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Journal Articles

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation

Blood blood.2024024505.

https://doi.org/10.1182/blood.2024024505

Published: 2024

Includes: Supplemental data

Journal Articles

Amplification of Von Willebrand Factor-Positive CALR mut Disease-Initiating Hematopoietic Stem Cells Is Associated to the Activation of the PERK/EiF2a Branch of Unfolded Protein Response

Camelia Benlabiod, Gurvan Hermange, Laetitia Borderon, Quentin Blampey, Maxime Evrard, Antonio Rodriguez Romera, Stéphanie G. Moreno, Nathalie Gault, Philippe Rameau, Cyril Catelain, Elodie Rosa, Bethan Psaila, Claus Nerlov, Sten Eirik Waelgaard Jacobsen, William Vainchenker, Hana Raslova, Paul-Henry Cournède, Isabelle Plo, Caroline Marty

Blood (2024) 144 (Supplement 1): 752.

https://doi.org/10.1182/blood-2024-205477

Published: 2024

Journal Articles

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Anna L. Brown, Claire Homan, Michael W. Drazer, Kai Yu, David Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew Pozsgai, Kelsey McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah King-Smith, Jesse JC Cheah, Mark Armstrong, Csaba Bödör, Paul Wang, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Young Rienhoff, Jr., Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Deolinda Rodrigues Pereira Velloso, Benedict Yan, Raman Sood, Amy Hsu, Steven M. Holland, Kerry Phillips, Nicola Poplawski, Milena Babic, Erika M Kwon Kim, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D Lewis, Julian Cooney, Rachel Susman, Lucy C Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Andreas W Schreiber, Christopher N Hahn, Hamish S Scott, Paul P. Liu, Lucy A. Godley

Blood (2022) 140 (Supplement 1): 4030–4033.

https://doi.org/10.1182/blood-2022-167600

Published: 2022

Journal Articles

Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms

Blood (2021) 138 (22): 2231–2243.

https://doi.org/10.1182/blood.2021010986

Published: 2021

Includes: Supplemental data

Journal Articles

Dual role of EZH2 in megakaryocyte differentiation

Stefania Mazzi, Philippe Dessen, Mathieu Vieira, Virginie Dufour, Marie Cambot, Mira El Khoury, Iléana Antony-Debré, Brahim Arkoun, Francesca Basso-Valentina, Salwa BenAbdoulahab, Valerie Edmond, Philippe Rameau, Rachel Petermann, Monika Wittner, Bruno Cassinat, Isabelle Plo, Najet Debili, Hana Raslova, William Vainchenker

Blood (2021) 138 (17): 1603–1614.

https://doi.org/10.1182/blood.2019004638

Published: 2021

Includes: Supplemental data

Journal Articles

The megakaryocyte: a cell with 3 faces as a mythic god?

William Vainchenker, Hana Raslova

Blood (2021) 138 (14): 1199–1200.

https://doi.org/10.1182/blood.2021012760

Published: 2021

Journal Articles

CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag

Francesca Basso-Valentina, Gabriel Levy, Leila N. Varghese, Myriam Oufadem, Benedicte Neven, Charlotte Boussard, Nathalie Balayn, Caroline Marty, William Vainchenker, Isabelle Plo, Paola Ballerini, Stefan N. Constantinescu, Remi Favier, Hana Raslova

Blood (2021) 138 (6): 480–485.

https://doi.org/10.1182/blood.2020010567

Published: 2021

Includes: Supplemental data

Journal Articles

Palbociclib Prevents CDK4/6 Dependent-Myeloproliferation and Myelofibrosis

Helene Duparc, Delphine Muller, Ileana Antony-Debre, PhD PharmD, Caroline Marty, PhD, Najet Debili, Jean-Luc Villeval, PhD, Isabelle Plo, William Vainchenker, Laure Gilles, PhD, Hana Raslova

Blood (2020) 136 (Supplement 1): 25.

https://doi.org/10.1182/blood-2020-141092

Published: 2020

Journal Articles

Modeling Acute Megakaryoblastic Leukemia of Down Syndrome Using Induced Pluripotent Stem Cells

Blood (2020) 136 (Supplement 1): 1.

