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Journal Articles

Mitochondrial RNA Methylation By METTL17 Rewires Metabolism and Regulates Retrograde Mitochondrial-Nuclear Communication in AML

Xueer Wang, Honghai Zhang, Lei Dong, Xiaoxu Zhang, Meilin Xue, Lili Ren, Hongjie Bi, Lucy Y. Ghoda, Mark Wunderlich, James C. Mulloy, Chun-Wei David Chen, Ling Li, Lin Xu, Bin Zhang, Guido Marcucci, Steven T. Rosen, Nora Heisterkamp, Marcin Kortylewski, Jianjun Chen, Rui Su
Journal: Blood
Blood (2024) 144 (Supplement 1): 625.
https://doi.org/10.1182/blood-2024-201916
Published: 2024
Journal Articles

Clinical Characteristics and Survival Analysis of Richter Transformation: A Single Center Retrospective Study in China

Jiaojiao Zhang, Jing Luo, Lei Dong, Xiangqin Weng, Jie Xu, Jin Wang, Jian-Qing Mi
Journal: Blood
Blood (2023) 142 (Supplement 1): 6384.
https://doi.org/10.1182/blood-2023-187133
Published: 2023
Journal Articles

TET2-Mediated mRNA and DNA Oxidation in Leukemia Homing and Immune Evasion

Yangchan Li, Xiaolan Deng, Lei Dong, Li Han, Le Xuan Truong Nguyen, Jianhuang Xue, Zhicong Zhao, Wei Li, Ying Qing, Chao Shen, Brandon Tan, Zhenhua Chen, Meilin Xue, Keith Leung, Kitty Wang, Srividya Swaminathan, Ling Li, Mark Wunderlich, James C Mulloy, Bin Zhang, David A Horne, Steve T Rosen, Guido Marcucci, Mingjiang Xu, Zejuan Li, Minjie Wei, Rui Su, Jianjun Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 2975–2977.
https://doi.org/10.1182/blood-2022-162619
Published: 2022
Journal Articles

Phosphorylation Stabilized TET1 Acts As an Oncoprotein and Therapeutic Target in B-Cell Acute Lymphoblastic Leukemia

Zhenhua Chen, Keren Zhou, Jianhuang Xue, Andrew Small, Gang Xiao, Le Xuan Truong Nguyen, Zheng Zhang, Emily Prince, Hengyou Weng, Huilin Huang, Zhicong Zhao, Ying Qing, Chao Shen, Li Han, Brandon Tan, Wei Li, Rui Su, Hanjun Qin, Yangchan Li, Dong Wu, Zhaohui Gu, Vu N Ngo, Xin He, Jianfei Chao, Keith Leung, Kitty Wang, Lei Dong, Xi Qin, Zhenming Cai, Yue Sheng, Yu Chen, Xiwei Wu, Bin Zhang, Yanhong Shi, Guido Marcucci, Zhijian Qian, Mingjiang Xu, Markus Müschen, Xiaolan Deng, Jianjun Chen
Journal: Blood
Blood (2022) 140 (Supplement 1): 998–1000.
https://doi.org/10.1182/blood-2022-165469
Published: 2022
Journal Articles

Effective Novel Fto Inhibitors Show Potent Anti-Cancer Efficacy and Suppress Drug Resistance

Rui Su, PhD, Lei Dong, PhD, Yangchan Li, Li Han, Min Gao, Mark Wunderlich, MS, Xiaolan Deng, Hongzhi Li, PhD, Lei Gao, Chenying Li, MD, Sean Robison, Brandon Tan, Ying Qing, Xi Qin, Emily Prince, Jun Xie, Hanjun Qin, Yue Huang, Wei Li, Chao Shen, PhD, Jie Sun, PhD, Kulkarni Prakash, Hengyou Weng, PhD, Huilin Huang, PhD, Zhenhua Chen, PhD, Bin Zhang, PhD, Xiwei Wu, PhD, Mark J Olsen, Markus Müschen, MD PhD, Guido Marcucci, MD, Salgia Ravi, Ling Li, PhD, Caiguang Yang, Zejuan Li, MD, James C Mulloy, Minjie Wei, David A Horne, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 233.
https://doi.org/10.1182/blood-2019-124535
Published: 2019
Journal Articles

