results from the Interim Analysis of an Italian Multicenter Phase 2 Study (MORE trial)

Lydia Scarfo, MD, Silvia Ferrari, Annamaria Maria Frustaci, Monica Tani, Samantha Pozzi, MD, Eloise Scarano, Maria Colia, Pamela Ranghetti, Maurilio Ponzoni, MD, Paola Ronchi, MD, Andres JM Ferreri, MD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4162.
https://doi.org/10.1182/blood-2018-99-113875
Published: 2018
Journal Articles

High Throughput Immunoprofiling of Low Count B Lymphocytosis Reveals a Distinct T Cell Receptor Repertoire from Chronic Lymphocytic Leukemia

Andreas Agathangelidis, Chrysi Galigalidou, Lydia Scarfo, Alessandra Rovida, Theodoros Moysiadis, PhD BSc, MSc, Elisavet Vlachonikola, Fotis Psomopoulos, Pamela Ranghetti, Anna Vardi, MD PhD, Kostas Stamatopoulos, Anastasia Hadzidimitriou, Paolo Ghia
Journal: Blood
Blood (2017) 130 (Supplement 1): 4296.
https://doi.org/10.1182/blood.V130.Suppl_1.4296.4296
Published: 2017
Journal Articles

CLL-Specific B Cell Receptor Immunoglobulin Stereotypes Are Very Infrequent in Low Count Monoclonal B Cell Lymphocytosis: Implications for Disease Ontogeny

Andreas Agathangelidis, Chrysi Galigalidou, Lydia Scarfo, Alessandra Rovida, Maria Gounari, Fotis Psomopoulos, Pamela Ranghetti, Katerina Gemenetzi, Frederic Davi, Kostas Stamatopoulos, Anastasia Hadzidimitriou, Paolo Ghia
Journal: Blood
Blood (2017) 130 (Supplement 1): 1710.
https://doi.org/10.1182/blood.V130.Suppl_1.1710.1710
Published: 2017
Journal Articles

Invariant NKT cells contribute to chronic lymphocytic leukemia surveillance and prognosis

Clinical Trials & Observations
Francesca Gorini, Laura Azzimonti, Gloria Delfanti, Lydia Scarfò, Cristina Scielzo, Maria Teresa Bertilaccio, Pamela Ranghetti, Alessandro Gulino, Claudio Doglioni, Arianna Di Napoli, Miriam Capri, Claudio Franceschi, Federico Caligaris-Cappio, Paolo Ghia, Matteo Bellone, Paolo Dellabona, Giulia Casorati, Claudia de Lalla
Journal: Blood
Blood (2017) 129 (26): 3440–3451.
https://doi.org/10.1182/blood-2016-11-751065
Published: 2017
Includes: Supplemental data
Journal Articles

An Innovative High-Throughput Ex Vivo Drug Assay Incorporating the Native Microenvironment Reveals a Novel Mechanism of Action of Idelalisib in CLL

Joan Ballesteros, Lydia Scarfo, Mattias Mattsson, Aliki Xochelli, Pamela Ranghetti, Daniel Primo, Alicia Robles, Julian Gorrochategui, Joaquin Martinez-Lopez, Javier De la Serna, Marcos González, MD PhD, Veerendra Munugalavadla, Richard Rosenquist, Kostas Stamatopoulos, Christophe Quéva, PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2485.
https://doi.org/10.1182/blood.V126.23.2485.2485
Published: 2015
Journal Articles

Synthetic High-Density Lipoprotein-like Nanoparticles (HDL NP) Cause Apoptosis and Enhance Killing By B-Cell Receptor and BCL-2 Inhibitors in Chronic Lymphocytic Leukemia (CLL)

Kaylin Marie McMahon, Cristina Scielzo, Lydia Scarfo, Pamela Ranghetti, Shuo Yang, Leo I. Gordon, MD, Frank Giles, MDMB, Colby Shad Thaxton, MD PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2949.
https://doi.org/10.1182/blood.V126.23.2949.2949
Published: 2015
Journal Articles

Targeting B-cell anergy in chronic lymphocytic leukemia

Benedetta Apollonio, Cristina Scielzo, Maria Teresa Sabrina Bertilaccio, Elisa ten Hacken, Lydia Scarfò, Pamela Ranghetti, Freda Stevenson, Graham Packham, Paolo Ghia, Marta Muzio, Federico Caligaris-Cappio
Journal: Blood
Blood (2013) 121 (19): 3879–3888.
https://doi.org/10.1182/blood-2012-12-474718
Published: 2013
Includes: Supplemental data