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Javier De la Serna
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Journal Articles

Efficacy and Safety of Treatment Venetoclax Monotherapy or Combined with Rituximab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) in the Real-World Setting in Spain: An Update of the Venares Study

Christelle Ferra, María José Terol, Juan Marquet Palomanes, Angel Ramírez Payer, Carol Moreno, Santiago Osorio, Fátima De la Cruz, Jose A. Garcia-Marco, Macarena Ortiz, Eduardo Rios Herranz, Laura Magnano, Sandra Iraheta, Jose Manuel Puerta, Javier de la Serna, Alicia Smucler, Jose Maria Arguiñano, Javier Loscertales, Begoña Muiña, Rubén Fernández, Tomas García, José A. Márquez, Ana Muntañola Prat, Ernesto Perez Persona, Lucrecia Yáñez, Manuel Pérez-Encinas, Marcos González Díaz, Gonzalo Caballero, María Angeles Andreu, Rafael Andreu, Ana Ruiz-Zorrilla, Diana Moreno, Patricia Baltasar
Journal: Blood
Blood (2022) 140 (Supplement 1): 9908–9910.
https://doi.org/10.1182/blood-2022-162186
Published: 2022
Journal Articles

Enduring undetectable MRD and updated outcomes in relapsed/refractory CLL after fixed-duration venetoclax-rituximab

Clinical Trials & Observations
John F. Seymour, Thomas J. Kipps, Barbara F. Eichhorst, James D’Rozario, Carolyn J. Owen, Sarit Assouline, Nicole Lamanna, Tadeusz Robak, Javier de la Serna, Ulrich Jaeger, Guillaume Cartron, Marco Montillo, Clemens Mellink, Brenda Chyla, Anesh Panchal, Tong Lu, Jenny Q. Wu, Yanwen Jiang, Marcus Lefebure, Michelle Boyer, Arnon P. Kater
Journal: Blood
Blood (2022) 140 (8): 839–850.
https://doi.org/10.1182/blood.2021015014
Published: 2022
Includes: Supplemental data
Journal Articles

Three-Year Follow-up of the Ascend Trial: Acalabrutinib Vs Rituximab Plus Idelalisib or Bendamustine in Relapsed/Refractory Chronic Lymphocytic Leukemia

Wojciech Jurczak, Andrzej Pluta, Malgorzata Wach, Daniel Lysak, Tomas Kozak, Martin Šimkovič, Iryna Kriachok, Arpad Illes, Javier de la Serna, Sean Dolan, Philip Campbell, Gerardo Musuraca, Abraham Jacob, Eric J. Avery, Jae Hoon Lee, Min Hui Wang, Ting Yu, Paolo Ghia
Journal: Blood
Blood (2021) 138 (Supplement 1): 393.
https://doi.org/10.1182/blood-2021-146570
Published: 2021
Journal Articles

Different Prognostic Impact of Recurrent Gene Mutations in IGHV-Mutated and IGHV-Unmutated Chronic Lymphocytic Leukemia: A Retrospective, Multi-Center Cohort Study By Eric, the European Research Initiative on CLL, in Harmony

Larry Mansouri, Birna Thorvaldsdottir, Lesley-Ann Sutton, Manja Meggendorfer, Ferran Nadeu, Christian Brieghel, Helen Parker, Stamatia Laidou, Riccardo Moia, Davide Rossi, Mark Catherwood, Jana Kotaskova, Julio Delgado, Ana E Rodríguez-Vicente, Rocio Benito, Gian Matteo Rigolin, Silvia Bonfiglio, Lydia Scarfo, Mattias Mattsson, Zadie Davis, Ajay Gogia, Lata Rani, Panagiotis Baliakas, Cecilia Jylhä, Aron Skaftason, Inmaculada Rapado, Fatima Miras, Joaquin Martinez-Lopez, Javier de la Serna, Jesús M Hernández Rivas, Patrick Thornton, Maria Jose Larrayoz, María José Calasanz, Zoltán Mátrai, Csaba Bodor, Karin E. Smedby, Blanca Espinet, Anna Puiggros, Ritu Gupta, Lars Bullinger, Francesc Bosch, Bárbara Tazón, Fanny Baran-Marszak, David Oscier, Florence Nguyen-Khac, Thorsten Zenz, María José Terol, Antonio Cuneo, María Hernández-Sánchez, Sarka Pospisilova, Ken I Mills, Gianluca Gaidano, Carsten Utoft Niemann, Elías Campo, Jonathan C Strefford, Paolo Ghia, Kostas Stamatopoulos, Richard Rosenquist
Journal: Blood
Blood (2021) 138 (Supplement 1): 2617.
https://doi.org/10.1182/blood-2021-150648
Published: 2021
Journal Articles