https://doi.org/10.1182/blood-2020-140986

Published: 2020

Journal Articles

Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage

Camélia Benlabiod, Maira da Costa Cacemiro, PhD, Thomas Balligand, MD, Barbara Panneau-Schmaltz, PhD, Delphine Muller, Laure Touchard, Patrick Gonin, DVM, Jean-Luc Villeval, PhD, Stefan N Constantinescu, MD PhD, Hana Raslova, PhD, William Vainchenker, MD PhD, Isabelle Plo, Caroline Marty, PhD

Blood (2019) 134 (Supplement_1): 311.

https://doi.org/10.1182/blood-2019-127918

Published: 2019

Journal Articles

Predicting the Long-Term Efficacy of Ifnα in JAK2 V617F and Calr -Mutated MPN Patients

Blood (2019) 134 (Supplement_1): 4196.

https://doi.org/10.1182/blood-2019-127903

Published: 2019

Journal Articles

Clonal Hematopoiesis in the Molecular Landscape of Therapy-Related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers

Sabine Khalife-Hachem, Khalil Saleh, MD, Florence Pasquier, MD PhD, Anthony Tarabay, Cyril Quivoron, Sophie Cotteret, Christophe Willekens, MD, Veronique Saada, Ines-Maria Vaz-Luis, Suzette Delaloge, Alexandra Leary, Hana Raslova, PhD, Filippo Rosselli, Olivier Caron, Iléana Antony-Debre, PhD, Eric Solary, MD PhD, Stephane de Botton, MD PhD, Christophe Marzac, MD, Jean-Baptiste Micol, MD

Blood (2019) 134 (Supplement_1): 3722.

https://doi.org/10.1182/blood-2019-126872

Published: 2019

Journal Articles

Filamin A: key actor in platelet biology

Jean-Philippe Rosa, Hana Raslova, Marijke Bryckaert

Blood (2019) 134 (16): 1279–1288.

https://doi.org/10.1182/blood.2019000014

Published: 2019

Journal Articles

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

Alessandro Donada, Nathalie Balayn, Dominika Sliwa, Larissa Lordier, Valentina Ceglia, Francesco Baschieri, Cyril Goizet, Rémi Favier, Lucie Tosca, Gérard Tachdjian, Cecile V. Denis, Isabelle Plo, William Vainchenker, Najet Debili, Jean-Philippe Rosa, Marijke Bryckaert, Hana Raslova

Blood (2019) 133 (16): 1778–1788.

https://doi.org/10.1182/blood-2018-07-861427

Published: 2019

Includes: Supplemental data

Journal Articles

Differential Impact of Interferon Alpha on JAK2 V617F and Calr Mutated Hematopoietic Stem and Progenitor Cells in Classical MPN

Matthieu Mosca, PhDstudent, Lamia Lamrani, PhD, Christophe Marzac, MD, Amandine Tisserand, Valérie Edmond, PhD, Tracy Dagher, PhDstudent, Mira El-Khoury, PhD, Caroline Marty, PhD, Hugo Campario, PharmD, Nicole Casadevall, MD, Eric Solary, MD PhD, Hana Raslova, PhD, Bruno Cassinat, PharmD, PhD, Stefan N Constantinescu, MD, Jean-Jacques Kiladjian, MD PhD, Francois Girodon, MD PhD, Jean-Luc Villeval, PhD, William Vainchenker, MD PhD, Isabelle Plo, PhD

Blood (2018) 132 (Supplement 1): 4333.

https://doi.org/10.1182/blood-2018-99-114744

Published: 2018

Journal Articles

CK2: a key regulator of thrombopoiesis

William Vainchenker, Hana Raslova

Blood (2017) 130 (25): 2695–2697.

https://doi.org/10.1182/blood-2017-10-808568

Published: 2017

Journal Articles

Rare Type 1-like and Type 2-like Calrecticulin Mutants Induce Similar Myeloproliferative Neoplasms Than Type 1 and Type 2 Mutants in Mice

Katte Rao Toppaldoddi, Maira da Costa Cacemiro, Olivier Bluteau, PhD, Amélie Pioch, Barbara Panneau-Schmaltz, PhD, Delphine Muller, Nicole Casadevall, MD, Hana Raslova, PhD, Stefan N. Constantinescu, MD PhD, Isabelle Plo, William Vainchenker, MD PhD, Caroline Marty, PhD

