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Daniel Starczynowski
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Journal Articles

Heterozygous Mutations in DDX41 Cause Erythroid Progenitor Cell Defects

Timothy M Chlon, Emily Stepanchick, Analise Sulentic, Kathleen Hueneman, Daniel Starczynowski
Journal: Blood
Blood (2021) 138 (Supplement 1): 148.
https://doi.org/10.1182/blood-2021-153544
Published: 2021
Journal Articles

Preclinical Activity of the Clinical Stage Protein Arginine Methyltransferase 5 (PRMT5) Inhibitor PRT543 in Splicing Mutant Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Leya Y Schwartz, Gaurav S Choudhary, Nandini Ramachandra, Srabani Sahu, Shanisha Gordon, Bruce Ruggeri, Diane Heiser, Peggy Scherle, Daniel Starczynowski, Amit Verma
Journal: Blood
Blood (2021) 138 (Supplement 1): 2597.
https://doi.org/10.1182/blood-2021-148494
Published: 2021
Journal Articles

Momelotinib Is a Highly Potent Inhibitor of FLT3-Mutant AML

Mohammad Azhar, Zachary Kincaid, Meenu Kesarwani, Mark Wunderlich, Tahir Latif, Daniel Starczynowski, Mohammad Azam
Journal: Blood
Blood (2021) 138 (Supplement 1): 206.
https://doi.org/10.1182/blood-2021-148822
Published: 2021
Journal Articles

The Inherited MDS Gene DDX41 Is Essential for Ribosomal RNA Processing through Regulation of Snorna Biogenesis

Timothy M Chlon, PhD, Emily Stepanchick, Daniel Starczynowski, PhD, Kathleen Hueneman
Journal: Blood
Blood (2020) 136 (Supplement 1): 40.
https://doi.org/10.1182/blood-2020-143222
Published: 2020
Journal Articles

Targeted Sequencing of 7 Genes Can Help Reduce Pathologic Misclassification of MDS

Johannes B Goll, MSc, Travis L Jensen, BS, R. Coleman Lindsley, MD PhD, Rafael Bejar, MD PhD, Jason Walker, Robert Fulton, MS, Gregory A. Abel, MD MPH, Tareq Al Baghdadi, MD, H. Joachim Deeg, MD, Amy E. DeZern, MD, Benjamin L. Ebert, MDPhD, James M. Foran, MD, Edward J. Gorak, DO,MBA,MS, Steven D. Gore, MD, Rami Komrokji, MD, Jane Jijun Liu, MD, Jaroslaw P. Maciejewski, MD PhD, Eric Padron, MD, Wael Saber, MD MS, Daniel Starczynowski, PhD, Myron Waclawiw, PhD, Steffanie H. Wilson, PhD, Donnie Hebert, PhD, Harrison Reed, MSc, Nancy L. DiFronzo, PhD, Mikkael A. Sekeres, MD MS, Alexandra M. Harrington, MDMT(ASCP), Steven H. Kroft, MD, Ling Zhang, MD, Matthew J. Walter, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-140317
Published: 2020
Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 785.
https://doi.org/10.1182/blood.V130.Suppl_1.785.785
Published: 2017
Journal Articles

Tifab Deficiency Protects Against Stress-Induced Bone Marrow Failure at the Expense of Pre-Leukemic Selection

Madeline Niederkorn, BS, Melinda Varney, PhD, Ken Greis, PhD, Ruhikanta A. Meetei, PhD, Kwangmin Choi, PhD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2960.
https://doi.org/10.1182/blood.V130.Suppl_1.2960.2960
Published: 2017
Journal Articles

Innate Immune Signal Pathway Activation Induced By Combined Loss of Del(5q) MDS Genes, Tifab and Mir-146a, Accelerates Hematopoietic Stem Cell Exhaustion Driven By Chronic Exposure to a TLR Ligands

Tomoya Muto, MD PhD, Melinda Varney, PhD, Callum Walker, MSc, Lyndsey Bolanos, BSc, Kathleen Hueneman, BSc, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1674.
https://doi.org/10.1182/blood.V130.Suppl_1.1674.1674
Published: 2017
Journal Articles

Ubiquitin Editing of a Spliceosome Auxiliary Factor By TRAF6 Links Chronic TLR Signaling with Hematopoietic Defects and Myelodysplasia

Jing Fang, MD, PhD, Lyndsey Bolanos, BSc, Kwang-Min Choi, PhD, Xiaona Liu, Ms, Susanne Christie, Shailaja Akunuru, PhD, Rupali Kumar, PhD, Ken Greis, PhD, Peter Stoilov, PhD, Marie-Dominique Filippi, PhD, Jaroslaw P. Maciejewski, MD PhD, Guillermo Garcia-Manero, MD, Matthew Weirauch, PhD, Nathan Salomonis, PhD, Hartmut Geiger, PhD, Yi Zheng, PhD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2015) 126 (23): 143.
https://doi.org/10.1182/blood.V126.23.143.143
Published: 2015