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Journal Articles

How unique structural adaptations support and coordinate the complex function of von Willebrand factor

Peter J. Lenting, Cécile V. Denis, Olivier D. Christophe

Blood (2024) 144 (21): 2174–2184.

https://doi.org/10.1182/blood.2023023277

Published: 2024

Journal Articles

Fitusiran reduces bleeding in factor X–deficient mice

Sebastien Verhenne, Geneviève McCluskey, Hortense Maynadié, Frédéric Adam, Caterina Casari, Laurence Panicot-Dubois, Lydie Crescence, Christophe Dubois, Cécile V. Denis, Peter J. Lenting, Olivier D. Christophe

Blood (2024) 144 (2): 227–236.

https://doi.org/10.1182/blood.2023023404

Published: 2024

Includes: Multimedia, Supplemental data

Journal Articles

Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models

Stéphanie Roullet, Norman Luc, Julie Rayes, Jean Solarz, Dante Disharoon, Andrew Ditto, Emily Gahagan, Christa Pawlowski, Thibaud Sefiane, Frédéric Adam, Caterina Casari, Olivier D. Christophe, Michael Bruckman, Peter J. Lenting, Anirban Sen Gupta, Cécile V. Denis

Blood (2023) 141 (23): 2891–2900.

https://doi.org/10.1182/blood.2022018956

Published: 2023

Includes: Multimedia, Supplemental data

Journal Articles

A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD

Blood (2023) 141 (12): 1457–1468.

https://doi.org/10.1182/blood.2022017569

Published: 2023

Includes: Supplemental data

Journal Articles

von Willebrand disease: what does the future hold?

Cécile V. Denis, Sophie Susen, Peter J. Lenting

Blood (2021) 137 (17): 2299–2306.

https://doi.org/10.1182/blood.2020008501

Published: 2021

Journal Articles

A hemophilia A mouse model for the in vivo assessment of emicizumab function

Stephen Ferrière, Ivan Peyron, Olivier D. Christophe, Charlotte Kawecki, Caterina Casari, Vincent Muczynski, Amit Nathwani, Alexandre Kauskot, Peter J. Lenting, Cécile V. Denis

Blood (2020) 136 (6): 740–748.

https://doi.org/10.1182/blood.2019004334

Published: 2020

Includes: Supplemental data

Journal Articles

Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate

Blood (2019) 134 (Supplement_1): 4638.

https://doi.org/10.1182/blood-2019-128490

Published: 2019

Journal Articles

Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia

Karen Aymonnier, Charlotte Kawecki, Laurence Venisse, Yacine Boulaftali, Olivier D. Christophe, Peter J. Lenting, Véronique Arocas, Emmanuelle de Raucourt, Cécile V. Denis, Marie-Christine Bouton

Blood (2019) 134 (19): 1632–1644.

https://doi.org/10.1182/blood.2019000281

Published: 2019

Includes: Supplemental data

Journal Articles

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

Alessandro Donada, Nathalie Balayn, Dominika Sliwa, Larissa Lordier, Valentina Ceglia, Francesco Baschieri, Cyril Goizet, Rémi Favier, Lucie Tosca, Gérard Tachdjian, Cecile V. Denis, Isabelle Plo, William Vainchenker, Najet Debili, Jean-Philippe Rosa, Marijke Bryckaert, Hana Raslova

Blood (2019) 133 (16): 1778–1788.

https://doi.org/10.1182/blood-2018-07-861427

Published: 2019

Includes: Supplemental data

Journal Articles

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Reinhard Schneppenheim, Natalie Hellermann, Maria A. Brehm, Ulrike Klemm, Tobias Obser, Volker Huck, Stefan W. Schneider, Cécile V. Denis, Alexander Tischer, Matthew Auton, Winfried März, Emma-Ruoqi Xu, Matthias Wilmanns, Rainer B. Zotz

Blood (2019) 133 (4): 356–365.

https://doi.org/10.1182/blood-2018-04-843425

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

Emma-Ruoqi Xu, Sören von Bülow, Po-Chia Chen, Peter J. Lenting, Katra Kolšek, Camilo Aponte-Santamaría, Bernd Simon, Jaelle Foot, Tobias Obser, Reinhard Schneppenheim, Frauke Gräter, Cécile V. Denis, Matthias Wilmanns, Janosch Hennig

Blood (2019) 133 (4): 366–376.

https://doi.org/10.1182/blood-2018-04-843615

Published: 2019

Includes: Supplemental data

Journal Articles

The Von Willebrand Factor Tyr2561 Allele Is a Gain-of-Function Variant and a Potential Risk Factor for Early Myocardial Infarction