Blood (2017) 130 (Supplement 1): 1665.

https://doi.org/10.1182/blood.V130.Suppl_1.1665.1665

Published: 2017

Journal Articles

The ETO2-GLIS2 Fusion Oncogene Alters Early Human Hematopoiesis in an Induced Pluripotent Stem Cells-Derived Model of Pediatric Acute Megakaryoblastic Leukemia

Salvatore Nicola Bertuccio, Marie Cambot, Cécile K Lopez, Larissa Lordier, Alessandro Donada, Zakia Aid, Franco Locatelli, MD PhD, Riccardo Masetti, MDPhD, William Vainchenker, MD PhD, Hana Raslova, PhD, Andrea Pession, MD, Thomas Mercher, PhD

Blood (2017) 130 (Supplement 1): 2512.

https://doi.org/10.1182/blood.V130.Suppl_1.2512.2512

Published: 2017

Journal Articles

An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L

Fabrizia Favale, Kahia Messaoudi, Leila N. Varghese, Siham Boukour, Christian Pecquet, Vitalina Gryshkova, Jean Philippe Defour, Roxana-Irina Albu, Olivier Bluteau, Paola Ballerini, Guy Leverger, Isabelle Plo, Najet Debili, Hana Raslova, Remi Favier, Stefan N. Constantinescu, William Vainchenker

Blood (2016) 128 (26): 3146–3158.

https://doi.org/10.1182/blood-2016-06-722058

Published: 2016

Includes: Supplemental data

Journal Articles

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

Anita Roy, Larissa Lordier, Stefania Mazzi, Yunhua Chang, Valérie Lapierre, Jérome Larghero, Najet Debili, Hana Raslova, William Vainchenker

Blood (2016) 128 (26): 3137–3145.

https://doi.org/10.1182/blood-2016-04-711630

Published: 2016

Includes: Multimedia, Supplemental data

NARROW

Progressive chromatin rewiring by ETO2::GLIS2 revealed in a human iPSC model of pediatric leukemia initiation

Amplification of Von Willebrand Factor-Positive CALR mut Disease-Initiating Hematopoietic Stem Cells Is Associated to the Activation of the PERK/EiF2a Branch of Unfolded Protein Response

Somatic Mutational Landscape of Hereditary Hematopoietic Malignancies Associated with Germline Variants in RUNX1 , GATA2 and DDX41

Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms

Dual role of EZH2 in megakaryocyte differentiation

The megakaryocyte: a cell with 3 faces as a mythic god?

CALR mutant protein rescues the response of MPL p.R464G variant associated with CAMT to eltrombopag

Palbociclib Prevents CDK4/6 Dependent-Myeloproliferation and Myelofibrosis

Modeling Acute Megakaryoblastic Leukemia of Down Syndrome Using Induced Pluripotent Stem Cells

Disease Phenotype and Clonal Amplification in Calreticulin del52 and ins5 Knock-in Mice Are Dependent on the Type of Mutations and Gene Dosage

Predicting the Long-Term Efficacy of Ifnα in JAK2 V617F and Calr -Mutated MPN Patients

Clonal Hematopoiesis in the Molecular Landscape of Therapy-Related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers

Filamin A: key actor in platelet biology

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

Differential Impact of Interferon Alpha on JAK2 V617F and Calr Mutated Hematopoietic Stem and Progenitor Cells in Classical MPN

CK2: a key regulator of thrombopoiesis

Rare Type 1-like and Type 2-like Calrecticulin Mutants Induce Similar Myeloproliferative Neoplasms Than Type 1 and Type 2 Mutants in Mice

The ETO2-GLIS2 Fusion Oncogene Alters Early Human Hematopoiesis in an Induced Pluripotent Stem Cells-Derived Model of Pediatric Acute Megakaryoblastic Leukemia

An incomplete trafficking defect to the cell-surface leads to paradoxical thrombocytosis for human and murine MPL P106L

Activity of nonmuscle myosin II isoforms determines localization at the cleavage furrow of megakaryocytes

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American Society of Hematology

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American Society of Hematology

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