Efficacy and Safety of Treatment Venetoclax Monotherapy or Combined with Rituximab in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) in the Real -World Setting in Spain: The Venares Study

Patricia Baltasar, María José Terol, Juan Marquet Palomanes, Angel Ramírez Payer, Carol Moreno, Santiago Osorio, Fátima De la Cruz, Jose A. Garcia-Marco, Sr., Macarena Ortiz, Eduardo Ríos Herranz, Laura Magnano, Sandra Iraheta, Jose Manuel Puerta, Javier de la Serna, Alicia Smucler Simonovich, Jose Maria Arguiñano, Javier Loscertales, Begoña Muiña, Ruben Fernandez, Tomas García, José A. Márquez, Ana Muntañola Prat, Ernesto Pérez Persona, Lucrecia Yáñez, Manuel Pérez-Encinas, Marcos González Díaz, Gonzalo Caballero, María Angeles Andreu, Rafael Andreu, Ana Ruiz-Zorrilla, Diana Moreno, Christelle Ferrà
Journal: Blood
Blood (2021) 138 (Supplement 1): 1561.
https://doi.org/10.1182/blood-2021-147685
Published: 2021
Journal Articles

B-cell acute lymphoblastic leukemia in patients with chronic lymphocytic leukemia treated with lenalidomide

Clinical Trials & Observations
Moritz Fürstenau, Anna Maria Fink, Anke Schilhabel, Jonathan Weiss, Sandra Robrecht, Robert Eckert, Javier de la Serna, Marta Crespo, Marta Coscia, Candida Vitale, Sebastian Böttcher, Gesche Weppner, Matthias Ritgen, Stephan Stilgenbauer, Eugen Tausch, Kirsten Fischer, Michael Hallek, Barbara Eichhorst, Monika Brüggemann, Carmen D. Herling
Journal: Blood
Blood (2021) 137 (16): 2267–2271.
https://doi.org/10.1182/blood.2020008609
Published: 2021
Includes: Supplemental data
Journal Articles

Five-Year Analysis of Murano Study Demonstrates Enduring Undetectable Minimal Residual Disease (uMRD) in a Subset of Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL) Patients (Pts) Following Fixed-Duration Venetoclax-Rituximab (VenR) Therapy (Tx)

Arnon P. Kater, MDPhD, Thomas J. Kipps, MD PhD, Barbara Eichhorst, MD, Peter Hillmen, MBChB, PhD FRCP, FRCPath, James D'Rozario, Carolyn Owen, MDFRCPC, Sarit E Assouline, MD MSc, Nicole Lamanna, MD, Tadeusz J. Robak, Javier de la Serna, Ulrich Jaeger, Guillaume Cartron, MD PhD, Marco Montillo, Clemens Mellink, Brenda J. Chyla, Cameron Wilson, Jenny Wu, Yanwen Jiang, Marcus Lefebure, Michelle Boyer, John F. Seymour
Journal: Blood
Blood (2020) 136 (Supplement 1): 19–21.
https://doi.org/10.1182/blood-2020-136109
Published: 2020
Journal Articles

Efficacy of Subsequent Novel Targeted Therapies, Including Repeated Venetoclax-Rituximab (VenR), in Patients (Pts) with Relapsed/Refractory Chronic Lymphocytic Leukemia (R/R CLL) Previously Treated with Fixed-Duration Venr in the Murano Study