Reinhard Schneppenheim, MD PhD, Natalie Hellermann, MD, Maria Alexandra Brehm, PhD, Ulrike Klemm, PhD, Tobias Obser, Volker Huck, PhD, Stefan W Schneider, Cecile V. Denis, PhD, Alexander Tischer, PhD, Matthew Auton, BSc, PhD, Winfried Maerz, MD, Emma-Ruoqi Xu, PhD, Matthias Wilmanns, PhD, Rainer B. Zotz

Blood (2018) 132 (Supplement 1): 2459.

https://doi.org/10.1182/blood-2018-99-116085

Published: 2018

Journal Articles

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Blood (2018) 132 (19): 2067–2077.

https://doi.org/10.1182/blood-2018-04-845644

Published: 2018

Includes: Supplemental data

Journal Articles

A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation

Vincent Muczynski, Caterina Casari, François Moreau, Gabriel Aymé, Charlotte Kawecki, Paulette Legendre, Valerie Proulle, Olivier D. Christophe, Cécile V. Denis, Peter J. Lenting

Blood (2018) 132 (11): 1193–1197.

https://doi.org/10.1182/blood-2018-01-829523

Published: 2018

Includes: Supplemental data

Journal Articles

VWF clearance: it’s glycomplicated

Cécile V. Denis, Peter J. Lenting

Blood (2018) 131 (8): 842–843.

https://doi.org/10.1182/blood-2018-01-824904

Published: 2018

Journal Articles

Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?

Peter J. Lenting, Cécile V. Denis, Olivier D. Christophe

Blood (2017) 130 (23): 2463–2468.

https://doi.org/10.1182/blood-2017-08-801662

Published: 2017

Journal Articles

Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance

Hugues Spillemaeker, Annabelle Dupont, PhD PharmD, Alexandre Kauskot, PhD, Antoine Rauch, MD PhD, Flavien Vincent, MD, Delphine Borgel, PharmD, PhD, Alexandre Ung, Mouhamed Moussa, MD, Natacha Rousse, MD, Christophe Nix, MD, Bart Staels, PharmD, PhD, André Vincentelli, MD PhD, Cecile V. Denis, PhD, Peter J Lenting, PhD, Eric van Belle, MD PhD, Sophie Susen, MD PhD

Blood (2017) 130 (Supplement 1): 2330.

https://doi.org/10.1182/blood.V130.Suppl_1.2330.2330

Published: 2017

Journal Articles

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions

Vincent Muczynski, Gabriel Aymé, Véronique Regnault, Marc Vasse, Delphine Borgel, Paulette Legendre, Amine Bazaa, Amélie Harel, Cécile Loubière, Peter J. Lenting, Cécile V. Denis, Olivier D. Christophe

Blood (2017) 129 (17): 2443–2454.

https://doi.org/10.1182/blood-2016-06-724351

Published: 2017

Includes: Supplemental data

Journal Articles

Von Willebrand Factor Interaction with FVIII: Development of Long Acting FVIII Therapies

Peter J Lenting, PhD, Vincent Muczynski, PhD, Gabriel Aymé, PhD, Cecile V. Denis, PhD, Olivier D. Christophe, PhD

Blood (2016) 128 (22): SCI-8.

https://doi.org/10.1182/blood.V128.22.SCI-8.SCI-8

Published: 2016

Journal Articles

Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X

Vincent Muczynski, Amine Bazaa, Cécile Loubière, Amélie Harel, Ghislaine Cherel, Cécile V. Denis, Peter J. Lenting, Olivier D. Christophe

Blood (2016) 127 (6): 778–786.

https://doi.org/10.1182/blood-2015-05-647032

Published: 2016

Includes: Supplemental data

NARROW

How unique structural adaptations support and coordinate the complex function of von Willebrand factor

Fitusiran reduces bleeding in factor X–deficient mice

Efficacy of platelet-inspired hemostatic nanoparticles on bleeding in von Willebrand disease murine models

A nanobody against the VWF A3 domain detects ADAMTS13-induced proteolysis in congenital and acquired VWD

von Willebrand disease: what does the future hold?

A hemophilia A mouse model for the in vivo assessment of emicizumab function

Design and Characterization of FLT210, a Potent Next Generation AAV-hFVIII Vector Candidate

Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

The Von Willebrand Factor Tyr2561 Allele Is a Gain-of-Function Variant and a Potential Risk Factor for Early Myocardial Infarction

A mutation of the human EPHB2 gene leads to a major platelet functional defect

A factor VIII–nanobody fusion protein forming an ultrastable complex with VWF: effect on clearance and antibody formation

VWF clearance: it’s glycomplicated

Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?

Platelet Desialylation Is a Novel Mechanism of Thrombocytopenia during Mechanical Circulatory Assistance

Complex formation with pentraxin-2 regulates factor X plasma levels and macrophage interactions

Von Willebrand Factor Interaction with FVIII: Development of Long Acting FVIII Therapies

Macrophage receptor SR-AI is crucial to maintain normal plasma levels of coagulation factor X

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American Society of Hematology

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ASH Publications

American Society of Hematology

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