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Jean-Philippe Rosa
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Journal Articles

Filamin A: key actor in platelet biology

Jean-Philippe Rosa, Hana Raslova, Marijke Bryckaert
Journal: Blood
Blood (2019) 134 (16): 1279–1288.
https://doi.org/10.1182/blood.2019000014
Published: 2019
Journal Articles

Disrupted filamin A/α IIb β 3 interaction induces macrothrombocytopenia by increasing RhoA activity

Alessandro Donada, Nathalie Balayn, Dominika Sliwa, Larissa Lordier, Valentina Ceglia, Francesco Baschieri, Cyril Goizet, Rémi Favier, Lucie Tosca, Gérard Tachdjian, Cecile V. Denis, Isabelle Plo, William Vainchenker, Najet Debili, Jean-Philippe Rosa, Marijke Bryckaert, Hana Raslova
Journal: Blood
Blood (2019) 133 (16): 1778–1788.
https://doi.org/10.1182/blood-2018-07-861427
Published: 2019
Includes: Supplemental data
Journal Articles

A mutation of the human EPHB2 gene leads to a major platelet functional defect

Eliane Berrou, Christelle Soukaseum, Rémi Favier, Frédéric Adam, Ziane Elaib, Alexandre Kauskot, Jean-Claude Bordet, Paola Ballerini, Stephane Loyau, Miao Feng, Karine Dias, Abbas Muheidli, Stephane Girault, Alan T. Nurden, Ernest Turro, Willem H. Ouwehand, Cécile V. Denis, Martine Jandrot-Perrus, Jean-Philippe Rosa, Paquita Nurden, Marijke Bryckaert
Journal: Blood
Blood (2018) 132 (19): 2067–2077.
https://doi.org/10.1182/blood-2018-04-845644
Published: 2018
Includes: Supplemental data
Journal Articles

Full activation of mouse platelets requires ADP secretion regulated by SERCA3 ATPase–dependent calcium stores

Ziane Elaïb, Frédéric Adam, Eliane Berrou, Jean-Claude Bordet, Nicolas Prévost, Régis Bobe, Marijke Bryckaert, Jean-Philippe Rosa
Journal: Blood
Blood (2016) 128 (8): 1129–1138.
https://doi.org/10.1182/blood-2015-10-678383
Published: 2016
Includes: Supplemental data
Journal Articles

A new form of macrothrombocytopenia induced by a germ-line mutation in the PRKACG gene

Vladimir T. Manchev, Morgane Hilpert, Eliane Berrou, Ziane Elaib, Achille Aouba, Siham Boukour, Sylvie Souquere, Gerard Pierron, Philippe Rameau, Robert Andrews, François Lanza, Regis Bobe, William Vainchenker, Jean-Philippe Rosa, Marijke Bryckaert, Najet Debili, Remi Favier, Hana Raslova
Journal: Blood
Blood (2014) 124 (16): 2554–2563.
https://doi.org/10.1182/blood-2014-01-551820
Published: 2014
Includes: Supplemental data
Journal Articles

Platelet JNK1 is involved in secretion and thrombus formation

Frédéric Adam, Alexandre Kauskot, Paquita Nurden, Eric Sulpice, Marc F. Hoylaerts, Roger J. Davis, Jean-Philippe Rosa, Marijke Bryckaert
Journal: Blood
Blood (2010) 115 (20): 4083–4092.
https://doi.org/10.1182/blood-2009-07-233932
Published: 2010
Journal Articles

Compound Heterozygosity of a W493C Substitution and R704/Premature Stop Codon within the γ-Glutamyl Carboxylase in Combined Vitamin K-Dependent Coagulation Factor Deficiency in a French Family.

Dhouha Darghouth, PhD, Kevin W Hallgren, Odile Issertial, Amine Bazaa, PhD, Kathleen L Berkner, PhD, Jean-Philippe Rosa, MD, PhD, Rémi Favier, MD
Journal: Blood
Blood (2009) 114 (22): 1302.
https://doi.org/10.1182/blood.V114.22.1302.1302
Published: 2009
Journal Articles

PF4 and CXCL4L1, Its Non-Allelic Variant, Follow the Same Alpha Granule Storage Pathway in Megakaryocytic Cells.

Amine Bazaa, PhD, Odile Issertial, Marilyne Lebret, Jean-Philippe Rosa, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 4020.
https://doi.org/10.1182/blood.V114.22.4020.4020
Published: 2009
Journal Articles

Compound heterozygosity of novel missense mutations in the gamma-glutamyl-carboxylase gene causes hereditary combined vitamin K–dependent coagulation factor deficiency

Clinical Trials & Observations
Dhouha Darghouth, Kevin W. Hallgren, Rebecca L. Shtofman, Amel Mrad, Youssef Gharbi, Ahmed Maherzi, Radhia Kastally, Sophie LeRicousse, Kathleen L. Berkner, Jean-Philippe Rosa
Journal: Blood
Blood (2006) 108 (6): 1925–1931.
https://doi.org/10.1182/blood-2005-12-010660
Published: 2006
Includes: Supplemental data
Journal Articles

Compound Heterozygosity in the Novel Mutations W157R and T591K in the γ-Glutamyl Carboxylase Gene Causes Hereditary Combined Vitamin K-Dependent Coagulation Factor Deficiency in a Tunisian Family.

Dhouha Darghouth, Kevin W. Hallgren, PhD, Rebecca L. Hain, PhD, Amel Mrad, PhD, Youssef Gharbi, MD, Ahmed Maherzi, MD, Sophie LeRicousse, PhD, Radhia Kastally, PhD, Kathleen L. Berkner, PhD, Jean-Philippe Rosa, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2147.
https://doi.org/10.1182/blood.V106.11.2147.2147
Published: 2005
Journal Articles

P2X1: definitely not an ADP receptor

Jean-Philippe Rosa
Journal: Blood
Blood (2003) 102 (10): 3466–3467.
https://doi.org/10.1182/blood-2003-09-3040
Published: 2003
Journal Articles

Identification of a GATA-overlapping sequence within the enhancer of the murine GPIIb promoter that induces transcriptional deregulation in human K562 cells

Patricia Albanese, Marylène Leboeuf, Jean-Philippe Rosa, Georges Uzan
Journal: Blood
Blood (2000) 96 (4): 1348–1357.
https://doi.org/10.1182/blood.V96.4.1348
Published: 2000
Journal Articles

Regulation of c-Jun-NH2 Terminal Kinase and Extracellular-Signal Regulated Kinase in Human Platelets

Franck Bugaud, Florence Nadal-Wollbold, Sylviane Lévy-Toledano, Jean-Philippe Rosa, Marijke Bryckaert
Journal: Blood
Blood (1999) 94 (11): 3800–3805.
https://doi.org/10.1182/blood.V94.11.3800
Published: 1999
Journal Articles

Reassessment of Protein Tyrosine Phosphorylation in Thrombasthenic Platelets: Evidence That Phosphorylation of Cortactin and a 64-kD Protein Is Dependent on Thrombin Activation and Integrin α IIb β 3

Jean-Philippe Rosa, Valérie Artçanuthurry, Françoise Grelac, Jacques Maclouf, Jacques P. Caen, Sylviane Lévy-Toledano
Journal: Blood
Blood (1997) 89 (12): 4385–4392.
https://doi.org/10.1182/blood.V89.12.4385
Published: 1997