Rosemary Anne Harrup, Carolyn Owen, MDFRCPC, James D'Rozario, Tadeusz Robak, MDPhD, Arnon P. Kater, Marco Montillo, Javier de la Serna, Marek Trněný, MD, Su Young Kim, Edward Bataillard, Marcus Lefebure, Michelle Boyer, John F. Seymour
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137415
Published: 2020
Journal Articles

Four-Year Analysis of Murano Study Confirms Sustained Benefit of Time-Limited Venetoclax-Rituximab (VenR) in Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)

John F. Seymour, MBBS, PhD FRACP, Thomas J. Kipps, MD PhD, Barbara F. Eichhorst, MD, Peter Hillmen, MD PhD, James D'Rozario, MBBS, FRACP, FRCPA, Sarit Assouline, MD, Carolyn Owen, MD, Tadeusz Robak, MD, Javier de la Serna, MD PhD, Ulrich Jaeger, MD, Guillaume Cartron, Marco Montillo, MD, Nicole Lamanna, MD, Su Young Kim, MD PhD, Jenny Wu, MS, Yanwen Jiang, PhD, Jue Wang, PhD, Marcus Lefebure, PhD BSc, Michelle Boyer, PhD, Kathryn Humphrey, BSc, Arnon P Kater, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 355.
https://doi.org/10.1182/blood-2019-123930
Published: 2019
Journal Articles

Safety and Efficacy of Autologous Stem Cell Transplantation in Dialysis-Dependent Myeloma Patients - the Diadem Study from the Chronic Malignancies Working Party of the EBMT

Anna Waszczuk-Gajda, MD, Junfeng Wang, PhD, Liesbeth C. de Wreede, PhD, Tiarlan Sirait, MSc, Zubeyde Nur Ozkurt, MD, John A Snowden, BSc (Hons), MBChB, MD FRCP, FRCPath, Peter Dreger, Árpád Illés, MD D.Sc, Mutlu Arat, MD, Claude-Eric Bulabois, MD, Herrad Baurmann, MD, Matjaz Sever, MD PhD, Grzegorz W Basak, MD PhD Professor, Manos Nikolousis, MD, Victoria Potter, MD PhD, Wilfried Schroyens, MD PhD, Emmanuel Gyan, MD PhD, Gwendolyn Van Gorkom, Javier de la Serna, MD, Blandine Guffroy, Patrick J Hayden, MD, Meral Beksac, MD, Stefan O. Schönland, MD, Ibrahim Yakoub-Agha, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4574.
https://doi.org/10.1182/blood-2019-127238
Published: 2019
Journal Articles

Preliminary Results of Ibrutinib Followed By Ofatumumab Consolidation in Previously Untreated Patients with Chronic Lymphocytic Leukemia (CLL): GELLC7 Trials from the Spanish Group of CLL (GELLC)

Pau Abrisqueta, MD PhD, Eva González-Barca, MD PhD, Christelle M Ferra, Eduardo Ríos Herranz, MD, Margarita Fernandez, MD, Julio Delgado, MD, Rafael Andreu, MD, Jose Angel Hernandez-Rivas, MD PhD, Maria Jose Terol, Marcos González, Patricia Baltasar Tello, MD, Javier de la Serna, MD PhD, Angel Ramirez Payer, Carmen Ballester, MD, Carol Moreno, MD PhD, Jose A. Garcia-Marco, MD PhD, Raul Cordoba, MD PhD, Lucrecia Yanez San Segundo, MD PhD, Luis Felipe Casado Montero, MD, Francesc Bosch, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4296.
https://doi.org/10.1182/blood-2019-128470
Published: 2019
Journal Articles

Tocilizumab to Prevent Infusion-Related Events in Patients with Chronic Lymphocytic Leukemia and Co-Morbidities Treated with Obinutuzumab and Chlorambucil: Results from the Randomized Phase Ib GALACTA Trial