ALKBH5 Functions As an Oncogene in Acute Myeloid Leukemia

Chao Shen, PhD, Yue Sheng, PhD, Rui Su, PhD, Xiaolan Deng, Sean Robinson, Zhe Yin, MD, Lei Dong, PhD, Huilin Huang, PhD, Hengyou Weng, PhD, Chenying Li, MD, Zhijian Qian, Xi Jiang, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3910.
https://doi.org/10.1182/blood-2018-99-118988
Published: 2018
Journal Articles

Targeted Inhibition of STAT/TET1 Axis As a Potent Therapeutic Strategy for Acute Myeloid Leukemia

Xi Jiang, PhD, Chao Hu, Kyle Ferchen, Ji Nie, Xiaolong Cui, Chih-Hong Chen, PhD, Liting Cheng, Zhixiang Zuo, PhD, William Seibel, PhD, Chunjiang He, PhD, Yixuan Tang, Jennifer R Skibbe, Mark Wunderlich, MS, William C Reinhold, Lei Dong, PhD, Chao Shen, PhD, Stephen Arnovitz, Bryan Ulrich, Jiuwei Lu, PhD, Hengyou Weng, PhD, Rui Su, PhD, Huilin Huang, PhD, Yungui Wang, PhD, Chenying Li, MD, Xi Qin, James C. Mulloy, PhD, Yi Zheng, PhD, Jiajie Diao, PhD, Jie Jin, Chong Li, PhD, Paul P Liu, MD, Chuan He, PhD, Yuan Chen, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 857.
https://doi.org/10.1182/blood.V130.Suppl_1.857.857
Published: 2017
Journal Articles

CCL3 is a key mediator for the leukemogenic effect of Ptpn11 -activating mutations in the stem-cell microenvironment

Lei Dong, Hong Zheng, Cheng-Kui Qu
Journal: Blood
Blood (2017) 130 (12): 1471–1474.
https://doi.org/10.1182/blood-2017-06-791103
Published: 2017
Includes: Supplemental data
Journal Articles

TET1 Regulates DNA Replication through Targeting of Minichromosome Maintenance Genes

Hengyou Weng, PhD, Huilin Huang, PhD, Xi Qin, He Huang, PhD, Okwang Kwon, Ping Chen, Xi Jiang, PhD, Chao Hu, PhD, Hao Huang, PhD, Yungui Wang, PhD, Stephen Arnovitz, Shenglai Li, Jennifer Strong, Kyle Ferchen, Rui Su, PhD, Lei Dong, Chenying Li, Mary Beth Neilly, Zejuan Li, MD PhD, Jason Stewart, PhD, Carolyn Price, Yingming Zhao, Jianjun Chen, PhD
Journal: Blood
Blood (2016) 128 (22): 2687.
https://doi.org/10.1182/blood.V128.22.2687.2687
Published: 2016
Journal Articles

Alox5 Functions As Both Tumor Suppressor and Drug Sensitizer in AML

Xi Jiang, PhD, Yungui Wang, PhD, Chao Hu, PhD, Jennifer Strong, Lei Dong, PhD, Rui Su, PhD, Hengyou Weng, PhD, Huilin Huang, PhD, Chenying Li, Jie Jin, MD PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2016) 128 (22): 2851.
https://doi.org/10.1182/blood.V128.22.2851.2851
Published: 2016
Journal Articles

The N 6 -Adenine Methyltransferase METTL14 Plays an Oncogenic Role in Acute Myeloid Leukemia

Huilin Huang, PhD, Hengyou Weng, PhD, Xi Qin, Boxuan Simen Zhao, PhD, Lou Dore, Jennifer Strong, Rui Su, PhD, Kyle Ferchen, Chenying Li, Lei Dong, Xi Jiang, PhD, Chuan He, PhD, Jianjun Chen, PhD
Journal: Blood
Blood (2016) 128 (22): 1536.
https://doi.org/10.1182/blood.V128.22.1536.1536
Published: 2016