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Molly A Smith
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Journal Articles

SF3B1 Mutations Induce Oncogenic IRAK4 Isoforms and Activate Targetable Innate Immune Pathways in MDS and AML

Gaurav S Choudhary, PhD, Molly A Smith, PhD, Andrea Pellagatti, Tushar D Bhagat, PhD, Shanisha Gordon, Sanjay Pandey, PhD, Nishi Shah, MBBS, MPH, Srinivas Aluri, Robert N Booher, PhD, Murali Ramachandra, PhD, Maria Elena Samson, Kith Pradhan, PhD, Teresa V. Bowman, PhD, Manoj M Pillai, MD, Chandan Guha, MBBS, Amittha Wickrema, PhD, Britta Will, PhD, Aditi Shastri, MD, Ulrich G. Steidl, MD PhD, Jacqueline Boultwood, Daniel T. Starczynowski, PhD, Amit Verma, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4224.
https://doi.org/10.1182/blood-2019-124458
Published: 2019
Journal Articles

Therapeutic Targeting of the Ubiquitin Conjugating Enzyme UBE2N in Myeloid Malignancies

Laura Barreyro, PhD, Avery Sampson, BSc, Kathleen Hueneman, BSc, Lyndsey C Bolanos, BSc, Mario Pujato, PhD, Somchai Chutipongtanate, MD PhD, Michael Wyder, MS, Wendy Haffey, PhD, Kwangmin Choi, PhD, Yaseswini Neelamraju, MS, Molly A Smith, BSc, Madeline Niederkorn, BSc, Vighnesh Ramesh, Tomoya Muto, MD PhD, Eric O'Brien, BSc, Cem Meydan, PhD, Susanne Christie, BSc, Xiaona Liu, Francine Garret-Bakelman, MD PhD, Boris Bartholdy, PhD, Britta Will, PhD, Matthew T. Weirauch, PhD, Zartash Gul, MD, Stephen Medlin, MD, John Peter Perentesis, MD, Kenneth D Greis, PhD, William Seibel, PhD, Daniel T. Starczynowski, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4050.
https://doi.org/10.1182/blood-2018-99-115359
Published: 2018
Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 785.
https://doi.org/10.1182/blood.V130.Suppl_1.785.785
Published: 2017
Journal Articles

Inhibition of UBE2N As a Therapeutic Approach in Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Laura Barreyro, PhD, Avery M Sampson, BS, Lyndsey Bolanos, BSc, Madeline Niederkorn, BS, Mario Pujato, PhD, Molly A Smith, BS, Muto Tomoya, MD PhD, Wendy D Haffey, PhD, Susanne Christie, Xiaona Liu, MD MS, Matthew Weirauch, PhD, Ken Greis, PhD, William L Seibel, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2016) 128 (22): 579.
https://doi.org/10.1182/blood.V128.22.579.579
Published: 2016
Journal Articles

Tifab , a Del(5q) MDS/AML Gene, Regulates USP15 Activity and p53

Madeline Niederkorn, BS, Melinda Varney, PhDBS, Molly A Smith, BS, Ruhikanta A. Meetei, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2016) 128 (22): 1130.
https://doi.org/10.1182/blood.V128.22.1130.1130
Published: 2016
Journal Articles

Alternative Splice Variants of IRAK4 That Activate Innate Immune Signaling Are Associated with U2AF1 Mutations in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Molly A Smith, BS, Kwangmin Choi, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, PhD, Daniel T Starczynowski, PhD
Journal: Blood
Blood (2016) 128 (22): 1531.
https://doi.org/10.1182/blood.V128.22.1531.1531
Published: 2016