Ciara Louise Freeman, MRCP, MSc, FRCPath, MBBChir, Sebastian Böttcher, Javier De la Serna, Julio Delgado, Franca Falzetti, Marco Gobbi, MD, Sandra Lejniece, Maria Chiara Di Bernardo, Navita L Mallalieu, Tina Nielsen, Andrea Knapp, John G. Gribben
Journal: Blood
Blood (2018) 132 (Supplement 1): 4419.
https://doi.org/10.1182/blood-2018-99-118238
Published: 2018
Journal Articles

MURANO Trial Establishes Feasibility of Time-Limited Venetoclax-Rituximab (VenR) Combination Therapy in Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)

John F. Seymour, MBBS, PhD, Thomas J. Kipps, MD PhD, Barbara Eichhorst, Peter Hillmen, MB ChB, PhD FRCP, FRCPath, James D'Rozario, Sarit Assouline, Carolyn Owen, Tadeusz Robak, MD PhD, Javier de la Serna, Ulrich Jaeger, MD, Guillaume Cartron, Marco Montillo, MD, Nicole Lamanna, MD, Maria E. Verdugo, Elizabeth A Punnoose, Yanwen Jiang, Jue Wang, Michelle Boyer, Kathryn Humphrey, Mehrdad Mobasher, MD MPH, Arnon P. Kater, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 184.
https://doi.org/10.1182/blood-2018-184
Published: 2018
Journal Articles

Characteristics and Outcome of Older Patients with Acute Promyelocytic Leukemia Front-Line Treated with or without Arsenic Trioxide — an International Collaborative Study

Sabine Kayser, MD, Ramy Rahmé, David Martínez-Cuadron, MD, Gabriel Ghiaur, MD PhD, Xavier Thomas, MD, Marta Sobas, MD, Agnes Guerci Bresler, Salut Brunet, MD PhD, Arnaud Pigneux, MD PhD, Cristina Gil, MD, Emmanuel Raffoux, Mar Tormo, MD PhD, Norbert Vey, MD PhD, Javier de la Serna, MD, Olga Salamero, MD, Eva Lengfelder, MD, Mark J. Levis, MD, Pierre Fenaux, MD PhD, Miguel A. Sanz, MD, Richard F. Schlenk, MD, Uwe Platzbecker, Lionel Ades, MD PhD, Pau Montesinos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 80.
https://doi.org/10.1182/blood-2018-99-111768
Published: 2018
Journal Articles

Bispecific Antibodies on Hematological Malignancies: A Novel Mechanism of Action That May Contribute to Therapeutic Efficacy

Daniel Primo, PhD, Pilar Hernandez, Javier de la Serna, MD, Josep-Maria Ribera, MD, Susana Vives, MD, Juan Bergua, MD, Jaime Perez de Oteyza, MD, Josefina Serrano, MD, Julian Gorrochategui, Vicente María Luisa, David Martínez-Cuadron, MD, Pau Montesinos, MD PhD, Joaquin Martinez Lopez, MD PhD, Joan Ballesteros, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2289.
https://doi.org/10.1182/blood.V130.Suppl_1.2289.2289
Published: 2017
Journal Articles

Efficacy and Safety of Bendamustine and Rituximab As First Salvage Treatment in Chronic Lymphocytic Leukemia: Results of the Gimema-Eric LLC1315 Study

Antonio Cuneo, MD, Gian Matteo Rigolin, Alfonso Piciocchi, Carol Moreno, MD, Atto Billio, Agostino Cortelezzi, Prof, Piero Galieni, MD, Luca Laurenti, Francesca Romana Mauro, Stefano Molica, MD, Massimo Gentile, MD, Marco Montillo, MD, Livio Trentin, MD, Angeles Medina Perez, Marta Coscia, Gerardo Musuraca, MD, Lucia Farina, Alfredo Rivas-Delgado, MD, Ester Maria Orlandi, MD, Stefania Ciolli, MD, Carlo Visco, Michele Pizzuti, MD, Roberto Marasca, Monia Marchetti, MD, Francesca Re, Marcos González, MD, Annalisa Chiarenza, MD PhD, Vittorio Meneghini, Fiorella Ilariucci, Gianluca Gaidano, MD PhD, Marco Vignetti, Javier De la Serna, MD, Robin Foa, MD, George A Follows, MD PhD, Paolo Ghia
Journal: Blood
Blood (2017) 130 (Supplement 1): 4330.
https://doi.org/10.1182/blood.V130.Suppl_1.4330.4330
Published: 2017
Journal Articles

Venetoclax Plus Rituximab Is Superior to Bendamustine Plus Rituximab in Patients with Relapsed/ Refractory Chronic Lymphocytic Leukemia - Results from Pre-Planned Interim Analysis of the Randomized Phase 3 Murano Study

John F Seymour, MBBS, PhD, Thomas J. Kipps, MD, Barbara F. Eichhorst, MD, Peter Hillmen, MBChB, FRCP, FRCPath, PhD, James M. D'Rozario, MBBS FRACP FRCPA, Sarit Assouline, MD, Carolyn Jane Owen, MD FRCPC, John Gerecitano, MD PhD, Tadeusz Robak, MD PhD, Javier De la Serna, MD, Ulrich Jaeger, MD, Guillaume Cartron, MD PhD, Marco Montillo, MD, Rod Humerickhouse, MD PhD, Elizabeth Punnoose, PhD, Yan Li, PhD, Michelle Boyer, PhD, Kathryn Humphrey, BSc, Mehrdad Mobasher, MD, MPH, Arnon P. Kater, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): LBA-2.
https://doi.org/10.1182/blood.V130.Suppl_1.LBA-2.LBA-2
Published: 2017
Journal Articles

Updated Analysis of Overall Survival in Randomized Phase III Study of Idelalisib in Combination with Bendamustine and Rituximab in Patients with Relapsed/Refractory CLL

Andrew D. Zelenetz, Jennifer R. Brown, Julio Delgado, Herbert Eradat, Paolo Ghia, Abraham Jacob, Wojciech Jurczak, Javier Loscertales, Donald MacDonald, Franck Morschhauser, Javier De la Serna, Mazyar Shadman, Christopher Pocock, Adeboye Henry Adewoye, Yeonhee Kim, David Simpson, Stephan Stilgenbauer
Journal: Blood
Blood (2016) 128 (22): 231.
https://doi.org/10.1182/blood.V128.22.231.231
Published: 2016
Journal Articles

An Innovative High-Throughput Ex Vivo Drug Assay Incorporating the Native Microenvironment Reveals a Novel Mechanism of Action of Idelalisib in CLL

Joan Ballesteros, Lydia Scarfo, Mattias Mattsson, Aliki Xochelli, Pamela Ranghetti, Daniel Primo, Alicia Robles, Julian Gorrochategui, Joaquin Martinez-Lopez, Javier De la Serna, Marcos González, MD PhD, Veerendra Munugalavadla, Richard Rosenquist, Kostas Stamatopoulos, Christophe Quéva, PhD, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 2485.
https://doi.org/10.1182/blood.V126.23.2485.2485
Published: 2015
Journal Articles

Reproducible Diagnosis of Chronic Lymphocytic Leukemia (CLL) By Flow Cytometry: An European Research Initiative on CLL (ERIC) & European Society for Clinical Cell Analysis (ESCCA) Harmonisation Project

Andy C Rawstron, Karl-Anton Kreuzer, Asha Soosapilla, Martin Spacek, Peter Gambell, Neil McIver-brown, Katherina Psarra, Maria Arroz, Raffaella Milani, Javier de la Serna, M. Teresa Cedena, Ozren Jaksic, Josep F. Nomdedeu, Carol Moreno, Gian Matteo Rigolin, Antonio Cuneo, Preben Johansen, Hans Erik Johnsen, Richard Rosenquist, Carsten Utoft Niemann, Wolfgang Kern, MD, David A Westerman, Marek Trneny, Stephen P. Mulligan, Peter Hillmen, David G Oscier, Michael Hallek, MD, Paolo Ghia, MD PhD, Emili Montserrat
Journal: Blood
Blood (2015) 126 (23): 4146.
https://doi.org/10.1182/blood.V126.23.4146.4146
Published: 2015